Name: Carbidopa
Brand: Selleck Chemicals
SKU: S1891
Availability: InStock
Rating: 5 (5 reviews)

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Quality Control

Batch: Purity: 99.91%

99.91

Related Targets	Dehydrogenase HSP Transferase P450 (e.g. CYP17) PDE phosphatase PPAR Vitamin Carbohydrate Metabolism Mitochondrial Metabolism
Other Decarboxylase Inhibitors	Benserazide HCl Ivospemin Maleic acid TES-1025 4-Bromo-3-hydroxybenzoic acid Chelidamic acid hydrate

Solubility

In vitro
Batch:

DMSO : 4 mg/mL (17.68 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Water : Insoluble

Ethanol : Insoluble

Molarity Calculator

Mass	Concentration	Volume	Molecular Weight
Mass value Mass unit	Concentration value Concentration unit	Volume value Volume unit	Molecular weight (g/mol)

Dilution Calculator Molecular Weight Calculator

In vivo batch selection In vivo Batch:
Homogeneous suspension	CMC-NA	≥5mg/ml	Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.
Homogeneous suspension	CMC-NA	≥5mg/ml	Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.
Clear solution	4%DMSO 1 Corn oil Validated by Selleck labs. Should you need adjustments to this formulation, contact our sales team for custom testing.	1.000mg/ml (4.42mM)	Taking the 1 mL working solution as an example, add 40 μL of 25 mg/ml clear DMSO stock solution to 960 μL of corn oil and mix evenly. The mixed solution should be used immediately for optimal results.

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg

Average weight of animals: g

Dosing volume per animal: μL

Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO

%

% Tween 80

% ddH₂O

% DMSO

+

%

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Molecular Weight	226.23	Formula	C₁₀H₁₄N₂O₄	Storage (From the date of receipt)	3 years-20°Cpowder
CAS No.	28860-95-9	Download SDF		Storage of Stock Solutions	1 year-80°Cin solvent 1 month-20°Cin solvent
Synonyms	N/A			SMILES	CC(CC1=CC(=C(C=C1)O)O)(C(=O)O)NN

Read more about storage stability stock solution CAS number SMILES

Mechanism of Action

Targets/IC₅₀/Ki	aromatic-L-amino-acid decarboxylase 29 μM

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2026-07-13)

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
NCT07151378	RECRUITING	PARKINSON DISEASE (Disorder)	University Hospital Tuebingen	2025-10-27	PHASE3
NCT06013956	RECRUITING	Parkinson Disease	David Escobar	2023-08-29	PHASE4
NCT05285683	RECRUITING	Chronic Pain	University of Rochester	2024-01-31	PHASE2
NCT04246437	RECRUITING	Autonomic Failure; Pure Autonomic Failure; Parkinson Disease; Multiple System Atrophy; Dementia With Lewy Bodies	Daniel Claassen	2020-02-04	PHASE1
NCT06075771	RECRUITING	Anhedonia; Depression	Emory University	2023-11-21	PHASE4
NCT06785298	RECRUITING	Parkinson Disease	Tanta University	2024-12-10	PHASE2; PHASE3

Tech Support

Handling Instructions

Tel: +1-832-582-8158 Ext:3

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Carbidopa Decarboxylase inhibitor

Chemical Structure

Molecular Weight: 226.23