For research use only. Not for use in humans.

Catalog No.S1891

1 publication

Carbidopa Chemical Structure

Molecular Weight(MW): 226.23

Carbidopa is an aromatic-L-amino-acid decarboxylase inhibitor with an IC50 of 29 ± 2 μM.

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Selleck's Carbidopa has been cited by 1 publication

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Choose Selective Decarboxylase Inhibitors

Biological Activity

Description Carbidopa is an aromatic-L-amino-acid decarboxylase inhibitor with an IC50 of 29 ± 2 μM.
aromatic-L-amino-acid decarboxylase [1]
29 μM



Solubility (25°C)

In vitro DMSO 4 mg/mL (17.68 mM)
Water Insoluble
Ethanol Insoluble
In vivo Add solvents to the product individually and in order(Data is from Selleck tests instead of citations):
4% DMSO+30% PEG 300+2% Tween 80+ddH2O
For best results, use promptly after mixing.

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 226.23


CAS No. 28860-95-9
Storage powder
in solvent
Synonyms N/A
Smiles CC(CC1=CC(=C(O)C=C1)O)(NN)C(O)=O

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Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT03887884 Completed Drug: CVT-301|Drug: Sinemet Parkinson''s Disease Acorda Therapeutics March 5 2019 Phase 1
NCT03665454 Completed Drug: PF-06412562|Drug: Standard of Care Placebo Parkinson Disease Milton S. Hershey Medical Center|Pfizer September 24 2018 Phase 1
NCT03419806 Recruiting Drug: Infudopa i.v.|Drug: Infudopa s.c.|Drug: LCIG (Duodopa) Parkinson Disease Vastra Gotaland Region|The Swedish Research Council|Dizlin Medical Design AB|Göteborg University February 16 2018 Phase 1
NCT03362879 Completed -- Parkinson''s Disease (PD) AbbVie December 14 2017 --

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID