Afatinib (BIBW2992)

Catalog No.S1011

Afatinib (BIBW2992) Chemical Structure

Molecular Weight(MW): 485.94

Afatinib (BIBW2992) inhibits EGFR/ErbB irreversibly in vitro with IC50 of 0.5, 0.4, 10, 14, 1 nM for EGFRwt, EGFR L858R , EGFR L858R/T790M ErbB2 (HER2) and ErbB4 (HER4), respectively.

Size Price Stock Quantity  
In DMSO USD 240 In stock
USD 120 In stock
USD 210 In stock
USD 570 In stock
Bulk Discount

Free Overnight Delivery on orders over $ 500
Next day delivery by 10:00 a.m. Order now.

Cited by 38 Publications

5 Customer Reviews

  • Immunoblot analysis of serum starved H2030 cells pre-treated with 500 nM or 1 µM of gefitinib, crizotinib, CP-724714, or afatinib for 12 hr, followed by stimulation with EGF, HGF, NRG1, or their combination (50 ng/ml) for 10 min.

    Nature, 2016, 534(7609):647-51. Afatinib (BIBW2992) purchased from Selleck.

    Cytoxicity of irreversible EGFR TKIS and ethacrynic acid on breast cells lines. A, Mean IC50 value of Afatinib.

    Oncotarget, 2016, 7(36):58038-58050. Afatinib (BIBW2992) purchased from Selleck.

  • Inhibition of signaling pathway activation in lung tumor cell lines by kinase inhibitors. Lung tumor cells were cultured in 10% FBS until reaching ∼80% confluence and then the cells were starved in serum-free medium for overnight, followed by 4-hour treatment with the inhibitors. Cell lysates were then prepared and used for determination of the pathway activation signals by the CEER assay.

    Int J Proteomics 2011 2011, 215496. Afatinib (BIBW2992) purchased from Selleck.

    Inhibition of anchorage-independent growth of lung tumor cell lines by selected inhibitors. Each selected cell line was treated with the indicated inhibitor at 0.1 μM and 1 μM concentrations for two weeks and cell colony size formation was scored under the Nikon inverted-phase microscope.

    Int J Proteomics 2011 2011, 215496. Afatinib (BIBW2992) purchased from Selleck.

  • After starved in serum-free medium for 24h, Breast cancer cells incubated with the indicated concentrations of BIBW2992 for 3h,followed by 15-minute stimolation of 100ng/ml EGF

    Dr. Zhang of Tianjin Medical University. Afatinib (BIBW2992) purchased from Selleck.

Purity & Quality Control

Choose Selective EGFR Inhibitors

Biological Activity

Description Afatinib (BIBW2992) inhibits EGFR/ErbB irreversibly in vitro with IC50 of 0.5, 0.4, 10, 14, 1 nM for EGFRwt, EGFR L858R , EGFR L858R/T790M ErbB2 (HER2) and ErbB4 (HER4), respectively.
Targets
EGFR (L858R) [1]
(Cell-free assay)
EGFR (wt) [1]
(Cell-free assay)
ErbB4 [2]
(Cell-free assay)
EGFR (L858R/T790M) [1]
(Cell-free assay)
HER2 [1]
(Cell-free assay)
0.4 nM 0.5 nM 1 nM 10 nM 14 nM
In vitro

BIBW2992 shows potent activity against both wild-type and mutant forms of EGFR and HER2. It is similar to Gefitinib in potency against L858R EGFR, but about 100-fold more active against the Gefitinib resistant L858R-T790M EGFR double mutant. BIBW2992 exhibits potent effects on both EGFR and HER2 phosphorylation in vivo. It compares favorably to reference compounds (such as Lapatinib et al.) in all cell types tested, such as human epidermoid carcinoma cell line A431 expressing wt EGFR, murine NIH-3T3 cells transfected with wt HER2, as well as breast cancer cell line BT-474 and gastric cancer cell line NCI-N87, which express endogenous HER2. [1]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
HDLM-2 MWXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHP3[ZRKSzVyPUCuNFA2PzJizszN NHrDdHpUSU6JRWK=
KASUMI-1 MX7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlvQTWM2OD1yLkCwPVEyKM7:TR?= NFvXNXdUSU6JRWK=
HCC2218 NFX3elJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYfGOlZwUUN3ME2wMlAxQTh5IN88US=> M2n5W3NCVkeHUh?=
KARPAS-45 NXvOeFBCT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlHuTWM2OD1yLkCxOlcyKM7:TR?= NWTGPZg6W0GQR1XS
HSC-4 MYHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2m2SGlEPTB;MD6wNVc1QCEQvF2= MkW1V2FPT0WU
CHL-1 NXnISpVyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2izWmlEPTB;MD6wNVg{QSEQvF2= MWHTRW5ITVJ?
KY821 NVPFOZBJT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFjKPXJKSzVyPUCuNFIxPiEQvF2= MkDRV2FPT0WU
NCI-N87 Mn7BS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NE\SR25KSzVyPUCuNFI4PzNizszN NIfWc3NUSU6JRWK=
DOK MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NIrXWVJKSzVyPUCuNFMyQTRizszN NGLXcFJUSU6JRWK=
DSH1 NEXZOWNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXSzdFI4UUN3ME2wMlA{OzF2IN88US=> MUHTRW5ITVJ?
MDA-MB-175-VII MVvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXf2bXB7UUN3ME2wMlA{PDF4IN88US=> NXL1WoFLW0GQR1XS
NCI-H2170 MV3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGjPR3FKSzVyPUCuNFM4OjhizszN NXWzcYRwW0GQR1XS
BT-474 NFjLWVdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1fCeWlEPTB;MD6wOFk5PiEQvF2= NVPxfWhXW0GQR1XS
EFO-27 MoX3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFLRbHFKSzVyPUCuNFUyQDJizszN M{G5OHNCVkeHUh?=
NCI-H720 NI[0XYFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYDvRnFHUUN3ME2wMlA2OzJ3IN88US=> MYXTRW5ITVJ?
PC-14 MoP6S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{npWWlEPTB;MD6wOVY3QCEQvF2= NEXvXW9USU6JRWK=
EC-GI-10 NYPYWZJnT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYT3bGIxUUN3ME2wMlA2QTF{IN88US=> NX7HPHZlW0GQR1XS
KYSE-450 NEf4UI5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NG\qdYNKSzVyPUCuNFU6PzhizszN M{TwOXNCVkeHUh?=
BPH-1 NWT0T5EzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{fhUGlEPTB;MD6wOVk5QCEQvF2= NY\JS3F1W0GQR1XS
NCI-H292 MoPVS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVjnfFRVUUN3ME2wMlA3ODlizszN M{HrUnNCVkeHUh?=
H9 NXXseIFpT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFz2OYlKSzVyPUCuNFcyOzJizszN MVTTRW5ITVJ?
NCI-H526 MX7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NI\ieHNKSzVyPUCuNFc5OjNizszN Ml7nV2FPT0WU
NCI-H1623 M4rLTGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYnJR|UxRTBwMEiwNlUh|ryP MWLTRW5ITVJ?
KYSE-140 MXHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYXJR|UxRTBwMEizN{DPxE1? NVzNcZJiW0GQR1XS
Ca9-22 MVvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYnJR|UxRTBwMEizOVMh|ryP MXHTRW5ITVJ?
AU565 MkPIS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1PkfmlEPTB;MD6wPFUxPCEQvF2= M3uyUXNCVkeHUh?=
ZR-75-30 Mn3JS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MkHjTWM2OD1yLkC5OVQ2KM7:TR?= M3\neXNCVkeHUh?=
NCI-H1770 M3PmWGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnG0TWM2OD1yLkGwNlgh|ryP M1ztXXNCVkeHUh?=
LB2241-RCC MWPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYXJR|UxRTBwMUC4PFQh|ryP Mni5V2FPT0WU
CAL-39 NY\yfI0zT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYnJR|UxRTBwMUG3PVIh|ryP NX;rSZY5W0GQR1XS
UACC-893 MVHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2L2RmlEPTB;MD6xNVg5PSEQvF2= MUfTRW5ITVJ?
LU-65 NXzu[IpOT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mlj1TWM2OD1yLkGyOlM{KM7:TR?= MXfTRW5ITVJ?
HN M{HKNGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFTkZZVKSzVyPUCuNVMxPzdizszN M3rFNXNCVkeHUh?=
TI-73 MY\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{XR[2lEPTB;MD6xOFcyPSEQvF2= M1vwbHNCVkeHUh?=
KU812 MnvGS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYfLWWNCUUN3ME2wMlE2PDV4IN88US=> Mn;YV2FPT0WU
SW13 MWXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVjhflU1UUN3ME2wMlE3OjF4IN88US=> NFjGTJBUSU6JRWK=
BB30-HNC NFP0UnBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYXqNnJOUUN3ME2wMlE3PTd4IN88US=> NX3kVJZyW0GQR1XS
HSC-2 NGG3R3NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MoHDTWM2OD1yLkG2PFM4KM7:TR?= M1PkbXNCVkeHUh?=
BV-173 MkD0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFj3OYJKSzVyPUCuNVc2QTZizszN MmLOV2FPT0WU
CAL-27 NVTvTpdLT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIT2bo9KSzVyPUCuNVc3OzZizszN NXfVRlZIW0GQR1XS
SBC-1 MlLMS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NH3CUXZKSzVyPUCuNVg6PTlizszN NELERZFUSU6JRWK=
CAL-33 MlnJS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYXJR|UxRTBwMkCxPFQh|ryP NXTMcoZkW0GQR1XS
NCI-H209 NGnrdlBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mo\wTWM2OD1yLkKwOFYh|ryP MUPTRW5ITVJ?
COR-L105 MUnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmXkTWM2OD1yLkKxNFg1KM7:TR?= NGL0[HZUSU6JRWK=
HSC-3 NH3sRVdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYnJR|UxRTBwMkGxPVgh|ryP MWPTRW5ITVJ?
NCI-H69 M{f4dWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGTGXWtKSzVyPUCuNlE1PTFizszN NHXycIpUSU6JRWK=
MOLT-13 M2nES2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mn\aTWM2OD1yLkKzPVc2KM7:TR?= MlXmV2FPT0WU
ML-2 M3XRXGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1TiV2lEPTB;MD6yOFgxOiEQvF2= MkfrV2FPT0WU
IGROV-1 Mo\mS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mmm5TWM2OD1yLkK1PVUzKM7:TR?= MX;TRW5ITVJ?
TK10 MYnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NH3CR3dKSzVyPUCuNlY4OzhizszN MkjjV2FPT0WU
EoL-1-cell NX\xTVNFT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEL5b5hKSzVyPUCuNlY5QTJizszN MXzTRW5ITVJ?
HO-1-N-1 Ml\TS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1jkT2lEPTB;MD6yO|g2OyEQvF2= NUPhZ|NGW0GQR1XS
BHY M1GzVWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mn\rTWM2OD1yLkK4OlU2KM7:TR?= NFzuRYhUSU6JRWK=
LU-139 MnzXS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUfJR|UxRTBwM{C1NUDPxE1? MkTHV2FPT0WU
23132-87 NF;mUW9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGH0SVRKSzVyPUCuN|E6OjNizszN NXn5UIxLW0GQR1XS
ACHN MYfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Ml36TWM2OD1yLkOxPVk1KM7:TR?= MmXQV2FPT0WU
DoTc2-4510 MlTsS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MV3JR|UxRTBwM{KyNVkh|ryP M{LDfHNCVkeHUh?=
BB65-RCC MlqyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M17VUmlEPTB;MD6zOFU6OyEQvF2= NXvJe3p5W0GQR1XS
HLE MUfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUTJR|UxRTBwM{WwOFYh|ryP NXq4bFNoW0GQR1XS
HCC1419 NGjWVWdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFvDdHhKSzVyPUCuN|Y1ODhizszN M{TPV3NCVkeHUh?=
A388 NGDSU45Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2nDcWlEPTB;MD6zOlg2PyEQvF2= MU\TRW5ITVJ?
NUGC-3 NH\NdWVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mn\tTWM2OD1yLkO4N|c{KM7:TR?= NVj0SZRVW0GQR1XS
KYSE-180 Mor1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NX\Ic2lSUUN3ME2wMlM6ODh7IN88US=> MV3TRW5ITVJ?
TE-6 NYDQTI5WT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MofGTWM2OD1yLkSwNlQ3KM7:TR?= M2DyXXNCVkeHUh?=
A498 NISzOndIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2rSRmlEPTB;MD60NFY4PCEQvF2= MXzTRW5ITVJ?
NCI-H1648 NXrmc3Y5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MU\JR|UxRTBwNESxPFIh|ryP NVXLPVhZW0GQR1XS
DU-145 NX34WlZjT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWTJR|UxRTBwNES4N|Mh|ryP NU\HXop6W0GQR1XS
CW-2 M3rxcGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEjnRnpKSzVyPUCuOFY6OTRizszN M3rlNHNCVkeHUh?=
A431 MVPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWH3e2c4UUN3ME2wMlQ5OjN|IN88US=> M{LlcnNCVkeHUh?=
SAS MYfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4qy[mlEPTB;MD60PFM6QCEQvF2= M1zKbXNCVkeHUh?=
NCI-H2126 NVTXfo54T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUTJR|UxRTBwNUG5NlYh|ryP Mm\nV2FPT0WU
NCI-H358 M2myVWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NX\tWJpJUUN3ME2wMlU{OjFizszN NGTkWFRUSU6JRWK=
FADU NIHYcphIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGLhbpNKSzVyPUCuOVQ1ODRizszN Mo\4V2FPT0WU
ACN NVW3cYZLT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NI\MOXFKSzVyPUCuOVUxQTRizszN MkPVV2FPT0WU
HCC70 M1rhSWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYLJR|UxRTBwNUe2OlEh|ryP NE\Qb2ZUSU6JRWK=
NCI-H1838 MkO4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXLJR|UxRTBwNkCyPVkh|ryP NEPYbJVUSU6JRWK=
CAL-54 NF22e4xIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1vkVmlEPTB;MD62NVYzOSEQvF2= NUDEb4hGW0GQR1XS
NCI-H1975 NF;VSI9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4m3OWlEPTB;MD62NVczQCEQvF2= NHHDc3FUSU6JRWK=
COR-L88 NHPUd3lIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlHaTWM2OD1yLk[0NVE{KM7:TR?= NUTyUYd4W0GQR1XS
CTV-1 NUPJNYVbT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkLhTWM2OD1yLk[0N|kzKM7:TR?= MnWzV2FPT0WU
EW-18 MmXWS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{O1UGlEPTB;MD62PFY6QCEQvF2= M1HQcHNCVkeHUh?=
HCC1806 M3nNPWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NUC2RYVxUUN3ME2wMlY6PjZ4IN88US=> M3fkNHNCVkeHUh?=
HuP-T4 MUTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYDJR|UxRTBwNkm3OkDPxE1? NV61NWNLW0GQR1XS
MDA-MB-361 MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlXPTWM2OD1yLkeyOlYzKM7:TR?= NVG1RXR[W0GQR1XS
NCI-H1573 M2GyOWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFix[2xKSzVyPUCuO|M3OyEQvF2= M3nyUHNCVkeHUh?=
KU-19-19 MlHGS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NU\DTnltUUN3ME2wMlc4PDZ2IN88US=> MYLTRW5ITVJ?
COLO-678 MX\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M37remlEPTB;MD64NFg{PCEQvF2= MoXUV2FPT0WU
C-33-A NUThbpVnT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4C4PGlEPTB;MD64NVI6PyEQvF2= MkLlV2FPT0WU
Calu-3 MkSwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmLsTWM2OD1yLkixOFM1KM7:TR?= M3SwTnNCVkeHUh?=
AGS M1XIb2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIjjeYJKSzVyPUCuPFM3PDhizszN MlHWV2FPT0WU
SCC-25 MlruS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIT3SoZKSzVyPUCuPFQyPzFizszN MU\TRW5ITVJ?
JVM-2 M1jtOGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M13LbGlEPTB;MD64PFI6QSEQvF2= MkfYV2FPT0WU
HCE-T M331Z2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NF7qdoZKSzVyPUCuPFg1OjhizszN MX;TRW5ITVJ?
ES4 NGTDU5JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXjnb4YyUUN3ME2wMlk4QDN4IN88US=> NXXwVVJFW0GQR1XS
EKVX NH71NI5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MoHXTWM2OD1zLkCxNFY1KM7:TR?= M4DRV3NCVkeHUh?=
D-542MG NWG5WGE{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{DL[2lEPTB;MT6wNVA3PCEQvF2= MX7TRW5ITVJ?
SW1116 M4KxUGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYrJR|UxRTFwMEGyPFch|ryP NIfzTlFUSU6JRWK=
5637 NVi1WVNwT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2PoPWlEPTB;MT6wNVUyKM7:TR?= MWLTRW5ITVJ?
HT-1376 MkDXS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWHSfXIzUUN3ME2xMlAyPTF|IN88US=> NIH2PHVUSU6JRWK=
NB69 MWDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3WzZmlEPTB;MT6wNlk1PSEQvF2= MX;TRW5ITVJ?
YKG-1 MXXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Ml\ITWM2OD1zLkC1OFE6KM7:TR?= MoLmV2FPT0WU
EW-3 MU\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MY\JR|UxRTFwMEe4PFMh|ryP NFPX[JdUSU6JRWK=
GCIY NHPP[mtIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NH;nPVJKSzVyPUGuNFgyODRizszN MXXTRW5ITVJ?
SK-MES-1 NF;QSZBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUfJR|UxRTFwMUG0PFch|ryP MkL6V2FPT0WU
PANC-08-13 MnvPS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Ml7CTWM2OD1zLkG2OFE3KM7:TR?= NUDVblFjW0GQR1XS
SK-NEP-1 M3r1WGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1LV[mlEPTB;MT6xO|UyOyEQvF2= MmKxV2FPT0WU
SW954 M1eybGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVnJR|UxRTFwMkCyNVQh|ryP NFTOO5lUSU6JRWK=
NCI-SNU-5 MkHxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVTTW2N2UUN3ME2xMlI{QSEQvF2= NIHtcmxUSU6JRWK=
SW48 M1;OOmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVXJR|UxRTFwMkW0N|Ih|ryP MVzTRW5ITVJ?
HT-3 M130V2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmXyTWM2OD1zLkK4O|U{KM7:TR?= NGm0O3FUSU6JRWK=
ETK-1 NEHxWXFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MkLXTWM2OD1zLkO3OFU3KM7:TR?= MYDTRW5ITVJ?
SCC-15 MmKwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYLJR|UxRTFwM{m0OVEh|ryP NGm0XYlUSU6JRWK=
DU-4475 M4rifWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2TGXmlEPTB;MT60NFEzOSEQvF2= NVraTVlGW0GQR1XS
NB5 NH\nd5VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MonUTWM2OD1zLkSxN|E4KM7:TR?= M2fjOHNCVkeHUh?=
CFPAC-1 Mny2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1\QR2lEPTB;MT60NlQ6OyEQvF2= M4nhdnNCVkeHUh?=
NCI-H630 NGryRXhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MX7JR|UxRTFwNEW1PFIh|ryP Mk\BV2FPT0WU
NCI-H82 M3XUVGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWTJR|UxRTFwNUSwNFYh|ryP NUnk[pJGW0GQR1XS
ECC10 NWLqWlkzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWXJR|UxRTFwNUWzOlkh|ryP MknTV2FPT0WU
K5 MlniS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFnQc|FKSzVyPUGuOVg{PTdizszN NFvLXZFUSU6JRWK=
ME-180 M13md2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEDMXZNKSzVyPUGuOlExQTZizszN M2TWR3NCVkeHUh?=
KYSE-410 M3zuNWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmLaTWM2OD1zLk[1OlczKM7:TR?= MUPTRW5ITVJ?
G-401 NIrXR2xIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVzkS5Q1UUN3ME2xMlY4PDF|IN88US=> MljZV2FPT0WU
TGBC24TKB MXPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NELEXHNKSzVyPUGuOlgzOyEQvF2= NGjERpdUSU6JRWK=
Detroit562 NYDqXJM6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVXZWYR5UUN3ME2xMlcxOTV{IN88US=> NU[4[m4xW0GQR1XS
OE19 MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3uzVGlEPTB;MT63NVUyOiEQvF2= NYSyZ3U{W0GQR1XS
CAKI-1 M4fXZ2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NETxO4xKSzVyPUGuO|gzOTFizszN NFnRUWpUSU6JRWK=
TE-12 Mn:yS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mo\STWM2OD1zLkiwOFE1KM7:TR?= NHPCXnRUSU6JRWK=
NCI-H1666 M3jIeGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUXJR|UxRTFwOEC5OFgh|ryP NITHOlhUSU6JRWK=
TE-1 M4DhVWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NH3NVGNKSzVyPUGuPFE1PzVizszN MUfTRW5ITVJ?
CAL-12T MoTnS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXvRdpJoUUN3ME2xMlg5QTR3IN88US=> NXvCT5lHW0GQR1XS
TE-8 M3ziWmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoXVTWM2OD1zLkmxN|c4KM7:TR?= NEK2fGxUSU6JRWK=
KYSE-270 MnXrS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWTZdnNDUUN3ME2yMlAzPzN{IN88US=> MWHTRW5ITVJ?
GMS-10 NEXmTFNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3juTWlEPTB;Mj6wN|UyPyEQvF2= MYLTRW5ITVJ?
A2780 Mn7ZS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUHJR|UxRTJwME[yPVQh|ryP MUPTRW5ITVJ?
OMC-1 NInNOGJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MX7JR|UxRTJwMEixOlkh|ryP NWX4SIFGW0GQR1XS
LoVo NV\iO|JoT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NW\N[2dPUUN3ME2yMlExPzl5IN88US=> Mlq1V2FPT0WU
PANC-03-27 NG\acJpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIK1UolKSzVyPUKuNVY3OzFizszN NYjvcFZsW0GQR1XS
MDA-MB-157 MWPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYPBNJpsUUN3ME2yMlIyQDJ6IN88US=> M2KwenNCVkeHUh?=
CaR-1 NESxOnlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUjIenpzUUN3ME2yMlI5OjhzIN88US=> NEfoU2tUSU6JRWK=
769-P NXPFPHlJT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXPJR|UxRTJwMkmwN|ch|ryP NIn6TZRUSU6JRWK=
NB7 NYexdoVqT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYDJR|UxRTJwMkm2O|Yh|ryP NVi5TWloW0GQR1XS
MKN7 MVPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MV3JR|UxRTJwM{WzN|Uh|ryP NWXNZYtbW0GQR1XS
NCI-H1048 NGDVW2tIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2\2VWlEPTB;Mj60PVE2QCEQvF2= NXfUc3p4W0GQR1XS
RCM-1 NVn2c4lUT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NH3ZZ2lKSzVyPUKuOVI6OzhizszN Mn\EV2FPT0WU
HT55 NXr6TmZyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVHmcoplUUN3ME2yMlU4OzhizszN NXv6UHRQW0GQR1XS
HCC1569 MV;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVHQR4k{UUN3ME2yMlU5Ojl5IN88US=> NH3JNW5USU6JRWK=
LXF-289 NGHC[GVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXnXVo93UUN3ME2yMlY{PTZ3IN88US=> M4HabXNCVkeHUh?=
OVCAR-3 MmfKS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MV;JR|UxRTJwNkexOlch|ryP NFjBRYZUSU6JRWK=
TE-10 MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVfkdHd2UUN3ME2yMlY5ODd6IN88US=> NH\QU|RUSU6JRWK=
SNU-C2B M3Gwfmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkHxTWM2OD1{Lk[4OlE3KM7:TR?= M1rCUnNCVkeHUh?=
LB1047-RCC MlnnS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MULJR|UxRTJwN{S4PFgh|ryP NVLRWFROW0GQR1XS
SN12C NHznSnBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NF3jVIpKSzVyPUKuPVE6PjRizszN NYTyWJdwW0GQR1XS
786-0 NFjxbZBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnjzTWM2OD1|LkC2OFA5KM7:TR?= NW\sXFVOW0GQR1XS
HT-29 NYjueoE5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2PhOWlEPTB;Mz6wO|MxQSEQvF2= MkW0V2FPT0WU
RPMI-7951 M4HheWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFPqV4lKSzVyPUOuNFc2QSEQvF2= NYewb5N{W0GQR1XS
NBsusSR MVrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWP5e4tFUUN3ME2zMlE5OjV2IN88US=> NIH5cYtUSU6JRWK=
NKM-1 M3X1RWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnPoTWM2OD1|LkG4O|Q1KM7:TR?= NXjDNnV{W0GQR1XS
Capan-2 NUPk[WFmT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXqzSW5WUUN3ME2zMlQ3QDd3IN88US=> NXTkRpdwW0GQR1XS
MKN1 NUDrUo55T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVLhN2tyUUN3ME2zMlQ4OTB6IN88US=> NUDLc|FCW0GQR1XS
OAW-42 MUXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVK0fYpwUUN3ME2zMlUxODJ4IN88US=> NFfmbHlUSU6JRWK=
SKG-IIIa NH3WVXlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWPJR|UxRTNwNUKyN|ch|ryP NWTqVo9rW0GQR1XS
no-11 NV\adnVET3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlviTWM2OD1|LkWzOVY1KM7:TR?= NHuwbphUSU6JRWK=
NY MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXTJR|UxRTNwNUO2OVUh|ryP M3nZZ3NCVkeHUh?=
HEC-1 NV7sWXFKT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGHVR5lKSzVyPUOuOVg6PSEQvF2= Mm\CV2FPT0WU
NCI-H441 NXnSPVI3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmPDTWM2OD1|LkW5PFQyKM7:TR?= NWjWXlBDW0GQR1XS
NCI-H2009 MVXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NUHWbYdHUUN3ME2zMlYyOjF4IN88US=> M1nuU3NCVkeHUh?=
T47D NHGxTFBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M33zPGlEPTB;Mz62NlIyPyEQvF2= NHfxOG5USU6JRWK=
SNU-449 NVrv[phrT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVfJR|UxRTNwNkW4NlYh|ryP M{\wdnNCVkeHUh?=
NCI-SNU-1 MYnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVPJR|UxRTNwNkm3N|Uh|ryP M2rFVnNCVkeHUh?=
BT-20 MXvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MojaTWM2OD1|Lk[5O|k2KM7:TR?= MUDTRW5ITVJ?
LS-123 NU\rRWNvT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHjF[W9KSzVyPUOuO|QzQDRizszN NUnuOFlrW0GQR1XS
8305C NFXjPWZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmTMTWM2OD1|Lke1PVEyKM7:TR?= NVG0OYVTW0GQR1XS
OCUB-M MX3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{HOPWlEPTB;Mz63OlE5PyEQvF2= MXzTRW5ITVJ?
KOSC-2 MXzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUDJR|UxRTNwOEO0OVEh|ryP NW[3UplLW0GQR1XS
NCI-H1693 M3uwbGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MojBTWM2OD1|Lki0NVgyKM7:TR?= MojUV2FPT0WU
TE-9 M3XIXWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4DUSGlEPTB;Mz64OFM5OiEQvF2= NInG[nFUSU6JRWK=
MV-4-11 NIWybo9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIXqTXlKSzVyPUOuPFc6QTRizszN MnHMV2FPT0WU
GAMG NWXCd3Z6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmDWTWM2OD1|LkmxN|E1KM7:TR?= MoPlV2FPT0WU
KNS-62 M3mydWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGLnd4RKSzVyPUOuPVQ4OzFizszN MXvTRW5ITVJ?
MC116 NFfzcoRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYXJR|UxRTNwOUW0PFkh|ryP NV6yd3ZDW0GQR1XS
647-V M2rBcWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoDPTWM2OD1|Lkm4OFUzKM7:TR?= MmfCV2FPT0WU
U-87-MG NEHrcmFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2TUU2lEPTB;ND6xNFQ5OSEQvF2= MlzGV2FPT0WU
RPMI-8226 NFn1O29Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mm\lTWM2OD12LkGxOlMyKM7:TR?= M1u1TnNCVkeHUh?=
SW1417 MlvmS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NI\sUGNKSzVyPUSuNVIyPDdizszN NYj4UplWW0GQR1XS
LAMA-84 MofiS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NV\PfJRQUUN3ME20MlE4ODJizszN MnPkV2FPT0WU
LS-513 NX61fWZlT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFfrNoFKSzVyPUSuN|EzOTdizszN MnnGV2FPT0WU
KLE M{H0V2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVHJR|UxRTRwNEC4NVkh|ryP NX:ySnllW0GQR1XS
HCT-116 MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Ml\6TWM2OD12LkSxNFA4KM7:TR?= NVTWdmFzW0GQR1XS
EPLC-272H MljYS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFzkeXVKSzVyPUSuOFE2OzNizszN MVXTRW5ITVJ?
KS-1 NHPpeYhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWj4bIdoUUN3ME20MlUxQDh7IN88US=> MYfTRW5ITVJ?
HT-1197 M2nQTmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYTJR|UxRTRwNUK2Olkh|ryP MVTTRW5ITVJ?
LCLC-97TM1 MWnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1H3b2lEPTB;ND61N|Y5PiEQvF2= NEfsTGpUSU6JRWK=
ES5 NEHmfZNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NH;sTphKSzVyPUSuPFM4OjNizszN NVr1UFhoW0GQR1XS
CTB-1 MU\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYHJR|UxRTRwOES4PEDPxE1? M1nXbHNCVkeHUh?=
HL-60 NVS2fphlT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NH\PZnJKSzVyPUSuPFY3OTFizszN MoS4V2FPT0WU
VM-CUB-1 NWPBXG5vT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUjHPFhxUUN3ME20Mlg3QDF7IN88US=> MYLTRW5ITVJ?
MEG-01 NILoU2JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFv5OoFKSzVyPUSuPVk1ODNizszN Mkn3V2FPT0WU
KYSE-520 NU\Rb2Z6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVfJR|UxRTVwMkC4N|kh|ryP MUnTRW5ITVJ?
HuO-3N1 MojBS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVzJR|UxRTVwMkSwOFMh|ryP MUXTRW5ITVJ?
SW620 MUDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWnYdZQzUUN3ME21MlI1QTZ2IN88US=> MmD2V2FPT0WU
U031 M4XPfmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{nMXGlEPTB;NT6yOVQzPCEQvF2= MUTTRW5ITVJ?
TE-5 M4LZe2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVf4[mhzUUN3ME21MlQxQDVizszN M1O1SHNCVkeHUh?=
NCI-H747 MUTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHXFVFlKSzVyPUWuOFI1PzJizszN Mo\qV2FPT0WU
MG-63 M4jqSWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkTaTWM2OD13LkS4O|YzKM7:TR?= MWPTRW5ITVJ?
HC-1 MV3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlHiTWM2OD13LkWxPFM6KM7:TR?= Ml\VV2FPT0WU
HCC2998 NUKwfodoT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2m5dmlEPTB;NT61NlYyPSEQvF2= NXW1epVPW0GQR1XS
NTERA-S-cl-D1 NHrxXXpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MoCxTWM2OD13LkW0OVM4KM7:TR?= M1vxNnNCVkeHUh?=
KINGS-1 MXvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHrsW3dKSzVyPUWuOlA6PDRizszN MofrV2FPT0WU
D-423MG M1P0PWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYPvSJZCUUN3ME21MlYyPzB3IN88US=> NFjmRVlUSU6JRWK=
SW962 Mn3SS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWWwVWd5UUN3ME21MlYzODN{IN88US=> MX7TRW5ITVJ?
LOXIMVI Ml3yS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NF\jZ3lKSzVyPUWuOlM5PzNizszN NHTMPWVUSU6JRWK=
LS-411N M3\KfWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NV7Eb5huUUN3ME21Mlc6PDRzIN88US=> MkjoV2FPT0WU
NCI-H2291 NGPk[|VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXOySXdoUUN3ME21Mlk5QTR|IN88US=> MU\TRW5ITVJ?
A549 Mn7QS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnjMTWM2OD14LkGyOVU{KM7:TR?= MoPvV2FPT0WU
LS-1034 M1fqN2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MX7JR|UxRTZwMkC3NFYh|ryP M3TxOXNCVkeHUh?=
NB14 MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXzJR|UxRTZwNEO4N|Yh|ryP NFv6flZUSU6JRWK=
NCI-H1299 M{GxcWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmW1TWM2OD14Lk[zNVcyKM7:TR?= M2LI[XNCVkeHUh?=
BT-549 Mnv0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIrLUlJKSzVyPU[uOlY5QDlizszN M4[1bXNCVkeHUh?=
J-RT3-T3-5 M{\VfWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NELrZWlKSzVyPU[uPFY6KM7:TR?= MoO2V2FPT0WU
SW756 Mnn4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUDJR|UxRTZwOUGxO|Yh|ryP MlLmV2FPT0WU
DJM-1 NFu0VmJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmTFTWM2OD14LkmyNFEzKM7:TR?= NF7FW3RUSU6JRWK=
GP5d MXfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEC4XodKSzVyPU[uPVc{QTRizszN MWTTRW5ITVJ?
MOLT-4 NHnydHJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MU\JR|UxRTdwMEKxN|Uh|ryP MkPiV2FPT0WU
NCI-H28 MWfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHPa[|ZKSzVyPUeuNVY1ODVizszN NHm3eXNUSU6JRWK=
MN-60 MXTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUnJR|UxRTdwMkiwPFkh|ryP MlfrV2FPT0WU
RMG-I MkniS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFOxeoJKSzVyPUeuN|kzQTZizszN MUjTRW5ITVJ?
COLO-800 Mln3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHX2VVBKSzVyPUeuOFE1PDZizszN M4DkWnNCVkeHUh?=
DB M{\Jc2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVTjWo1jUUN3ME23MlYyODB3IN88US=> MUfTRW5ITVJ?
Ca-Ski NGHKV2FIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXmwRnc6UUN3ME23MlY1OjV7IN88US=> MXnTRW5ITVJ?
HEL NVrnUnBMT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUTuNIxjUUN3ME23MlcyOjB|IN88US=> NXG2VXlzW0GQR1XS
NH-12 Mle0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MkLWTWM2OD15LkeyPFA5KM7:TR?= NVjHSXFMW0GQR1XS
LB373-MEL-D NVTYNGNFT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{e1[WlEPTB;Nz63Olc4OSEQvF2= NH\Xb|RUSU6JRWK=
SW900 Mn;3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MkX1TWM2OD15LkiyNVIyKM7:TR?= MmOxV2FPT0WU
JVM-3 M{fKSWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWrJR|UxRTdwOEm1PVkh|ryP NVvT[mp7W0GQR1XS
OAW-28 M4nHdGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHvNUXJKSzVyPUeuPVQ2PzhizszN MnLxV2FPT0WU
KURAMOCHI MmHqS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3q4e2lEPTB;Nz65OFgyOSEQvF2= Mo\MV2FPT0WU
BE-13 NF21dlNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWLJR|UxRTdwOUixNVIh|ryP M3vHZXNCVkeHUh?=
VMRC-RCZ NV3pVlhST3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NE\VV|hKSzVyPUiuNFE3QTdizszN MnroV2FPT0WU
NCI-H727 NILZN4tIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MY\JR|UxRThwMUC0NkDPxE1? MXLTRW5ITVJ?
SW1710 MkjXS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYTLSG9pUUN3ME24MlE5PTF3IN88US=> M3vtb3NCVkeHUh?=
D-502MG M3zkR2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXXJR|UxRThwMkmyPFIh|ryP MVjTRW5ITVJ?
NCI-H1993 MofLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWf6bpNFUUN3ME24MlM{PjNzIN88US=> NWfCUWh6W0GQR1XS
SCC-4 MnvmS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M37xWGlEPTB;OD60OFA2QSEQvF2= MXzTRW5ITVJ?
HAL-01 NHzmV3NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mn3wTWM2OD16LkWxPVEh|ryP M2PC[HNCVkeHUh?=
GT3TKB M{mwfGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M33ORmlEPTB;OD62O|k3PCEQvF2= MX3TRW5ITVJ?
SK-OV-3 MlL5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVv3THdEUUN3ME24MlcyOzJ7IN88US=> NUPXWlhJW0GQR1XS
COLO-829 NGHVXWxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXnJR|UxRThwOEC5O|Yh|ryP NFO0ZZNUSU6JRWK=
OCI-AML2 MlSyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3T4[WlEPTB;OD65OVQ5OSEQvF2= NV\6THFoW0GQR1XS
OS-RC-2 NF\tfHVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEfJdItKSzVyPUmuNFIyQSEQvF2= NXzQNWk5W0GQR1XS
BFTC-909 MWHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MY\JR|UxRTlwME[3PVkh|ryP NGHJV4VUSU6JRWK=
EW-11 MmfKS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVLJR|UxRTlwMUe2OVMh|ryP NXnOS4lDW0GQR1XS
HCE-4 NUHVbVk4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWjIUIUyUUN3ME25MlIyPTV6IN88US=> NH7sUW5USU6JRWK=
BALL-1 MVLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWrxWnhpUUN3ME25MlIyQTB5IN88US=> M{HFVXNCVkeHUh?=
SF539 MWXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUHJR|UxRTlwMkO1OlIh|ryP MYjTRW5ITVJ?
CAMA-1 NXrXSZFzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUnzZoRRUUN3ME25MlI5OTJ6IN88US=> MkPwV2FPT0WU
C32 M4XFUGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3SxTWlEPTB;OT6zN|A3PCEQvF2= M4jaeHNCVkeHUh?=
NCI-H1703 MkPPS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlnWTWM2OD17LkO0N|c2KM7:TR?= M4nkenNCVkeHUh?=
NCI-H1650 MYfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVHJR|UxRTlwNkC5OFYh|ryP MWrTRW5ITVJ?
NCI-H1563 NUnrV|lzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVfselA{UUN3ME25Mlc3ODNzIN88US=> MUXTRW5ITVJ?
CAL-85-1 NWDBcm92T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXnMS5ZtUUN3ME25Mlg4Ozh|IN88US=> NHX0[GxUSU6JRWK=
UM-UC-3 MUDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGfVXo1KSzVyPUmuPVUxOyEQvF2= Mmr0V2FPT0WU
BxPC-3 MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Ml62TWM2OD1zMD6wPVczKM7:TR?= MnfQV2FPT0WU
MHH-PREB-1 NES0RnJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NH7WW3FKSzVyPUGwMlE6QTlizszN M{Lo[3NCVkeHUh?=
DEL NXrHW2FPT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3PkU2lEPTB;MUCuN|k1PiEQvF2= NYm3UoMzW0GQR1XS
HuCCT1 NYHs[VRyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NI[3cYFKSzVyPUGwMlYxOzNizszN MYfTRW5ITVJ?
OVCAR-4 MkTSS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Ml[xTWM2OD1zMD64PFM2KM7:TR?= NVH5TItmW0GQR1XS
CAL-72 NF:2NoJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGHYNJpKSzVyPUGwMlk{QTFizszN MoPrV2FPT0WU
HCC1954 NILnSlJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUTJR|UxRTFzLkC3OVQh|ryP Ml3QV2FPT0WU
EFO-21 NFezRVhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmrlTWM2OD1zMT6xNFQ2KM7:TR?= Mmj2V2FPT0WU
FTC-133 NV3US4VKT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmjDTWM2OD1zMT6xOFA4KM7:TR?= M4\1VXNCVkeHUh?=
SK-MEL-24 MVvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVPJR|UxRTFzLkKzOlYh|ryP NUnyfIZHW0GQR1XS
UACC-62 NUj3XHU6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXzJR|UxRTFzLkKzOlgh|ryP NGHYWZRUSU6JRWK=
NCI-H650 NXXuZlJwT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlnSTWM2OD1zMT6yOFE5KM7:TR?= NELDUmJUSU6JRWK=
ALL-PO MkPmS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYTJR|UxRTFzLkK1NVIh|ryP M{LJ[HNCVkeHUh?=
T84 NWrKTJFkT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUHZVYxyUUN3ME2xNU4{QTB5IN88US=> MV7TRW5ITVJ?
IST-MEL1 MnfSS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NH\QSYVKSzVyPUGxMlQ2PTlizszN Mn7aV2FPT0WU
SW626 NYTzdJlFT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3:5UmlEPTB;MUGuOVc2PSEQvF2= M3z2bXNCVkeHUh?=
RPMI-2650 NV;BSpJQT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFfVTnFKSzVyPUGxMlU5QDVizszN MWPTRW5ITVJ?
MC-IXC MmS1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mn[0TWM2OD1zMT62O|I5KM7:TR?= MYnTRW5ITVJ?
HOP-62 MmnQS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWHJR|UxRTFzLk[3OlQh|ryP NVz0cVFHW0GQR1XS
NOS-1 NXLOOnpsT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NH7r[VFKSzVyPUGxMlcyODlizszN M4ewVnNCVkeHUh?=
SW1573 M4XjZWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3\rWWlEPTB;MUGuO|I6PSEQvF2= Mnr1V2FPT0WU
WM-115 M2PmO2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVHEOJFuUUN3ME2xNU44PTh6IN88US=> MXLTRW5ITVJ?
HuO9 NYXCe5g3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmPVTWM2OD1zMT64O|c1KM7:TR?= Ml2zV2FPT0WU
YAPC NELLdWRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MkD0TWM2OD1zMT65NlU6KM7:TR?= MoDKV2FPT0WU
MDA-MB-453 MoPZS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXTEO45jUUN3ME2xNU46PTF3IN88US=> M3fD[nNCVkeHUh?=
NCI-H596 NYDHNmY1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYPkXZpNUUN3ME2xNk4xOzZ7IN88US=> NEDEToJUSU6JRWK=
A172 MmTFS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MU\JR|UxRTF{LkC3PVgh|ryP MYTTRW5ITVJ?
RS4-11 Ml;SS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1zqWWlEPTB;MUKuNVczPSEQvF2= NFrEe5RUSU6JRWK=
HCC1937 NWfhd2Z5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NID2[3pKSzVyPUGyMlc2PjRizszN M16xV3NCVkeHUh?=
SW837 MYPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWnqUJVoUUN3ME2xNk46ODJ6IN88US=> MYjTRW5ITVJ?
NMC-G1 MY\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnnwTWM2OD1zMj65NlM1KM7:TR?= MXjTRW5ITVJ?
PFSK-1 M3v4eGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXrrXZV1UUN3ME2xN{4xPiEQvF2= MmPOV2FPT0WU
DBTRG-05MG MnnES5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWTJR|UxRTF|LkC2N|Ih|ryP NEjoT5pUSU6JRWK=
SK-UT-1 M2nJSWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NV\Xb2UxUUN3ME2xN{4yODh|IN88US=> MX3TRW5ITVJ?
OVCAR-5 NIL1WlVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mn7GTWM2OD1zMz6xOVk{KM7:TR?= M3Lrd3NCVkeHUh?=
8505C NYr6doRTT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2ToWGlEPTB;MUOuNlA3PyEQvF2= NVv2PXg1W0GQR1XS
SK-MEL-1 NHPxW2hIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4myUWlEPTB;MUOuO|E{PSEQvF2= MYfTRW5ITVJ?
LK-2 MnHZS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NG[5WodKSzVyPUGzMlc3OzlizszN NHXVZ45USU6JRWK=
OE33 NHrER3hIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYfUbY5VUUN3ME2xN{44QDZizszN Ml\YV2FPT0WU
Ramos-2G6-4C10 NG[w[|hIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mm\XTWM2OD1zND6wNlAzKM7:TR?= Ml;5V2FPT0WU
EW-13 NYHiXlZtT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEDqZXlKSzVyPUG0MlA{PTJizszN MX3TRW5ITVJ?
NCI-H1793 NV\ZVlZ3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4LST2lEPTB;MUSuNlA5PyEQvF2= NFTYeVBUSU6JRWK=
BHT-101 NHntR5RIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnfTTWM2OD1zND6yOFEh|ryP MWnTRW5ITVJ?
RKO NH3JVmxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVryNXF4UUN3ME2xOE42ODd3IN88US=> NVnYPVROW0GQR1XS
NEC8 NYKxZpV[T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkfXTWM2OD1zND61OFczKM7:TR?= NHzvXGFUSU6JRWK=
PANC-10-05 NGLjdZNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4DFcWlEPTB;MUSuOlI1PyEQvF2= MXPTRW5ITVJ?
NCI-H2030 MnL1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVfJR|UxRTF2Lk[0OFgh|ryP Mnr2V2FPT0WU
C2BBe1 MXLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2f4O2lEPTB;MUSuO|Y1KM7:TR?= MkPaV2FPT0WU
EM-2 NX;n[2FXT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYHUZ2xSUUN3ME2xOE45PTd4IN88US=> MmXVV2FPT0WU
HCC1395 NWD5PWFkT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MX;JR|UxRTF2LkmzN|gh|ryP MnnFV2FPT0WU
A2058 M1uxSWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{XGe2lEPTB;MUWuNFQxQSEQvF2= Mmn4V2FPT0WU
SW1463 MWHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWDQZphwUUN3ME2xOU4xPDh3IN88US=> NYnrb|ZVW0GQR1XS
J82 NVX4Sm9kT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIjBO4pKSzVyPUG1MlA2PyEQvF2= NWmzb3FQW0GQR1XS
CAL-120 NET0WHpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MW\JR|UxRTF3LkG0OFch|ryP MXvTRW5ITVJ?
COLO-824 M4XQOmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NF\LZmtKSzVyPUG1MlE2PzlizszN NYD4RodYW0GQR1XS
LNCaP-Clone-FGC NFPSOWZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHnZc4VKSzVyPUG1MlQzPDhizszN NXyze|VXW0GQR1XS
CP66-MEL NXPsZYVmT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFS1NFJKSzVyPUG1MlQ3QDhizszN M{\lRnNCVkeHUh?=
OC-314 NGm0NJlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mm\XTWM2OD1zNT60O|E1KM7:TR?= NXP2WG92W0GQR1XS
OVCAR-8 MYjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVzJR|UxRTF3Lki4OlEh|ryP MYLTRW5ITVJ?
MFE-280 MonVS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWrQXI04UUN3ME2xOk4xPDh6IN88US=> M4PjNnNCVkeHUh?=
MHH-NB-11 NFXUc|RIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGrWeJVKSzVyPUG2MlA5OzlizszN M2fZS3NCVkeHUh?=
SW1990 NGHNUllIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWPJR|UxRTF4LkG3OVUh|ryP NEHs[|JUSU6JRWK=
U-266 MlX1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2rK[GlEPTB;MU[uNlI6QSEQvF2= M3jIbnNCVkeHUh?=
MFM-223 MYfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEjOR|JKSzVyPUG2MlM6PjVizszN MlXVV2FPT0WU
L-363 Mn\oS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEDXUWFKSzVyPUG2MlQ2PzdizszN NHTXUpVUSU6JRWK=
MCF7 NV3hVppHT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmrrTWM2OD1zNj60O|I{KM7:TR?= NUjYdI5JW0GQR1XS
SK-MEL-3 NWXSW2xmT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkTJTWM2OD1zNj60O|g4KM7:TR?= M3Pxb3NCVkeHUh?=
HH M3XiNWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXHJR|UxRTF4LkWxOlIh|ryP NX3xZolzW0GQR1XS
no-10 MnvYS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4DuZmlEPTB;MU[uOlM1OyEQvF2= Mo\BV2FPT0WU
HuP-T3 MofyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIfTdJRKSzVyPUG2MlY2PzZizszN NUi1SpFsW0GQR1XS
QIMR-WIL NVflVllFT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGi5W45KSzVyPUG2MlcyODVizszN NYfT[Xh{W0GQR1XS
NCI-H1092 NInOSINIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWjkVJZPUUN3ME2xOk45OzF4IN88US=> MWnTRW5ITVJ?
MZ2-MEL MY\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFXKeWhKSzVyPUG2Mlg1ODNizszN NWX5UVZ{W0GQR1XS
ES3 MWPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NIL3bXVKSzVyPUG2MlkyOzRizszN Ml3PV2FPT0WU
COLO-684 MlfqS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NE\J[lhKSzVyPUG2Mlk1PzdizszN NF3ue5dUSU6JRWK=
NCI-H661 M360Umdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGXUN3BKSzVyPUG2Mlk3QTRizszN MXrTRW5ITVJ?
CP50-MEL-B NIfjSHRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGjuOm1KSzVyPUG3MlA{PDNizszN NVK0UFQyW0GQR1XS
NCI-H2405 NWHSS2hDT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHXOdGtKSzVyPUG3MlE6PzRizszN MWjTRW5ITVJ?
U-2-OS M4rFeGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmXvTWM2OD1zNz61N|A4KM7:TR?= MoLOV2FPT0WU
RERF-LC-MS MX\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFX0c5dKSzVyPUG3MlU2ODhizszN MX;TRW5ITVJ?
NCI-H2342 NXmzWHpOT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWTDbIRMUUN3ME2xO{42PTdizszN NF31SpdUSU6JRWK=
ES8 M4GzSWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVHJR|UxRTF5Lk[wPFch|ryP M1TjUHNCVkeHUh?=
MOLT-16 MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoXRTWM2OD1zNz64PVM1KM7:TR?= NVuyN5RWW0GQR1XS
RH-18 NYTtdXZzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1zUVmlEPTB;MUiuNFA{PSEQvF2= Mkj1V2FPT0WU
D-283MED NUPrdGgzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGTLWodKSzVyPUG4MlAxQDhizszN MVvTRW5ITVJ?
RCC10RGB M3LP[mdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{O4VWlEPTB;MUiuNFU2QSEQvF2= M1fkNnNCVkeHUh?=
NCI-H1437 NH;UR|ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlTETWM2OD1zOD6xOlQyKM7:TR?= M{TMRXNCVkeHUh?=
SW982 MVjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXrqTVBiUUN3ME2xPE4zPjdzIN88US=> NEnjXZZUSU6JRWK=
IST-MES1 MVHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUnJR|UxRTF6LkS0Nlgh|ryP Mn\2V2FPT0WU
A704 NVTSSW8{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEfCdVJKSzVyPUG4MlQ4PTNizszN NHzpSGJUSU6JRWK=
ESS-1 NF31[pNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MkPXTWM2OD1zOD61NlA2KM7:TR?= NWTaeI9TW0GQR1XS
SCH NILNfpNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEfUTo5KSzVyPUG4MlY1PTZizszN M4X3eHNCVkeHUh?=
COLO-320-HSR M1XVcmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVroflRpUUN3ME2xPE44PDZizszN M4PMTXNCVkeHUh?=
Mo-T NXXoO5RUT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFTMe4NKSzVyPUG4MlgzODRizszN MYrTRW5ITVJ?
Saos-2 M2naUmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFToT3VKSzVyPUG5MlEyPjJizszN NUTGRW9KW0GQR1XS
SW684 MWnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGfw[o1KSzVyPUG5MlE{OjZizszN NEm4ZnpUSU6JRWK=
KMOE-2 NYDXNWVYT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{ToSmlEPTB;MUmuNlI1OiEQvF2= NXzSbZBmW0GQR1XS
MMAC-SF M{TuVmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUnJR|UxRTF7LkK2NFch|ryP NFjwRWRUSU6JRWK=
JAR MojWS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGXmXpdKSzVyPUG5MlI6QSEQvF2= Ml7yV2FPT0WU
SK-MEL-28 MkfCS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MW\JR|UxRTF7LkOzOlMh|ryP NYW1UXFvW0GQR1XS
KNS-81-FD MXPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEHMOYVKSzVyPUG5MlU1PjhizszN NITwSpZUSU6JRWK=
ES7 NWiyXGRsT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{GzZ2lEPTB;MUmuOlI6OiEQvF2= MmexV2FPT0WU
AsPC-1 NWXiN2lMT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWfKTYE6UUN3ME2xPU43PDdzIN88US=> NHjyXZVUSU6JRWK=
NCI-H1155 MljGS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIXTeZFKSzVyPUG5MlczOzhizszN M2POfnNCVkeHUh?=
KYSE-510 MUTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFP3XYtKSzVyPUG5Mlg4PDhizszN MUDTRW5ITVJ?
ES1 NUnhR3Y5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1P5[WlEPTB;MUmuPVIyOyEQvF2= NGmxPW9USU6JRWK=
PC-3 NV7zRnV2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGnIPIZKSzVyPUG5Mlk3ODRizszN MlvOV2FPT0WU
GCT NFr2OplIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{fxVWlEPTB;MkCuN|AzPiEQvF2= M2TZOnNCVkeHUh?=
KARPAS-299 NEPXN3JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnHzTWM2OD1{MD6zOFIzKM7:TR?= MWXTRW5ITVJ?
DOHH-2 MlzaS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXPrbZJwUUN3ME2yNE42PDZ|IN88US=> NFTrR|NUSU6JRWK=
COLO-741 MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYjRflJxUUN3ME2yNE43PiEQvF2= NULoT2FYW0GQR1XS
NCI-H1395 M3;yNWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWDl[oVsUUN3ME2yNE43Pjl5IN88US=> NVjmWWJEW0GQR1XS
HCC1187 MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4rDUmlEPTB;MkCuOlc{PCEQvF2= M{nDT3NCVkeHUh?=
Becker NYe0WVBqT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHHZSXJKSzVyPUKwMlczODFizszN M2nlNHNCVkeHUh?=
LU-134-A MojaS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHnQN3BKSzVyPUKxMlExOjZizszN M3nabnNCVkeHUh?=
MKN45 MnvFS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Ml63TWM2OD1{MT6xOVUyKM7:TR?= M3ryenNCVkeHUh?=
LC-2-ad M4XhOmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmfQTWM2OD1{MT6yO|I6KM7:TR?= M3TkT3NCVkeHUh?=
EW-24 Mlf2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NG\QdGJKSzVyPUKxMlM6PDVizszN NGn2fWZUSU6JRWK=
SK-N-AS MVHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4T1emlEPTB;MkGuPFI4PiEQvF2= Mo\OV2FPT0WU
NCI-H2052 NYLSNZFKT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIT4foxKSzVyPUKxMlg6PjNizszN Mn;tV2FPT0WU
A4-Fuk MlfvS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlvQTWM2OD1{Mj6xOFE6KM7:TR?= NILHOotUSU6JRWK=
NB10 MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkfqTWM2OD1{Mj6yN|cyKM7:TR?= MoX2V2FPT0WU
CHP-212 MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MV7JR|UxRTJ{LkOyNlIh|ryP MWTTRW5ITVJ?
KM12 MlTVS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXXJR|UxRTJ{LkO1OkDPxE1? M1fVTXNCVkeHUh?=
JEG-3 NYjTZ4VtT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFjFNJpKSzVyPUKyMlM4QCEQvF2= MojNV2FPT0WU
LN-405 M{DhR2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWraZpROUUN3ME2yNk42QTF|IN88US=> NFjmbZdUSU6JRWK=
HCT-15 NIWxfHhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnjyTWM2OD1{Mj63OFQyKM7:TR?= MkXqV2FPT0WU
MLMA MniyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmPkTWM2OD1{Mj63OFch|ryP M{nEVXNCVkeHUh?=
GI-1 Mm\5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWPEPW1NUUN3ME2yNk44PjV6IN88US=> MXPTRW5ITVJ?
RT-112 MXHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MW\JR|UxRTJ{Lki2NVYh|ryP NWf5OXVmW0GQR1XS
MPP-89 M4fZRWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHvqfnNKSzVyPUKyMlg3PjFizszN NFWxVJpUSU6JRWK=
A3-KAW M2\a[Wdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGnkfmJKSzVyPUKzMlExODNizszN NXjtTmFiW0GQR1XS
KALS-1 M1L5Zmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXvvWphJUUN3ME2yN{4yPDF2IN88US=> NHuwS|JUSU6JRWK=
SF126 MYHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYK4ZpFCUUN3ME2yN{43QTJ2IN88US=> M{nhOHNCVkeHUh?=
SiHa NEnHNFFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmHBTWM2OD1{Mz65N|I4KM7:TR?= NH\jPFJUSU6JRWK=
MDA-MB-415 M3fnfGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnzOTWM2OD1{Mz65OFk6KM7:TR?= M2TBdnNCVkeHUh?=
Daoy NWrkTpNyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFzQOmNKSzVyPUK0MlEzPiEQvF2= M{\EOHNCVkeHUh?=
COR-L23 M{LGfmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHTydFdKSzVyPUK0MlE4PjdizszN NX\Fd|hxW0GQR1XS
KG-1 MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnX3TWM2OD1{ND6xPVI5KM7:TR?= MUHTRW5ITVJ?
L-428 MVLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NX3XPHg1UUN3ME2yOE42PzlzIN88US=> NIOxTZlUSU6JRWK=
NCI-H520 NGLYeGxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWjuco1IUUN3ME2yOE45QDZzIN88US=> M2npNHNCVkeHUh?=
COLO-792 NXXGXYhQT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2\DR2lEPTB;MkWuNlc{OiEQvF2= Mnu3V2FPT0WU
NB12 M2P2emdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmO3TWM2OD1{NT6yPVQ4KM7:TR?= MUHTRW5ITVJ?
GAK M160e2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmLxTWM2OD1{NT6yPVY{KM7:TR?= M2D3XHNCVkeHUh?=
SW780 MoPJS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnXMTWM2OD1{NT6zNlY1KM7:TR?= MV3TRW5ITVJ?
GB-1 M3PXeWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4HYOWlEPTB;MkWuOFA3QSEQvF2= NW\w[IN2W0GQR1XS
P12-ICHIKAWA NIrqeIRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHH4NZZKSzVyPUK1MlQ4QDVizszN MXnTRW5ITVJ?
NCI-H1651 MUTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2rUe2lEPTB;MkWuOVk4KM7:TR?= NIS0Z|ZUSU6JRWK=
KE-37 NEnhcGRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYi4NGFSUUN3ME2yOU44OzF3IN88US=> NWrRXZVZW0GQR1XS
CCRF-CEM M4W3TWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGDXTFNKSzVyPUK1Mlk3PyEQvF2= NGXNdnFUSU6JRWK=
SF295 NGHES4FIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYXJR|UxRTJ4LkC0NlUh|ryP NV;UPW9QW0GQR1XS
G-361 MW\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2Dkd2lEPTB;Mk[uNVAzPyEQvF2= MWTTRW5ITVJ?
HOP-92 M1nyRmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MX3JR|UxRTJ4LkGyNlYh|ryP MnnoV2FPT0WU
UMC-11 MnHmS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{XzcGlEPTB;Mk[uOFUyPCEQvF2= NVfrXFRWW0GQR1XS
IST-SL1 Ml\SS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGPnT2VKSzVyPUK2MlY2QTFizszN NWnIOXdQW0GQR1XS
TE-11 Mny5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVfZVHRoUUN3ME2yOk44PzV{IN88US=> NYrydVRCW0GQR1XS
NCI-H1304 M{fle2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGDJNJhKSzVyPUK2MlkyODhizszN NEi4[XpUSU6JRWK=
SJSA-1 NH;ZTIdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mof2TWM2OD1{Nz6wNVc3KM7:TR?= MV3TRW5ITVJ?
BCPAP NY\CWFJ7T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGDjdplKSzVyPUK3MlE{PyEQvF2= MUDTRW5ITVJ?
HTC-C3 M1zm[2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFzufnRKSzVyPUK3MlI2PjFizszN NVnaW|FQW0GQR1XS
EW-16 NF3jeJhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NE\E[XBKSzVyPUK3MlI6PDdizszN MVvTRW5ITVJ?
HT-144 NV30eppkT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MX7JR|UxRTJ5LkSwN|Ih|ryP NV3GSXdOW0GQR1XS
MHH-ES-1 NFXvdIRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3PNcWlEPTB;MkeuOFQ1PyEQvF2= NF36dHRUSU6JRWK=
T98G MVjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFy1XZFKSzVyPUK3MlU5PDZizszN M3T1fnNCVkeHUh?=
RPMI-8866 NWTDTmxKT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYrJR|UxRTJ5Lke1OlIh|ryP M4TI[3NCVkeHUh?=
BEN NXTWO3AyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MULJR|UxRTJ5Lki1NVch|ryP M4ToTHNCVkeHUh?=
MDA-MB-231 MmLjS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFHVd2lKSzVyPUK4MlI4QTVizszN M1raTnNCVkeHUh?=
HuH-7 M3HVVmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mle5TWM2OD1{OD60NFI5KM7:TR?= MoDWV2FPT0WU
SK-N-FI NUXsUYdPT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnHyTWM2OD1{OD60N|Mh|ryP Ml;qV2FPT0WU
AN3-CA NYr6TFBzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4fSeWlEPTB;MkiuOFM6PSEQvF2= M4K5TXNCVkeHUh?=
EGI-1 MkDVS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NH2yOXFKSzVyPUK4MlU6OjhizszN M1rGVXNCVkeHUh?=
697 M3zNVWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWK3fGVrUUN3ME2yPE43OzNzIN88US=> NXzpNHFSW0GQR1XS
TCCSUP MoPjS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVewWI9EUUN3ME2yPE43PDF6IN88US=> MnLpV2FPT0WU
GR-ST MlXuS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3G4eWlEPTB;MkiuOlY6PiEQvF2= M3H4OnNCVkeHUh?=
SK-N-DZ MXLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnvjTWM2OD1{OD62PFg2KM7:TR?= M{fKNHNCVkeHUh?=
MIA-PaCa-2 MYjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHL1PWFKSzVyPUK4Mlc6PTlizszN NF7OeHVUSU6JRWK=
IGR-1 NGXPemRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2DZV2lEPTB;MkiuPFg4PCEQvF2= NH\xW4ZUSU6JRWK=
BFTC-905 MXjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXrJR|UxRTJ7LkK3NFUh|ryP MkXMV2FPT0WU
NCI-H1581 MlPhS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mo\lTWM2OD1{OT6zNVQ2KM7:TR?= M1zxeHNCVkeHUh?=
RD MmTzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3zqSGlEPTB;MkmuOVI{OyEQvF2= MoXKV2FPT0WU
SF268 MYPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkPETWM2OD1{OT61PVMyKM7:TR?= MXHTRW5ITVJ?
SHP-77 NWq3boltT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2W3SWlEPTB;MkmuOlE5OiEQvF2= NIqzbFFUSU6JRWK=
D-566MG NFi1eppIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1zFTGlEPTB;MkmuPVM6OyEQvF2= NIDkRnBUSU6JRWK=
TGBC1TKB M2PQRmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWXoU5hMUUN3ME2zNE4yOjN6IN88US=> NVrTXo1VW0GQR1XS
MEL-HO MlW3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYrOfoI{UUN3ME2zNE4yPDJ|IN88US=> M1\ZWnNCVkeHUh?=
SJRH30 MUHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYDUV2ZHUUN3ME2zNE4zOTB6IN88US=> M4e4NnNCVkeHUh?=
D-336MG NX7ZT|lvT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4j6N2lEPTB;M{CuNlg6OiEQvF2= NXXCZWs3W0GQR1XS
C3A M1PUSmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYWzU5ZLUUN3ME2zNE4zQTJ5IN88US=> NYOwU45[W0GQR1XS
Calu-6 M4Hjdmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVXQVYpJUUN3ME2zNE4zQTZ|IN88US=> MlHFV2FPT0WU
MZ1-PC MVHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{PxZmlEPTB;M{CuN|k{KM7:TR?= M3XqfHNCVkeHUh?=
KYSE-70 M4PWOWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkjvTWM2OD1|MD61NVE1KM7:TR?= MnPSV2FPT0WU
CAPAN-1 MX7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1fmNGlEPTB;M{CuOVE5OSEQvF2= NGHFdpJUSU6JRWK=
DK-MG NFzYNHRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGrD[WhKSzVyPUOwMlU1PTZizszN M3Ln[HNCVkeHUh?=
SK-HEP-1 NXvz[WtjT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGnFOm9KSzVyPUOwMlY{OjZizszN NYXXT2JSW0GQR1XS
MS-1 M3\adWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Ml7STWM2OD1|MD64PFg6KM7:TR?= MY\TRW5ITVJ?
GI-ME-N MW\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoHOTWM2OD1|MT6wOVcyKM7:TR?= M2LONXNCVkeHUh?=
NCI-H510A NGfiZVBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MofSTWM2OD1|MT60NFA3KM7:TR?= MUXTRW5ITVJ?
NB17 M3XhZWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWTJR|UxRTNzLkWxPFUh|ryP NYO2eppPW0GQR1XS
639-V NV7xd3p7T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mnm1TWM2OD1|MT61NlQ{KM7:TR?= NWn1OYoyW0GQR1XS
CAL-51 MV3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NIjUcZhKSzVyPUOxMlU3PjdizszN M1vCVXNCVkeHUh?=
HGC-27 MmHCS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NH\tSWdKSzVyPUOxMlU5PzNizszN M2joT3NCVkeHUh?=
GOTO MX7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXjTZpZGUUN3ME2zNU45PTB4IN88US=> NH7m[GlUSU6JRWK=
ChaGo-K-1 M13xfGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3TqfmlEPTB;M{KuNFA4KM7:TR?= M3vaTnNCVkeHUh?=
RO82-W-1 NXj6cYxKT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NF;TV5FKSzVyPUOyMlE3ODRizszN NUXtOGc4W0GQR1XS
SH-4 MmjkS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NX;rOpBCUUN3ME2zNk4yQDV6IN88US=> NHn6TJpUSU6JRWK=
A204 NWrzU|dUT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYnnenlRUUN3ME2zNk42ODZ7IN88US=> NWXGVJN7W0GQR1XS
DMS-273 MU\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmfBTWM2OD1|Mj61N|IzKM7:TR?= M4HnbHNCVkeHUh?=
KGN MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4jXOmlEPTB;M{KuOlM{KM7:TR?= M3vUVHNCVkeHUh?=
SK-MEL-2 NH61fZFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmDFTWM2OD1|Mj62OVI4KM7:TR?= NYHvdWlGW0GQR1XS
NCI-H2228 MmDhS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NU\lVmpyUUN3ME2zNk43PjB{IN88US=> MVzTRW5ITVJ?
MKN28 Ml7vS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHXkdW1KSzVyPUOyMlc5OzhizszN M1i4dXNCVkeHUh?=
H-EMC-SS Mn;sS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVPJR|UxRTN{Lkm2O|gh|ryP MWDTRW5ITVJ?
ATN-1 NUKxT3M6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NH:y[JlKSzVyPUOzMlE1OTZizszN NFzyempUSU6JRWK=
D-263MG NYPmU5NtT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUDuOmFOUUN3ME2zN{45Ozd6IN88US=> MlrYV2FPT0WU
LU-135 NVnTToRjT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGXlTZBKSzVyPUOzMlg5OjlizszN NH7uRlZUSU6JRWK=
C8166 NGrmWZBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4j2c2lEPTB;M{OuPFg2PCEQvF2= MXLTRW5ITVJ?
T-24 MnKyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUe4[WJHUUN3ME2zOE4xOjB3IN88US=> NY\HRmtUW0GQR1XS
Mewo NUnWT2N7T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MX\JR|UxRTN2LkGzOFkh|ryP MnfSV2FPT0WU
22RV1 M3nDUmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYnJR|UxRTN2LkG3OVQh|ryP NXnRenA3W0GQR1XS
KM-H2 M3\FNWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NW\SXpNMUUN3ME2zOE4yPzd7IN88US=> M4rXe3NCVkeHUh?=
NCI-H2122 NYTBTVZ2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3\MSGlEPTB;M{SuN|Q4OSEQvF2= NYjDeJZZW0GQR1XS
ABC-1 NVzW[4xxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NILoUllKSzVyPUO0MlM3QTNizszN NVzlVmZSW0GQR1XS
NCI-H1355 M4Hqbmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVnnXZBYUUN3ME2zOE4{QDh7IN88US=> NX22Vpg6W0GQR1XS
NOMO-1 M3HSZmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4D0PWlEPTB;M{SuOVcxOyEQvF2= M3nQZnNCVkeHUh?=
MZ7-mel MmDIS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYDRe5RRUUN3ME2zOE43PDh5IN88US=> MXTTRW5ITVJ?
NCI-H810 NVvsfGlIT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHrWNXVKSzVyPUO0MlczPzhizszN MoXPV2FPT0WU
D-392MG M3fqfGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3H6c2lEPTB;M{WuNFU3PSEQvF2= NWrVd4lPW0GQR1XS
LB771-HNC MWXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWq1TI1iUUN3ME2zOU4yPjV6IN88US=> MojXV2FPT0WU
COLO-679 NGjiXYpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NX;zNmNHUUN3ME2zOU4{QDhizszN NX;xdHNEW0GQR1XS
SK-PN-DW MoLjS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MknGTWM2OD1|NT60N|Y6KM7:TR?= M{jvZXNCVkeHUh?=
VA-ES-BJ Mni1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYnxUoJvUUN3ME2zOU41PjR7IN88US=> NFTNb4xUSU6JRWK=
KNS-42 M3H3bGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVLJR|UxRTN3LkW4NlYh|ryP Mom1V2FPT0WU
RVH-421 M4TadWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MU\JR|UxRTN3Lke2OFUh|ryP NUfLPG9rW0GQR1XS
P30-OHK MoTwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1rWPWlEPTB;M{WuPFc2OiEQvF2= NYTHRVNiW0GQR1XS
G-402 NFr6dmJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYL5UIh1UUN3ME2zOU46QDZ5IN88US=> NH;kTmRUSU6JRWK=
S-117 M{jyemdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFvIOpNKSzVyPUO2MlMxODhizszN M3[wXnNCVkeHUh?=
RXF393 NYPhNGtuT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4r5OGlEPTB;M{[uN|c5PSEQvF2= NXPMPYN2W0GQR1XS
LCLC-103H NW\LcJhXT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MX;JR|UxRTN4Lke4NFMh|ryP NG[5PYJUSU6JRWK=
U-118-MG MYXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoW4TWM2OD1|Nj64PFQ4KM7:TR?= NVzzU4N2W0GQR1XS
8-MG-BA M4XQVGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUjJR|UxRTN4Lkm0PFMh|ryP M4WyOnNCVkeHUh?=
MFH-ino MYHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEiySlRKSzVyPUO3MlM{PzFizszN NVu2ZnBxW0GQR1XS
NCI-H23 MnrUS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVfVUGRXUUN3ME2zO{41OTl4IN88US=> NFjISnJUSU6JRWK=
NCI-H446 MXjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXLtdlV7UUN3ME2zO{41QDZ{IN88US=> MUHTRW5ITVJ?
LU-99A M170WWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlXTTWM2OD1|Nz61O|MyKM7:TR?= NVrYfGJEW0GQR1XS
KP-N-YN NI\SPHBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXzRZWczUUN3ME2zO{43OTl3IN88US=> NEXkZ3JUSU6JRWK=
SCC-9 NYTD[YUyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NX;oXIlIUUN3ME2zO{44QDN6IN88US=> Mn\SV2FPT0WU
EFM-19 NITJRmNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mn:wTWM2OD1|Nz63PVY4KM7:TR?= MWDTRW5ITVJ?
A427 Mm\OS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYDoWm96UUN3ME2zO{46OTB5IN88US=> NHrsVlNUSU6JRWK=
LB831-BLC NWD6TVJUT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{P3WWlEPTB;M{iuOlA{QSEQvF2= MnT4V2FPT0WU
HOS MlPMS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWm2fXlnUUN3ME2zPU43Ojd|IN88US=> NVPPU2VqW0GQR1XS
LAN-6 MU\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NIHBclNKSzVyPUSwMlAyOTJizszN MYjTRW5ITVJ?
U251 M3nMd2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVfJR|UxRTRyLkSwOVQh|ryP NVT0N3hRW0GQR1XS
SNU-387 MnzLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFHycolKSzVyPUSwMlQ2PTNizszN M3HxcXNCVkeHUh?=
DMS-79 M4rSUGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NUjocItyUUN3ME20NE42QDh7IN88US=> Mn7sV2FPT0WU
SK-LU-1 M4D2cGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4fYbmlEPTB;NECuOlU3QCEQvF2= MkTzV2FPT0WU
HT MVXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEnTfWdKSzVyPUSwMlY3OzlizszN M13ZOnNCVkeHUh?=
KP-N-YS NETRVlZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NICzOHhKSzVyPUSwMlY4PjhizszN MoHUV2FPT0WU
DMS-114 NIKxNZFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MknvTWM2OD12MD64N|c1KM7:TR?= M4LKRnNCVkeHUh?=
HUTU-80 MWHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXfJR|UxRTRzLkC1Olkh|ryP NIn2c2pUSU6JRWK=
ONS-76 M1nBemdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{mwNWlEPTB;NEGuOFcxQSEQvF2= NU\wT3Z5W0GQR1XS
A673 NWLnTYJFT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWTQcY1lUUN3ME20NU42OTV5IN88US=> M4CzT3NCVkeHUh?=
HPAF-II NVvLOplZT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MX;JR|UxRTRzLk[3NFkh|ryP M13sfnNCVkeHUh?=
UACC-257 MVPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NX3yN217UUN3ME20NU44OzZ7IN88US=> NEH3dopUSU6JRWK=
EW-22 Mn\qS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3H5dGlEPTB;NEGuPFY6PyEQvF2= M3fQbnNCVkeHUh?=
NCI-H1755 MUfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVnJR|UxRTRzLki3NlUh|ryP NFnFdYJUSU6JRWK=
KYSE-150 M4q2Zmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3LXXGlEPTB;NEKuNVc5OiEQvF2= NIrUVJFUSU6JRWK=
CGTH-W-1 NYfpc2RDT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVnJR|UxRTR{LkS5OVUh|ryP M2TPN3NCVkeHUh?=
NB13 MXLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{nBV2lEPTB;NEKuOlIyPyEQvF2= MmDyV2FPT0WU
SW872 M1\iN2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFfsWZpKSzVyPUSyMlY{OzFizszN M17BPHNCVkeHUh?=
KP-4 MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVfSd2JNUUN3ME20Nk45QDN{IN88US=> NXrqW4t{W0GQR1XS
HCC38 MV7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NV7CTlc{UUN3ME20Nk46PjF6IN88US=> M{L3S3NCVkeHUh?=
BB49-HNC M3;NdGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NH7sbWxKSzVyPUSzMlI{PTZizszN M1TCdXNCVkeHUh?=
CAL-62 MWfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFrOOYJKSzVyPUSzMlQxOjhizszN NFWzdoNUSU6JRWK=
NCI-H2029 Ml3qS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mo\PTWM2OD12Mz61OVgyKM7:TR?= MYXTRW5ITVJ?
M14 MnPXS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYXJR|UxRTR2LkGzN|Ih|ryP Mmi2V2FPT0WU
COLO-680N MXrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NX[ycpdFUUN3ME20OE4{OzlizszN M2f3XnNCVkeHUh?=
Hs-578-T NIHBOXJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWjJR|UxRTR3LkCyPVQh|ryP NIDNNllUSU6JRWK=
MSTO-211H MYnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3jiO2lEPTB;NEWuPVQ5OiEQvF2= MVzTRW5ITVJ?
EW-1 NU\SWGNKT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXvJR|UxRTR3Lkm2PFkh|ryP NHHrWHFUSU6JRWK=
SW948 M2HuPWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFOycGtKSzVyPUS2MlQ1PjJizszN NIL6TGJUSU6JRWK=
NCI-H460 MUXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXXJR|UxRTR4LkWyN{DPxE1? NFy0dWhUSU6JRWK=
CAS-1 NHfDbZpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnXZTWM2OD12Nj63O|AyKM7:TR?= M2\FOXNCVkeHUh?=
TGBC11TKB Moe2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NX[2Z48{UUN3ME20O{4yPzd5IN88US=> NXu1R2oyW0GQR1XS
HD-MY-Z M3jvb2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlK1TWM2OD12OD63PFYh|ryP MnfVV2FPT0WU
NCI-H226 NYXDdpdWT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3nsdmlEPTB;NEmuO|c5PSEQvF2= M1m2XHNCVkeHUh?=
PA-1 NWf6O4ZUT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYHJR|UxRTR7LkizN|Uh|ryP NEPR[WZUSU6JRWK=
LB2518-MEL NG\EeFBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIHxfmZKSzVyPUS5Mlg4OjNizszN Mmm5V2FPT0WU
A101D M3\jVGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYTJR|UxRTR7Lkm0NlUh|ryP NXjRbmVwW0GQR1XS
NCI-H2087 MWXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NG[z[GFKSzVyPUS5Mlk3QDJizszN NInMVllUSU6JRWK=

... Click to View More Cell Line Experimental Data

In vivo Daily oral administration of BIBW2992 at 20 mg/kg for 25 days results in dramatic tumor regression with a cumulative treated/control tumor volume ratio (T/C ratio) of 2%. Reduced phosphorylation of EGFR and AKT is confirmed by immunohistochemical staining of tissue sections. Therefore, like lapatinib and neratinib, BIBW2992 is a next generation tyrosine kinase inhibitor (TKI) that inhibits human epidermal growth factor receptor 2 (Her2) and epidermal growth factor receptor (EGFR) kinases irreversibly. BIBW2992 is not only active against EGFR mutations targeted by first generation TKIs like Erlotinib or Gefitinib, but also against those insensitive to these standard therapies. [1]

Protocol

Kinase Assay:

[1]

+ Expand

In vitro kinase activity assays:

The wild type tyrosine kinase domain of the human EGFR as well as that of the EGFR L858R/T790M double mutant are fused to Glutathione-S-transferase (GST), and extracted. Enzyme activity is then assayed in the presence of the inhibitor BIBW2992, serially diluted in 50% DMSO. A random polymer pEY (4:1) is used as substrate and biotinylated pEY (bio-pEY) is added as a tracer substrate. The kinase domain of HER2 is cloned using the baculovirus system and extracted similarly to that of EGFR kinase. Details of assays for EGFR, HER2, SRC, BIRK and VEGFR2 kinase activity are available in Supplementary information.
Cell Research:

[1]

+ Expand
  • Cell lines: NSCLC cells
  • Concentrations: 0-10 μM
  • Incubation Time: 1 hour
  • Method:

    1 × 104 NSCLC cells are transferred into each well of a 96-well plate and cultured overnight in serum-free media for the EGFR phosphorylation assay. After addition of BIBW2992 on the next day, the plates are incubated at 37 °C for 1 hour. EGF-stimulation is done using 100 ng/mL for 10 min at room temperature. Cells are washed with ice cold PBS, extracted with 120 μL HEPEX buffer per well and shaken at room temperature for 1 hour. In all 2 × 104 cells per well is used for the HER2 phosphorylation assay. Streptavidin precoated plates are coated with anti-EGFR-biotin at 1:100 dilution in blocking buffer and c-erb2/HER2 oncoprotein Ab-5(Clone N24)-Biotin. Cell extracts is then transferred to the antibody-coated wells and incubated at room temperature for 1 hour. Extinction is measured at 450 nm.


    (Only for Reference)
Animal Research:

[1]

+ Expand
  • Animal Models: Athymic NMRI-nu/nu female mice
  • Formulation: In 0.5% methocellulose-0.4% polysorbate-80 (Tween 80)
  • Dosages: 20 mg/kg
  • Administration: Oral administration
    (Only for Reference)

Solubility (25°C)

In vitro DMSO 97 mg/mL (199.61 mM)
Ethanol 15 mg/mL (30.86 mM)
Water Insoluble
In vivo Add solvents to the product individually and in order(Data is from Selleck tests instead of citations):
2% DMSO+30% PEG 300+5% Tween 80+ddH2O
For best results, use promptly after mixing.
10mg/mL

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 485.94
Formula

C24H25ClFN5O3

CAS No. 439081-18-2
Storage powder
in solvent
Synonyms N/A

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

  • Mass
    Concentration
    Volume
    Molecular Weight

*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1
    V1
    C2
    V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT03878524 Not yet recruiting Breast Cancer|Prostate Cancer|Pancreatic Cancer|Acute Myelogenous Leukemia OHSU Knight Cancer Institute|Oregon Health and Science University|Prospect Creek Foundation March 14 2019 Phase 1
NCT03878524 Not yet recruiting Breast Cancer|Prostate Cancer|Pancreatic Cancer|Acute Myelogenous Leukemia OHSU Knight Cancer Institute|Oregon Health and Science University|Prospect Creek Foundation March 14 2019 Phase 1
NCT03827070 Recruiting Non Small Cell Lung Cancer Center Trials & Treatment Europe|Center Trials & Treatment March 5 2019 Phase 1
NCT03827070 Recruiting Non Small Cell Lung Cancer Center Trials & Treatment Europe|Center Trials & Treatment March 5 2019 Phase 1
NCT03727724 Active not recruiting Carcinoma Non-Small-Cell Lung The Netherlands Cancer Institute|Boehringer Ingelheim|Merck Serono International SA December 4 2018 Phase 2
NCT03727724 Active not recruiting Carcinoma Non-Small-Cell Lung The Netherlands Cancer Institute|Boehringer Ingelheim|Merck Serono International SA December 4 2018 Phase 2

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

  • * Indicates a Required Field

Frequently Asked Questions

  • Question 1:

    What’s the recommendation about reconstitution of the compound for in vivo animal study?

  • Answer:

    For in vivo experiment of afatinib, we recommend 0.5% methylcellulose/0.2% Tween 80 as vehicle.

EGFR Signaling Pathway Map

EGFR Inhibitors with Unique Features

Related EGFR Products4

Tags: buy Afatinib (BIBW2992) | Afatinib (BIBW2992) supplier | purchase Afatinib (BIBW2992) | Afatinib (BIBW2992) cost | Afatinib (BIBW2992) manufacturer | order Afatinib (BIBW2992) | Afatinib (BIBW2992) distributor
×
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID