Afatinib (BIBW2992)

Catalog No.S1011

Afatinib (BIBW2992) Chemical Structure

Molecular Weight(MW): 485.94

Afatinib (BIBW2992) inhibits EGFR/ErbB irreversibly in vitro with IC50 of 0.5, 0.4, 10, 14, 1 nM for EGFRwt, EGFR L858R , EGFR L858R/T790M ErbB2 (HER2) and ErbB4 (HER4), respectively.

Size Price Stock Quantity  
In DMSO USD 240 In stock
USD 120 In stock
USD 210 In stock
USD 570 In stock
Bulk Discount

Free Overnight Delivery on orders over $ 500
Next day delivery by 10:00 a.m. Order now.

Cited by 74 Publications

Purity & Quality Control

Choose Selective EGFR Inhibitors

Biological Activity

Description Afatinib (BIBW2992) inhibits EGFR/ErbB irreversibly in vitro with IC50 of 0.5, 0.4, 10, 14, 1 nM for EGFRwt, EGFR L858R , EGFR L858R/T790M ErbB2 (HER2) and ErbB4 (HER4), respectively.
Targets
EGFR (L858R) [1]
(Cell-free assay)
EGFR (wt) [1]
(Cell-free assay)
ErbB4 [2]
(Cell-free assay)
EGFR (L858R/T790M) [1]
(Cell-free assay)
HER2 [1]
(Cell-free assay)
0.4 nM 0.5 nM 1 nM 10 nM 14 nM
In vitro

BIBW2992 shows potent activity against both wild-type and mutant forms of EGFR and HER2. It is similar to Gefitinib in potency against L858R EGFR, but about 100-fold more active against the Gefitinib resistant L858R-T790M EGFR double mutant. BIBW2992 exhibits potent effects on both EGFR and HER2 phosphorylation in vivo. It compares favorably to reference compounds (such as Lapatinib et al.) in all cell types tested, such as human epidermoid carcinoma cell line A431 expressing wt EGFR, murine NIH-3T3 cells transfected with wt HER2, as well as breast cancer cell line BT-474 and gastric cancer cell line NCI-N87, which express endogenous HER2. [1]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
HDLM-2 MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2jtOmlEPTB;MD6wNFU4OiEQvF2= MVjTRW5ITVJ?
KASUMI-1 MnnmS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NF7HR5pKSzVyPUCuNFA6OTFizszN NVO4e2ZoW0GQR1XS
HCC2218 M{i1S2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUnJR|UxRTBwMEC5PFch|ryP MnraV2FPT0WU
KARPAS-45 MoTmS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mn7FTWM2OD1yLkCxOlcyKM7:TR?= MnvmV2FPT0WU
HSC-4 NVL4UmFqT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUHJcZdSUUN3ME2wMlAyPzR6IN88US=> NEDvS2NUSU6JRWK=
CHL-1 MX;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M33UUGlEPTB;MD6wNVg{QSEQvF2= M2L2[XNCVkeHUh?=
KY821 MkLLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mm\RTWM2OD1yLkCyNFYh|ryP MX;TRW5ITVJ?
NCI-N87 NYSwO3R[T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHPSeFNKSzVyPUCuNFI4PzNizszN MWTTRW5ITVJ?
DOK M2K2OGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2fSdWlEPTB;MD6wN|E6PCEQvF2= M3LGSHNCVkeHUh?=
DSH1 NF7GWldIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlrsTWM2OD1yLkCzN|E1KM7:TR?= Mm[1V2FPT0WU
MDA-MB-175-VII Mle2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{nnSGlEPTB;MD6wN|QyPiEQvF2= MWrTRW5ITVJ?
NCI-H2170 MWPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NV2yNZM3UUN3ME2wMlA{PzJ6IN88US=> NWTLPI46W0GQR1XS
BT-474 MV7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4rTNGlEPTB;MD6wOFk5PiEQvF2= MoXQV2FPT0WU
EFO-27 MlvoS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmrHTWM2OD1yLkC1NVgzKM7:TR?= NIPsR|ZUSU6JRWK=
NCI-H720 NXTsPWd6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYPCR4FZUUN3ME2wMlA2OzJ3IN88US=> NWTUOZFCW0GQR1XS
PC-14 M1PrW2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIjGenJKSzVyPUCuNFU3PjhizszN NIPrfHNUSU6JRWK=
EC-GI-10 NV22VopoT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYK2emVNUUN3ME2wMlA2QTF{IN88US=> MWTTRW5ITVJ?
KYSE-450 NHLNeVVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NF;yV|lKSzVyPUCuNFU6PzhizszN MYfTRW5ITVJ?
BPH-1 MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3G2VWlEPTB;MD6wOVk5QCEQvF2= MlzEV2FPT0WU
NCI-H292 NVTRdYhoT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4e5R2lEPTB;MD6wOlA6KM7:TR?= M{fKcHNCVkeHUh?=
H9 NX3Le4JST3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVLtVVFZUUN3ME2wMlA4OTN{IN88US=> M{nNc3NCVkeHUh?=
NCI-H526 NIe5[mRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXqxUId1UUN3ME2wMlA4QDJ|IN88US=> MVXTRW5ITVJ?
NCI-H1623 MmP0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3\OTWlEPTB;MD6wPFAzPSEQvF2= MlnZV2FPT0WU
KYSE-140 M1Psdmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWjJR|UxRTBwMEizN{DPxE1? NGXZeGdUSU6JRWK=
Ca9-22 NVvuRpM3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVnVR5dOUUN3ME2wMlA5OzV|IN88US=> NGXMR4JUSU6JRWK=
AU565 NEXIbGNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2O2N2lEPTB;MD6wPFUxPCEQvF2= NWmyTXFOW0GQR1XS
ZR-75-30 M1KwNWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{H5UGlEPTB;MD6wPVU1PSEQvF2= MkHyV2FPT0WU
NCI-H1770 MlzxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{OzfGlEPTB;MD6xNFI5KM7:TR?= Ml;zV2FPT0WU
LB2241-RCC M1HTVmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFzOZ|JKSzVyPUCuNVA5QDRizszN MUPTRW5ITVJ?
CAL-39 MmnkS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NV;OZnRpUUN3ME2wMlEyPzl{IN88US=> NXvlfYJuW0GQR1XS
UACC-893 MnziS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NILy[pRKSzVyPUCuNVE5QDVizszN MlfKV2FPT0WU
LU-65 NG\1VoNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MkKxTWM2OD1yLkGyOlM{KM7:TR?= NYnVb2hSW0GQR1XS
HN NFzofXJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGDYeFNKSzVyPUCuNVMxPzdizszN MnfuV2FPT0WU
TI-73 NY\I[|JOT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MX3JR|UxRTBwMUS3NVUh|ryP M3LlfnNCVkeHUh?=
KU812 MVXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGTOdmtKSzVyPUCuNVU1PTZizszN M3nL[HNCVkeHUh?=
SW13 MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NX72cXQ4UUN3ME2wMlE3OjF4IN88US=> M3jEeXNCVkeHUh?=
BB30-HNC MUXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NF\w[3NKSzVyPUCuNVY2PzZizszN NGnSS3dUSU6JRWK=
HSC-2 MU\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYXpUolLUUN3ME2wMlE3QDN5IN88US=> M4LXXnNCVkeHUh?=
BV-173 NX61fW4xT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4Gxb2lEPTB;MD6xO|U6PiEQvF2= NFjvSZFUSU6JRWK=
CAL-27 NHO1RXFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NULwN2FCUUN3ME2wMlE4PjN4IN88US=> M2TRVXNCVkeHUh?=
SBC-1 NGrZfGRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWnDcGZMUUN3ME2wMlE5QTV7IN88US=> Ml\zV2FPT0WU
CAL-33 M3fYRWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NH:2emNKSzVyPUCuNlAyQDRizszN M4j1d3NCVkeHUh?=
NCI-H209 M4n5Umdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWLJR|UxRTBwMkC0OkDPxE1? M4GwNHNCVkeHUh?=
COR-L105 M2nucGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGnMWoNKSzVyPUCuNlExQDRizszN MmD5V2FPT0WU
HSC-3 NXLTNHV4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXXJR|UxRTBwMkGxPVgh|ryP M2PkT3NCVkeHUh?=
NCI-H69 NFO1N2ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHfBW4ZKSzVyPUCuNlE1PTFizszN M1XE[HNCVkeHUh?=
MOLT-13 MV;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGT2R2tKSzVyPUCuNlM6PzVizszN MmSxV2FPT0WU
ML-2 NXnHNJd7T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWrF[3Z5UUN3ME2wMlI1QDB{IN88US=> M1P5[XNCVkeHUh?=
IGROV-1 NIKzUnlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEf0OVBKSzVyPUCuNlU6PTJizszN MlnMV2FPT0WU
TK10 MofSS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYnsNHpRUUN3ME2wMlI3PzN6IN88US=> M3z6TnNCVkeHUh?=
EoL-1-cell M4LTdGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVvPVVJWUUN3ME2wMlI3QDl{IN88US=> NHjkS5NUSU6JRWK=
HO-1-N-1 MlvZS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFK2eWRKSzVyPUCuNlc5PTNizszN MlXHV2FPT0WU
BHY Mk\4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3PvZmlEPTB;MD6yPFY2PSEQvF2= NYXC[JpWW0GQR1XS
LU-139 MojyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlHCTWM2OD1yLkOwOVEh|ryP NIXNZVJUSU6JRWK=
23132-87 NYSwVWwxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlXHTWM2OD1yLkOxPVI{KM7:TR?= M{\Y[nNCVkeHUh?=
ACHN M3PpfWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGDsW4RKSzVyPUCuN|E6QTRizszN MnP1V2FPT0WU
DoTc2-4510 M{Hm[mdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFzl[2JKSzVyPUCuN|IzOTlizszN NWPaZ4RFW0GQR1XS
BB65-RCC NULRRnVST3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGP1bYhKSzVyPUCuN|Q2QTNizszN MmD0V2FPT0WU
HLE MVXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NILIcJBKSzVyPUCuN|UxPDZizszN Mk\mV2FPT0WU
HCC1419 NIjYZoZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MkfTTWM2OD1yLkO2OFA5KM7:TR?= NEPsRWpUSU6JRWK=
A388 MUTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{HuXWlEPTB;MD6zOlg2PyEQvF2= MnjoV2FPT0WU
NUGC-3 MV3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXv3OY1DUUN3ME2wMlM5Ozd|IN88US=> NVvsRnRwW0GQR1XS
KYSE-180 NVPJU3gxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2DmNWlEPTB;MD6zPVA5QSEQvF2= NEfmdXZUSU6JRWK=
TE-6 NGnzbYtIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVfEWYhpUUN3ME2wMlQxOjR4IN88US=> NV7UTYJvW0GQR1XS
A498 M1jac2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXPQTnE{UUN3ME2wMlQxPjd2IN88US=> NILGNIJUSU6JRWK=
NCI-H1648 MoO0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXm2Wnl4UUN3ME2wMlQ1OTh{IN88US=> NGXhPZdUSU6JRWK=
DU-145 NGLBUmJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFHkRZpKSzVyPUCuOFQ5OzNizszN MoG2V2FPT0WU
CW-2 MnK5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmSxTWM2OD1yLkS2PVE1KM7:TR?= M{\DcnNCVkeHUh?=
A431 NGXVbm5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUnJR|UxRTBwNEiyN|Mh|ryP NUDhUGpNW0GQR1XS
SAS MlP4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mkn5TWM2OD1yLkS4N|k5KM7:TR?= NEe2No1USU6JRWK=
NCI-H2126 MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkfTTWM2OD1yLkWxPVI3KM7:TR?= M{PNU3NCVkeHUh?=
NCI-H358 NYHrdIl4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlzZTWM2OD1yLkWzNlEh|ryP NV7lUGZjW0GQR1XS
FADU NYO2VZRYT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEntPHVKSzVyPUCuOVQ1ODRizszN MY\TRW5ITVJ?
ACN NILNOJlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1rMVWlEPTB;MD61OVA6PCEQvF2= M1z4VnNCVkeHUh?=
HCC70 MXjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NUjQNW9[UUN3ME2wMlU4PjZzIN88US=> MXfTRW5ITVJ?
NCI-H1838 M4TqcGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIjMZ4dKSzVyPUCuOlAzQTlizszN NUm5c3JLW0GQR1XS
CAL-54 MYPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NV\WXWo6UUN3ME2wMlYyPjJzIN88US=> Mn\iV2FPT0WU
NCI-H1975 NGTXVIRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{H3TmlEPTB;MD62NVczQCEQvF2= NWXBR4pEW0GQR1XS
COR-L88 M3O2Omdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MojKTWM2OD1yLk[0NVE{KM7:TR?= M3v5OnNCVkeHUh?=
CTV-1 NWDofFVyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MojMTWM2OD1yLk[0N|kzKM7:TR?= Mlq2V2FPT0WU
EW-18 M1vj[Gdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NV\iRoFnUUN3ME2wMlY5Pjl6IN88US=> MXzTRW5ITVJ?
HCC1806 MYnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEjGdmZKSzVyPUCuOlk3PjZizszN MlvSV2FPT0WU
HuP-T4 NXTyNpNET3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MW\JR|UxRTBwNkm3OkDPxE1? MYrTRW5ITVJ?
MDA-MB-361 NEfhflhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MW\JR|UxRTBwN{K2OlIh|ryP M{XUSXNCVkeHUh?=
NCI-H1573 MYDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NV7KT2REUUN3ME2wMlc{PjNizszN MVjTRW5ITVJ?
KU-19-19 M4fGN2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWjiZWVDUUN3ME2wMlc4PDZ2IN88US=> M4\KXHNCVkeHUh?=
COLO-678 MXfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1zxSGlEPTB;MD64NFg{PCEQvF2= NEXQV5lUSU6JRWK=
C-33-A NXnXXFZxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYnSfHZpUUN3ME2wMlgyOjl5IN88US=> Ml\BV2FPT0WU
Calu-3 Mn7nS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXjBdZpUUUN3ME2wMlgyPDN2IN88US=> MYrTRW5ITVJ?
AGS M1rFcWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlSxTWM2OD1yLkizOlQ5KM7:TR?= M3;5UnNCVkeHUh?=
SCC-25 MlTCS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEThfWpKSzVyPUCuPFQyPzFizszN NWjhV2RrW0GQR1XS
JVM-2 MXXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4jhXmlEPTB;MD64PFI6QSEQvF2= MluzV2FPT0WU
HCE-T MWDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoP4TWM2OD1yLki4OFI5KM7:TR?= NYjEdJl5W0GQR1XS
ES4 MoK2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MX3JR|UxRTBwOUe4N|Yh|ryP NYjIb4lRW0GQR1XS
EKVX MYXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWfBZnc4UUN3ME2xMlAyODZ2IN88US=> MU\TRW5ITVJ?
D-542MG NILEeYNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYrzTmtsUUN3ME2xMlAyODZ2IN88US=> NUD4bJpHW0GQR1XS
SW1116 NWTkWpA6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlLJTWM2OD1zLkCxNlg4KM7:TR?= MX;TRW5ITVJ?
5637 NWPKSXVFT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{fTeGlEPTB;MT6wNVUyKM7:TR?= M{jTWHNCVkeHUh?=
HT-1376 NF;MSXJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVrJR|UxRTFwMEG1NVMh|ryP MXLTRW5ITVJ?
NB69 NFjKcGRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{DicmlEPTB;MT6wNlk1PSEQvF2= MofHV2FPT0WU
YKG-1 NVHKNXRsT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MU\JR|UxRTFwMEW0NVkh|ryP Ml2zV2FPT0WU
EW-3 NHOzTWFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MoHhTWM2OD1zLkC3PFg{KM7:TR?= NUDYb4htW0GQR1XS
GCIY M4TUUWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIr5VpNKSzVyPUGuNFgyODRizszN MXrTRW5ITVJ?
SK-MES-1 MnrlS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYG3Rm5WUUN3ME2xMlEyPDh5IN88US=> MlWwV2FPT0WU
PANC-08-13 MnjhS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1jTcmlEPTB;MT6xOlQyPiEQvF2= MV7TRW5ITVJ?
SK-NEP-1 MkKwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MULJR|UxRTFwMUe1NVMh|ryP MWXTRW5ITVJ?
SW954 M4LueGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkPXTWM2OD1zLkKwNlE1KM7:TR?= MVPTRW5ITVJ?
NCI-SNU-5 NXrwb5NnT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NF7U[GtKSzVyPUGuNlM6KM7:TR?= NEPqWmdUSU6JRWK=
SW48 M3fsOmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYnJNlllUUN3ME2xMlI2PDN{IN88US=> M3j4TXNCVkeHUh?=
HT-3 NUT4bpE4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkHDTWM2OD1zLkK4O|U{KM7:TR?= MoXzV2FPT0WU
ETK-1 NHHoTHFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mkj2TWM2OD1zLkO3OFU3KM7:TR?= MnWwV2FPT0WU
SCC-15 NHjafIFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUjYS3lzUUN3ME2xMlM6PDVzIN88US=> NWD5UZZxW0GQR1XS
DU-4475 MnjBS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlzXTWM2OD1zLkSwNVIyKM7:TR?= NGSxR25USU6JRWK=
NB5 NEO1bIxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{jIcmlEPTB;MT60NVMyPyEQvF2= NHXMPHZUSU6JRWK=
CFPAC-1 MXHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVq2emNTUUN3ME2xMlQzPDl|IN88US=> M4HWbHNCVkeHUh?=
NCI-H630 M13xR2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mnj0TWM2OD1zLkS1OVgzKM7:TR?= NHXr[G1USU6JRWK=
NCI-H82 NGTS[2FIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3zwXGlEPTB;MT61OFAxPiEQvF2= NXXEOlk2W0GQR1XS
ECC10 NIn4W21Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1jCU2lEPTB;MT61OVM3QSEQvF2= Mlv5V2FPT0WU
K5 MYHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnTZTWM2OD1zLkW4N|U4KM7:TR?= MYfTRW5ITVJ?
ME-180 NXXPRpdNT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYTJR|UxRTFwNkGwPVYh|ryP MYfTRW5ITVJ?
KYSE-410 MonuS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NW\jZZl1UUN3ME2xMlY2Pjd{IN88US=> MXXTRW5ITVJ?
G-401 NUTqSG1xT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIP4PYdKSzVyPUGuOlc1OTNizszN NFPSRZBUSU6JRWK=
TGBC24TKB MojWS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NF;aOFRKSzVyPUGuOlgzOyEQvF2= M1\NPHNCVkeHUh?=
Detroit562 NVrQOVdTT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlS4TWM2OD1zLkewNVUzKM7:TR?= NIjSV5VUSU6JRWK=
OE19 MmrDS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3fIPGlEPTB;MT63NVUyOiEQvF2= MnzVV2FPT0WU
CAKI-1 NFzNSpFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXPJR|UxRTFwN{iyNVEh|ryP M4e5bnNCVkeHUh?=
TE-12 NHXDSHFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFrqc4tKSzVyPUGuPFA1OTRizszN NUXY[pRQW0GQR1XS
NCI-H1666 MW\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoXUTWM2OD1zLkiwPVQ5KM7:TR?= NFjKXJhUSU6JRWK=
TE-1 NUn5VFJGT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnPRTWM2OD1zLkixOFc2KM7:TR?= MoLuV2FPT0WU
CAL-12T NGXOVFNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NID1c|JKSzVyPUGuPFg6PDVizszN M3TBVXNCVkeHUh?=
TE-8 NH\CT2ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYTaNXdsUUN3ME2xMlkyOzd5IN88US=> MUfTRW5ITVJ?
KYSE-270 M{exXGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXTSUXRuUUN3ME2yMlAzPzN{IN88US=> MVjTRW5ITVJ?
GMS-10 M2fKbWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnnLTWM2OD1{LkCzOVE4KM7:TR?= MY\TRW5ITVJ?
A2780 M4HnTmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWP4VVZXUUN3ME2yMlA3Ojl2IN88US=> MmDXV2FPT0WU
OMC-1 NGrMWHZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXjNR4NJUUN3ME2yMlA5OTZ7IN88US=> NIDOOJFUSU6JRWK=
LoVo M2LF[mdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWXJR|UxRTJwMUC3PVch|ryP NW\TTYFKW0GQR1XS
PANC-03-27 MkfLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUXJR|UxRTJwMU[2N|Eh|ryP NHvjZnRUSU6JRWK=
MDA-MB-157 NYPuNopVT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{nRc2lEPTB;Mj6yNVgzQCEQvF2= MnLyV2FPT0WU
CaR-1 NVPOO5hbT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGjp[JVKSzVyPUKuNlgzQDFizszN MWLTRW5ITVJ?
769-P MVrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHfmNndKSzVyPUKuNlkxOzdizszN MoHVV2FPT0WU
NB7 MYfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXHYU5hxUUN3ME2yMlI6Pjd4IN88US=> Mmj6V2FPT0WU
MKN7 M2fOfWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnHuTWM2OD1{LkO1N|M2KM7:TR?= MVLTRW5ITVJ?
NCI-H1048 M2fKcWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mkn6TWM2OD1{LkS5NVU5KM7:TR?= NGrK[mVUSU6JRWK=
RCM-1 NIXDfVhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1j4PWlEPTB;Mj61Nlk{QCEQvF2= NEjucHRUSU6JRWK=
HT55 NUPmSXZsT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoLyTWM2OD1{LkW3N|gh|ryP NV;QZ4hVW0GQR1XS
HCC1569 M37rZ2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGLLcJlKSzVyPUKuOVgzQTdizszN NWLOPJlyW0GQR1XS
LXF-289 MnX2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXzJR|UxRTJwNkO1OlUh|ryP NULqUGRLW0GQR1XS
OVCAR-3 MUPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWrTNYc3UUN3ME2yMlY4OTZ5IN88US=> M4nLR3NCVkeHUh?=
TE-10 NVPIdYpsT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnvLTWM2OD1{Lk[4NFc5KM7:TR?= MkjCV2FPT0WU
SNU-C2B NFfNSolIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmfITWM2OD1{Lk[4OlE3KM7:TR?= NVPke2hPW0GQR1XS
LB1047-RCC MYnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3r6SGlEPTB;Mj63OFg5QCEQvF2= NEC0[Y1USU6JRWK=
SN12C NF3Lc|FIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mlm1TWM2OD1{LkmxPVY1KM7:TR?= M1S2SHNCVkeHUh?=
786-0 MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MorETWM2OD1|LkC2OFA5KM7:TR?= MXnTRW5ITVJ?
HT-29 M2TnRWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NUDkZYRoUUN3ME2zMlA4OzB7IN88US=> NXrsO45JW0GQR1XS
RPMI-7951 MXLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWTJR|UxRTNwMEe1PUDPxE1? MnLDV2FPT0WU
NBsusSR MoDMS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYHJR|UxRTNwMUiyOVQh|ryP MmXMV2FPT0WU
NKM-1 NXHncnFpT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mmm2TWM2OD1|LkG4O|Q1KM7:TR?= NULtbnZJW0GQR1XS
Capan-2 M33uTmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHXL[29KSzVyPUOuOFY5PzVizszN MYLTRW5ITVJ?
MKN1 M3L0Xmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWHJR|UxRTNwNEexNFgh|ryP MXnTRW5ITVJ?
OAW-42 MXHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVjZUpEzUUN3ME2zMlUxODJ4IN88US=> NYm3VlJEW0GQR1XS
SKG-IIIa NFHCTG1Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnXtTWM2OD1|LkWyNlM4KM7:TR?= MXnTRW5ITVJ?
no-11 M3PQcGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIKzSZZKSzVyPUOuOVM2PjRizszN NHjTZYFUSU6JRWK=
NY NVWwRWFnT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2jUNWlEPTB;Mz61N|Y2PSEQvF2= NFPCTZZUSU6JRWK=
HEC-1 MoT4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVTJR|UxRTNwNUi5OUDPxE1? MVnTRW5ITVJ?
NCI-H441 M2fjTWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NV7KOGJ{UUN3ME2zMlU6QDRzIN88US=> MXnTRW5ITVJ?
NCI-H2009 Mlm4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoH2TWM2OD1|Lk[xNlE3KM7:TR?= NEfXXWxUSU6JRWK=
T47D M1S3TGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Ml\MTWM2OD1|Lk[yNlE4KM7:TR?= NXHGR4d1W0GQR1XS
SNU-449 MV;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVfJR|UxRTNwNkW4NlYh|ryP MV\TRW5ITVJ?
NCI-SNU-1 MWHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NG\uR2JKSzVyPUOuOlk4OzVizszN MXzTRW5ITVJ?
BT-20 MULHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NF3zVGVKSzVyPUOuOlk4QTVizszN MYHTRW5ITVJ?
LS-123 NUjjWFF2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXTHbHZZUUN3ME2zMlc1Ojh2IN88US=> M3m1R3NCVkeHUh?=
8305C MkPsS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYLidJFvUUN3ME2zMlc2QTFzIN88US=> M13yW3NCVkeHUh?=
OCUB-M M1SwPWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIrtb2xKSzVyPUOuO|YyQDdizszN NVm4VmlYW0GQR1XS
KOSC-2 NELSdWNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXrJR|UxRTNwOEO0OVEh|ryP MUTTRW5ITVJ?
NCI-H1693 NG\RcYJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYPJR|UxRTNwOESxPFEh|ryP NGrVTVdUSU6JRWK=
TE-9 M{\rZ2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYfJR|UxRTNwOESzPFIh|ryP MkHRV2FPT0WU
MV-4-11 NV:xRnIxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1vCemlEPTB;Mz64O|k6PCEQvF2= M1\QTnNCVkeHUh?=
GAMG NUixXmw3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVnJR|UxRTNwOUGzNVQh|ryP MkfvV2FPT0WU
KNS-62 NYXvcmhHT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MofzTWM2OD1|Lkm0O|MyKM7:TR?= MoD1V2FPT0WU
MC116 MYTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkX6TWM2OD1|Lkm1OFg6KM7:TR?= NEL1eXBUSU6JRWK=
647-V NVrFUGJJT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlrMTWM2OD1|Lkm4OFUzKM7:TR?= MWjTRW5ITVJ?
U-87-MG NU\UUG1vT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnLCTWM2OD12LkGwOFgyKM7:TR?= MVjTRW5ITVJ?
RPMI-8226 MVjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHHpclNKSzVyPUSuNVE3OzFizszN MXHTRW5ITVJ?
SW1417 NHzYUIxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGDyWYxKSzVyPUSuNVIyPDdizszN MX3TRW5ITVJ?
LAMA-84 MmD4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnXBTWM2OD12LkG3NFIh|ryP M2CyVHNCVkeHUh?=
LS-513 NYDnUZYyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYO5Z3VIUUN3ME20MlMyOjF5IN88US=> MkHvV2FPT0WU
KLE MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NUjpSm1wUUN3ME20MlQxQDF7IN88US=> NFzIdnBUSU6JRWK=
HCT-116 NGXJOYdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUfmWIhGUUN3ME20MlQyODB5IN88US=> MVLTRW5ITVJ?
EPLC-272H MXXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Ml\HTWM2OD12LkSxOVM{KM7:TR?= NHnXcoRUSU6JRWK=
KS-1 NYDV[4RkT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVX0epdlUUN3ME20MlUxQDh7IN88US=> M{XTZXNCVkeHUh?=
HT-1197 NEPRe4VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHv5codKSzVyPUSuOVI3PjlizszN MoXwV2FPT0WU
LCLC-97TM1 MlO3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXTJR|UxRTRwNUO2PFYh|ryP M1jYbHNCVkeHUh?=
ES5 MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUDJR|UxRTRwOEO3NlMh|ryP MUXTRW5ITVJ?
CTB-1 NX3DbJY3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGrNZpBKSzVyPUSuPFQ5QCEQvF2= NGPVO2xUSU6JRWK=
HL-60 NXPIO|YzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXizT|dmUUN3ME20Mlg3PjFzIN88US=> MW\TRW5ITVJ?
VM-CUB-1 MXXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnfKTWM2OD12Lki2PFE6KM7:TR?= M3rqbnNCVkeHUh?=
MEG-01 M{GxUGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXjJR|UxRTRwOUm0NFMh|ryP NIC3WWhUSU6JRWK=
KYSE-520 NHLENGhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2PTPWlEPTB;NT6yNFg{QSEQvF2= NFP5eIhUSU6JRWK=
HuO-3N1 M1m4Wmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4H6WGlEPTB;NT6yOFA1OyEQvF2= NHz4b5hUSU6JRWK=
SW620 MXTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHjHS2xKSzVyPUWuNlQ6PjRizszN NVvyPHVTW0GQR1XS
U031 NEXEeIhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmC1TWM2OD13LkK1OFI1KM7:TR?= MlruV2FPT0WU
TE-5 MUTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWHJR|UxRTVwNEC4OUDPxE1? M2HIe3NCVkeHUh?=
NCI-H747 NFPvSG1Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NG\n[VdKSzVyPUWuOFI1PzJizszN Ml:wV2FPT0WU
MG-63 M4\lO2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYLJR|UxRTVwNEi3OlIh|ryP Mk\WV2FPT0WU
HC-1 NF3RfplIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWrxbFR2UUN3ME21MlUyQDN7IN88US=> MnWzV2FPT0WU
HCC2998 MoPYS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWi2SnNGUUN3ME21MlUzPjF3IN88US=> NInJbpJUSU6JRWK=
NTERA-S-cl-D1 MXTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MknYTWM2OD13LkW0OVM4KM7:TR?= M2ezenNCVkeHUh?=
KINGS-1 NFzHeotIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NV3Z[2oyUUN3ME21MlYxQTR2IN88US=> MW\TRW5ITVJ?
D-423MG M4HkVmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4P3WmlEPTB;NT62NVcxPSEQvF2= NXmzTWVMW0GQR1XS
SW962 NFfKbIJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4fZU2lEPTB;NT62NlA{OiEQvF2= MoLXV2FPT0WU
LOXIMVI NYqxd4wxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlTUTWM2OD13Lk[zPFc{KM7:TR?= MU\TRW5ITVJ?
LS-411N NEKxfmJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYnJR|UxRTVwN{m0OFEh|ryP MUfTRW5ITVJ?
NCI-H2291 MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYfJR|UxRTVwOUi5OFMh|ryP M3LnOHNCVkeHUh?=
A549 NX;KNm5nT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2HzcWlEPTB;Nj6xNlU2OyEQvF2= NGnyUFFUSU6JRWK=
LS-1034 NXv2[WtNT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGXHcJZKSzVyPU[uNlA4ODZizszN M3LUU3NCVkeHUh?=
NB14 MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWnJR|UxRTZwNEO4N|Yh|ryP NXixTpdNW0GQR1XS
NCI-H1299 M135d2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M133R2lEPTB;Nj62N|E4OSEQvF2= NFvvOoZUSU6JRWK=
BT-549 MlrWS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{jmOWlEPTB;Nj62Olg5QSEQvF2= M{DQc3NCVkeHUh?=
J-RT3-T3-5 Ml7TS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVzqcop5UUN3ME22Mlg3QSEQvF2= NGjWWHpUSU6JRWK=
SW756 MXvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGjTXIlKSzVyPU[uPVEyPzZizszN M4TuUHNCVkeHUh?=
DJM-1 MYDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVHnW4R4UUN3ME22MlkzODF{IN88US=> NH71WXVUSU6JRWK=
GP5d Mm[1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmrpTWM2OD14Lkm3N|k1KM7:TR?= MWLTRW5ITVJ?
MOLT-4 NHTZXYpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1K1V2lEPTB;Nz6wNlE{PSEQvF2= MWHTRW5ITVJ?
NCI-H28 NXf6cWZuT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWXJR|UxRTdwMU[0NFUh|ryP NFXUcYhUSU6JRWK=
MN-60 MoLJS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYW0T4NrUUN3ME23MlI5ODh7IN88US=> NUjUSFRbW0GQR1XS
RMG-I MoXkS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mk\iTWM2OD15LkO5Nlk3KM7:TR?= NGfNNHBUSU6JRWK=
COLO-800 NIfF[oVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYLJR|UxRTdwNEG0OFYh|ryP Mn7kV2FPT0WU
DB M4nlO2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYjJR|UxRTdwNkGwNFUh|ryP Mkm0V2FPT0WU
Ca-Ski NUXYfHVmT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmPRTWM2OD15Lk[0NlU6KM7:TR?= MmG1V2FPT0WU
HEL MUXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoriTWM2OD15LkexNlA{KM7:TR?= MkGzV2FPT0WU
NH-12 M4jxUWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXfJR|UxRTdwN{K4NFgh|ryP MWTTRW5ITVJ?
LB373-MEL-D MVfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MojxTWM2OD15Lke2O|cyKM7:TR?= MoXiV2FPT0WU
SW900 NHvpdlFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlHPTWM2OD15LkiyNVIyKM7:TR?= NWT4blRxW0GQR1XS
JVM-3 NGjsfpZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWrJR|UxRTdwOEm1PVkh|ryP NHXDZZRUSU6JRWK=
OAW-28 M1HBeWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFq2O3BKSzVyPUeuPVQ2PzhizszN MVjTRW5ITVJ?
KURAMOCHI M3H2S2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MorXTWM2OD15Lkm0PFEyKM7:TR?= M3;3RnNCVkeHUh?=
BE-13 NWnYNplLT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWT4fGtbUUN3ME23Mlk5OTF{IN88US=> NU\kTnpDW0GQR1XS
VMRC-RCZ NV7ZfXFIT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUj5S4cxUUN3ME24MlAyPjl5IN88US=> M3jVNXNCVkeHUh?=
NCI-H727 MkTSS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NV[yW2dnUUN3ME24MlExPDJizszN NXPwR2RwW0GQR1XS
SW1710 M2HuZmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{PDUmlEPTB;OD6xPFUyPSEQvF2= MnvwV2FPT0WU
D-502MG M2X5cWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUPJR|UxRThwMkmyPFIh|ryP MWTTRW5ITVJ?
NCI-H1993 NYjsS5V3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{S4[2lEPTB;OD6zN|Y{OSEQvF2= NVfhU21iW0GQR1XS
SCC-4 Ml7XS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYnjS2RYUUN3ME24MlQ1ODV7IN88US=> NIXBPXVUSU6JRWK=
HAL-01 NYPtPWZzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYK3dppvUUN3ME24MlUyQTFizszN NILpUFNUSU6JRWK=
GT3TKB NYLTOFNIT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGTnSJRKSzVyPUiuOlc6PjRizszN NF\5fHdUSU6JRWK=
SK-OV-3 NFLmdVhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NF3xNllKSzVyPUiuO|E{OjlizszN NGX2R2lUSU6JRWK=
COLO-829 MnW3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmX4TWM2OD16LkiwPVc3KM7:TR?= MV;TRW5ITVJ?
OCI-AML2 NVTJRphKT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mn7PTWM2OD16Lkm1OFgyKM7:TR?= M4PFcHNCVkeHUh?=
OS-RC-2 M3XDSmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{jsTmlEPTB;OT6wNlE6KM7:TR?= MYXTRW5ITVJ?
BFTC-909 M1m4eGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkXCTWM2OD17LkC2O|k6KM7:TR?= NWLQVZVlW0GQR1XS
EW-11 M{DrZWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4XtNGlEPTB;OT6xO|Y2OyEQvF2= M{myVnNCVkeHUh?=
HCE-4 M{PtUGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{fmc2lEPTB;OT6yNVU2QCEQvF2= M1ewS3NCVkeHUh?=
BALL-1 MUfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVHJR|UxRTlwMkG5NFch|ryP MlXEV2FPT0WU
SF539 MmG1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mn\lTWM2OD17LkKzOVYzKM7:TR?= M3P4VHNCVkeHUh?=
CAMA-1 MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4CxTWlEPTB;OT6yPFEzQCEQvF2= NWfubJp{W0GQR1XS
C32 MXnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MV\JR|UxRTlwM{OwOlQh|ryP M4\RbHNCVkeHUh?=
NCI-H1703 NVTuV5dVT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NV3m[mNsUUN3ME25MlM1Ozd3IN88US=> M2nsRnNCVkeHUh?=
NCI-H1650 NVvoO3pQT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVjJR|UxRTlwNkC5OFYh|ryP NXzTeGdkW0GQR1XS
NCI-H1563 MlvrS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlXMTWM2OD17Lke2NFMyKM7:TR?= MkXGV2FPT0WU
CAL-85-1 M3O3PGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGTO[XpKSzVyPUmuPFc{QDNizszN NYXVfmluW0GQR1XS
UM-UC-3 NF3RepZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVPjXG9YUUN3ME25Mlk2ODNizszN NU\BbXJ[W0GQR1XS
BxPC-3 NH\zW45Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXjJR|UxRTFyLkC5O|Ih|ryP NHyycpVUSU6JRWK=
MHH-PREB-1 NYKxb5ZKT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4PtSGlEPTB;MUCuNVk6QSEQvF2= M3PWfHNCVkeHUh?=
DEL M3TtNmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkPLTWM2OD1zMD6zPVQ3KM7:TR?= NVrnV4RIW0GQR1XS
HuCCT1 NH\iNINIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3zSU2lEPTB;MUCuOlA{OyEQvF2= MYnTRW5ITVJ?
OVCAR-4 NVS2e|JlT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWSxWlRwUUN3ME2xNE45QDN3IN88US=> MnzhV2FPT0WU
CAL-72 NF;MR3hIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1LrbGlEPTB;MUCuPVM6OSEQvF2= MWLTRW5ITVJ?
HCC1954 MkHxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWrxdYhiUUN3ME2xNU4xPzV2IN88US=> M2HRcXNCVkeHUh?=
EFO-21 NIexOFNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYi4SmFbUUN3ME2xNU4yODR3IN88US=> MU\TRW5ITVJ?
FTC-133 MoXxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYHwc3poUUN3ME2xNU4yPDB5IN88US=> NIi2d2hUSU6JRWK=
SK-MEL-24 MoLjS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXXB[4k4UUN3ME2xNU4zOzZ4IN88US=> NH\lVW9USU6JRWK=
UACC-62 NX:5Z5RbT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3jpSWlEPTB;MUGuNlM3QCEQvF2= NWLCZW8{W0GQR1XS
NCI-H650 NHnVOlRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1e4[WlEPTB;MUGuNlQyQCEQvF2= NXq0SJBzW0GQR1XS
ALL-PO MXzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEe2ZWhKSzVyPUGxMlI2OTJizszN MlfDV2FPT0WU
T84 M2TVUWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3nrVGlEPTB;MUGuN|kxPyEQvF2= MkG2V2FPT0WU
IST-MEL1 NV;aW48zT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmfETWM2OD1zMT60OVU6KM7:TR?= Mn;NV2FPT0WU
SW626 MnPOS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NF7kTG9KSzVyPUGxMlU4PTVizszN M4LoTXNCVkeHUh?=
RPMI-2650 MYHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3zFWGlEPTB;MUGuOVg5PSEQvF2= MlvmV2FPT0WU
MC-IXC NF3odVNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnL1TWM2OD1zMT62O|I5KM7:TR?= M{nmdnNCVkeHUh?=
HOP-62 NXyyZ2UyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mk\qTWM2OD1zMT62O|Y1KM7:TR?= MXrTRW5ITVJ?
NOS-1 MnzFS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1\6Z2lEPTB;MUGuO|ExQSEQvF2= NYDSclRwW0GQR1XS
SW1573 NUDwe3p[T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MU\JR|UxRTFzLkeyPVUh|ryP NUjYWXh2W0GQR1XS
WM-115 NWW3W2pvT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVn3ZYN2UUN3ME2xNU44PTh6IN88US=> Mon0V2FPT0WU
HuO9 MoTDS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mn7FTWM2OD1zMT64O|c1KM7:TR?= NEjKOW9USU6JRWK=
YAPC Mm\yS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoX6TWM2OD1zMT65NlU6KM7:TR?= NXnYW5V4W0GQR1XS
MDA-MB-453 M{HWcGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoDkTWM2OD1zMT65OVE2KM7:TR?= NH\QZ|RUSU6JRWK=
NCI-H596 M1;JdGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEWxc5RKSzVyPUGyMlA{PjlizszN MWfTRW5ITVJ?
A172 MVfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVjJR|UxRTF{LkC3PVgh|ryP MnrmV2FPT0WU
RS4-11 NVHydFdyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmjlTWM2OD1zMj6xO|I2KM7:TR?= MlixV2FPT0WU
HCC1937 MXnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHHPc45KSzVyPUGyMlc2PjRizszN NVvKUnF3W0GQR1XS
SW837 MXTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmrkTWM2OD1zMj65NFI5KM7:TR?= NXHpRmh5W0GQR1XS
NMC-G1 MmHMS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{D0fWlEPTB;MUKuPVI{PCEQvF2= MkfGV2FPT0WU
PFSK-1 NVLHd5JuT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mk\LTWM2OD1zMz6wOkDPxE1? MX;TRW5ITVJ?
DBTRG-05MG NUT5bVhpT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYHPTJgzUUN3ME2xN{4xPjN{IN88US=> M4\2NXNCVkeHUh?=
SK-UT-1 NUnabpVqT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnHWTWM2OD1zMz6xNFg{KM7:TR?= NYHEVmdIW0GQR1XS
OVCAR-5 MlXOS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NV23OJZ7UUN3ME2xN{4yPTl|IN88US=> Mny0V2FPT0WU
8505C NWLxe|J3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnnaTWM2OD1zMz6yNFY4KM7:TR?= MljjV2FPT0WU
SK-MEL-1 M17Dd2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NF;aWVRKSzVyPUGzMlcyOzVizszN MWfTRW5ITVJ?
LK-2 M4[5PGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2nzR2lEPTB;MUOuO|Y{QSEQvF2= Mne1V2FPT0WU
OE33 NGqzXVlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVzlWlI2UUN3ME2xN{44QDZizszN Mlv6V2FPT0WU
Ramos-2G6-4C10 NETPWIdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVHTSYY{UUN3ME2xOE4xOjB{IN88US=> NYXrc|V5W0GQR1XS
EW-13 NVLZT2hRT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWDiOIdrUUN3ME2xOE4xOzV{IN88US=> Mn\rV2FPT0WU
NCI-H1793 NWPnbJFnT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIj4VWdKSzVyPUG0MlIxQDdizszN NXXhXpdFW0GQR1XS
BHT-101 NH3UOGdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVzJR|UxRTF2LkK0NUDPxE1? M2fNUnNCVkeHUh?=
RKO MYrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MonlTWM2OD1zND61NFc2KM7:TR?= MkW2V2FPT0WU
NEC8 M4X2VGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mo\oTWM2OD1zND61OFczKM7:TR?= M13YR3NCVkeHUh?=
PANC-10-05 NWLIcXNqT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NV;zSFFUUUN3ME2xOE43OjR5IN88US=> NXf6U4pzW0GQR1XS
NCI-H2030 NWPVRWZPT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NX3oNHZoUUN3ME2xOE43PDR6IN88US=> NGXzcYZUSU6JRWK=
C2BBe1 M3y3fWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWrJR|UxRTF2Lke2OEDPxE1? M17EOXNCVkeHUh?=
EM-2 MVjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHzP[o5KSzVyPUG0Mlg2PzZizszN MXTTRW5ITVJ?
HCC1395 MXzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGW1NY1KSzVyPUG0Mlk{OzhizszN MYHTRW5ITVJ?
A2058 NITGd|FIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWGwd2o3UUN3ME2xOU4xPDB7IN88US=> M2C1ZnNCVkeHUh?=
SW1463 M{\VNGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{ixZmlEPTB;MUWuNFQ5PSEQvF2= NH;hOVhUSU6JRWK=
J82 NWLFcZVYT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWHFTZNsUUN3ME2xOU4xPTdizszN NYXKNIRnW0GQR1XS
CAL-120 NHXDc3hIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXvJR|UxRTF3LkG0OFch|ryP NIrmUJRUSU6JRWK=
COLO-824 MY\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEHzTYtKSzVyPUG1MlE2PzlizszN MWjTRW5ITVJ?
LNCaP-Clone-FGC MlXjS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NV3Bc4VFUUN3ME2xOU41OjR6IN88US=> MmfMV2FPT0WU
CP66-MEL NILBVIRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3HXUGlEPTB;MUWuOFY5QCEQvF2= NXq4fVlRW0GQR1XS
OC-314 MkjtS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVq5fXpbUUN3ME2xOU41PzF2IN88US=> M4r5enNCVkeHUh?=
OVCAR-8 MlfVS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NI\IW4tKSzVyPUG1Mlg5PjFizszN MVrTRW5ITVJ?
MFE-280 NG\XbYJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MkjYTWM2OD1zNj6wOFg5KM7:TR?= M2H6NXNCVkeHUh?=
MHH-NB-11 M{jDbmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHfCVoVKSzVyPUG2MlA5OzlizszN NEixe5ZUSU6JRWK=
SW1990 MWHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlfCTWM2OD1zNj6xO|U2KM7:TR?= M4HjZXNCVkeHUh?=
U-266 NYPnVmhDT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYHEW5VjUUN3ME2xOk4zOjl7IN88US=> NULYVoFTW0GQR1XS
MFM-223 NXTHTnlzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmLZTWM2OD1zNj6zPVY2KM7:TR?= MWHTRW5ITVJ?
L-363 NGjJNIxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIjJPHNKSzVyPUG2MlQ2PzdizszN M33t[3NCVkeHUh?=
MCF7 NXnHflFwT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NU\ybow5UUN3ME2xOk41PzJ|IN88US=> MULTRW5ITVJ?
SK-MEL-3 MVnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4XMb2lEPTB;MU[uOFc5PyEQvF2= NEPn[4dUSU6JRWK=
HH MkHaS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUXhRWV1UUN3ME2xOk42OTZ{IN88US=> NH6zR3VUSU6JRWK=
no-10 M1HhdGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3LSOGlEPTB;MU[uOlM1OyEQvF2= MYPTRW5ITVJ?
HuP-T3 MXfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NIG4VZFKSzVyPUG2MlY2PzZizszN MYHTRW5ITVJ?
QIMR-WIL NYnLVGlrT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{fEVGlEPTB;MU[uO|ExPSEQvF2= NVzjW3NUW0GQR1XS
NCI-H1092 MmLzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVXE[Y9PUUN3ME2xOk45OzF4IN88US=> MoPLV2FPT0WU
MZ2-MEL M4O2emdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4fRdGlEPTB;MU[uPFQxOyEQvF2= MofIV2FPT0WU
ES3 M1j0Wmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3LHO2lEPTB;MU[uPVE{PCEQvF2= MX7TRW5ITVJ?
COLO-684 MVHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWfJR|UxRTF4Lkm0O|ch|ryP NUXRUmdYW0GQR1XS
NCI-H661 MoDWS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGjMVoRKSzVyPUG2Mlk3QTRizszN NGPFfppUSU6JRWK=
CP50-MEL-B MnLhS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWTjV3ZRUUN3ME2xO{4xOzR|IN88US=> M1z6TXNCVkeHUh?=
NCI-H2405 MonNS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIrnTXVKSzVyPUG3MlE6PzRizszN M{DNZXNCVkeHUh?=
U-2-OS NUDmVY53T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4LyTmlEPTB;MUeuOVMxPyEQvF2= MljEV2FPT0WU
RERF-LC-MS MmrnS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mn\RTWM2OD1zNz61OVA5KM7:TR?= MoPVV2FPT0WU
NCI-H2342 Mo\FS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUniZ|NFUUN3ME2xO{42PTdizszN NEOxdVRUSU6JRWK=
ES8 MXjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MknETWM2OD1zNz62NFg4KM7:TR?= MmjvV2FPT0WU
MOLT-16 MULHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoTsTWM2OD1zNz64PVM1KM7:TR?= NIHwXVNUSU6JRWK=
RH-18 NHjrblBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXzYSHVIUUN3ME2xPE4xODN3IN88US=> MmTPV2FPT0WU
D-283MED NEPGWlNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWTJR|UxRTF6LkCwPFgh|ryP MkHkV2FPT0WU
RCC10RGB MkDkS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIK0[nRKSzVyPUG4MlA2PTlizszN MVzTRW5ITVJ?
NCI-H1437 Ml70S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MkTZTWM2OD1zOD6xOlQyKM7:TR?= MnLUV2FPT0WU
SW982 NVLocGw1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVrtd5NOUUN3ME2xPE4zPjdzIN88US=> M{HVTnNCVkeHUh?=
IST-MES1 MWfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVjMOXpyUUN3ME2xPE41PDJ6IN88US=> MmO2V2FPT0WU
A704 MVjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXfJR|UxRTF6LkS3OVMh|ryP NGDU[YZUSU6JRWK=
ESS-1 Ml3QS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NW\pd5FrUUN3ME2xPE42OjB3IN88US=> NIj3ToNUSU6JRWK=
SCH M4XqUGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFPP[opKSzVyPUG4MlY1PTZizszN NFvv[pJUSU6JRWK=
COLO-320-HSR NFjudYlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVfub5A5UUN3ME2xPE44PDZizszN MmXIV2FPT0WU
Mo-T NWm5Z25bT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYTjdWJJUUN3ME2xPE45OjB2IN88US=> MYrTRW5ITVJ?
Saos-2 NYPhcVdqT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIWwOoZKSzVyPUG5MlEyPjJizszN NGHR[nZUSU6JRWK=
SW684 NGTib2ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnjuTWM2OD1zOT6xN|I3KM7:TR?= NX;GdGpHW0GQR1XS
KMOE-2 MlS2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3nwSWlEPTB;MUmuNlI1OiEQvF2= NEH0[XVUSU6JRWK=
MMAC-SF NHTMe3hIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVnJR|UxRTF7LkK2NFch|ryP M{nCUHNCVkeHUh?=
JAR NXqwTFR{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlHBTWM2OD1zOT6yPVkh|ryP Mo\XV2FPT0WU
SK-MEL-28 NHezWHFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYn2TXlWUUN3ME2xPU4{OzZ|IN88US=> M4nNfnNCVkeHUh?=
KNS-81-FD NHPlU2VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVfJR|UxRTF7LkW0Olgh|ryP MYLTRW5ITVJ?
ES7 M1XBbWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NX3qfnVoUUN3ME2xPU43Ojl{IN88US=> NWD0SHBPW0GQR1XS
AsPC-1 Mo\wS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFHm[VFKSzVyPUG5MlY1PzFizszN NXraTVNYW0GQR1XS
NCI-H1155 NFLJeFdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWfJR|UxRTF7LkeyN|gh|ryP NUnPWVc2W0GQR1XS
KYSE-510 M2jMdmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{PK[WlEPTB;MUmuPFc1QCEQvF2= M2nEeHNCVkeHUh?=
ES1 M{jlUmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXXJR|UxRTF7LkmyNVMh|ryP MVXTRW5ITVJ?
PC-3 MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWPJR|UxRTF7Lkm2NFQh|ryP MVXTRW5ITVJ?
GCT M2fVNWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFvySVlKSzVyPUKwMlMxOjZizszN MUTTRW5ITVJ?
KARPAS-299 M{DTUmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXvSUnY3UUN3ME2yNE4{PDJ{IN88US=> NGjzWJVUSU6JRWK=
DOHH-2 NYrkTVF3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFj5OVhKSzVyPUKwMlU1PjNizszN M{PSWHNCVkeHUh?=
COLO-741 NEfBdo9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVrJR|UxRTJyLk[2JO69VQ>? NE\FOZdUSU6JRWK=
NCI-H1395 NYDXZ5ZCT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEjLO2pKSzVyPUKwMlY3QTdizszN NUPhSFNxW0GQR1XS
HCC1187 MYrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3:5c2lEPTB;MkCuOlc{PCEQvF2= MYPTRW5ITVJ?
Becker MUXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHruZ|FKSzVyPUKwMlczODFizszN MV;TRW5ITVJ?
LU-134-A NFPWOmVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4rzUmlEPTB;MkGuNVAzPiEQvF2= NIjiS|BUSU6JRWK=
MKN45 M374eWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYTOUVRmUUN3ME2yNU4yPTVzIN88US=> NVvh[mRmW0GQR1XS
LC-2-ad NUnqepMxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3vYVmlEPTB;MkGuNlczQSEQvF2= MYXTRW5ITVJ?
EW-24 MYDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGK2ZXJKSzVyPUKxMlM6PDVizszN M4\kSXNCVkeHUh?=
SK-N-AS MmjZS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MV\JR|UxRTJzLkiyO|Yh|ryP Mlz2V2FPT0WU
NCI-H2052 NUnHOHBnT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYjJR|UxRTJzLki5OlMh|ryP M175NnNCVkeHUh?=
A4-Fuk NGHac4pIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlLVTWM2OD1{Mj6xOFE6KM7:TR?= NH\WNJNUSU6JRWK=
NB10 MWXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXTJR|UxRTJ{LkKzO|Eh|ryP MmjmV2FPT0WU
CHP-212 M1nBfGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnLSTWM2OD1{Mj6zNlIzKM7:TR?= MkfSV2FPT0WU
KM12 M13zR2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHH0TJRKSzVyPUKyMlM2PiEQvF2= NYflSlk2W0GQR1XS
JEG-3 MmPGS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3;UemlEPTB;MkKuN|c5KM7:TR?= M1nIWXNCVkeHUh?=
LN-405 NFTXbGdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1m4eGlEPTB;MkKuOVkyOyEQvF2= NIrwNXdUSU6JRWK=
HCT-15 MlHIS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{nsfmlEPTB;MkKuO|Q1OSEQvF2= NILIPG5USU6JRWK=
MLMA NVjvZ|hYT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIHRPG1KSzVyPUKyMlc1PyEQvF2= NGDWPXRUSU6JRWK=
GI-1 MVrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVzJR|UxRTJ{Lke2OVgh|ryP MkHnV2FPT0WU
RT-112 MVPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4TUXGlEPTB;MkKuPFYyPiEQvF2= MnzWV2FPT0WU
MPP-89 MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWHJR|UxRTJ{Lki2OlEh|ryP NFnGV2ZUSU6JRWK=
A3-KAW NFuzb5ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGHHdIVKSzVyPUKzMlExODNizszN M37H[nNCVkeHUh?=
KALS-1 MluzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXTJR|UxRTJ|LkG0NVQh|ryP NGrJOlJUSU6JRWK=
SF126 MmDGS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4ntSGlEPTB;MkOuOlkzPCEQvF2= NE\DRXpUSU6JRWK=
SiHa M2DhVmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFzLZ|BKSzVyPUKzMlk{OjdizszN MmP5V2FPT0WU
MDA-MB-415 NH\3NnNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEHU[WFKSzVyPUKzMlk1QTlizszN NHfTd5FUSU6JRWK=
Daoy MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1;KXmlEPTB;MkSuNVI3KM7:TR?= MWPTRW5ITVJ?
COR-L23 NWXLNVZET3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVjMRVNqUUN3ME2yOE4yPzZ5IN88US=> MmLSV2FPT0WU
KG-1 M1jCUmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEXLU3FKSzVyPUK0MlE6OjhizszN NGnjSmRUSU6JRWK=
L-428 MUPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGXDfIFKSzVyPUK0MlU4QTFizszN NGPaSYFUSU6JRWK=
NCI-H520 NImzTJRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWLJR|UxRTJ2Lki4OlEh|ryP NXzwZ5p[W0GQR1XS
COLO-792 M1rOR2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFHOfohKSzVyPUK1MlI4OzJizszN NHL3UnhUSU6JRWK=
NB12 NXHhPIFOT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NX21bFhTUUN3ME2yOU4zQTR5IN88US=> MYPTRW5ITVJ?
GAK NGXXTplIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MkLNTWM2OD1{NT6yPVY{KM7:TR?= MVLTRW5ITVJ?
SW780 M2\1WGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIPZZoJKSzVyPUK1MlMzPjRizszN M1zoTXNCVkeHUh?=
GB-1 NFrmenVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIrMPZZKSzVyPUK1MlQxPjlizszN MkPOV2FPT0WU
P12-ICHIKAWA NXHoZYZsT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXrscotyUUN3ME2yOU41Pzh3IN88US=> M3zzbHNCVkeHUh?=
NCI-H1651 NXqyU|U{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NI\XXIhKSzVyPUK1MlU6PyEQvF2= MYrTRW5ITVJ?
KE-37 NVPsb3pbT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoTmTWM2OD1{NT63N|E2KM7:TR?= M2HUNXNCVkeHUh?=
CCRF-CEM NIDpc4lIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXnJR|UxRTJ3Lkm2O{DPxE1? Mn;ZV2FPT0WU
SF295 NUPkT3lMT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1Lsb2lEPTB;Mk[uNFQzPSEQvF2= NELUVphUSU6JRWK=
G-361 NHfYU49Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mny4TWM2OD1{Nj6xNFI4KM7:TR?= Mn7EV2FPT0WU
HOP-92 M3vXZmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFP6PZVKSzVyPUK2MlEzOjZizszN NVzaZXJQW0GQR1XS
UMC-11 MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFnaZ2xKSzVyPUK2MlQ2OTRizszN MYDTRW5ITVJ?
IST-SL1 M1fqPWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXjJR|UxRTJ4Lk[1PVEh|ryP MUDTRW5ITVJ?
TE-11 NFnifW1Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUHOTo03UUN3ME2yOk44PzV{IN88US=> NUfsd20yW0GQR1XS
NCI-H1304 NWPJeI5GT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYTFdZlZUUN3ME2yOk46OTB6IN88US=> MXTTRW5ITVJ?
SJSA-1 Mme1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NV\Rb4VWUUN3ME2yO{4xOTd4IN88US=> M2rpbXNCVkeHUh?=
BCPAP NELaNmRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXfJR|UxRTJ5LkGzO{DPxE1? NF7TSHBUSU6JRWK=
HTC-C3 NFjObnFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnS5TWM2OD1{Nz6yOVYyKM7:TR?= NEHO[4FUSU6JRWK=
EW-16 M{\sN2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYHJR|UxRTJ5LkK5OFch|ryP NIfXNJlUSU6JRWK=
HT-144 MWXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYXIcYRYUUN3ME2yO{41ODN{IN88US=> NVr1[Zd5W0GQR1XS
MHH-ES-1 NEHKRoZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUfJR|UxRTJ5LkS0OFch|ryP MnzvV2FPT0WU
T98G MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4TSfGlEPTB;MkeuOVg1PiEQvF2= M3HScXNCVkeHUh?=
RPMI-8866 MkP3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYDnO41bUUN3ME2yO{44PTZ{IN88US=> NV[1U293W0GQR1XS
BEN MorHS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYTJSVVbUUN3ME2yO{45PTF5IN88US=> NIT1b5NUSU6JRWK=
MDA-MB-231 NH3OS|lIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWLJR|UxRTJ6LkK3PVUh|ryP MlTyV2FPT0WU
HuH-7 MnW4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mmf6TWM2OD1{OD60NFI5KM7:TR?= NIfXU3hUSU6JRWK=
SK-N-FI NXrvTlQxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{D3NWlEPTB;MkiuOFM{KM7:TR?= MUDTRW5ITVJ?
AN3-CA MV3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGiwcpNKSzVyPUK4MlQ{QTVizszN NXLCcW9UW0GQR1XS
EGI-1 NUTJNndYT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlHpTWM2OD1{OD61PVI5KM7:TR?= MYjTRW5ITVJ?
697 M{PBWGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NULVV4ZUUUN3ME2yPE43OzNzIN88US=> M3qwZXNCVkeHUh?=
TCCSUP NV7HUFVZT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{W2WmlEPTB;MkiuOlQyQCEQvF2= MXjTRW5ITVJ?
GR-ST NEDpdnhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1zQTmlEPTB;MkiuOlY6PiEQvF2= NX2xemZTW0GQR1XS
SK-N-DZ MlHyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlTkTWM2OD1{OD62PFg2KM7:TR?= NV6xfYRjW0GQR1XS
MIA-PaCa-2 NHHpRXNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3HqVmlEPTB;MkiuO|k2QSEQvF2= NVLTToJ1W0GQR1XS
IGR-1 MVnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkHLTWM2OD1{OD64PFc1KM7:TR?= NGGxUZdUSU6JRWK=
BFTC-905 NWrpUJhLT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGTBUmRKSzVyPUK5MlI4ODVizszN Mn3RV2FPT0WU
NCI-H1581 NX;HXGtmT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MV;JR|UxRTJ7LkOxOFUh|ryP Mn7kV2FPT0WU
RD NHnNUHlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2T2WmlEPTB;MkmuOVI{OyEQvF2= M1ryXHNCVkeHUh?=
SF268 M2DROGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NETsSItKSzVyPUK5MlU6OzFizszN M1frO3NCVkeHUh?=
SHP-77 MlKzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnPRTWM2OD1{OT62NVgzKM7:TR?= NF;BSZZUSU6JRWK=
D-566MG MUfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoPOTWM2OD1{OT65N|k{KM7:TR?= NEmxWVlUSU6JRWK=
TGBC1TKB NEnUVlFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVTJR|UxRTNyLkGyN|gh|ryP NYjsbJVlW0GQR1XS
MEL-HO NEn1OolIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXvpOIZHUUN3ME2zNE4yPDJ|IN88US=> M1jXc3NCVkeHUh?=
SJRH30 NX\6bWdUT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXeyb2tWUUN3ME2zNE4zOTB6IN88US=> NI\v[JJUSU6JRWK=
D-336MG MoHXS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NV7BOI1SUUN3ME2zNE4zQDl{IN88US=> M{fBTXNCVkeHUh?=
C3A NX22PHVsT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWPObmxrUUN3ME2zNE4zQTJ5IN88US=> NEj2XHJUSU6JRWK=
Calu-6 Mme5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NX7rZo5mUUN3ME2zNE4zQTZ|IN88US=> Mme1V2FPT0WU
MZ1-PC NUDMbJB4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmnOTWM2OD1|MD6zPVMh|ryP M1rZSXNCVkeHUh?=
KYSE-70 MkDhS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NX3tTFV5UUN3ME2zNE42OTF2IN88US=> MmHSV2FPT0WU
CAPAN-1 NYr0eI5ST3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWjJR|UxRTNyLkWxPFEh|ryP M3PSW3NCVkeHUh?=
DK-MG NXjLSpp4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MULJR|UxRTNyLkW0OVYh|ryP MnLQV2FPT0WU
SK-HEP-1 NEjRR2pIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2XC[GlEPTB;M{CuOlMzPiEQvF2= M3vIUnNCVkeHUh?=
MS-1 MYXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFzYeZFKSzVyPUOwMlg5QDlizszN M3PteHNCVkeHUh?=
GI-ME-N MknhS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHPjcnJKSzVyPUOxMlA2PzFizszN MXrTRW5ITVJ?
NCI-H510A NFKyO|NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVjJR|UxRTNzLkSwNFYh|ryP MlK2V2FPT0WU
NB17 NVW3XVVGT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXLJR|UxRTNzLkWxPFUh|ryP M4Gyd3NCVkeHUh?=
639-V NITDVoFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYXJR|UxRTNzLkWyOFMh|ryP NIm3VYlUSU6JRWK=
CAL-51 NIDKfmlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MX;JR|UxRTNzLkW2Olch|ryP M2rCVHNCVkeHUh?=
HGC-27 MX7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1fMN2lEPTB;M{GuOVg4OyEQvF2= MWXTRW5ITVJ?
GOTO MmCyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVPJR|UxRTNzLki1NFYh|ryP NEHKfVFUSU6JRWK=
ChaGo-K-1 NXXsflVwT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmTYTWM2OD1|Mj6wNFch|ryP NEnLfWJUSU6JRWK=
RO82-W-1 NW\le4JNT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NF7Md4NKSzVyPUOyMlE3ODRizszN NV;vfXNZW0GQR1XS
SH-4 MYfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlPETWM2OD1|Mj6xPFU5KM7:TR?= NGO5c2xUSU6JRWK=
A204 MX;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXfJR|UxRTN{LkWwOlkh|ryP M4j1[HNCVkeHUh?=
DMS-273 M3P6T2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHm2UZpKSzVyPUOyMlU{OjJizszN MULTRW5ITVJ?
KGN MlPtS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnXpTWM2OD1|Mj62N|Mh|ryP NEHtXIdUSU6JRWK=
SK-MEL-2 MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Ml\KTWM2OD1|Mj62OVI4KM7:TR?= MWPTRW5ITVJ?
NCI-H2228 NI\RN3dIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MoO4TWM2OD1|Mj62OlAzKM7:TR?= NX7LOVc2W0GQR1XS
MKN28 NFS4XZpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYnGcWFJUUN3ME2zNk44QDN6IN88US=> NEPJc|FUSU6JRWK=
H-EMC-SS NFfiVpdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlXXTWM2OD1|Mj65Olc5KM7:TR?= NHzMSXdUSU6JRWK=
ATN-1 MmezS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVvw[lRJUUN3ME2zN{4yPDF4IN88US=> NUPOdW5sW0GQR1XS
D-263MG MnXOS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MkfaTWM2OD1|Mz64N|c5KM7:TR?= MoC0V2FPT0WU
LU-135 NIDiWHBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHTtT|VKSzVyPUOzMlg5OjlizszN MU\TRW5ITVJ?
C8166 MUTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVrJR|UxRTN|Lki4OVQh|ryP M4HoenNCVkeHUh?=
T-24 NYHnTVdjT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVqzb3dEUUN3ME2zOE4xOjB3IN88US=> NHfnUXBUSU6JRWK=
Mewo M1vC[mdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVvJR|UxRTN2LkGzOFkh|ryP MVXTRW5ITVJ?
22RV1 MmqyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUHJR|UxRTN2LkG3OVQh|ryP NYrIcYNHW0GQR1XS
KM-H2 MX;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFG1eXlKSzVyPUO0MlE4PzlizszN NH;SdHRUSU6JRWK=
NCI-H2122 M1XXPWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MW\JR|UxRTN2LkO0O|Eh|ryP NFPufoFUSU6JRWK=
ABC-1 MUTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlHwTWM2OD1|ND6zOlk{KM7:TR?= NFjZSWRUSU6JRWK=
NCI-H1355 MVXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWDDPGdbUUN3ME2zOE4{QDh7IN88US=> Ml\QV2FPT0WU
NOMO-1 M3LqeGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mlu3TWM2OD1|ND61O|A{KM7:TR?= Mn\nV2FPT0WU
MZ7-mel NX:2Z2FUT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYfJR|UxRTN2Lk[0PFch|ryP M2rJTXNCVkeHUh?=
NCI-H810 MYrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYLJR|UxRTN2LkeyO|gh|ryP M2npZnNCVkeHUh?=
D-392MG MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NUi0VJVPUUN3ME2zOU4xPTZ3IN88US=> NWPQOVVyW0GQR1XS
LB771-HNC NGnDbGZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFLmV|hKSzVyPUO1MlE3PThizszN MWLTRW5ITVJ?
COLO-679 NHjGPZVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWfRPFVyUUN3ME2zOU4{QDhizszN M3\iT3NCVkeHUh?=
SK-PN-DW MlLsS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUK0eVNIUUN3ME2zOU41OzZ7IN88US=> MmPFV2FPT0WU
VA-ES-BJ MVXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmHLTWM2OD1|NT60OlQ6KM7:TR?= NVu0XGRSW0GQR1XS
KNS-42 MUjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoniTWM2OD1|NT61PFI3KM7:TR?= NXPUfWNuW0GQR1XS
RVH-421 MkDYS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mnm4TWM2OD1|NT63OlQ2KM7:TR?= NEWzSGJUSU6JRWK=
P30-OHK NILueGpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1TuXmlEPTB;M{WuPFc2OiEQvF2= MofqV2FPT0WU
G-402 MmnqS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3;SWmlEPTB;M{WuPVg3PyEQvF2= NVj5NI84W0GQR1XS
S-117 MVnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NH3ibmNKSzVyPUO2MlMxODhizszN NITTcoZUSU6JRWK=
RXF393 MYrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGG5cJpKSzVyPUO2MlM4QDVizszN NIrobJFUSU6JRWK=
LCLC-103H MXvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFPadZZKSzVyPUO2Mlc5ODNizszN NX7afmJ1W0GQR1XS
U-118-MG M{PTO2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4nZUGlEPTB;M{[uPFg1PyEQvF2= M1OzUnNCVkeHUh?=
8-MG-BA MmfTS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXfJR|UxRTN4Lkm0PFMh|ryP NIXEcYtUSU6JRWK=
MFH-ino MXHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXLJR|UxRTN5LkOzO|Eh|ryP NUTtWWlKW0GQR1XS
NCI-H23 MX;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUXJR|UxRTN5LkSxPVYh|ryP MmP1V2FPT0WU
NCI-H446 MkLIS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnriTWM2OD1|Nz60PFYzKM7:TR?= M2XlfHNCVkeHUh?=
LU-99A NUH3PGl{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXjJR|UxRTN5LkW3N|Eh|ryP M1zsdHNCVkeHUh?=
KP-N-YN NWHZfnE{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3vkRmlEPTB;M{euOlE6PSEQvF2= M1LKWHNCVkeHUh?=
SCC-9 Mn23S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MV;JR|UxRTN5Lke4N|gh|ryP Mlv3V2FPT0WU
EFM-19 MUHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MW\JR|UxRTN5Lke5Olch|ryP NX\Udll1W0GQR1XS
A427 M2Ttbmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MULJR|UxRTN5LkmxNFch|ryP M13UVXNCVkeHUh?=
LB831-BLC NHzadYdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlW4TWM2OD1|OD62NFM6KM7:TR?= MYXTRW5ITVJ?
HOS NYPIems3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHrnbllKSzVyPUO5MlYzPzNizszN MmLzV2FPT0WU
LAN-6 NIrHWI9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1PoZmlEPTB;NECuNFEyOiEQvF2= MVnTRW5ITVJ?
U251 NI\Xe3BIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXW2TGY6UUN3ME20NE41ODV2IN88US=> MX\TRW5ITVJ?
SNU-387 NIXN[4RIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVTJR|UxRTRyLkS1OVMh|ryP M2C0R3NCVkeHUh?=
DMS-79 MlrOS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2P5O2lEPTB;NECuOVg5QSEQvF2= MYXTRW5ITVJ?
SK-LU-1 MlW0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoHMTWM2OD12MD62OVY5KM7:TR?= M{Dlb3NCVkeHUh?=
HT NUntc4ZWT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUGwOpk4UUN3ME20NE43PjN7IN88US=> M3XiPHNCVkeHUh?=
KP-N-YS MljVS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MkfSTWM2OD12MD62O|Y5KM7:TR?= NIPFO3ZUSU6JRWK=
DMS-114 M2DuOmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXLJR|UxRTRyLkizO|Qh|ryP MnLaV2FPT0WU
HUTU-80 NHv5O|NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlzLTWM2OD12MT6wOVY6KM7:TR?= NHzGOIRUSU6JRWK=
ONS-76 NFW1U5hIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWHJR|UxRTRzLkS3NFkh|ryP M2n3ZnNCVkeHUh?=
A673 M{jsOGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MX\JR|UxRTRzLkWxOVch|ryP MU\TRW5ITVJ?
HPAF-II NFLadGtIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{HrbmlEPTB;NEGuOlcxQSEQvF2= NFntPFFUSU6JRWK=
UACC-257 Ml:2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXrJR|UxRTRzLkezOlkh|ryP NHS3OVdUSU6JRWK=
EW-22 MkXMS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoT0TWM2OD12MT64Olk4KM7:TR?= NGL3NIxUSU6JRWK=
NCI-H1755 M4XNcmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MULJR|UxRTRzLki3NlUh|ryP NFnGNXZUSU6JRWK=
KYSE-150 MUjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXTJR|UxRTR{LkG3PFIh|ryP MWnTRW5ITVJ?
CGTH-W-1 M4nk[mdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEm0dodKSzVyPUSyMlQ6PTVizszN M4PPNnNCVkeHUh?=
NB13 NXzHR|ROT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHm5VnNKSzVyPUSyMlYzOTdizszN MU\TRW5ITVJ?
SW872 MVfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NX3tb45jUUN3ME20Nk43OzNzIN88US=> Ml:1V2FPT0WU
KP-4 M{jlXWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVPJR|UxRTR{Lki4N|Ih|ryP M3:4ZnNCVkeHUh?=
HCC38 MXvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEjqenJKSzVyPUSyMlk3OThizszN NHS2[IFUSU6JRWK=
BB49-HNC NILZWolIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWXJR|UxRTR|LkKzOVYh|ryP MVTTRW5ITVJ?
CAL-62 MYXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NV;yOFl4UUN3ME20N{41ODJ6IN88US=> M4PEd3NCVkeHUh?=
NCI-H2029 NXPDfJJJT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHOxWXVKSzVyPUSzMlU2QDFizszN NVTF[3ViW0GQR1XS
M14 NHm0b4tIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXHJR|UxRTR2LkGzN|Ih|ryP NEPqTFZUSU6JRWK=
COLO-680N MWHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mn3GTWM2OD12ND6zN|kh|ryP MWnTRW5ITVJ?
Hs-578-T NFz0eIdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEnq[4pKSzVyPUS1MlAzQTRizszN M2TUOHNCVkeHUh?=
MSTO-211H MoLGS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWDJR|UxRTR3Lkm0PFIh|ryP NXzIfWx[W0GQR1XS
EW-1 NYnLXZFNT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIG0XW9KSzVyPUS1Mlk3QDlizszN M3m4Z3NCVkeHUh?=
SW948 MkTzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NV70b4hZUUN3ME20Ok41PDZ{IN88US=> MX7TRW5ITVJ?
NCI-H460 NFK3e|FIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NE\aUpBKSzVyPUS2MlUzOyEQvF2= MlnTV2FPT0WU
CAS-1 MofVS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGXHdHVKSzVyPUS2Mlc4ODFizszN NXLEUXhPW0GQR1XS
TGBC11TKB NV;OV3RtT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3Ho[WlEPTB;NEeuNVc4PyEQvF2= NIjiPXNUSU6JRWK=
HD-MY-Z M{i3ZWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1Ph[mlEPTB;NEiuO|g3KM7:TR?= M4ewOHNCVkeHUh?=
NCI-H226 M2\nUmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mlj4TWM2OD12OT63O|g2KM7:TR?= Mnu0V2FPT0WU
PA-1 MmnoS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGrac4NKSzVyPUS5Mlg{OzVizszN NWS2SYl{W0GQR1XS
LB2518-MEL NF33WmtIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFPPUHRKSzVyPUS5Mlg4OjNizszN NHm4UY9USU6JRWK=
A101D NFLVVGFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2XFfmlEPTB;NEmuPVQzPSEQvF2= M4jpT3NCVkeHUh?=
NCI-H2087 M1PGeGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1:wZ2lEPTB;NEmuPVY5OiEQvF2= MYTTRW5ITVJ?

... Click to View More Cell Line Experimental Data

Assay
Methods Test Index PMID
Western blot
CIP2A / p-AKT / AKT / PARP; 

PubMed: 25537503     


Time-dependent effects of afatinib on CIP2A, p-AKT and apoptosis-related proteins in the sensitive H358 and resistant H460 cells. Cells were exposed to 10 μM afatinib for up to 48 hours. Immunoblots were scanned and quantitated to determine the ratio of the level of CIP2A to actin. Data are mean ± SD. n = 3 for the different time intervals.

p-EGFR / p-IGF1R / p-ERK / p-AKT; 

PubMed: 26052929     


Effects of afatinib on EGFR and IGF1R Signaling Pathways. H1975 cells were treated with afatinib with various doses and cell lysates were subjected to Western blot analysis. Afatinib effectively inhibits p-EGFR and p-ERK while p-AKT was partially inhibited. IGF1R phosphorylation was increased upon afatinib treatment in H1975 cells.

25537503 26052929
Growth inhibition assay
Cell apoptosis; 

PubMed: 25537503     


Dose-dependent effects of afatinib on apoptosis. Data are mean ± SD. n = 3 for each concentration. *, p < 0.05, **, p < 0.01, vs. no afatinib. 

Cell viability; 

PubMed: 26515464     


A. MTS assay for Ba/F3 cells harboring EGFR exon 19 deletion and L858R. The proportional cell viability is shown. B. MTS assay for Ba/F3 cells harboring EGFR exon 19 deletion+T790M and L858R+T790M. The proportional cell viability is shown. C. MTS assay for Ba/F3 cells harboring wild type EGFR. The proportional cell viability is shown. Erlotinib, afatinib, osimertinib, and rociletinib were used as EGFR-TKIs. Error bars indicate standard deviation.

25537503 26515464
Immunofluorescence
p65; 

PubMed: 26317651     


Effects of different treatments on the nuclear translocation of the NF-κB subunit p65. A2780T cells were treated with 2.5 μM afatinib for 48 hours, or 10 μM PDTC for 2 hours. Subsequently, the NF-κB subunit p65 (red) was localized by immunofluorescence and a confocal microscopy. Nuclei were stained with DAPI (blue). Scale bar = 10 μM.

vacuoles; 

PubMed: 29713246     


Autophagy activation upon treatment with Afatinib and Sorafenib was validated using immunofluorescence in order to visualize a creation of autophagosomes; ×60 magnification. DMSO treatment was used as control. Green—autophagy vacuoles; Blue—Hoechst, nuclear staining. 

26317651 29713246
In vivo Daily oral administration of BIBW2992 at 20 mg/kg for 25 days results in dramatic tumor regression with a cumulative treated/control tumor volume ratio (T/C ratio) of 2%. Reduced phosphorylation of EGFR and AKT is confirmed by immunohistochemical staining of tissue sections. Therefore, like lapatinib and neratinib, BIBW2992 is a next generation tyrosine kinase inhibitor (TKI) that inhibits human epidermal growth factor receptor 2 (Her2) and epidermal growth factor receptor (EGFR) kinases irreversibly. BIBW2992 is not only active against EGFR mutations targeted by first generation TKIs like Erlotinib or Gefitinib, but also against those insensitive to these standard therapies. [1]

Protocol

Kinase Assay:

[1]

+ Expand

In vitro kinase activity assays:

The wild type tyrosine kinase domain of the human EGFR as well as that of the EGFR L858R/T790M double mutant are fused to Glutathione-S-transferase (GST), and extracted. Enzyme activity is then assayed in the presence of the inhibitor BIBW2992, serially diluted in 50% DMSO. A random polymer pEY (4:1) is used as substrate and biotinylated pEY (bio-pEY) is added as a tracer substrate. The kinase domain of HER2 is cloned using the baculovirus system and extracted similarly to that of EGFR kinase. Details of assays for EGFR, HER2, SRC, BIRK and VEGFR2 kinase activity are available in Supplementary information.
Cell Research:

[1]

+ Expand
  • Cell lines: NSCLC cells
  • Concentrations: 0-10 μM
  • Incubation Time: 1 hour
  • Method:

    1 × 104 NSCLC cells are transferred into each well of a 96-well plate and cultured overnight in serum-free media for the EGFR phosphorylation assay. After addition of BIBW2992 on the next day, the plates are incubated at 37 °C for 1 hour. EGF-stimulation is done using 100 ng/mL for 10 min at room temperature. Cells are washed with ice cold PBS, extracted with 120 μL HEPEX buffer per well and shaken at room temperature for 1 hour. In all 2 × 104 cells per well is used for the HER2 phosphorylation assay. Streptavidin precoated plates are coated with anti-EGFR-biotin at 1:100 dilution in blocking buffer and c-erb2/HER2 oncoprotein Ab-5(Clone N24)-Biotin. Cell extracts is then transferred to the antibody-coated wells and incubated at room temperature for 1 hour. Extinction is measured at 450 nm.


    (Only for Reference)
Animal Research:

[1]

+ Expand
  • Animal Models: Athymic NMRI-nu/nu female mice
  • Formulation: In 0.5% methocellulose-0.4% polysorbate-80 (Tween 80)
  • Dosages: 20 mg/kg
  • Administration: Oral administration
    (Only for Reference)

Solubility (25°C)

In vitro DMSO 97 mg/mL (199.61 mM)
Ethanol 15 mg/mL (30.86 mM)
Water Insoluble
In vivo Add solvents to the product individually and in order(Data is from Selleck tests instead of citations):
2% DMSO+30% PEG 300+5% Tween 80+ddH2O
For best results, use promptly after mixing.
10mg/mL

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 485.94
Formula

C24H25ClFN5O3

CAS No. 439081-18-2
Storage powder
in solvent
Synonyms N/A

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

  • Mass
    Concentration
    Volume
    Molecular Weight

*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1
    V1
    C2
    V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT03878524 Not yet recruiting Breast Cancer|Prostate Cancer|Pancreatic Cancer|Acute Myelogenous Leukemia OHSU Knight Cancer Institute|Oregon Health and Science University|Prospect Creek Foundation March 14 2019 Phase 1
NCT03878524 Not yet recruiting Breast Cancer|Prostate Cancer|Pancreatic Cancer|Acute Myelogenous Leukemia OHSU Knight Cancer Institute|Oregon Health and Science University|Prospect Creek Foundation March 14 2019 Phase 1
NCT03827070 Recruiting Non Small Cell Lung Cancer Center Trials & Treatment Europe|Center Trials & Treatment March 5 2019 Phase 1
NCT03827070 Recruiting Non Small Cell Lung Cancer Center Trials & Treatment Europe|Center Trials & Treatment March 5 2019 Phase 1
NCT03727724 Active not recruiting Carcinoma Non-Small-Cell Lung The Netherlands Cancer Institute|Boehringer Ingelheim|Merck Serono International SA December 4 2018 Phase 2
NCT03727724 Active not recruiting Carcinoma Non-Small-Cell Lung The Netherlands Cancer Institute|Boehringer Ingelheim|Merck Serono International SA December 4 2018 Phase 2

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

  • * Indicates a Required Field

Frequently Asked Questions

  • Question 1:

    What’s the recommendation about reconstitution of the compound for in vivo animal study?

  • Answer:

    For in vivo experiment of afatinib, we recommend 0.5% methylcellulose/0.2% Tween 80 as vehicle.

EGFR Signaling Pathway Map

EGFR Inhibitors with Unique Features

Related EGFR Products4

Tags: buy Afatinib (BIBW2992) | Afatinib (BIBW2992) supplier | purchase Afatinib (BIBW2992) | Afatinib (BIBW2992) cost | Afatinib (BIBW2992) manufacturer | order Afatinib (BIBW2992) | Afatinib (BIBW2992) distributor
×
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID