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4-Vinylcyclohexene dioxide

Name: 4-Vinylcyclohexene dioxide
Brand: Selleck Chemicals
SKU: E0024
Availability: InStock
Rating: 5 (1 reviews)

Cat.No.E0024

4-Vinylcyclohexene dioxide (Vinylcyclohexene dioxide, VCD) is a chemical used to induce menopause and decrease estrogen production. This compound is used as a crosslinking agent for the production of epoxy resins.

Chemical Structure

Molecular Weight: 140.18

Jump to Mechanism of Action Solubility Chemical Information, Storage & Stability

Quality Control

Batch: Purity: 100.00%

100.00

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Chemical Information, Storage & Stability

Molecular Weight	140.18	Formula	C₈H₁₂O₂	Storage (From the date of receipt)	2 years 4°C liquid
CAS No.	106-87-6	--		Storage of Stock Solutions	1 year-80°Cin solvent 1 month-20°Cin solvent
Synonyms	Vinylcyclohexene dioxide, VCD			Smiles	C1CC2OC2CC1C3CO3

Solubility

In vitro
Batch:

Molarity Calculator

Mass	Concentration	Volume	Molecular Weight
Mass value Mass unit	Concentration value Concentration unit	Volume value Volume unit	Molecular weight (g/mol)

Dilution Calculator Molecular Weight Calculator

In vivo batch selection In vivo Batch:
Clear solution	5%DMSO 1 40%PEG300 2 5%Tween80 3 50%ddH2O Validated by Selleck labs. Should you need adjustments to this formulation, contact our sales team for custom testing.	5.000mg/ml (35.67mM)	Taking the 1 mL working solution as an example, add 50 μL of 100 mg/ml clarified DMSO stock solution to 400 μL of PEG300, mix evenly to clarify it; add 50 μL of Tween80 to the above system, mix evenly to clarify; then continue to add 500 μL of ddH2O to adjust the volume to 1 mL. The mixed solution should be used immediately for optimal results.
Clear solution	5% DMSO 1 95% Corn oil Validated by Selleck labs. Should you need adjustments to this formulation, contact our sales team for custom testing.	2.500mg/ml (17.83mM)	Taking the 1 mL working solution as an example, add 50 μL of 50 mg/ml clear DMSO stock solution to 950 μL of corn oil and mix evenly. The mixed solution should be used immediately for optimal results.

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg

Average weight of animals: g

Dosing volume per animal: μL

Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO

% Tween 80

% ddH₂O

% DMSO

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Mechanism of Action

References	[1] https://www.ncbi.nlm.nih.gov/books/NBK507526/

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2024-05-22)

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
NCT06173115	Recruiting	Severe Aortic Stenosis	Second Affiliated Hospital School of Medicine Zhejiang University	October 20 2023	Not Applicable
NCT05335525	Recruiting	Vascular Closure\|Endovascular Procedure\|Hemostasis\|Peripheral Vascular Disease\|Femoral Artery	Terumo Europe N.V.\|Terumo Medical Corporation	September 30 2022	--
NCT04656951	Recruiting	Multiple Myeloma	University of Cologne\|Janssen-Cilag G.m.b.H	June 1 2021	Phase 2
NCT04459208	Completed	Aortic Valve Stenosis	Helios Health Institute GmbH	June 26 2020	Not Applicable

Tech Support

Handling Instructions

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