Home GPCR & G Protein Prostaglandin Receptor modulator 1-Methylnicotinamide chloride For research use only.

1-Methylnicotinamide chloride

Synonyms: 1-MNA, 3-Carbamoyl-1-methylpyridin-1-ium chloride, Trigonellamide chloride

1-Methylnicotinamide (1-MNA, 3-Carbamoyl-1-methylpyridin-1-ium, Trigonellamide) chloride is an active endogenous metabolite of nicotinamide that exhibits anti-inflammatory and anti-thrombotic activities. 1-Methylnicotinamide enhances tumor vasculature formation and markedly increases prostacyclin (PGI2) generation.

1-Methylnicotinamide chloride Chemical Structure

1-Methylnicotinamide chloride Chemical Structure

CAS: 1005-24-9

Selleck's 1-Methylnicotinamide chloride has been cited by 1 publication

Purity & Quality Control

Batch: Purity: 99.94%
99.94

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Biological Activity

Description

1-Methylnicotinamide (1-MNA, 3-Carbamoyl-1-methylpyridin-1-ium, Trigonellamide) chloride is an active endogenous metabolite of nicotinamide that exhibits anti-inflammatory and anti-thrombotic activities. 1-Methylnicotinamide enhances tumor vasculature formation and markedly increases prostacyclin (PGI2) generation.
Targets
PGI2 [1]
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT00685737 Completed
Hyperlipidemia
Pharmena North America
 December 2007 Phase 1

Chemical Information & Solubility

Molecular Weight 172.61 Formula

C7H9ClN2O
CAS No. 1005-24-9 SDF --
Smiles [Cl-].C[N+]1=CC=CC(=C1)C(N)=O
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

Water : 35 mg/mL

DMSO : Insoluble ( Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : Insoluble


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In vivo
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Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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