1-Methylnicotinamide chloride

Catalog No.S3346 Synonyms: 1-MNA, 3-Carbamoyl-1-methylpyridin-1-ium chloride, Trigonellamide chloride

For research use only.

1-Methylnicotinamide (1-MNA, 3-Carbamoyl-1-methylpyridin-1-ium, Trigonellamide) chloride is an active endogenous metabolite of nicotinamide that exhibits anti-inflammatory and anti-thrombotic activities. 1-Methylnicotinamide enhances tumor vasculature formation and markedly increases prostacyclin (PGI2) generation.

1-Methylnicotinamide chloride Chemical Structure

CAS No. 1005-24-9

Selleck's 1-Methylnicotinamide chloride has been cited by 1 Publication

Purity & Quality Control

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Biological Activity

Description

1-Methylnicotinamide (1-MNA, 3-Carbamoyl-1-methylpyridin-1-ium, Trigonellamide) chloride is an active endogenous metabolite of nicotinamide that exhibits anti-inflammatory and anti-thrombotic activities. 1-Methylnicotinamide enhances tumor vasculature formation and markedly increases prostacyclin (PGI2) generation.

Targets
PGI2 [1]

Protocol (from reference)

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight 172.61
Formula

C7H9ClN2O

CAS No. 1005-24-9
Storage 3 years -20°C powder
2 years -80°C in solvent

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Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT00685737 Completed Drug: 1-MNA|Drug: Placebo Hyperlipidemia Pharmena North America December 2007 Phase 1

(data from https://clinicaltrials.gov, updated on 2022-08-01)

Tech Support

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Handling Instructions

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