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OGG1

Other DNA Damage/DNA Repair Related Inhibitors

HDAC PARP WRN Sirtuin Topoisomerase Telomerase DNA/RNA Synthesis MTH1 DNA alkylator High-mobility Group
Cat.No. Product Name Information Product Use Citations Product Validations
S8913 TH5487 TH5487 is a selective active-site inhibitor of 8-oxoguanine DNA glycosylase 1 (OGG1) with IC50 of 342 nM.
bioRxiv, 2025, 2025.06.05.658156
bioRxiv, 2025, 2025.06.05.658156
PLoS Pathog, 2024, 20(10):e1012616
S9905 SU0268 SU0268 is a potent and specific inhibitor of 8-Oxoguanine DNA glycosylase 1 (OGG1), with the IC50 of 0.059 μM.
Frontiers in Oncology, 2022, 888810
Front Oncol, 2022, 12:888810
S0841 OGG1-IN-08 OGG1-IN-08 (O8 OGG1 Inhibitor-Bio-X) is a potent inhibitor of 8-oxoguanine DNA glycosylase-1 (OGG1) with IC50 of 0.22 μM. This compound decreases both the glycosylase and lyase activities of OGG1.
E1277 TH10785 TH10785 controls the catalytic activity mediated by a nitrogen base within molecular structure of cells and increases 8-oxoguanine DNA glycosylase 1 (OGG1) recruitment and repair of oxidative DNA damage.