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NPC1L1

Other Metabolism Related Inhibitors

Dehydrogenase Transferase DPP Aminopeptidase Procollagen C Proteinase P450 (e.g. CYP17) Phospholipase (e.g. PLA) Factor Xa PDE DHFR
Cat.No. Product Name Information Product Use Citations Product Validations
S3798 L-Citrulline L-citrulline is a substance called a non-essential amino acid that is used as a sports performance and cardiovascular health supplement.
E8028 FGH10019 FGH10019 is a novel sterol regulatory element-binding protein (SREBP) inhibitor with IC50 of 1 μM.
S1655 Ezetimibe (SCH-58235) Ezetimibe (SCH-58235) is a potent, selective, cholesterol absorption inhibitor that is used to lower cholesterol.
J Med Chem, 2025, 68(2):1179-1194
Toxicol Lett, 2025, 406:31-37
J Immunother Cancer, 2024, 12(11)e009805
Verified customer review of Ezetimibe (SCH-58235)
S8284 Fatostatin HBr Fatostatin HBr is an inhibitor of sterol regulatory element binding protein (SREBP). It impairs the activation of SREBP-1 and SREBP-2.
Cancer Commun (Lond), 2025, 10.1002/cac2.70038
Cell Commun Signal, 2025, 23(1):438
ACS Omega, 2024, 9(47):47042-47051
S6418 PF 429242 PF 429242 is known as a S1P inhibitor with an IC50 of 170 nM, showing no significant inhibition of trypsin, elastase, proteinase K, plasmin, kallikren, factor XIa, thrombin, or furin at concentrations up to 100 μM and only modest inhibition of urokinase (IC50 = 50 μM) and factor Xa (IC50 = 100 μM).
Cell Rep, 2023, 42(6):112586
Nat Commun, 2019, 11;10(1):4621
S9392 Praeruptorin B Praeruptorin B is an important compound isolated from Bai-hua Qian-hu and has been reported to exert multiple biochemical and pharmacological activities.praeruptorin B exerts lipid-lowering effects through inhibits SREBPs and could serve as a possible therapeutic option to improve hyperlipidemia and hyperlipidemia-induced comorbidities.
Nat Metab, 2021, 10.1038/s42255-021-00479-4