Home Immunology & Inflammation MIF

MIF

Other Immunology & Inflammation Related Inhibitors

CDK ROCK Wee1 Aurora Kinase Chk PLK Antimetabolites APC MPS1 Rho Myc
Cat.No. Product Name Information Product Use Citations Product Validations
S7732 ISO-1 ISO-1 (MIF Antagonist) is an inhibitor of MIF (Macrophage migration inhibitory factor) D-dopachrome tautomerase activity with an IC50 of ~7 μM.
EMBO J, 2024, 43(8):1519-1544
Mol Neurobiol, 2024, 61(12):10481-10499
Mol Neurobiol, 2024, 10.1007/s12035-024-04207-3
S2643 4-IPP 4-IPP (4-Iodo-6-phenylpyrimidine) is an irreversible inhibitor of macrophage migration inhibitory factor (MIF) and a specific suicide substrate for MIF. This compound can inhibit receptor activator of NF-κB ligand (RANKL)-induced osteoclastogenesis and potentiate osteoblast-mediated mineralization and bone nodule formation in vitro.
Mol Oncol, 2018, 12(8):1398-1409
SNU Open Repository, 2018, None
S-Space, 2018, N/A
S0539 BTZO-1 BTZO-1 binds to macrophage migration inhibitory factor (MIF) with Kd of 68.6 nM. This compound activats antioxidant response element (ARE)-mediated gene expression and suppresses oxidative stress-induced cardiomyocyte apoptosis in vitro.
S5609 Chicago Sky Blue 6B Chicago Sky Blue 6B (Direct Blue 1, Pontamine sky blue) is a counterstain for background autofluorescence in fluorescence and immunofluorescence histochemistry. It is an inhibitor of macrophage migration inhibitory factor (MIF) with an IC50 of 0.81 μM.