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G-quadruplex

G-quadruplex Products

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  • G-quadruplex Modulator (1)
  • New G-quadruplex Products
Catalog No. Product Name Information Product Use Citations Product Validations
S7444 Pyridostatin Trifluoroacetate Salt Pyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer with Kd of 490 nM in a cell-free assay, which targets a series of proto-oncogenes.
Nucleic Acids Res, 2025, 53(7)gkaf301
Cell Rep, 2025, 44(5):115706
Nucleic Acids Res, 2024, gkae785
E8172New Pyridostatin Pyridostatin (RR82) is a highly selective small molecule that stabilizes telomeric DNA G-quadruplex with a Kd of 490 nM, promoting their folding and inducing dysfunctional telomeres by uncapping POT1 and activating DNA damage signaling. It also modulates gene expression, reducing SRC protein levels and SRC-dependent motility in breast cancer cells, contributing to its anti-proliferative effects.
S7444 Pyridostatin Trifluoroacetate Salt Pyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer with Kd of 490 nM in a cell-free assay, which targets a series of proto-oncogenes.
Nucleic Acids Res, 2025, 53(7)gkaf301
Cell Rep, 2025, 44(5):115706
Nucleic Acids Res, 2024, gkae785
E8172New Pyridostatin Pyridostatin (RR82) is a highly selective small molecule that stabilizes telomeric DNA G-quadruplex with a Kd of 490 nM, promoting their folding and inducing dysfunctional telomeres by uncapping POT1 and activating DNA damage signaling. It also modulates gene expression, reducing SRC protein levels and SRC-dependent motility in breast cancer cells, contributing to its anti-proliferative effects.

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Tags: G-quadruplex inhibitor|G-quadruplex agonist|G-quadruplex activator|G-quadruplex inducer|G-quadruplex antagonist|G-quadruplex signaling pathway|G-quadruplex assay kit