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CPT

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Dehydrogenase Transferase DPP Aminopeptidase Procollagen C Proteinase P450 (e.g. CYP17) Phospholipase (e.g. PLA) Factor Xa PDE DHFR

Isoform-selective Products

Cat.No. Product Name Information Product Use Citations Product Validations
S8244 Etomoxir sodium salt Etomoxir sodium salt ((R)-(+)-Etomoxir sodium salt) is an irreversible inhibitor of carnitine palmitoyltransferase-1 (CPT-1) on the outer face of the inner mitochondrial membrane. Etomoxir enhances palmitate-induced cell apoptosis.
J Clin Invest, 2025, e190215
Cell Commun Signal, 2025, 23(1):206
Cell Death Discov, 2025, 11(1):21
Verified customer review of Etomoxir sodium salt
E4787 Etomoxir Etomoxir ((R)-(+)-Etomoxir) is an irreversible, small-molecule inhibitor of carnitine palmitoyl-transferase 1a (CPT1a). It inhibits fatty acid oxidation (FAO) and may have potential in treating diabetes, inflammation, cancer and cardiac metabolic diseases.
Mol Cancer, 2025, 24(1):34
Cell Metab, 2025, 37(11):2233-2249.e9
J Clin Invest, 2025, 135(23)e182480
S6959 Perhexiline maleate Perhexiline maleate is a potent inhibitor of carnitine palmitoyltransferase 1 (CPT1) with IC50s of 77 μM and 148 μM for rat heart CPT1 and liver CPT1, respectively, and also inhibits carnitine palmitoyltransferase 2 (CPT2).
Cancer Cell, 2022, S1535-6108(22)00312-9
S2269 Baicalin Baicalin is an inhibitor of prolyl oligopeptidase and also is an allosteric activator of carnitine palmityl transferase 1 (CPT1). This compound reduces the expression of NF-κB.
Front Pharmacol, 2025, 16:1563194
Ecotoxicol Environ Saf, 2024, 275:116262
Chem Biol Interact, 2024, 387:110820
S9819 C75 C75 (4-Methylene-2-octyl-5-oxotetrahydrofuran-3-carboxylic acid), a more stable synthetic mimic of cerulenin, inhibits fatty-acid synthase (FAS/FASN) with an IC50 of 15.53 μM and has potential therapeutic effects in several cancer models. This compound is also a potent CPT1A activator.
Cell Death Differ, 2025, 10.1038/s41418-025-01524-5
Adv Sci (Weinh), 2024, 11(46):e2401311
PLoS Pathog, 2024, 20(5):e1012228