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AGEs

Other Metabolism Related Inhibitors

Dehydrogenase Transferase DPP Aminopeptidase Procollagen C Proteinase P450 (e.g. CYP17) Phospholipase (e.g. PLA) Factor Xa PDE DHFR
Cat.No. Product Name Information Product Use Citations Product Validations
S6415 Azeliragon (TTP488) Azeliragon (TTP488, PF-04494700) is an orally bioavailable small molecule that inhibits the receptor for advanced glycation endproducts (RAGE), which is an immunoglobulin-like cell surface receptor overexpressed in brain tissues of patients with AD.
Oncogene, 2025, 44(15):1051-1062
iScience, 2025, 28(8):113063
Circ J, 2025, 10.1253/circj.CJ-24-0878
S2422 Ipriflavone (Osteofix) Ipriflavone (7-Isopropoxyisoflavon) is used to inhibit bone resorption.
S8185 FPS-ZM1 FPS-ZM1 is a blood-brain-barrier permeant, non-toxic, tertiary amide compound which is a high affinity RAGE-specific inhibitor, blocking Aβ binding to the V domain of RAGE.
Circ J, 2025, 10.1253/circj.CJ-24-0878
Clin Immunol, 2024, 262:110178
Pharmacol Res, 2023, 192:106791
Verified customer review of FPS-ZM1
S3939 4'-Methoxyresveratrol 4-Methoxyresveratrol is a stibenoid found in the Chinese herb Gnetum cleistostachyum. 4'-Methoxyresveratrol alleviates AGE-induced inflammation through suppressing RAGE-mediated MAPK/NF-κB signaling pathway and NLRP3 inflammasome activation.