Guanylate Cyclase
Inhibitory Selectivity
Guanylate Cyclase Products
| Catalog No. | Information | Product Use Citations | Product Validations |
|---|---|---|---|
| S7958 |
Lificiguat (YC-1)Lificiguat (YC-1) is an nitric oxide (NO)-independent activator of soluble guanylyl cyclase(sGC) and an inhibitor of Hypoxia-inducible factor-1alpha (HIF-1alpha). |
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| S9796New |
ODQODQ (1H-ODQ) is a potent and selective inhibitor of soluble guanylyl cyclase (sGC, nitric oxide-activated enzyme) that enhances the pro-apoptotic effects of cisplatin in human mesothelioma cells. |
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| S4535 |
Methylene BlueMethylene Blue (Basic Blue 9, Tetramethylthionine chloride, methylthioninium chloride, CI-52015) is used as a dye in chromoendoscopy. It Inhibits tau filament formation with IC50 of 1.9μM. Also it inhibits soluble guanylyl cyclase. |
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| S5229 |
Isosorbide dinitrateIsosorbide Dinitrate (ISDN, Sorbide nitrate, Sorbidnitrate, Isordil, Nitrosorbide) is the dinitrate salt form of isosorbide, an organic nitrate with vasodilator activity. Isosorbide Dinitrate is a medication used for heart failure, esophageal spasms, and to treat and prevent chest pain from not enough blood flow to the heart. Isosorbide Dinitrate can converte to nitric oxide (NO), an active intermediate compound which activates the enzyme guanylate cyclase (atrial natriuretic peptide receptor A). |
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| S9693New |
VericiguatVericiguat (BAY1021189, Verquvo) is a potent, orally available and soluble guanylate cyclase (sGC) stimulator. |
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| S8128 |
BAY 41-2272BAY 41-2272 is a direct and NO-independent soluble guanylate cyclase (sGC) stimulator. |
||
| S8135 |
Riociguat (BAY 63-2521)Riociguat (BAY 63-2521) is an oral soluble guanylate cyclase (GC) stimulator, used in the treatment of ipulmonary hypertension. |
| Catalog No. | Information | Product Use Citations | Product Validations |
|---|---|---|---|
| S7958 |
Lificiguat (YC-1)Lificiguat (YC-1) is an nitric oxide (NO)-independent activator of soluble guanylyl cyclase(sGC) and an inhibitor of Hypoxia-inducible factor-1alpha (HIF-1alpha). |
||
| S9796New |
ODQODQ (1H-ODQ) is a potent and selective inhibitor of soluble guanylyl cyclase (sGC, nitric oxide-activated enzyme) that enhances the pro-apoptotic effects of cisplatin in human mesothelioma cells. |
||
| S4535 |
Methylene BlueMethylene Blue (Basic Blue 9, Tetramethylthionine chloride, methylthioninium chloride, CI-52015) is used as a dye in chromoendoscopy. It Inhibits tau filament formation with IC50 of 1.9μM. Also it inhibits soluble guanylyl cyclase. |
| Catalog No. | Information | Product Use Citations | Product Validations |
|---|---|---|---|
| S5229 |
Isosorbide dinitrateIsosorbide Dinitrate (ISDN, Sorbide nitrate, Sorbidnitrate, Isordil, Nitrosorbide) is the dinitrate salt form of isosorbide, an organic nitrate with vasodilator activity. Isosorbide Dinitrate is a medication used for heart failure, esophageal spasms, and to treat and prevent chest pain from not enough blood flow to the heart. Isosorbide Dinitrate can converte to nitric oxide (NO), an active intermediate compound which activates the enzyme guanylate cyclase (atrial natriuretic peptide receptor A). |
| Catalog No. | Information | Product Use Citations | Product Validations |
|---|---|---|---|
| S9693New |
VericiguatVericiguat (BAY1021189, Verquvo) is a potent, orally available and soluble guanylate cyclase (sGC) stimulator. |
| Catalog No. | Information | Product Use Citations | Product Validations |
|---|---|---|---|
| S8128 |
BAY 41-2272BAY 41-2272 is a direct and NO-independent soluble guanylate cyclase (sGC) stimulator. |
||
| S8135 |
Riociguat (BAY 63-2521)Riociguat (BAY 63-2521) is an oral soluble guanylate cyclase (GC) stimulator, used in the treatment of ipulmonary hypertension. |
