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Coenzyme Q10 (CoQ10)

Name: Coenzyme Q10 (CoQ10)
Brand: Selleck Chemicals
SKU: S2398
Availability: InStock
Rating: 5 (7 reviews)

Cat.No.S2398

Coenzyme Q10 (ubiquinone, ubidecarenone, coenzyme Q) is a component of the electron transport chain and participates in aerobic cellular respiration. Its solutions are unstable and should be fresh-prepared.

Chemical Structure

Molecular Weight: 863.34

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Quality Control

Batch: Purity: >97%

Cited in Nature Medicine for its top-tier quality
COA
NMR
Datasheet
SDS/MSDS

Cited in Nature Medicine for its top-tier quality
COA
NMR
Datasheet
SDS/MSDS

Cited in Nature Medicine for its top-tier quality
COA
NMR
Microanalysis

Why microanalysis?
Datasheet
SDS/MSDS

Cited in Nature Medicine for its top-tier quality
COA
NMR
Microanalysis

Why microanalysis?
Datasheet
SDS/MSDS

Cited in Nature Medicine for its top-tier quality
COA
NMR
Datasheet
SDS/MSDS

Related Targets	PROTAC Dyes Antineoplastic and Immunosuppressive Antibiotics ADC Cytotoxin Selection Antibiotics for Transfected Cell Antibiotics for Mammalian Cell Culture ADC Linker Molecular Glues Hydrotropic Agents Antibiotics for Plant Cell Culture
Other Others Inhibitors	Furimazine (PBI 3939) Guanidinoacetic acid Blebbistatin Polybrene (Hexadimethrine Bromide) Silibinin (NSC 651520) Palmitic acid Carbazochrome sodium sulfonate (AC-17) 4-Methylumbelliferone (4-MU) Sesamin Osthole

Solubility

In vitro
Batch:

DMSO : Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Water : Insoluble

Ethanol : Insoluble

Molarity Calculator

Mass	Concentration	Volume	Molecular Weight
Mass value Mass unit	Concentration value Concentration unit	Volume value Volume unit	Molecular weight (g/mol)

Dilution Calculator Molecular Weight Calculator

In vivo batch selection In vivo Batch:
Clear solution	5%4-Methylpyridine 1 95%Corn oil Validated by Selleck labs. Should you need adjustments to this formulation, contact our sales team for custom testing.	5.000mg/ml (5.79mM)	Taking the 1 mL working solution as an example, add 50 μL of 100 mg/ml clarified 4-Methylpyridine stock solution to 950 μL of corn oil and mix evenly. The mixed solution should be used immediately for optimal results.
Homogeneous suspension	CMC-NA	≥5mg/ml	Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg

Average weight of animals: g

Dosing volume per animal: μL

Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO

% Tween 80

% ddH₂O

% DMSO

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Molecular Weight	863.34	Formula	C₅₉H₉₀O₄	Storage (From the date of receipt)	3 years-20°Cpowder
CAS No.	303-98-0	Download SDF		Storage of Stock Solutions	Solutions are unstable. Prepare fresh or purchase small, pre-packaged sizes. Repackage upon receipt.

Read more about storage stability CAS number

Mechanism of Action

In vitro

Coenzyme Q10 (CoQ10) is a component of the electron transport chain and participates in aerobic cellular respiration, generating energy in the form of ATP. It is found naturally in the energy-producing center of the cell known as the mitochondria, as well as in the membranes of many organelles. Some other organelles that contain this compound include endoplasmic reticulum, peroxisomes, lysosomes, and vesicles. It also works as an antioxidant.

References

[1] https://pubmed.ncbi.nlm.nih.gov/11771674/

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2026-05-19)

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
NCT07234422	RECRUITING	Heart Failure	Netherlands Heart Institute	2026-05-04	PHASE3
NCT07668284	NOT_YET_RECRUITING	Prostate Cancer; Uterine Cancer; Cervical Cancer; Anal Cancer	University of Nebraska	2026-07-01	PHASE1; PHASE2
NCT06694727	RECRUITING	Heart Failure	Tor Biering-Sørensen	2025-09-30	PHASE3
NCT06962657	NOT_YET_RECRUITING	Toxicant Induced Chronic Multisymptom Illness and Associated Symptoms and Comorbidities	University of California, San Diego	2026-05-15	PHASE2
NCT07760506	NOT_YET_RECRUITING	Healthy Aging; Inflammaging; Metabolic Health; Quercetin; Coenzyme Q10	Applied Science & Performance Institute	2026-08
NCT06515184	RECRUITING	Gulf War Syndrome; Persian Gulf Syndrome; Mitochondrial Disorder, Respiratory Chain	University of California, San Diego	2024-09-13	PHASE3

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Handling Instructions

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