Vorinostat (SAHA, MK0683)

Catalog No.S1047 Synonyms: SAHA, MK0683, suberoylanilide hydroxamic acid

Vorinostat (SAHA, MK0683) Chemical Structure

Molecular Weight(MW): 264.3

Vorinostat (suberoylanilide hydroxamic acid, SAHA) is an HDAC inhibitor with IC50 of ~10 nM in a cell-free assay.

Size Price Stock Quantity  
In DMSO USD 191 In stock
USD 147 In stock
USD 220 In stock
Bulk Discount

Free Overnight Delivery on orders over $ 500
Next day delivery by 10:00 a.m. Order now.

Cited by 100 Publications

20 Customer Reviews

  • Differential effects of HDAC inhibitors on histone and tubulin acetylation. Immunofluorescence analysis of histone H3 (K9ac/K14ac) and tubulin acetylation in HeLa cells treated for 4 h with vehicle, SAHA (10 μM), tacedinaline (50 μM), PCI-24781 (20 μM. (a) Mapping of histone acetylation in K562 cells treated with HDAC inhibitors by LC-MS/MS. Cells were treated with TSA (10 μM), SAHA (5 μM), PCI-24781 (2 μM), tacedinaline (50 μM) for 6 h. Histones were extracted from cells and acetylated peptides were quantified after isobaric tagging.

    Nat Biotechnol 2011 29, 255-265. Vorinostat (SAHA, MK0683) purchased from Selleck.

    Activity of vorinostat in Jurkat and Peer T-ALL cell lines in an MTT cell viability assay. Cells were treated with increasing drug concentrations for 72 h. The data are plotted as the mean % of DMSO-treated control cells against the corresponding drug concentration. The error bars are the standard error. For each drug and cell line, 3-4 independent experiments were performed with 6 replicates at each drug concentration.

    Nature 2011 471, 235-9. Vorinostat (SAHA, MK0683) purchased from Selleck.

  • Western blot analysis of histone H3 acetylation in the spleen of untreated and vorinostat-treated hNF-E2 tg mice (n = 4 of each genotype).

    J Exp Med 2012 209, 35-50. Vorinostat (SAHA, MK0683) purchased from Selleck.

    SAHA down-regulates c-FLIP expression and increases the sensitivity of CaP cells to undergo apoptosis in the presence of bicalutamide (A) Bar graph illustrating the sub-G0/G1 cell population in 22Rv1 (left panel) and LNCaP (right panel) cells in the absence and presence of 10μM bicalutamide, administered as a single agent or in ombination with increasing concentrations of the HDAC inhibitor, SAHA. (B) Immunoblots demonstrating the single agent activity of bicalutamide or SAHA, or effect upon their combined administration on the expression of c-FLIP and/or the processing of PARP. Equal protein loading was confirmed by GAPDH. (C) Bar graph illustrating the effect of bicalutamide and SAHA upon the induction of caspase-8 or caspase-3/7 activity in 22Rv1 cells (left panel) and LNCaP cells (right panel). (D) Immunoblots characterizing the impact of SAHA and/or bicalutamide upon the induction of PARP cleavage, in the absence or presence of the pan-caspase inhibitor, ZIETD. ZIETD was incubated with the cells for 12 h prior to the experiment. All data points shown in (A) and (C) represent the mean ± S.E.M. value, calculated from four independent experiments.

    Clin Cancer Res 2012 18, 3822-33. Vorinostat (SAHA, MK0683) purchased from Selleck.

  • Analyses of efficacy, potency and IC50 of HDAC inhibitors point toward HDACs 1–3 as relevant candidates for beta cell protection. Ranking and raw data on ITF drugs (Table 3) and commercial HDAC inhibitors (Table 4) underlying the heat maps of Fig. 1 (A and B). The HDAC inhibitor compounds were tested using a HDAC activity kit and recombinant proteins to determine IC50 values on each individual HDAC (right part of the table). Each drug was further tested using Real-Time Cell Analysis (RTCA) to score their maximal effective concentration (ECmax) as well as the corresponding rescue percentage of cytokine treated INS-1 cells. The drugs were ranked according to % rescue. * DMSO alone controls were included in each experiment, but not shown here. The results indicate that the highest concentrations of DMSO used here (1:1,000) were slightly potentiating the proliferation of the cells. The effects observed in this group of compounds were ascribed to the DMSO.?

    Diabetologia 2012 55, 2421-2431. Vorinostat (SAHA, MK0683) purchased from Selleck.

    Proliferation o f HT29 and HCT116 cells after 48 h of butyrate or SAHA treatment. Proliferation measurements using the xCEL Ligence RTCA DP instrument (Roche) in cells treated with increasing doses of butyrate or SAHA, compared with control medium cells (0) (*P < 0.05). The mean ?SEM of three cell culture replicates is shown.

    Mol Carcinog 2012 52, 459-74. Vorinostat (SAHA, MK0683) purchased from Selleck.

  • Suberoylanilide hydroxyamic acid (SAHA) preserves CFP (+) expression in mouse optic nerves (MONs) from older mice. (a) CFP (+) mitochondria were longer and thicker in MONs from 12-month-old Thy-1 CFP mice (inset; scale bar = 2 μm). Oxygen–glucose deprivation (OGD) consistently reduced CFP pixel intensity in 12-month-old MONs despite longer and brighter CFP ( +) mitochondria (yellow arrows). (b) Blockade of AMPA/kain ate receptors with NBQX (30 μM), or pan-Histone deacetylase (HDAC) inhibition with SAHA (5 μM), effectively preserved CFP pixel intensity during OGD. The preservation of CFP (+) mitochondria correlates with protection of the CAP area during OGD and profound recovery.

    J Neurochem 2012 123 Suppl 2, 108-15. Vorinostat (SAHA, MK0683) purchased from Selleck.

    D and E, Regression of IL-13Ra 2-negative pancreatic tumors treated with SAHA and/or IL-13-PE. Mice were treated daily with i.p. injection of SAHA (25 mg/kg) from day 4 after tumor implantation for two weeks followed by i.t. injection of IL-13-PE (100 μ g/kg) from day 5 for two weeks. F and G, Regression of IL-13Ra 2-posotive pancreatic tumors (HS766T and MIA-PaCa2) treated with SAHA and/or IL-13-PE. The schedule of treatment was similar as in panel D and E. Statistical significances are shown by *: P < 0.05,†: P < 0.001.

    J Transl Med 2011 9, 37. Vorinostat (SAHA, MK0683) purchased from Selleck.

  • IL-13Rα2 expression is upregulated in pancreatic tumors but not in organs of mice after treatment with HDAC inhibi tor, SAHA. A, qRT-PCR of human IL-13Rα2 in implanted pancreatic tumors after SAHA and IL-13-PE treatment. Tumors were harvested next day after IL-13-PE treatment and total RNA extracted. Data shown is ratio of human IL-13Rα2/β-actin expression and multiplied by 1000 for convenience. Bars , SD of triplicate determinations. B, qRT-PCR of mouse IL-13Rα2 in mice organs after SAHA and IL-13-PE treatment. Tissues were harvested at the same time point as in panel A and total RNA extracted. Data shown is ratio of mouse IL-13Rα2/β-actin expression and multiplied by 100 for convenience. C, IHC of human IL-13Rα2 in implanted pancreatic tumors after SAHA and IL-13-PE treatment. D, IHC of mouse IL-13Rα2 in mice organs after SAHA and IL-13-PE treatment. Liver, brain, kidney, pancreas, lung and spleen were fixed for immunostaining of mouse IL-13Rα2 as visualized by Alexa555. Nucleus was counterstained by DAPI.

    J Transl Med 2011 9, 37. Vorinostat (SAHA, MK0683) purchased from Selleck.

    Vorinostat inhibits the tumor growth. NOD ⁄ SCID-B2m-/-mice were injected s.c. with 1×106 MyLa2059 cells into both flanks. When the mice had developed established palpable tumors treatment was initiated (day 1). The mice received either vehicle (black line) or 60 mg ⁄ kg vorinostat (grey line) i.p. five days a week. In total, there were four mice in the group receiving vehicle and three mice in the group receiving vorinostat. The length and width of the tumors were measured continuously until the experiment was terminated on day 20 post treatment initiation. The tumor volume was calculated using the formula V = (a×b2)/2, where a defines the length (mm) and b the width (mm) of the tumor. The histogram shows the average tumor volume per flank ± SEM. * denotes a significant difference (P < 0.05) in the average tumor volume per flank between mice treated with vehicle and vorinostat at the given time-point both by using a one-tailed two samples test with Welch, scorrection and a Mann-Whitney U test.

     

     

    Exp Dermatol 2010 19, 1096-1102. Vorinostat (SAHA, MK0683) purchased from Selleck.

  • SAHA induces the down-regulation of cFLIP expression and promotes TRAIL-mediated activation of a mitochondrial-operated apoptotic pathway. a BT-474 cells were treated as indicated in Fig. 1 and the cells were then harvested to analyse caspase-8, Bid, caspase-9, caspase-3 and PARP expression, using GAPDH as the protein loading control. b BT-474 cells were treated with SAHA for 8 h at the doses indicated and subsequently, the cells were harvested and the apoptosis-related proteins were analysed in western blots as described in the "Materials and Methods". The results shown are representative of at least three independent experiments

    Invest New Drugs 2012 30, 541-547. Vorinostat (SAHA, MK0683) purchased from Selleck.

    Treatment with SAHA sensitizes breast cancer cells to TRAILinduced apoptosis. BT-474 and MDA-MB-231 cells were incubated for 8 h with SAHA at the doses indicated. After this time, TRAIL (500 ng/ml) was added to some of the cultures for an additional 15 h. Apoptosis was measured as the percentage of cells with subG1 DNA content as described in the "Materials and methods". The results show the mean and S.E.M. of three independent experiments

    Invest New Drugs 2012 30, 541-547. Vorinostat (SAHA, MK0683) purchased from Selleck.

  • SAHA facilitates the Itch/AIP4-independent proteasomal degradation of cFLIP proteins in breast cancer cells. a BT-474 cells were treated with SAHA (5 μM) for 8 h in the presence or absence of the proteasome inhibitors MG132 or epoxomicin (at the doses indicated), and they were then harvested and the cFLIP content was analysed in western blots. b BT-474 cells were transfected with either the siRNA oligonucleotides targeting Itch/AIP4 or the non-targeting RNA oligonucleotide (scrambled) for 48 h as described in the "Materials and Methods". Subsequently, the cells were treated with SAHA (5 μM) for 8 h and then cFLIP and Itch/AIP4 expression was analysed in immunoblots

    Invest New Drugs 2012 30, 541-547. Vorinostat (SAHA, MK0683) purchased from Selleck.

    cFLIP down-regulation following SAHA treatment is responsible for the sensitization of breast cancer cells to TRAIL. a BT-474 cells were transfected with either different siRNAs directed against the cFLIP isoforms or the non-targeting RNA oligonucleotide (scrambled) as described in the "Materials and Methods". After 24 h, the cells were treated with TRAIL (500 ng/ml) for a further 15 h and apoptosis was then measured as the percentage of cells with subG1 DNA content. The results show the mean and S.E.M. of three independent experiments. To verify protein knockdown, cells were harvested 24 h after transfection and the cFLIP levels were assessed in immunoblots. b. BT-474 cells overexpressing Cflipl (pBABE-FLIPL) or control cells (pBABE) were treated with SAHA for 8 h at the doses indicated. After this time, TRAIL (500 ng/ml) was added to some cultures for 15 h. Apoptosis was measured as the percentage of cells with subG1 DNA content and the results show the mean and range of two independent experiments. Western blots show the cFLIP levels after SAHA treatment in pBABE and pBABE-FLIPL cells.

    Invest New Drugs 2012 30, 541-547. Vorinostat (SAHA, MK0683) purchased from Selleck.

  • (a) Western blot of whole cell extracts demonstrates SAHA and NaB treatment result in increased levels of acetylated histone H3 compared to vehicle controls. (b) Light micrographs of HDACi/vehicle treated cultures illustrate the paucity of neurospheres in HDACi-treated cultures. (c) Quantitative analysis confirms SAHA and NaB inhibit the formation of neurospheres (diameter ≥ 50 μm) and increase the prevalence of small cell clusters (≥ 4 cell, diameter < 50 μm). (d) Flow cytometry using LIVE/DEAD cell stain confirms SAHA and NaB are minimally toxic compared to vehicle controls (n = 3). Scale bar = 100 μm.

    BMC Neurosci 2011 12, 50. Vorinostat (SAHA, MK0683) purchased from Selleck.

    (a) EdU flow cytometry of live cell-gated adult mouse NSCs demonstrates SAHA (**p < 0.01) and NaB (***p < 0.001) significantly inhibit DNA synthesis. (b) Analysis of DNA content by flow cytometry reveals significant accumulation of adult mouse NSCs in G1phase of the cell cycle following SAHA (*p < 0.05) and NaB (*p < 0.05) treatment. (c) Correspondingly the proportion of cells in G2/M phase is significantly reduced following SAHA (*p < 0.05) and NaB (*p < 0.05) treatment. (d) Fluorescence micrographs of HDACi/vehicle treated adult NSCs pulse-labeled with EdU for flow cytometry. Scale bar = 50 μm. Statistical comparisons performed using one-way ANOVA with post hoc Newman-Keuls multiple comparison tests.

    BMC Neurosci 2011 12, 50. Vorinostat (SAHA, MK0683) purchased from Selleck.

  • (a) Immunofluorescence labeling of NeuN, GFAP and Olig2 cell fate markers reveals reduced expression of GFAP (*p < 0.001) and Olig2 (*p < 0.05) in adult mouse NSCs treated with SAHA for 48 hours under proliferation culture conditions and then induced to differentiate for 14 days in culture (two-way ANOVA with Bonferroni post-tests). (b) Western blot of β-catenin protein in nuclear and cytoplasmic fractions of adult mouse NSCs treated with HDACi/vehicle control under proliferation culture conditions. Gapdh and lamin A/C blots are included as loading controls. (c) SAHA and NaB do not significantly alter nuclear/cytoplasmic levels of β-catenin in adult mouse NSCs. Histogram of β-catenin Western blot signal intensities normalized to loading controls (n = 4).

    BMC Neurosci 2011 12, 50. Vorinostat (SAHA, MK0683) purchased from Selleck.

    Morphological changes and histone H3 phosphorylation of HB cells treated with a combination of VX-680 and SAHA. HUH6 and HepT1 were incubated with VX-680 (6 μM) and SAHA (0.5 μM). Nuclei diameter (a) and cell diameter (b) were determined 72 h later by DAPI staining and microscopy. Data represent mean±SD of the diameters from 20 cells in each experiment. (* Two-way ANOVA, Bonferroni test, p \0.05). c Western blot analysis on HUH6 and HepT1 cells were carried out with an anti-phospho-Histone H3 (Ser 10) antibody (p-H3) 24 h after incubation with VX-680 (10 μM), SAHA (0.2 μM) or a combination of both. Controls were left untreated. Western blot analysis showed a decrease in p–H3 after treatment with VX-680 ( lane 2 ) relative to controls ( lane 1 ) and an increase when SAHA was added ( lane 3 ). For the combination of VX-680 and SAHA (lane 4 ) no p-H3 was detected.

    Pediatr Surg Int 2012 28, 579-89. Vorinostat (SAHA, MK0683) purchased from Selleck.

  • Vorinostat promotes C2C12 differentiation.In the image, the red is the myotube indicating differentiation ,the blue is the nuclei.

     

     

    Dr. Akihiko Yoshimura of Akihiko Yoshimura. Vorinostat (SAHA, MK0683) purchased from Selleck.

    Western blot analysis of Acetyl-H3 and H3. 0-20μM SAHA was added.

     

     

    Dr. Zhang of Tianjin Medical University. Vorinostat (SAHA, MK0683) purchased from Selleck.

Purity & Quality Control

Choose Selective HDAC Inhibitors

Biological Activity

Description Vorinostat (suberoylanilide hydroxamic acid, SAHA) is an HDAC inhibitor with IC50 of ~10 nM in a cell-free assay.
Targets
HDAC [1]
(Cell-free assay)
~10 nM
In vitro

Vorinostat inhibits the activities of HDAC1 and HDAC3 with IC50 of 10 nM and 20 nM, respectively. Vorinostat also results in a marked hyperacetylation of histone H4. [1] Vorinostat inhibits the growth of three prostate cancer cell lines LNCaP, PC-3 and TSU-Pr1 at micromolar concentrations (2.5-7.5 μM), and induces dose-dependent cell death in LNCaP cells. [2] Vorinostat treatment in MCF-7 cells inhibits cell proliferation at an IC50 of 0.75 μM resulting in the accumulation of cells in the G1 and G2-M phase of the cell cycle. Vorinostat also induces differentiation in the estrogen receptor-negative cell line SKBr-3 and the retinoblastoma-negative cell line MDA-468. [3] Vorinostat treatment at 1 μM for 8 hours or more is sufficient to irreversibly induce apoptosis of human multiple myeloma (MM) cells. The gene expression profiles of Vorinostat treated MM cells are not hallmarked by global transcriptional activation, but by coordinated transcriptional changes of specific functional groups of genes such as cytokine-induced proliferative/survival signaling cascades, oncogenes-tumor suppressor genes, regulators of apoptosis, DNA synthesis-repair and cell cycle, and proteasome-ubiquitin function. [4]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
A20 NH:wWFRMcW6jc3WgRZN{[Xl? MYixJIg> M{HvNGROW09? NFjwR3BidnSrLVjERWMyKGGldHn2bZR6KHerdHigTWM2OCCxZjCwMlEyOiEQvF2= MVWxNVk3ODR6OR?=
Friend leukemic cell MXfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mn3qOVAh|ryP M12xc|czKGh? NGTnbYxFVVOR NF[0PFNKSzVyPUCuPVkh|ryP NVnVSFl2OTJzMEm5NVM>
K562 NYrye2pOU2mwYYPlJGF{e2G7 Mnz0OkBp NELvWphFVVOR M1i0cGlvcGmkaYTpc44hd2ZiaIXtZY4hcGm|dH;u[UBl\WGlZYT5cIF{\SBqbXn4eJVz\SCxZjDISGFEOSCjbnSgTGRCSzJrIIfpeIghUUN3MDDv[kAxNjBzIN88US=> Ml7ENVI1OTl|OEC=
HT1080 MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NW[zVnFvPzJiaB?= MlXPSG1UVw>? NILBZ25KSzVyPUKuOEDPxE1? MUOxNlI4ODF5NR?=
H1299 NGmwdZRMcW6jc3WgRZN{[Xl? NF\Y[Y8zOCCvaX6= NWH0d5BXTE2VTx?= NIXlWIVKdmirYnn0c5J6KGGldHn2bZR6KGGpYXnud5QhUESDQzDlcpp6dWVid3n0bEBKSzVyIH;mJFAvOTl2IN88US=> MVexOFUzOTR{Mh?=
H1299 NXTObGt{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXi3NkBp M2TIbWROW09? MVnJR|UxRTdwMkSg{txO NHzhV5gyPDV{MUSyNi=>
HeLa MmTNT4lv[XOnIFHzd4F6 MUWzNEBucW5? NUf2eJZbUW6qaXLpeI9zgSClb37j[Y51emG2aX;uJIFo[Wmwc4SgbIl{fG:wZTDk[YFk\XS7bHHz[UB4cXSqIFnDOVAhd2ZiMD6yPEDPxE1? M{\QVlE2PjB|OUS5
LOX-IMVI NFjCXZlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUPGWG9YPDhiaB?= M{jSN2lEPTB;MT6zJO69VQ>? M13vPVE2PzF3NEew
NCI-H226 MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWm0PEBp MVvJR|UxRTJwNjFOwG0> NIPvO4syPTdzNUS3NC=>
RXF-631L NHTKco5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGj6fo01QCCq Ml7aTWM2OD1{IN88US=> NFLNNXUyPTdzNUS3NC=>
SNB-78 MYXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mmf0OFghcA>? NUnGSHRGUUN3ME2xOkDPxE1? NUDVU5VOOTV5MUW0O|A>
St-4 NVXIWFVkT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUnPN|NzPDhiaB?= NWTIWZh6UUN3ME21MlIh|ryP MWCxOVcyPTR5MB?=
ARP1 Ml3ISpVv[3Srb36gRZN{[Xl? MVeyJO69VQ>? MX[2JIg> M3njZmlv\HWldHnvckBw\iCSMkHXRWYyKGenbnWg[ZhxemW|c3nvci=> NGHad40yPDd|NEiwOi=>
CEM NXfSVYczU2mwYYPlJGF{e2G7 M1Tze|EhcA>? MnzBSG1UVw>? M{Lne2lvcGmkaYTpc44hd2ZiSFTBR{B4cXSqIFnDOVAhd2ZiMD6zN{DPxE1? NWLhOWU4OTZ2MkCwOlQ>
HCT15 Mnf1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M17Vd|Q5KGh? NVfuUlBDT0l3ME2wMlgzKM7:TR?= NYf0Z2FxOTZ5MkOyNlc>
NCI-H23 M4q2UGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlHGOFghcA>? MUHHTVUxRTBwOUKg{txO MYexOlczOzJ{Nx?=
GM15850 MVnLbY5ie2ViQYPzZZk> MUOyMlUh|ryP MXq5OkBp MUHEUXNQ MmTITY5pcWKrdHnvckBw\iCKRFHDJIF{e2W|c3XkJIF{KGmwY4LlZZNmKGmwIHjpd5RwdmViSEOgcJl{cW6nIEG0JIFk\XS7bHH0bY9vKG:oIF\YUkBo\W6n M17rV|E3QTJzM{[3
GM15850 NVf6T5k{U2mwYYPlJGF{e2G7 M3vuV|IvPSEQvF2= NUPaU3lSQTZiaB?= NUjy[VhDTE2VTx?= NFvYNHNKdmirYnn0bY9vKG:oIFjERWMh[XO|ZYPz[YQh[XNiaX7jdoVie2ViaX6gbIl{fG:wZTDIOEBtgXOrbnWgOUBi[2W2eXzheIlwdiCxZjDGXG4h\2WwZR?= M1T5dFE3QTJzM{[3
GM15850 NH7hTnNMcW6jc3WgRZN{[Xl? M1T4c|IvPSEQvF2= NF7yVGQ6PiCq M1njV2ROW09? NFzEOJdKdmirYnn0bY9vKG:oIFjERWMh[XO|ZYPz[YQh[XNiaX7jdoVie2ViaX6gbIl{fG:wZTDIOEBtgXOrbnWgNVIh[WOndInsZZRqd25ib3[gSnhPKGenbnW= MYqxOlkzOTN4Nx?=
GM15850 MU\LbY5ie2ViQYPzZZk> NGPR[FYzNjVizszN NEW5XVI6PiCq MknNSG1UVw>? MVzJcohq[mm2aX;uJI9nKEiGQVOgZZN{\XO|ZXSgZZMhcW6lcnXhd4UhcW5iaHnzeI9v\SCKMzDsfZNqdmViOTDhZ4V1gWyjdHnvckBw\iCIWF6g[4Vv\Q>? NHLneFgyPjl{MUO2Oy=>
GM15850 MnmxT4lv[XOnIFHzd4F6 NFrBPIQzNjVizszN NHLMb5Q6PiCq MlrCSG1UVw>? M2rQUmlvcGmkaYTpc44hd2ZiSFTBR{Bie3Onc4Pl[EBieyCrbnPy[YF{\SCrbjDobZN1d26nIFi0JIx6e2mwZTC4JIFk\XS7bHH0bY9vKG:oIF\YUkBo\W6n MlHGNVY6OjF|Nke=
GM15850 NHT6ZYpMcW6jc3WgRZN{[Xl? M2S0c|IvPSEQvF2= NV7WbWE4QTZiaB?= M4qzWmROW09? NUDKV|hkUW6qaXLpeIlwdiCxZjDISGFEKGG|c3Xzd4VlKGG|IHnuZ5Jm[XOnIHnuJIhqe3SxbnWgTFQhdHm|aX7lJFE3KGGlZYT5cIF1cW:wIH;mJGZZViCpZX7l MoC2NVY6OjF|Nke=
U937 M3;PNmZ2dmO2aX;uJGF{e2G7 MUW1JO69VQ>? NG[3N5IzPCCq NITsXHFFVVOR MoXxR4VtdCCleXPs[UBienKnc4SgZpkh[WOldX31cIF1cW:wIHH0JHMwTzJxTTDwbIF{\Q>? NYnuWZl4OTdyMES3NVg>
H661 NVHScmhJT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NH;QXmc1QCCq M2[x[2lEPTB;MTFOwG0> NYj1[XVGOTdzNUewNFk>
U937 NE\1bFVHfW6ldHnvckBCe3OjeR?= MYG1JO69VQ>? MXeyOEBp NGDoNo9FVVOR MlP6TY5kemWjc3WgbY4hcGm|dH;u[UBJOyCjY3X0fYxifGmxbh?= MkjrNVc1PDd5NUC=
U937 NVLrZlk6TnWwY4Tpc44hSXO|YYm= M1nhVVEh|ryP Mk\lNlQhcA>? MXTEUXNQ MYrF[oZm[3Rib36gZYxxcGFidIXieYxqdiCjY3X0fYxifGmxbh?= NXzzdZhjOTd2NEe3OVA>
RAW264.7 MYfGeY5kfGmxbjDBd5NigQ>? Ml;KNVAh|ryP M3K1UFI1cA>? MXj3ZZRmeg>? M1TOXWlvcGmkaYTpc44hd2ZiTGDTMZN1cW23bHH0[YQhXE6IYXzwbIEheHKxZIXjeIlwdiC5aYToJGlEPTBib3[gNE44PiEQvF2= NHH2NZIyPzR5N{WxPC=>
RAW264.7 NYH0PVlxTnWwY4Tpc44hSXO|YYm= MmLENVAh|ryP NIfDeYUzPGh? Mmf2e4F1\XJ? MoCxTY5pcWKrdHnvckBw\iCOUGOtd5RqdXWuYYTl[EBPVyCycn;keYN1cW:wIIfpeIghUUN3MDDv[kAyNjh6IN88US=> Mk\WNVc1Pzd3MUi=
SC9 NG\Ye5VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYr2dZZ3PDhiaB?= NE\XXnpKSzVyPUCuOlA3KM7:TR?= M3fy[lE4PTB5MkG5
ST14A NV;xNYZ6TnWwY4Tpc44hSXO|YYm= NXPkVVRWPSCwTR?= NIn0TW44OiCq MULJcoNz\WG|ZTDpckBTTVOWL17SV2YhdVKQQTDlfJBz\XO|aX;u NVnxc3ZzOTd3NkW5PVM>
ST14A NUmzUpdWTnWwY4Tpc44hSXO|YYm= MYq1JI5O NUiwRlczPzJiaB?= MU\JcoNz\WG|ZTDpckBGOkZzIH3SUmEh\XiycnXzd4lwdg>? NIrwO3MyPzV4NUm5Ny=>
PANC1 MkH3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVSxJO69VQ>? MVLJR|UxRTBwNEWg{txO NIPFWJQyPzV6OEe0OC=>
PANC1 NYfPUG93TnWwY4Tpc44hSXO|YYm= MkSxNUDPxE1? MnOxNlQhcA>? M2XZfWlv[3KnYYPlJIlvKHB{MWfBSlEwS0mSMTDn[Y5mKGW6cILld5Nqd25? NX\YUVhMOTd3OEi3OFQ>
PANC1 NGHqN2pHfW6ldHnvckBCe3OjeR?= MYGxJO69VQ>? MmXNNlQhcA>? M4XrdWlv[3KnYYPlJIlvKHB{N3vpdFEh\2WwZTDlfJBz\XO|aX;u MofDNVc2QDh5NES=
PT45 NYTSNYlmT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1nC[2lEPTB;NDFOwG0> MXmxO|U5QDd2NB?=
ACHN MkLSS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmmzNlEhcA>? NWTNVIhpT0l3ME2wMlY2KM7:TR?= MkHJNVc3PjJ4ME[=
PC3 NWPZeVYzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnjsNlEhcA>? M1PtUmdKPTB;MD63NUDPxE1? M332R|E4PjZ{NkC2
A431 MVzDfZRwfG:6aXOgRZN{[Xl? NEPFfVA4OiCq NX3nNXljUUN3ME20MlIh|ryP M3joWlE4PjlzN{[z
Cal27 NVLq[XZOS3m2b4TvfIlkKEG|c3H5 MorlO|IhcA>? NXv0W3VtUUN3ME2zMlIh|ryP MkfhNVc3QTF5NkO=
CCRF-CEM NIjiXW1EgXSxdH;4bYMhSXO|YYm= Moq1O|IhcA>? M{LGUGlEPTB;MD64JO69VQ>? NV[4O3ZZOTd4OUG3OlM>
EOL1 NUTQcGNLS3m2b4TvfIlkKEG|c3H5 M1\4WlczKGh? NF3yb5dKSzVyPUGg{txO NVvicpFrOTd4OUG3OlM>
Hec-1-A Ml3SR5l1d3SxeHnjJGF{e2G7 NGHvS5Y4OiCq MnvITWM2OD1zIN88US=> Mn7uNVc3QTF5NkO=
HeLa M4P2UWtqdmG|ZTDBd5NigQ>? MmjRNVAh|ryP M4DLcVMxKG2rbh?= MYHEUXNQ NEfzZ29KdmirYnn0bY9vKG:oIILlZ49u[mmwYX70JGhFSUNzIIfpeIghUUN3MDDv[kAxNjB{IN88US=> NFfJRYkyPzZ7MUe2Ny=>
RKOp21 M4jhTGN6fG:2b4jpZ{BCe3OjeR?= NHnHR2o4OiCq MU\JR|UxRTFwN{[g{txO MVyxO|Y6OTd4Mx?=
Saos2 MVHDfZRwfG:6aXOgRZN{[Xl? NUX4Z|l5PzJiaB?= MlLJTWM2OD1{LkOg{txO MlX2NVc3QTF5NkO=
SK-OV-3 M{LRVWN6fG:2b4jpZ{BCe3OjeR?= MlLMO|IhcA>? MknsTWM2OD1{LkKg{txO MVGxO|Y6OTd4Mx?=
U87MG M{nLXGN6fG:2b4jpZ{BCe3OjeR?= NVS0OlFXPzJiaB?= NGS4UGNKSzVyPUGxJO69VQ>? NUPlUHZoOTd4OUG3OlM>
NUGC3 Mn\tS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWe1JO69VQ>? MV6yOEBp M1voXWdKPTB;Mj63PUDPxE1? NGHZXlAyPzlyNEi0Ny=>
CCD1059SK Ml\CS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEPibVdKSzVyPUSzMlUh|ryP NHq3S3gyQDJ2N{W1OC=>
HepG2 MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NH3MXVNKSzVyPUCuNFAxPiEQvF2= M{PERVE5OjR5NUW0
HT1080 NXrhU5VyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NV\sN4VGUUN3ME2wMlAxOjRizszN MmHLNVgzPDd3NUS=
SKBR3 NHvxTWxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MoroTWM2OD1yLkig{txO MUexPFI1PzV3NB?=
SNB78 MXvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUfFR|UxRTF4IN88US=> MlH3NVgzPDd3NUS=
SQ20B MmHoS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVuxVGNlUUN3ME2zJO69VQ>? MoPPNVgzPDd3NUS=
St4 NUjUSWEzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3HFcmVEPTB;NT6yJO69VQ>? NXfPdJdZOTh{NEe1OVQ>
MCF7 NWD1XpdlTnWwY4Tpc44hSXO|YYm= MmfnNVAh|ryP M4\uSFghcA>? M2TWTGROW09? Mmr0TY5lfWO2aX;uJI9nKHS3YoXsbY4hcHmyZYLhZ4V1gWyjdHnvci=> MXyxPFI3QTJ{Nh?=
HEK293 NUDmWlJjU2mwYYPlJGF{e2G7 MkLrNUBp Mk\NSG1UVw>? NVjad3lSUW6qaXLpeIlwdiCxZjDISGFEOSC5aYToJGlEPTBib3[gNE4xOyEQvF2= NYr2RoVLOTh|MEi1OlM>
HEK293 M{\5cWtqdmG|ZTDBd5NigQ>? NUPOUnpZOSCq NV3QSXN{TE2VTx?= NEXwNFBKdmirYnn0bY9vKG:oIFjERWM{KHerdHigTWM2OCCxZjCwMlA2PyEQvF2= NW\GV3h[OTh|MEi1OlM>
G401 MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYfwS25{PzJiaB?= MlXjSG1UVw>? M1PHOWlEPTB;MTFOwG0> NEHTdIgyQDN5MEO3Ny=>
HeLa M2nnWmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NX3Zc|ZbPzJiaB?= M4fUdGROW09? NYq0enlOUUN3ME2wMlQ3KM7:TR?= MnLONVg{PzB|N{O=
Human renal epithelial cell MkO3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmLJO|IhcA>? M3njd2ROW09? M1z1WGlEPTB;MUSg{txO Mk\RNVg{PzB|N{O=
U937 M4L5VmZ2dmO2aX;uJGF{e2G7 MVO1JO69VQ>? NYTJVYZtOjRiaB?= M2n4[2lv\HWldHnvckBw\iCqaYP0c45mKEh2IHj5dIVz[WOndInsZZRqd25? MYixPFM5OTJ|OB?=
U937 MnuzSpVv[3Srb36gRZN{[Xl? NWHGOFhtPSEQvF2= Mlr1NlQhcA>? M3m1Zmlv\HWldHnvckBw\iCjbIDoZUB1fWK3bHnuJIh6eGW{YXPleJlt[XSrb36= M4HEcVE5OzhzMkO4
U937 NX7Feo1XTnWwY4Tpc44hSXO|YYm= MX61JO69VQ>? MVSyOEBp M2PVfmlv\HWldHnvckBw\iCyMkGg[ZhxemW|c3nvci=> M2fWTFE5OzhzMkO4
U937 MYfGeY5kfGmxbjDBd5NigQ>? NUH6T|JEPSEQvF2= M4Dwc|I1KGh? MXHJcoR2[3Srb36gc4Yh[XCxcITvd4l{ NWX0clV{OTh|OEGyN|g>
U937 NXXQcGRDTnWwY4Tpc44hSXO|YYm= NIjzO4k2KM7:TR?= M2LaNlI1KGh? NVLZR5Y5UW6mdXP0bY9vKG:oIHfyZY52dG:leYTpZ{BlcW[oZYLlcpRq[XSrb36= Mk\WNVg{QDF{M{i=
U937 NXXuTpVoU2mwYYPlJGF{e2G7 M{\BbVUh|ryP MUGyOEBp M1TzN2lvcGmkaYTpc44hd2ZiaIXtZY4hUESDQ{G= NHLVNpgyQDN6MUKzPC=>
U937 MkjJT4lv[XOnIFHzd4F6 MofKOUDPxE1? NIm0TGQzPCCq MVLJcohq[mm2aX;uJI9nKGi3bXHuJGhFSUN2 MUGxPFM5OTJ|OB?=
HEK-TE MWjGeY5kfGmxbjDBd5NigQ>? MX:1JO69VQ>? NWS5SVlMPmh? NH\CUIpFVVOR NFHuSYJKdmO{ZXHz[UBqdiCqaYP0c45mKEh|IHHj[ZR6dGG2aX;u NEPaWWsyQDR|NEG0OC=>
HPDE6c7 Mn\JR5l1d3SxeHnjJGF{e2G7 MV21NEDPxE1? MVy3NkBp MX3EUXNQ NXrZV5V2UUN3ME2xMlMh|ryP NX7lenVIOTh2OUS0OlM>
Human microvascular epithelial cell M2LlT2N6fG:2b4jpZ{BCe3OjeR?= MkD4OVAh|ryP NXfTRowzPzJiaB?= NEftV3VFVVOR NX;2XYw3UUN3ME2xMlMh|ryP NULFWlBDOTh2OUS0OlM>
Hup T3 NWDuUGhWS3m2b4TvfIlkKEG|c3H5 MVG1NEDPxE1? M1LCZVczcA>? NE\vUG5FVVOR M4DrRmlEPTB;MD64JO69VQ>? NEnRV2UyQDR7NES2Ny=>
Mia Paca2 NXLHNIl3S3m2b4TvfIlkKEG|c3H5 M3TQXFUxKM7:TR?= MoHvO|Jp MoTMSG1UVw>? MY\JR|UxRTFwMTFOwG0> NG\jc2syQDR7NES2Ny=>
Panc 04.03 MYrDfZRwfG:6aXOgRZN{[Xl? NYDQTWZJPTBizszN MX:3Nog> MkHzSG1UVw>? MWfJR|UxRTFwMjFOwG0> NUDCOFNjOTh2OUS0OlM>
SU 86.86 NVfWT2FOS3m2b4TvfIlkKEG|c3H5 MoTGOVAh|ryP M3mzOFczcA>? NXHCTXRrTE2VTx?= NGXOfnVKSzVyPUGuN{DPxE1? Mn3oNVg1QTR2NkO=
HEK293 NFHLeVBMcW6jc3WgRZN{[Xl? MUmzJIg> MkXnTY5pcWKrdHnvckBw\iC{ZXPvcYJqdmGwdDDISGFEPiCneIDy[ZN{cW:wIIfpeIghUUN3MDDv[kAxNjBzOTFOwG0> MmeyNVg2PTh4Nkm=
HeLa NGG5OG9McW6jc3WgRZN{[Xl? NWr3W4J[OiCq M2LiN2lvcGmkaYTpc44hd2ZiboXjcIVieiCKRFHDJJdqfGhiSVO1NEBw\iByLkC4N{DPxE1? NXX6[mQ6OTh3NUi2Olk>
RAW264.7 MoXDSpVv[3Srb36gRZN{[Xl? NVTPUZZpOiEQvF2= NED2T4c{NjViaB?= NWrEb4lwTE2VTx?= NYLT[Ww1SW62aX3hcIFzcWGuIHHjeIl3cXS7IHHnZYlve3RiUHzhd41w\Gm3bTDmZYxkcXCjcoXtJIlv\mWldHXkJJdqfGhiSVO1NEBw\iByLkGxJO69VQ>? Ml7yNVg3PDR7Nkm=
NB4 NWjZRXR[PDiq MWDEUXNQ NXnDPXJOUUN3ME2wMlYh|ryP NH3ybHIyQDd{M{O0PS=>
HEK293 M2jPXWZ2dmO2aX;uJGF{e2G7 MWexNEDPxE1? M2jUT|I1KGh? MV3EUXNQ NUjUeoFySWO2aY\heIlwdiCxZjDtc5V{\SCZboSzZUB{cWewYXzpcoch\XiycnXzd4Vl M3m3N|E6ODJ{Nke1
HCT116 MYPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlPTO|Jp M4n0dGROW09? NWW5SXhVUUN3ME2wMlMyKM7:TR?= MWmxPVA5PDJ7NB?=
HeLa MWnLbY5ie2ViQYPzZZk> MViyJO69VQ>? NWD4d|FOOzBibXnu M33GSGROW09? M2j1S2lvcGmkaYTpc44hd2ZiSFTBR|IhcW5iaIXtZY4hUGWOYTDj[YxteyC5aYToJGlEPTBib3[gNE4yKM7:TR?= MlnUNVkxQDR{OUS=
IGROV1 Ml\tS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlTkO|IhcA>? MWDEUXNQ MYrJR|UxRTJwMjFOwG0> MWexPVA5PDJ7NB?=
IGROV1 MYPLbY5ie2ViQYPzZZk> NFTlNnA2KM7:TR?= NGq0V4czPCCq M2nVU2ROW09? MYHJcohq[mm2aX;uJI9nKEiGQVOgZZN{\XO|ZXSgZZMheDV|IHHj[ZR6dGG2aX;u NXHsXVBsOTlyOESyPVQ>
IGROV1 NUe1VWtGU2mwYYPlJGF{e2G7 NH;COFYyOCEQvF2= Ml\0OEBp M2j5[GROW09? NWTpVpdjUW6qaXLpeIlwdiCxZjDISGFEKGG|c3Xzd4VlKGG|IHjpd5RwdmVvSESgZYNmfHmuYYTpc44> NXTEPFJNOTlyOESyPVQ>
IGROV1 M{PlfGtqdmG|ZTDBd5NigQ>? NFLSdVIyOCEQvF2= MYe0JIg> NEPUXmVFVVOR M3jyVWlvcGmkaYTpc44hd2ZiSFTBR|Yh[XO|ZYPz[YQh[XNiYXzwbIEufHWkdXzpckBi[2W2eXzheIlwdg>? MofZNVkxQDR{OUS=
T24 NF3rdW1McW6jc3WgRZN{[Xl? NIfkRXE{KGh? NWPSeoo{UW6mdXP0bY9vKG:oIHjpd5RwdmViSEOgZYNmfHmuYYTpc44hf2m2aDDFR|UxKG:oIECuNVIh|ryP MWexPVA5PDN7NR?=
T24 M1zyNGtqdmG|ZTDBd5NigQ>? M1HmbVMhcA>? MWPJcoR2[3Srb36gc4Yh[WyyaHGgeJVjfWyrbjDhZ4V1gWyjdHnvckB4cXSqIFXDOVAhd2ZiMD6yOUDPxE1? NEnWWWgyQTB6NEO5OS=>
HeLa MlHMT4lv[XOnIFHzd4F6 MofrNVUhdWmw NWHZXG9FTE2VTx?= MXHJcohq[mm2aX;uJI9nKEiGQVO2JIZzd21iboXjcIVieiCneITyZYN1KHerdHigTWM2OCCxZjCwMlA5PTVizszN MlfoNVkxQTN6OES=
HeLa NHPafVVMcW6jc3WgRZN{[Xl? M4fqeVE2KG2rbh?= M{fPNWROW09? NGfNTmJKdmirYnn0bY9vKG:oIFjERWM5KG[{b32gcpVkdGWjcjDlfJRz[WO2IIfpeIghUUN3MDDv[kAyNjh4IN88US=> MU[xPVA6Ozh6NB?=
NCI-H69 M3LuNGN6fG:2b4jpZ{BCe3OjeR?= M4nPelczKGh? MnzGSG1UVw>? M{jvZWlEPTB;Mj6wOkDPxE1? MU[xPVA6Ozh6NB?=
SKMES1 MnTnR5l1d3SxeHnjJGF{e2G7 NXLiflJIPzJiaB?= NF3CZnFFVVOR Mne0TWM2OD1{LkSyJO69VQ>? Mn\vNVkxQTN6OES=
S2 Ml\FT4lv[XOnIFHzd4F6 NXK3XppGOC5zLUGwJO69VQ>? M4SwUVEhcA>? M1vmNGlvcGmkaYTpc44hd2ZiUHzhd41w\Gm3bTDmZYxkcXCjcoXtJGhFSUNzIHX4dJJme3OnZDD3bZRpKEmFNUCgc4YhOC5yNUmg{txO MWmxPVMyPzR3MB?=
SHSY5Y MUnLbY5ie2ViQYPzZZk> NFXtNFUyOCEQvF2= M3fk[|Q5KGh? NX\JT5hqTE2VTx?= NH\LRoxKdmirYnn0bY9vKG:oIFjERWMhf2m2aDDJR|UxKG:oIECuOUDPxE1? NUjUWm1KOTl|NESxO|U>
SHSY5Y NY\NepM6S3m2b4TvfIlkKEG|c3H5 NILafZQyOCEQvF2= M1rh[FQ5KGh? NFn2V5NFVVOR MljNTWM2OD1{IN88US=> NH7HeoUyQTN2NEG3OS=>
DMS114 MnzKS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlLzOFghcA>? MUTHTVUxRTJwOTFOwG0> M4jlXFE6PDF7MkC1
HBC5 NHu2UZpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlXtOFghcA>? NUnSZlU1T0l3ME2xO{DPxE1? NGTocWkyQTRzOUKwOS=>
SNB78 MlzxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NV7EOFRzPDhiaB?= NIj1dWZIUTVyPUG2JO69VQ>? NGPVbWoyQTRzOUKwOS=>
HeLa NE\iU2JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXnNZoNzPzJiaB?= NXmwWG1CTE2VTx?= NFTSOFJKSzVyPUCuOFYh|ryP NIXGeXIyQTR2MUi0Oi=>
BHK NUL5TGNoU2mwYYPlJGF{e2G7 MkfjOUDPxE1? M{LXZVI1KGh? NHS3[VZFVVOR M1u5fWlvcGmkaYTpc44hd2ZiSFTBR|ch\XiycnXzd4VlKGG|c3Xzd4VlKGG|IHnuZ5Jm[XOnIHnuJJBt[XOvYTDt[Y1jemGwZTDG[IVtfGF3MEigR2ZVWiCycn;0[Ylv MmjnNVk6PjZ5OEm=
CFBE41o- NGHUSY9McW6jc3WgRZN{[Xl? MWm1JO69VQ>? NX;KNJYyQCCq NGPIfVdFVVOR M4nzb2lvcGmkaYTpc44hd2ZiSFTBR{Bie3Onc4Pl[EBieyCqeYDldoFk\XS7bHH0bY9vKG:oIHjpd5RwdmViSEO= M2PmZ|E6QTZ4N{i5
CFBE41o- MUnLbY5ie2ViQYPzZZk> NHzxXGo2KM7:TR?= NYnQ[XZRPCCq Mne1SG1UVw>? NVzGPWY6UW6qaXLpeIlwdiCxZjDISGFEKGG|c3Xzd4VlKGG|IHnuZ5Jm[XOnIHnuJI12fGGwdDDG[IVtfGF3MEigR2ZVWiCycn;0[YlvKGyndnXs M{jkWVE6QTZ4N{i5
CFBE41o- NEjkcHhMcW6jc3WgRZN{[Xl? MUWxJO69VQ>? NHPZVJgyKGh? M2GzOGROW09? MoLvTY5pcWKrdHnvckBw\iCKRFHDJIF{e2W|c3XkJIF{KGmwY4LlZZNmKGmwIFPGWHIheHKxdHXpckBt\X[nbB?= MmmyNVk6PjZ5OEm=
Primary bronchial epithelial cell NUTMRW9PU2mwYYPlJGF{e2G7 Ml7KNUDPxE1? M2XNO|I1KGh? MkHUSG1UVw>? M1\BWmlvcGmkaYTpc44hd2ZiSFTBR|ch[XO|ZYPz[YQh[XNiaX7keYN1cW:wIH;mJI12fGGwdDDG[IVtfGF3MEigR2ZVWiCycn;0[YlvKGGyaXPhcEB{fXKoYXPlJIxw[2GuaYrheIlwdg>? NIXmTGoyQTl4Nke4PS=>
CFBE41o- M2XBVmtqdmG|ZTDBd5NigQ>? NFryTIoyKM7:TR?= M{HTUFUh\GG7cx?= M3XTXGROW09? Ml7YTY5pcWKrdHnvckBw\iCKRFHDO{Bie3Onc4Pl[EBieyCrbnPy[YF{\SCrbjDzeIFjcWyrenH0bY9vKG:oIF\k[Yx1[TVyODDDSnRTKHC{b4TlbY4> NGPtNZcyQTl4Nke4PS=>
CFBE41o- NV\vWoFtU2mwYYPlJGF{e2G7 NHi3e4IyKM7:TR?= NHjw[ZMzPCCq NWHuXnkxTE2VTx?= NGC2RnZKdmirYnn0bY9vKG:oIFjERWM4KGG|c3Xzd4VlKGG|IHnuZ5Jm[XOnIHnuJGZl\Wy2YUWwPEBETlSUIIDyc5RmcW5idILh[oZq[2urbne= M3jhZVE6QTZ4N{i5
CFBE41o- NHi1NnlMcW6jc3WgRZN{[Xl? M4XXUFUh|ryP MW[yOEBp NX;aSWpDTE2VTx?= NFLTc4ZKdmirYnn0bY9vKG:oIFjERWM4KGG|c3Xzd4VlKGG|IHnuZ5Jm[XOnIHnuJJJifGVib3[gcYF1fXKjdHnvckBw\iCFRmTSJJBzd3SnaX6geI8hcXS|IHfsfYNw\m:{bR?= M2jmT|E6QTZ4N{i5
CFBE41o- NVfJVXo6U2mwYYPlJGF{e2G7 MV61JO69VQ>? NEjsSmkzPCCq Ml3vSG1UVw>? NGL1WW9KdmirYnn0bY9vKG:oIFjERWM4KGG|c3Xzd4VlKGG|IHnuZ5Jm[XOnIHnuJJN1[WKrbHn0fUBw\iCIZHXseIE2ODhiQ1\UVkBxem:2ZXnu M4jlT|E6QTZ4N{i5
CFBE41o- MV\LbY5ie2ViQYPzZZk> NEi2NlU2KM7:TR?= MWCyOEBp NES4cVlFVVOR M1LpR2lvcGmkaYTpc44hd2ZiSFTBR|ch[XO|ZYPz[YQh[XNiY3;ydoVkfGmxbjDv[kBufXSjboSgSoRmdHSjNUC4JGNHXFJidILh[oZq[2urbnegeI8h[2WubDDzeZJn[WOnIHHzJIdtgWOxZn;ycS=> NGHyRnAyQTl4Nke4PS=>
Primary bronchial epithelial cell NFfYO|RMcW6jc3WgRZN{[Xl? MnnrOUDPxE1? MUSyOEBp NHLXb3lFVVOR NGPK[HFKdmirYnn0bY9vKG:oIFjERWMh[XO|ZYPz[YQh[XNiaX7keYN1cW:wIH;mJI12fGGwdDDG[IVtfGF3MEigR2ZVWiCycn;0[YlvKGGyaXPhcEB{fXKoYXPlJIxw[2GuaYrheIlwdg>? MoTlNVk6PjZ5OEm=
Primary bronchial epithelial cell MnHST4lv[XOnIFHzd4F6 NGj1SmsyKM7:TR?= M4H3NFk3KGh? NXewU4J6TE2VTx?= MXPJcohq[mm2aX;uJI9nKEiGQVO3JIF{e2W|c3XkJIF{KGmwY4LlZZNmKGmwIIPoc5J1KGOrcnP1bZQh[3W{cnXueJM> MVyxPVk3Pjd6OR?=
BxPC3 NYTrNnE4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4THdFczKGh? NGnpV|BKSzVyPUKuO{DPxE1? NHjZSo0zODF2M{e3PC=>
CAL27 NWDHTIV7T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVftdGNmPzJiaB?= MX\JR|UxRTNwN{Kg{txO MYiyNFE1Ozd5OB?=
Capan1 MkGwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVG3NkBp NGD6ellKSzVyPUeuN{DPxE1? MkDnNlAyPDN5N{i=
HCC827 NWnH[m1pT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MX63NkBp MkTDTWM2OD1zLkig{txO NU[1fFhTOjBzNEO3O|g>
LNCAP NW\6S4JFT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWP1[|hHPzJiaB?= M3PaXmlEPTB;MD61PEDPxE1? NIfTXpczODF2M{e3PC=>
NCI-H2122 NUXrb|A3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NELZSHY4OiCq NFP0TG5KSzVyPUeuOUDPxE1? NGnW[FgzODF2M{e3PC=>
NCI-H358 Mn[3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVXTOItsPzJiaB?= M4rjSmlEPTB;Mj61JO69VQ>? NYDZV2ZGOjBzNEO3O|g>
SCC15 MnLUS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NH;pfW44OiCq MXTJR|UxRTJwNEmg{txO Mn;UNlAyPDN5N{i=
SCC25 NE\kbIlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NILiVmc4OiCq MoTrTWM2OD1zLkmzJO69VQ>? MYKyNFE1Ozd5OB?=
SKHEP1 NVLuT3VQT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NV\Wd2ppPzJiaB?= NH7KN3JKSzVyPUOuOFYh|ryP NUm5e2JMOjBzNEO3O|g>
BJ MYnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MY[xNFAh|ryP NHq1NGE1QCCq Mmq1SG1UVw>? MoK0S5Jwf3SqIHnubIljcXSrb36gZZQhOC5yNTD0c{AyODBidV2= MX[yNFE1Ozh2MB?=
MUF M{PJ[2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXWxNFAh|ryP MWK0PEBp MYXEUXNQ NF;jd|ZIem:5dHigbY5pcWKrdHnvckBifCByLkC1JJRwKDFyMDD1US=> NGDreZUzODF2M{i0NC=>
Caco-2 M360fWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYexNFAh|ryP Mn\ROFhp NUnSepJSTE2VTx?= M160dmlEPTB;OD6xJO69VQ>? M2i0flIxOTR|OESw
Caco-2 MnXuT4lv[XOnIFHzd4F6 M2T3O|Uh|ryP NVj3SJgyPCCq NUDGXIpkTE2VTx?= MnfZTY5lfWO2aX;uJI9nKEiGQVOtcYVlcWG2ZXSgbIl{fG:wZTDhZ4V1gWyjdHnvckBKSzVyIH;mJFAvODN5IN88US=> NUfiboNoOjBzNEO4OFA>
Caco-2 NHLVSINMcW6jc3WgRZN{[Xl? MUCwMlMyPiCwTTD0c{A{OS54IN88US=> Mn3POEBp M{\sWGROW09? NGfmOXpGgCC4aY\vJIlvcGmkaYTpc44hd2ZiaIXtZY4hUESDQ{Gge4l1cCCLQ{WwJI9nKDBwMUG5JO69VQ>? NHTaUpMzODF2M{i0NC=>
Caco-2 NXL2OmpvU2mwYYPlJGF{e2G7 M4jzRlAvOzF4IH7NJJRwKDNzLk[g{txO NGjuc241KGh? MW\EUXNQ MmP5SZghfmm4bzDpcohq[mm2aX;uJI9nKGi3bXHuJGhFSUN|IIfpeIghUUN3MDDv[kAxNjF2NzFOwG0> MnTVNlAyPDN6NEC=
Caco-2 M{PJS2tqdmG|ZTDBd5NigQ>? MXm2MlMzKG6PIITvJFY{OiEQvF2= MWC0JIg> MlT5SG1UVw>? M2HUS2V5KH[rdn:gbY5pcWKrdHnvckBw\iCqdX3hckBJTEGFNTD3bZRpKEmFNUCgc4YhOTJwNjFOwG0> NFLaNHMzODF2M{i0NC=>
Caco-2 MWnLbY5ie2ViQYPzZZk> M1exdVYvOzJibl2geI8hPjN{IN88US=> NWjvVoxTPCCq MljTSG1UVw>? NE\WNotGgCC4aY\vJIlvcGmkaYTpc44hd2ZiaIXtZY4hUESDQ{ege4l1cCCLQ{WwJI9nKDRzIN88US=> NYTuNFdVOjBzNEO4OFA>
Caco-2 M1XLT2tqdmG|ZTDBd5NigQ>? MkHNNE4{OTZibl2geI8hOzFwNjFOwG0> NEDxRYM1KGh? NX\S[GliTE2VTx?= NHPBdYVGgCC4aY\vJIlvcGmkaYTpc44hd2ZiaIXtZY4hUESDQ{[= Ml3jNlAyPDN6NEC=
HepG2 MUnLbY5ie2ViQYPzZZk> MWO1JO69VQ>? M3;pOlZp M3KwVWROW09? NF;nfYxKdmS3Y4Tpc44hd2ZiSFTBR{1u\WSrYYTl[EBpcXO2b37lJIFk\XS7bHH0bY9v NXvIbGZ1OjBzNEO4OFA>
HepG2 MYDLbY5ie2ViQYPzZZk> MYe1JO69VQ>? MWe2bC=> MnPFSG1UVw>? MkTyTY5lfWO2aX;uJI9nKEiGQVOtcYVlcWG2ZXSgbIl{fG:wZTDofZBmemGlZYT5cIF1cW:w Mk\xNlAyPDN6NEC=
HepG2 MnHNT4lv[XOnIFHzd4F6 MVO1JO69VQ>? NUXOSFhpPmh? Mn;pSG1UVw>? MnrwTY5lfWO2aX;uJI9nKEiGQVOtcYVlcWG2ZXSgZYxxcGFvdIXieYxqdiCjY3X0fYxifGmxbh?= NW[5bmJzOjBzNEO4OFA>
HepG2 NVe1d5hnU2mwYYPlJGF{e2G7 Ml7IOUDPxE1? NFLFeWk3cA>? M{jMXGROW09? M1XNZ2lv\HWldHnvckBw\iCKRFHDMY1m\GmjdHXkJGg{N0h2IHjpd5RwdmViYXPleJlt[XSrb36= M3K5R|IxOTR|OESw
COLO205 NGP4bHhMcW6jc3WgRZN{[Xl? NV70OYNIOTBizszN MkPLNlQhcA>? M{mweWROW09? M3e2eWlvcGmkaYTpc44hd2ZiSFTBR|Eh[XO|ZYPz[YQh[XNiaX7keYN1cW:wIH;mJIhqe3SxbnWgTFMh[WOndInsZZRqd25id3n0bEBKSzVyIH;mJFIvOiEQvF2= NVHwR5B5OjB2NUGzO|g>
SCC4 MVvLbY5ie2ViQYPzZZk> MXixJO69VQ>? NHG0eXMzPGh? M2TIbWlvcGmkaYTpc44hd2ZiSFTBR{Bie3Onc4Pl[EBieyCrbnPy[YF{\SCrbjD0eYJ2dGmwIHHj[ZR6dGG2aX;u NXy0TI5COjB2NUKyNlU>
SCC4 NGf6dVhMcW6jc3WgRZN{[Xl? NH;LSGgyKM7:TR?= NH;kd3gzPGh? NETYSpRKdmirYnn0bY9vKG:oIFjERWMh[XO|ZYPz[YQh[XNiaX7jdoVie2ViaX6gbIl{fG:wZTDhZ4V1gWyjdHnvci=> NE\wNXMzODR3MkKyOS=>
SCC4 MWfGeY5kfGmxbjDBd5NigQ>? M1;jPFEh|ryP MUK1JI1qdg>? NXX6N3ZXSWexbnnzeEBi[3Srdnn0fUBifCCYRGKgZZN{\XO|ZXSgZZMhcW6mdXP0bY9vKG:oIFPZVFI1KGenbnWg[ZhxemW|c3nvci=> M4nyc|IxPDV{MkK1
NB4 NXe4W3V6TnWwY4Tpc44hSXO|YYm= NY\oPVE1PSEQvF2= M{DzWVI1KGh? NGTWW5ZFVVOR MYPD[YxtKGO7Y3zlJIFzemW|dDDhd5Nme3OnZDDhd{BqdmO{ZXHz[UBqdiCjY3P1cZVt[XSrb36gZZQheHKnLVexJJBp[XOn M3W4bVIxPDlzNESw
NB4 M1nI[mtqdmG|ZTDBd5NigQ>? NHXiVIc2KM7:TR?= Mn70NlQhcA>? MYHEUXNQ MYfJcohq[mm2aX;uJI9nKEiGQVOgZZN{\XO|ZXSgZZMhcW6lcnXhd4UhcW5iYXPleJlt[XSnIIT1ZpVtcW5ibHX2[Yw> MoPpNlA1QTF2NEC=
NB4 MV7GeY5kfGmxbjDBd5NigQ>? NUjLWFRQPSEQvF2= NX7IVlZCOjRiaB?= NGTTNGtFVVOR MVjJcoR2[3Srb36gc4YheDJzV1HGNU9EUVBzIHX4dJJme3Orb36= MmnqNlA1QTF2NEC=
NB4 MXXLbY5ie2ViQYPzZZk> M2\SSFUh|ryP NHzY[40zPCCq NInxSYtFVVOR M1LlRWlvcGmkaYTpc44hd2ZiSFTBR{Bie3Onc4Pl[EBieyCrbnPy[YF{\SCrbjDobZN1d26nIFizJIFk\XS7bHH0bY9v NULVWXM4OjB2OUG0OFA>
NUGC3 NXGzOYN6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkDIS2k2OD1{Lkm0JO69VQ>? M2LoPFIxQDVyOUex
A549 NEnuSJFHfW6ldHnvckBCe3OjeR?= NWLs[|RDPSEQvF2= MlnRN{Bp M1TRbGROW09? NVHtZYJxUW6mdXP0bY9vKG:oIHH1eI9xcGGpeTDpckBpfW2jbjDBOVQ6KGOnbHzzJIF{e2W|c3XkJIF{KGmwY4LlZZNmKGmwIFzDN2lK NIDwWJczODh3NUKwPC=>
HUT78 M{L1[Wdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnHrO|IhcA>? MofsSG1UVw>? Mk[zS2k2OD1yLkOg{txO MWmyNFg5PDJyOB?=
U937 Mn7oS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3HoXVczKGh? NI\zeHpFVVOR NIGzWY9IUTVyPUCuN|kh|ryP NH:1dXUzODh6NEKwPC=>
A431 MmrIR5l1d3SxeHnjJGF{e2G7 MXi3NkBp MnG5R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gRVQ{OSClZXzsd{BwfmW{ZYjwdoV{e2mwZzDFS2ZTKHerdHigTWM2OCCxZjC0MlIh|ryP NIrJUYUzOTB6ME[yPS=>
A549 M3zOWWN6fG:2b4jpZ{BCe3OjeR?= Ml;2O|IhcA>? NGHPdmZEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBCPTR7IHPlcIx{KG:4ZYLlfJBz\XO|aX7nJGhFSUNid3n0bEBKSzVyIH;mJFEvQCEQvF2= M1\OU|IyODhyNkK5
CAL27 NWjLdnZuS3m2b4TvfIlkKEG|c3H5 MVO3NkBp NWPT[JVMS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hS0GOMkegZ4VtdHNib4\ldoV5eHKnc4PpcochTUeIUjD3bZRpKEmFNUCgc4YhOy5{IN88US=> NUPpcldpOjFyOEC2Nlk>
HeLa MXrDfZRwfG:6aXOgRZN{[Xl? MnfFO|IhcA>? MXfDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDI[WxiKGOnbHzzJI93\XKneIDy[ZN{cW6pIFjERWMhf2m2aDDJR|UxKG:oIEGuOUDPxE1? NILPNIszOTB6ME[yPS=>
Sf21 NWC2SWlFU2mwYYPlJGF{e2G7 MWqzJIg> Ml3kTY5pcWKrdHnvckBw\iCIbHHnJJRi\2enZDDoeY1idiC{ZXPvcYJqdmGwdDDISGFEQCCneIDy[ZN{\WRid3n0bEBKSzVyIH;mJFEvOiEQvF2= MYGyNVA5ODZ{OR?=
SKBR3 NGnQfohEgXSxdH;4bYMhSXO|YYm= NH75bFI4OiCq MYTDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDTT2JTOyClZXzsd{BwfmW{ZYjwdoV{e2mwZzDISXIzKHerdHigTWM2OCCxZjCyMlYh|ryP NF\pUlQzOTB6ME[yPS=>
SKOV3 M{nIO2N6fG:2b4jpZ{BCe3OjeR?= MnLIO|IhcA>? Mk\aR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gV2tQXjNiY3XscJMhd3[ncnX4dJJme3OrbnegTGVTOiC5aYToJGlEPTBib3[gNk4zKM7:TR?= NFftcVQzOTB6ME[yPS=>
COR-L23 NWrqVJV{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUSxNEDPxE1? MVK3NkBp MkTUSG1UVw>? NVrifXo2T0l3ME2xMlEh|ryP NFrzeZgzOTB6ME[0Oy=>
DU145 NWLOUFZnT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NESxd5cyOCEQvF2= NUP0eZBMPzJiaB?= NWXsNlV6TE2VTx?= NIPyZlNIUTVyPUGuNFUh|ryP MX2yNVA5ODZ2Nx?=
LoVo MnXVS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUixNEDPxE1? MXS3NkBp MnzZSG1UVw>? NILS[VRIUTVyPUGuO{DPxE1? NGTCbY4zOTB6ME[0Oy=>
MCR5-SV2 NEL2c5dIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHX5[lIyOCEQvF2= NEXRTVM4OiCq MoLWSG1UVw>? NH3Ce|FIUTVyPUKuNUDPxE1? NYKyTmpxOjFyOEC2OFc>
HCT116 NHK1R|dMcW6jc3WgRZN{[Xl? NEL1e44{OCEQvF2= M3;lNFMxKGh? MkWySG1UVw>? MUPJcohq[mm2aX;uJI9nKEiGQVO2JIF{e2W|c3XkJIF{KGmwZIXjeIlwdiCxZjDhcJBp[S22dXL1cIlvKGGlZYT5cIF1cW:w NIDQUnYzOTB6ME[0Oy=>
HCT116 M3H1SmtqdmG|ZTDBd5NigQ>? MXGzNEDPxE1? MoX6N|AhcA>? NFu0WZBFVVOR MlfSTY5pcWKrdHnvckBw\iCKRFHDNUBie3Onc4Pl[EBieyCrbnT1Z5Rqd25ib3[gbIl{fG:wZTDIN2s6KGGlZYT5cIF1cW:w M2O1TVIyODhyNkS3
U937 MUjLbY5ie2ViQYPzZZk> M{fMNFUh|ryP M2T1PFI1KGh? M33aVGROW09? Mn7ETY5pcWKrdHnvckBw\iCqaYP0c45mKGGlZYT5cJRz[W6|ZnXyZZNmKGG|c3Xzd4VlKGG|IHnuZ5Jm[XOnIH;mJIFk\XS7bHH0bY9vKG:oIHjpd5RwdmViSEOgZZQhUzl? MYiyNVI6OjR7Mh?=
U937 NV7hcoNYU2mwYYPlJGF{e2G7 M376XlUh|ryP M33O[FI1KGh? MojMSG1UVw>? NHfZem5KdmirYnn0bY9vKG:oIHjpd5RwdmViYXPleJltfHKjboPm[ZJie2ViYYPz[ZN{\WRiYYOgbY5kemWjc3Wgc4Yh[WOndInsZZRqd25ib3[gbIl{fG:wZTDIN{BifCCNMUi= M1TpeFIyOjl{NEmy
U937 MXjLbY5ie2ViQYPzZZk> MWq1JO69VQ>? M4HMZVI1KGh? MUPEUXNQ MmXFTY5pcWKrdHnvckBw\iCqaYP0c45mKGGlZYT5cJRz[W6|ZnXyZZNmKGG|c3Xzd4VlKGG|IHnuZ5Jm[XOnIH;mJJBidi2jY3X0fYxifGWmIHjpd5RwdmViSESgcIV3\Wx? Mlj5NlEzQTJ2OUK=
U937 MlfrT4lv[XOnIFHzd4F6 NV7hXVE2PSEQvF2= M{TCWlE2KG2rbh?= MXrEUXNQ MVzJcohq[mm2aX;uJI9nKGirc4TvcoUh[WOndInseJJidnOoZYLhd4Uh[XO|ZYPz[YQh[XNiaX7jdoVie2Vib3[gbIl{fG:wZTDIN{Bi[2W2eXzheIlwdiCuZY\lcC=> MWWyNVI6OjR7Mh?=
A2780 MXvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2LHbFk3KGh? M4TzbmROW09? MoDnTWM2OD1zLk[yJO69VQ>? NV;kVVN3OjF4M{S0N|A>
COLO205 MUHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVy5UZdIQTZiaB?= MojPSG1UVw>? MVPJR|UxRTJwMUKg{txO M2r2c|IyPjN2NEOw
Hep3B NEi2U3BIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUS0PEBp M3ftXGROW09? M2jPVGdKPTB;MT6yNUDPxE1? NEHGOXQzOTdzMkG0Oi=>
GM11272 MVLGeY5kfGmxbjDBd5NigQ>? M4jm[FExOCCwTR?= MknsO|IhcA>? M2HucGROW09? NX7POIx[WmWjY4TpeoF1cW:wIH;mJG1mS3B{IH31eIFvfCCneIDy[ZN{cW:wIHH0JFExKHSxIEGwNEBvVQ>? NXPucWJbOjF6NEC3NVY>
CFBE41o NEXucWlMcW6jc3WgRZN{[Xl? MWm1JO69VQ>? NWjSWosxTE2VTx?= MoPpSI94diC{ZXf1cIF1cW:wIH;mJGhFSUN5IHH0JFAvOiC2bzC1JJVO NIHIU2MzOTl6NEm1PC=>
CFBE41o M3XCOmZ2dmO2aX;uJGF{e2G7 NHjFZnAyKM7:TR?= NIrRVnozPCCq NWWxPYtITE2VTx?= MWnS[ZN1d3KjdHnvckBw\iCFRmTSJIRmdHSjRkWwPEBufXSjboSgeJJi\m[rY3vpcochfG9iY3XscEB{fXKoYXPlJIF{KGeueXPv[o9zdXN? MmXKNlE6QDR7NUi=
DU145 M33yOmtqdmG|ZTDBd5NigQ>? MVOyMlUh|ryP MWKyOEBp Mk\iSG1UVw>? MYnJcohq[mm2aX;uJI9nKEiGQVOgZZN{\XO|ZXSgZZMhfXC{ZXf1cIF1cW:wIH;mJJAzOXejZkGgdJJwfGWrbjDlfJBz\XO|aX;u NUfKeJF4OjJ{NkCxOlY>
DU145 NGnXbnVMcW6jc3WgRZN{[Xl? M375b|Uh|ryP M{nrOVI1KGh? MkHrSG1UVw>? MYPJcohq[mm2aX;uJI9nKEiGQVOgZZN{\XO|ZXSgZZMhcGm|dH;u[UBJPCCjY3X0fYxifGmxbh?= MnLZNlIzPjBzNk[=
DU145 MV;LbY5ie2ViQYPzZZk> MWO1JO69VQ>? MViyOEBp MoLWSG1UVw>? NYHhdFR2UW6qaXLpeIlwdiCxZjDISGFEKGG|c3Xzd4VlKGG|IHjpd5RwdmViSEOgbJlx\XKjY3X0fYxifGmxbh?= M3TBW|IzOjZyMU[2
786-0 MVrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NX3BT5dMPi5{IN88US=> NHTlVWg4OiCq MlTySG1UVw>? MV\HTVUxRTNwMjFOwG0> MXSyNlQ{PTZ4OR?=
A498 MUXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3KzSVYvOiEQvF2= MorYO|IhcA>? NGTFc2tFVVOR NUfUNYFLT0l3ME2xMlYh|ryP NGrRUI8zOjR|NU[2PS=>
A549/ATCC MXzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mnz4Ok4zKM7:TR?= NUG4ell4PzJiaB?= NXLwTldsTE2VTx?= MoLDS2k2OD1zLk[g{txO Mnm1NlI1OzV4Nkm=
ACHN M2fNSGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIfOeoo3NjJizszN MWe3NkBp MWLEUXNQ MV\HTVUxRTFwMzFOwG0> M3P0bVIzPDN3Nk[5
BT549 MkL6S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1TDOVYvOiEQvF2= NH\NNG44OiCq NYLtdld7TE2VTx?= M1HUWWdKPTB;MT6zJO69VQ>? MWSyNlQ{PTZ4OR?=
EKVX NHvITWFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUC1Ond{Pi5{IN88US=> M3\wVFczKGh? NX\zfpFVTE2VTx?= NVvUR2dZT0l3ME2xMlMh|ryP NUOwfXhCOjJ2M{W2Olk>
HCT15 NVPZfm5xT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2XmZlYvOiEQvF2= M17YTVczKGh? MmrxSG1UVw>? M2nVb2dKPTB;Mj61JO69VQ>? MnjpNlI1OzV4Nkm=
HOP92 NUP3SJZvT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MX22MlIh|ryP M1O3XFczKGh? M{WyR2ROW09? MWLHTVUxRTRizszN NF[2bFczOjR|NU[2PS=>
IGROV1 M{LxWWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Ml7aOk4zKM7:TR?= MXi3NkBp NVvpUIxGTE2VTx?= NF36dmZIUTVyPUGuN{DPxE1? MlP0NlI1OzV4Nkm=
LOXIMVI MonFS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUDQT4FFPi5{IN88US=> MmjOO|IhcA>? NF71dm5FVVOR NF;aeYRIUTVyPUGg{txO MlSwNlI1OzV4Nkm=
M14 Mn;rS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWXjbGFbPi5{IN88US=> M1K5O|czKGh? MWHEUXNQ M1z5RmdKPTB;MT6zJO69VQ>? NGDYZVgzOjR|NU[2PS=>
MALME-3M MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFf2T3I3NjJizszN NE[2U4c4OiCq M1O1Z2ROW09? NH7O[GpIUTVyPUCuN|Ih|ryP MX[yNlQ{PTZ4OR?=
MCF10A NXm0TYpMT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3\tRVYvOiEQvF2= NFfzWYw1QCCq NYjxU2NOTE2VTx?= M4jk[mdKPTB;OT62JO69VQ>? MXeyNlQ{PTZ4OR?=
MDA-MB-435 NFfRdoJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MoXrOk4zKM7:TR?= NWqwZmM3PzJiaB?= M1m2dmROW09? Mlm2S2k2OD1yLkWg{txO M4nsU|IzPDN3Nk[5
MDA-MB-468 M3LEU2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUO2MlIh|ryP NF3WWoM4OiCq MV7EUXNQ MWnHTVUxRTBwNkOg{txO NEfU[GMzOjR|NU[2PS=>
MOLT4 M1:4UGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXWy[lVXPi5{IN88US=> MkSzO|IhcA>? NVznRnhMTE2VTx?= Mn3wS2k2OD1yLkSg{txO M2jERlIzPDN3Nk[5
NCI-ADR-RES NUC4TWtIT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWLUNYU4Pi5{IN88US=> MmewO|IhcA>? M1nuVGROW09? Mn;ZS2k2OD1yLkG2JO69VQ>? M4GzcVIzPDN3Nk[5
NCI-H23 M4LRV2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmXyOk4zKM7:TR?= MXS3NkBp NGnaSJZFVVOR NGLOSlhIUTVyPUGg{txO M3HXe|IzPDN3Nk[5
NCI-H322M MYjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlGzOk4zKM7:TR?= M2LOOVczKGh? NEP5XG1FVVOR NXS2OXppT0l3ME2wMlc6KM7:TR?= MYmyNlQ{PTZ4OR?=
NCI-H460 MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWG2MlIh|ryP NHi0TWE4OiCq NYTlSWkzTE2VTx?= M170VGdKPTB;MD63PUDPxE1? MkDHNlI1OzV4Nkm=
NCI-H522 MlrmS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGWzPZE3NjJizszN NITYSYw4OiCq M4[zZ2ROW09? MVfHTVUxRTBwNTFOwG0> NEfPSHkzOjR|NU[2PS=>
OVCAR3 NXzZOIl7T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUC2MlIh|ryP MnXqO|IhcA>? NHnlOHRFVVOR MWHHTVUxRTFwMzFOwG0> NIj1cIozOjR|NU[2PS=>
OVCAR4 NYHpPYI1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIOzWW43NjJizszN NUHnc3VtPzJiaB?= NX\RToMxTE2VTx?= M1;5cGdKPTB;NDFOwG0> M17DSVIzPDN3Nk[5
OVCAR5 NG\PWGJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXW2MlIh|ryP Mn\rO|IhcA>? M1vDZ2ROW09? Mm\XS2k2OD1yLke5JO69VQ>? MkfmNlI1OzV4Nkm=
OVCAR8 MXXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWC4dHhSPi5{IN88US=> MV[3NkBp NGjFWmZFVVOR NHzH[XVIUTVyPUCuOUDPxE1? MmTnNlI1OzV4Nkm=
RXF393 MmPMS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXHFNppqPi5{IN88US=> NHPCSFk4OiCq MX;EUXNQ MUfHTVUxRTFwMzFOwG0> MXWyNlQ{PTZ4OR?=
SF268 M3nhVWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3TVNlYvOiEQvF2= NFPJTI04OiCq M2HiXmROW09? MmDqS2k2OD1zLk[g{txO NGW2NGQzOjR|NU[2PS=>
SF295 MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M13aUVYvOiEQvF2= MYq3NkBp MorSSG1UVw>? NEixc5pIUTVyPUGuOkDPxE1? NILmXoszOjR|NU[2PS=>
SF539 M1nmdGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXPvOGJrPi5{IN88US=> MkjYO|IhcA>? MUXEUXNQ NUnvfpViT0l3ME2yJO69VQ>? MonCNlI1OzV4Nkm=
SK-MEL-2 M4\RPWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFHYXG83NjJizszN NHLzOVQ4OiCq NFzHeJlFVVOR MmS3S2k2OD1zLkOg{txO Mk\1NlI1OzV4Nkm=
SK-MEL-28 M4H2d2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NF\zdpg3NjJizszN M3nE[|czKGh? NYG1eYZSTE2VTx?= NFvFZ5pIUTVyPUGg{txO Mn3XNlI1OzV4Nkm=
SK-MEL-5 NVTTWYZJT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NH\NNoY3NjJizszN NYTLNoFiPzJiaB?= NVvpSmplTE2VTx?= NIK3ZohIUTVyPUCuOlMh|ryP NETvR4MzOjR|NU[2PS=>
SKOV3 NV7hbXlsT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmDNOk4zKM7:TR?= MWi3NkBp NWTjc3hQTE2VTx?= M1TjVGdKPTB;MTFOwG0> M4Tq[|IzPDN3Nk[5
SN12C MWfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYHLVZpvPi5{IN88US=> NUfLZXlWPzJiaB?= NIHVSIFFVVOR M{fkNGdKPTB;MjFOwG0> M{DTd|IzPDN3Nk[5
SNB19 NHj5NFNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1fUdFYvOiEQvF2= NXXU[JJHPzJiaB?= MmDwSG1UVw>? NVezUW5{T0l3ME2wMlY{KM7:TR?= M3q1XlIzPDN3Nk[5
SNB75 M1vKVGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWm2MlIh|ryP MmnEO|IhcA>? NXvxWlRxTE2VTx?= MmO2S2k2OD1yLke5JO69VQ>? M3HkO|IzPDN3Nk[5
SR Mk\nS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYK2MlIh|ryP NHnEZ4Y4OiCq MlfhSG1UVw>? MnfFS2k2OD1yLkSg{txO MkDqNlI1OzV4Nkm=
T47D MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWroSGY5Pi5{IN88US=> NIrjRXA4OiCq NUT0OZJkTE2VTx?= M3vJeWdKPTB;MD61JO69VQ>? NXzLZYVjOjJ2M{W2Olk>
TK10 MnHxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXjXT|NqPi5{IN88US=> MWe3NkBp MkLXSG1UVw>? MX\HTVUxRTBwNkOg{txO NGjo[VAzOjR|NU[2PS=>
UACC257 MYPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFrpeGc3NjJizszN MnPHO|IhcA>? NIHl[3hFVVOR MYXHTVUxRTBwNTFOwG0> NY[yOFZ4OjJ2M{W2Olk>
UACC62 MlrLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2nUeVYvOiEQvF2= M3LRWFczKGh? NGn0NG9FVVOR NUnROW9oT0l3ME2wMlQh|ryP MonQNlI1OzV4Nkm=
UO31 MnvWS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUe2MlIh|ryP M4fVVFczKGh? MmnUSG1UVw>? MkXDS2k2OD1yLkWg{txO MViyNlQ{PTZ4OR?=
Hep3B M4q4[mdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2DxWlQ5KGh? MVzEUXNQ Ml30S2k2OD1yLk[5JO69VQ>? MkO0NlI1Ozl6NkO=
BE(2)-C NWLzTFBjT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3j4W|czKGh? NX7INGl6TE2VTx?= NFXmc2tKSzdyPUKg{txO M2\Q[FIzQTN{M{G2
Bel7402 NUHBNmlYT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{HCfFczKGh? MlnYSG1UVw>? MVnHTVkxRTF5IN88US=> MW[yN|A3OTN5Nh?=
Bel7404 M3j0WGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NF20SHM4OiCq Ml;4SG1UVw>? MmXBS2k6OD1zODFOwG0> MVeyN|A3OTN5Nh?=
BGC823 MWPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4HDSlczKGh? MVLEUXNQ MkjLS2k6OD15LkWg{txO NHLzN2wzOzB4MUO3Oi=>
MGC803 NGrl[VRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWC3NkBp MVHEUXNQ MWjHTVkxRTFyLkig{txO Mn:3NlMxPjF|N{[=
SGC7901 NHiybY5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWK3NkBp NUnrcnc4TE2VTx?= M2TnWmdKQTB;OT60JO69VQ>? NUjqZYg4OjNyNkGzO|Y>
SKHEP1 MnfES5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlTxO|IhcA>? MVPEUXNQ M4XUR2dKQTB;MUeg{txO Ml[1NlMxPjF|N{[=
SMMC7721 M2WwSmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4PGeFczKGh? NXvKPVdOTE2VTx?= MlXRS2k6OD1{MDFOwG0> MoLxNlMxPjF|N{[=
NUGC3 MWDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2n2clExKM7:TR?= MorIS2k:Oi57NDFOwG0> M{jie|I{OTZ|M{Oy
A2780 CisR NW[xXGRCU2mwYYPlJGF{e2G7 M4r1TVE5KGh? Mnj2TY5pcWKrdHnvckBw\iCKRFHDJJdqfGhiSVO1NEBw\iByLkS0JO69VQ>? NVf3SnZTOjN{NUK2NFM>
CAL27 sens NYDaZ3FQU2mwYYPlJGF{e2G7 M{XRbFE5KGh? M{\PemlvcGmkaYTpc44hd2ZiSFTBR{B4cXSqIFnDOVAhd2ZiMD6zOkDPxE1? Mo\YNlMzPTJ4MEO=
CAL27 CisR MWHLbY5ie2ViQYPzZZk> M1;leFE5KGh? NXf6bpZiUW6qaXLpeIlwdiCxZjDISGFEKHerdHigTWM2OCCxZjCwMlYyKM7:TR?= NXnYdYNGOjN{NUK2NFM>
KYSE-510 CisR Mm\IT4lv[XOnIFHzd4F6 M3HMelE5KGh? MkHtTY5pcWKrdHnvckBw\iCKRFHDJJdqfGhiSVO1NEBw\iByLkW5JO69VQ>? NYH2PINsOjN{NUK2NFM>
KYSE-510 sens NInscVlMcW6jc3WgRZN{[Xl? MlmwNVghcA>? Mk\TTY5pcWKrdHnvckBw\iCKRFHDJJdqfGhiSVO1NEBw\iByLkeg{txO MVmyN|I2OjZyMx?=
MDA-MB-231 sens MmTsT4lv[XOnIFHzd4F6 MoP1NVghcA>? NF3FRXlKdmirYnn0bY9vKG:oIFjERWMhf2m2aDDJR|UxKG:oIECuOlEh|ryP NWq1bWozOjN{NUK2NFM>
MDA-MB-231 CisR MkC0T4lv[XOnIFHzd4F6 MlyzNVghcA>? MV3Jcohq[mm2aX;uJI9nKEiGQVOge4l1cCCLQ{WwJI9nKDBwNkGg{txO NUnLcY1uOjN{NUK2NFM>
ES2 NWjybYU2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MV[0PEBp NG\KNIlFVVOR Mkj6TWM2OD1zMj63JO69VQ>? M4TvcFI{PDl|NES5
MDA-MB-231 NUfyS|ZlU2mwYYPlJGF{e2G7 MV:xNEDPxE1? NH73fmw{OCCvaX6= MWDEUXNQ NXnLTYpNUW6qaXLpeIlwdiCxZjDISGFEOmF? MX:yN|Q6OzR2OR?=
MDA-MB-231 NFKzRW1McW6jc3WgRZN{[Xl? NIfBcGEyKM7:TR?= MYiyOEBp MorjSG1UVw>? NWPVT5NpUW6qaXLpeIlwdiCxZjDISGFEPiCjc4Pld5Nm\CCjczDhZ4V1gWyjdHnvckBt\X[nbIOgc4YhfHWkdXzpci=> Mor4NlM1QTN2NEm=
HS68 NXrCeYFvS3m2b4TvfIlkKEG|c3H5 NUWyb5V7OTBizszN MoDlO|IhcA>? NYnLXpltTE2VTx?= M3WxdGlEPTB;ND62JO69VQ>? MYmyN|U4ODV2Mh?=
MEF MlLRR5l1d3SxeHnjJGF{e2G7 NXP0Vm5IOTBizszN NVTObnFFPzJiaB?= NEK2T|hFVVOR NETnS|dKSzVyPUSuOEDPxE1? NUXvVoJoOjN3N{C1OFI>
BGC823 MXvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NUDV[lhHTE2VTx?= NX;ES256T0l3ME2zMlA6KM7:TR?= MV6yN|YxOTdyNh?=
High5 NGXDUYFMcW6jc3WgRZN{[Xl? MmO3NlQhcA>? NHfCbWdKdmirYnn0bY9vKG:oIHj1cYFvKHKnY3;tZolv[W62IFjERWM3KHerdHigTWM2OCCxZjCwMlA6KM7:TR?= M2\LVVI{PjB{NUKz
High5 MXvLbY5ie2ViQYPzZZk> NXfWSGZHOjRiaB?= NVTZXm11UW6qaXLpeIlwdiCxZjDoeY1idiC{ZXPvcYJqdmGwdDDISGFEOSC5aYToJGlEPTBib3[gNE4yOiEQvF2= NIHjd40zOzZyMkWyNy=>
High5 M3jOU2tqdmG|ZTDBd5NigQ>? M3LCUVI1KGh? MkHBTY5pcWKrdHnvckBw\iCqdX3hckBz\WOxbXLpcoFvfCCKRFHDN{B4cXSqIFnDOVAhd2ZiMD6xO{DPxE1? M{PnSFI{PjB{NUKz
A549 MkHOS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGLwUXVFVVOR MVzJR|UxRTFwMEe5JO69VQ>? Mli1NlM3PDR{MUC=
HCT116 NYjGT4tmT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHuxNpFFVVOR NX3iXGxZUUN3ME2wMlc2PyEQvF2= NH3IRXkzOzZ2NEKxNC=>
K562 MVXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NUD5bXRCTE2VTx?= MXLJR|UxRTBwNkS1JO69VQ>? MkPWNlM3PDR{MUC=
GBC-SD M3LNVGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWXS[GZYPSEQvF2= NV71UJVPPzJiaB?= MVfEUXNQ NWHnUVZKUUN3ME2xOE45KM7:TR?= NWCx[I5rOjN5MEeyOlA>
HGC27 NVLROI1[T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlPiOUDPxE1? M33YcVczKGh? M1X2d2ROW09? NYC2PG0xUUN3ME21MlQh|ryP MXWyN|cxPzJ4MB?=
HL60 M2nEfWtqdmG|ZTDBd5NigQ>? NE\5WZg2KM7:TR?= NX;lPWZWOjRiaB?= M2LlXmROW09? NEPiSFVKdmirYnn0bY9vKG:oIFjERWM> NFzSPWwzOzdyN{K2NC=>
Vero MVHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYe0VXN6PzJiaB?= NXPFWVdtTE2VTx?= MnvvTWM2OD1yLkmg{txO MmraNlM4QDZ2NUK=
NCI60 NYnpSo5SS3m2b4TvfIlkKEG|c3H5 MUC0PEBp Mlm0SG1UVw>? NVL0UlVYT0l;MD61N{DPxE1? NWHld2ljOjRyMUWzNlc>
SW620 M1S1XWN6fG:2b4jpZ{BCe3OjeR?= NVna[5JKPDhiaB?= MYHEUXNQ NYjpZmFvT0l;MD61OEDPxE1? NH7QR|MzPDBzNUOyOy=>
U251 NHjmXGhEgXSxdH;4bYMhSXO|YYm= NFyxOIE1QCCq NXribWxwTE2VTx?= MlfRS2k:OS53MzFOwG0> MWiyOFAyPTN{Nx?=
KM12 NGe3VXpEgXSxdH;4bYMhSXO|YYm= NXzLdGJ1PDhiaB?= MXrEUXNQ NVG1V45PT0l;MT64PEDPxE1? NHzOTpEzPDBzNUOyOy=>
Hs578T M37GcWN6fG:2b4jpZ{BCe3OjeR?= Ml;2OFghcA>? NIDQZoZFVVOR MlnIS2k:PC56MzFOwG0> NFHjdpUzPDBzNUOyOy=>
MDA-MB-231 M2faXWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MV:0PEBp NHfwWJNKSzVyPUCuNVYh|ryP M2H5e|I1ODl3MEG2
MCF7 NW\lZlR1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXG0PEBp MY\HTV0xNjR3IN88US=> NWLtNXVkOjRzMUm1OVU>
MDA-MB-435 NIX4fIhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MY[0PEBp NXfjfIhXT0l;MD64PEDPxE1? MYOyOFEyQTV3NR?=
AsPC1 M{nMXWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHHHOHI{OCEQvF2= M3XHe|Q5KGh? NF30fo5FVVOR NXHjN5JYUUN3ME2zMlY3KM7:TR?= Mn;iNlQyQDV|N{i=
Jurkat E6.1 NF76N2dMcW6jc3WgRZN{[Xl? MmrlNkBp Ml;uSG1UVw>? MVnJcohq[mm2aX;uJI9nKEiGQVO0JJdqfGhiSVO1NEBw\iByLkC0JO69VQ>? MnfkNlQzPjF6NkK=
KG1 MkLzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHK0coQ1QCCq M3\RXWlEPTB;MT6xOUDPxE1? NWLXNXRlOjR3MkWwNFM>
HEL MojWS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUi0PEBp MmjqSG1UVw>? MYXJR|UxRTBwNEmg{txO M3nlfVI1Pjl2MEW1
HSC3 MUDDfZRwfG:6aXOgRZN{[Xl? M4mxcFEzKGh? MUPEUXNQ NUK2[YR[UUN3ME2wMlcyKM7:TR?= MmXHNlQ4PjZ3NkC=
HT-29 MWDDfZRwfG:6aXOgRZN{[Xl? MormNVIhcA>? M{[wTWROW09? NG[xXolKSzVyPUCuO|Ih|ryP M2fhR|I1PzZ4NU[w
KB NGfvU2pEgXSxdH;4bYMhSXO|YYm= Mor4NVIhcA>? NFXn[JJFVVOR MljMTWM2OD1yLke1JO69VQ>? M1XmfVI1PzZ4NU[w
H460 MW\DfZRwfG:6aXOgRZN{[Xl? MWmxNkBp MU\EUXNQ NEfUSY9KSzVyPUCuPFIh|ryP MknHNlQ4PjZ3NkC=
MONE1 NY\kNYNlS3m2b4TvfIlkKEG|c3H5 NUfDNFd{OTJiaB?= NWThNWlsTE2VTx?= MmT3TWM2OD1zLkG4JO69VQ>? NIOxTIQzPDd4NkW2NC=>
MKN45 MmrER5l1d3SxeHnjJGF{e2G7 MXexNkBp NWfNcWl[TE2VTx?= MWfJR|UxRTFwMkWg{txO MU[yOFc3PjV4MB?=
TSGH NYrwZ255S3m2b4TvfIlkKEG|c3H5 NFK2U5QyOiCq NUDPbZFHTE2VTx?= NWjSfnZ7UUN3ME2yMlA6KM7:TR?= NEPGfnYzPDd4NkW2NC=>
HL60 NYfnOGVlT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4m1RlczKGh? NG\PTGdFVVOR NITMVm5IUTVyPUCuPVMh|ryP NISyTXUzPDlyMEWwNC=>
HEK293 NETs[JpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGTTO|A4OiCq NEDEWGFFVVOR MoK1S2k2OD1zMzFOwG0> MnH2NlQ6ODB3MEC=
Jurkat NEnUW|FEgXSxdH;4bYMhSXO|YYm= NF\HWocyODBizszN NHrLWWg4OiCq M1L1OWdKPTB;MD65JO69VQ>? MnzpNlQ6ODB5NEO=
GM15850 NFvneYRMcW6jc3WgRZN{[Xl? MWqyMlUh|ryP NU[zXoRWQTZiaB?= NHLxdllFVVOR NFT5T5Bld2W|IH7veEBqdmirYnn0JGhFSUNiYYPz[ZN{\WRiYYOgbY5kemWjc3WgbY4hcGm|dH;u[UBJOyCueYPpcoUhOTRiYXPleJlt[XSrb36gc4YhTliQIHflcoU> MX6xOlkzOTN4Nx?=
GM15850 M4LhcWtqdmG|ZTDBd5NigQ>? MmnmNk42KM7:TR?= M3LIPFk3KGh? MYjEUXNQ NGD1fHdld2W|IH7veEBqdmirYnn0JGhFSUNiYYPz[ZN{\WRiYYOgbY5kemWjc3WgbY4hcGm|dH;u[UBJPCCueYPpcoUhPSCjY3X0fYxifGmxbjDv[kBHYE5iZ3Xu[S=> NHvScG0yPjl{MUO2Oy=>
GM15850 NXriUlNPU2mwYYPlJGF{e2G7 NIT5dVIzNjVizszN M4TncFk3KGh? M3rOZ2ROW09? NUP5XW1x\G:nczDuc5QhcW6qaXLpeEBJTEGFIHHzd4V{e2WmIHHzJIlv[3KnYYPlJIlvKGirc4TvcoUhUDRibInzbY5mKDF{IHHj[ZR6dGG2aX;uJI9nKE[[TjDn[Y5m NX2wfVY1OTZ7MkGzOlc>
GM15850 MWPLbY5ie2ViQYPzZZk> NWPsWXdbOi53IN88US=> NYS1eFVsQTZiaB?= M4nHOmROW09? NFnX[oNld2W|IH7veEBqdmirYnn0JGhFSUNiYYPz[ZN{\WRiYYOgbY5kemWjc3WgbY4hcGm|dH;u[UBJOyCueYPpcoUhQSCjY3X0fYxifGmxbjDv[kBHYE5iZ3Xu[S=> MWexOlkzOTN4Nx?=
GM15850 NYLy[FRyU2mwYYPlJGF{e2G7 NFzYcogzNjVizszN M1f4c|k3KGh? MWDEUXNQ M3vkRYRw\XNibn;0JIlvcGmkaYSgTGRCSyCjc4Pld5Nm\CCjczDpcoNz\WG|ZTDpckBpcXO2b37lJGg1KGy7c3nu[UA5KGGlZYT5cIF1cW:wIH;mJGZZViCpZX7l MXKxOlkzOTN4Nx?=
GM15850 MVLLbY5ie2ViQYPzZZk> NVjsWpVVOi53IN88US=> NY\YVFd4QTZiaB?= NUTzbHZHTE2VTx?= MUnkc4V{KG6xdDDpcohq[mm2IFjERWMh[XO|ZYPz[YQh[XNiaX7jdoVie2ViaX6gbIl{fG:wZTDIOEBtgXOrbnWgNVYh[WOndInsZZRqd25ib3[gSnhPKGenbnW= M2TO[|E3QTJzM{[3
GM15850 M2j4ZmZ2dmO2aX;uJGF{e2G7 MkPtOUDPxE1? MWGxNkBp NFHMSldFVVOR NEXSW4Fp[XNibn:g[YZn\WO2IH;uJGZZViCvUl7BJIV5eHKnc4Ppc44> Mnj6NVY6OjF|Nke=
U937 NHfpd5pMcW6jc3WgRZN{[Xl? MnHWOUDPxE1? NFL1PVEzPCCq MknvSG1UVw>? MkXjbIF{KG6xIHXm[oVkfCCxbjDhcJBp[SC2dXL1cIlvKGGlZYT5cIF1cW:w MoiwNVc1PDd5NUC=
U937 M1:2cmtqdmG|ZTDBd5NigQ>? MX:xJO69VQ>? MoLzNlQhcA>? MYXEUXNQ NFXCZ|Jp[XNibn:g[YZn\WO2IH;uJIFteGijIIT1ZpVtcW5iYXPleJlt[XSrb36= NWrCcWNnOTd2NEe3OVA>
PANC1 MWDGeY5kfGmxbjDBd5NigQ>? MkXDNUDPxE1? MnjYNlQhcA>? NUfBPXRo\G:nczDuc5QhcW6lcnXhd4UhcW5icEK3b4lxOSCpZX7lJIV5eHKnc4Ppc44> NUOzS4RqOTd3OEi3OFQ>
PANC1 MonJSpVv[3Srb36gRZN{[Xl? MX2xJO69VQ>? MorDOFghKGh? NHnBdYtld2W|IH7veEBqdmO{ZXHz[UBqdiCyMkfrbZAyKGenbnWg[ZhxemW|c3nvci=> MmXDNVc2QDh5NES=
Caco-2 NFHlXVFHfW6ldHnvckBCe3OjeR?= M4TJWFUh|ryP NWLwZY1qOjRiaB?= NXrvVYx5TE2VTx?= MX\kc4V{KG6xdDDpcoR2[2ViUEKxW2FHOSCpZX7lJIV5eHKnc4Ppc44> NVXJPI8yOjBzNEO4OFA>
SCC4 NFLscnRHfW6ldHnvckBCe3OjeR?= M{O5bFEh|ryP M2TyZVExKG2rbh?= M{nSR2ROW09? M{PRfYhieyCwbzDh[49vcXO2IHHjeIl3cXS7IHH0JHZFWiCjc4Pld5Nm\CCjczDpcoR2[3Srb36gc4YhS1mSMkSg[4Vv\SCneIDy[ZN{cW:w NXf0Uos4OjB2NUKyNlU>
A549 NETtfJlHfW6ldHnvckBCe3OjeR?= NWTqTIlsPSEQvF2= MmrQN{Bp NVTmWnpKTE2VTx?= Mnrp[I9meyCwb4SgbY5lfWOnIHH1eI9xcGGpeTDhd5Nme3OnZDDhd{BqdmO{ZXHz[UBqdiCOQ{PJTS=> MWiyNFg2PTJyOB?=
HCT116 MoT6T4lv[XOnIFHzd4F6 M3fpPVAvOyEQvF2= NYPqcGZTOzBiaB?= NX7LdGtkTE2VTx?= MW\kc4V{KG6xdDDpcohq[mm2IFjERWMyKGG|c3Xzd4VlKGG|IHnu[JVkfGmxbjDv[kBpcXO2b37lJGg{UzliYXPleJlt[XSrb36= NXHYN3c1OjFyOEC2OFc>
HepG2 NUTlRWxuTnWwY4Tpc44hSXO|YYm= Ml\pNVAh|ryP M{nCVFI1KGh? NXy2NYo3TE2VTx?= NXjxfWRw\G:nczDuc5QhcW6mdXPlJIFxd3C2b4Ppd{Bie3Onc4Pl[EBieyCqeYDldoFk\XS7bHH0bY9vKG:oIIC1Ny=> MofDNlE2PDh3OEK=
GM11272 NXewcYh7TnWwY4Tpc44hSXO|YYm= NUPVNXlnOC5zIN88US=> NWLReVFFPzJiaB?= NYfvR2liTE2VTx?= MWXkc4V{KG6xdDDy[YFkfGm4YYTlJG1mS3B{IH31eIFvfCCneIDy[ZN{cW:w MYSyNVg1ODdzNh?=
MDA-MB-231 NGTrdFBMcW6jc3WgRZN{[Xl? MlvsNVAh|ryP NEjPbZo2KG2rbh?= NYraNJFmTE2VTx?= M3;pNYRw\XNibn;0JIlvcGmkaYSgTGRCSzKj NFvsdVkzOzR7M{S0PS=>
MDA-MB-231 NW\BfZc1U2mwYYPlJGF{e2G7 MWmxJO69VQ>? MorhNlQhcA>? M{\RdWROW09? MVfkc4V{KG6xdDDpcohq[mm2IFjERWM3KGG|c3Xzd4VlKGG|IHHj[ZR6dGG2aX;uJIxmfmWuczDv[kB1fWK3bHnu NGXjUFAzOzR7M{S0PS=>
K562 MVnLbY5ie2ViQYPzZZk> MXXkc4V{KG6xdDDpcohq[mm2IFjERWM> NI\5eGszOzV7MUGxNS=>
Jurkat MnnlR5l1d3SxeHnjJGF{e2G7 M3LMT|IxKM7:TR?= Mn6zO|IhcA>? NELQVoxFVVOR NYXhUFFKdm9iY4n0c5RwgGmlaYT5JIF{e2W|c3XkJIF{KGe{b4f0bEBqdmirYnn0bY9v M3XWT|I1OzB2M{S4
HCT116 MnG5RZBweHSxc3nzJGF{e2G7 Mo\2N{DPxE1? NHvLPHEzPCCq MoXXSG1UVw>? M3PuTYRw\XNibn;0JIlv\HWlZTDhdI9xfG:|aYOgZZN{\XO|ZXSgZZMhcW6lcnXhd4UhcW5icEWzJJBzd3SnaX6gcIV3\Wx? NF7OfZMzPDd4NkW2NC=>
KASUMI-1 NXLlUGhLT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkXiTWM2OD17OT6xO{BvVQ>? Moi2V2FPT0WU
KARPAS-45 NFjEeJpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2TGOGlEPTB;MUezMlg6KG6P NIrVWpZUSU6JRWK=
BHT-101 NHu3fo1Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHL5S2hKSzVyPUK0OE4yQCCwTR?= NFPrT4tUSU6JRWK=
H9 NGHwOXNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4\VTmlEPTB;MkW1MlA1KG6P MUTTRW5ITVJ?
PA-1 MYnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NH\1dmhKSzVyPUK4Ok4zPiCwTR?= M3i5XXNCVkeHUh?=
NEC8 NIS1O5FIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmT1TWM2OD1{OEmuN|ghdk1? M2jGWXNCVkeHUh?=
MHH-PREB-1 MYjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkK4TWM2OD1{OUSuOVMhdk1? NEHrV|NUSU6JRWK=
NB7 MUDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2\ofWlEPTB;M{S1Mlc1KG6P M{Dj[XNCVkeHUh?=
A3-KAW MX3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M33ZU2lEPTB;NECwMlU6KG6P NGruOJJUSU6JRWK=
NB69 M3nONmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIPDb3VKSzVyPUSxNU44OSCwTR?= MX\TRW5ITVJ?
EoL-1-cell MoHrS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUXRO|VWUUN3ME20OVQzPSCwTR?= NInQ[nJUSU6JRWK=
CHP-212 NGLLRWZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYPM[oNrUUN3ME20OVcvPTNibl2= M{TNenNCVkeHUh?=
C2BBe1 NIX4bGRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MoL2TWM2OD12N{KuNVkhdk1? NInVZZJUSU6JRWK=
697 M1rROmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MofFTWM2OD12N{OuOFEhdk1? M3L6e3NCVkeHUh?=
BCPAP Mn3pS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NH[1N3NKSzVyPUWwNU41OiCwTR?= NYPnTFB1W0GQR1XS
L-363 NX7UZWk4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MW\JR|UxRTVyMz6xJI5O M{fFS3NCVkeHUh?=
ES8 NFO4SHpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGHqd2ZKSzVyPUWyN{42OyCwTR?= NV3MXGx1W0GQR1XS
BE-13 M3\sZ2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{TBbWlEPTB;NUK2Mlk3KG6P M3PwSXNCVkeHUh?=
CTB-1 NVXlUI9iT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M17BbGlEPTB;NUO3MlkzKG6P MnLFV2FPT0WU
HD-MY-Z NEXmS5VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYDaT|BqUUN3ME21N|gvOTNibl2= MVPTRW5ITVJ?
NKM-1 MoS2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUX1PGd7UUN3ME21OFQvOjdibl2= Mmq2V2FPT0WU
NCI-H720 NGPLU|JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXPJR|UxRTV4MD6xPEBvVQ>? MUnTRW5ITVJ?
KY821 NFTiXoZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NF3WNIVKSzVyPUW2N{4zPSCwTR?= MlfxV2FPT0WU
OVCAR-5 MXTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVPweVRnUUN3ME21O|YvOTFibl2= NFP2RWVUSU6JRWK=
CTV-1 NVTEVnNpT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkHJTWM2OD13OEGuOVYhdk1? NF\ib3lUSU6JRWK=
P12-ICHIKAWA M3:5UWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFTKdG5KSzVyPUW5Ok42OSCwTR?= MlnBV2FPT0WU
DB MoHLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3jSSmlEPTB;NUm4MlU4KG6P MWrTRW5ITVJ?
CHL-1 MU\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{XjUWlEPTB;NkSyMlA5KG6P NETnSFZUSU6JRWK=
A4-Fuk NXftZ45mT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUfJR|UxRTZ2ND65NUBvVQ>? MmjZV2FPT0WU
MV-4-11 MXLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1u3bGlEPTB;NkW5MlEhdk1? NVq0[2JVW0GQR1XS
RPMI-8226 MmXhS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MljsTWM2OD14N{iuNVghdk1? MWTTRW5ITVJ?
NB14 NXPKUlRrT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1ntRWlEPTB;Nkm2Mlk2KG6P M1;OOnNCVkeHUh?=
DOHH-2 NXPCZ5lCT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXTJR|UxRTdyNj62PEBvVQ>? NVS0RnJwW0GQR1XS
D-423MG MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1\odmlEPTB;N{C2Mlg6KG6P MYHTRW5ITVJ?
D-283MED NVHVeWVVT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXrJR|UxRTdzND6xOEBvVQ>? MWTTRW5ITVJ?
ES1 NXy3[2Q1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEP1OWhKSzVyPUeyOE41KG6P MkDqV2FPT0WU
GOTO MlnlS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXPJR|UxRTd{OT6xNkBvVQ>? M37Gb3NCVkeHUh?=
NCI-H209 NFTadVlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MW\JR|UxRTd{OT65JI5O M2XHXHNCVkeHUh?=
MOLT-13 NUDOW5JrT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFLrR|lKSzVyPUezPE46QCCwTR?= M1fNZ3NCVkeHUh?=
ATN-1 M2rPfGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVi2e2prUUN3ME23OFAvOjhibl2= MnvLV2FPT0WU
DU-4475 NHPXZlZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWDJR|UxRTd3MT65NUBvVQ>? NIq5TYZUSU6JRWK=
NB10 MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWHJR|UxRTd3MT65NkBvVQ>? MV;TRW5ITVJ?
KG-1 M{SwNGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnrUTWM2OD15N{WuOFUhdk1? NHfNe3dUSU6JRWK=
MOLT-4 NWDE[FNkT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHnBcpVKSzVyPUe4O{41PiCwTR?= M2\U[HNCVkeHUh?=
TE-1 MUHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXrBUoZ3UUN3ME23PVEvOSCwTR?= MX;TRW5ITVJ?
SBC-1 M4rJdmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVTBR4REUUN3ME23PVMvQDRibl2= NUfJ[VByW0GQR1XS
HEL MkXRS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIfTPXpKSzVyPUiwOk4xQCCwTR?= M33OeHNCVkeHUh?=
SK-MEL-2 NULvfYw1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NInEWIhKSzVyPUiwPU41PCCwTR?= NGTFVoVUSU6JRWK=
KU812 MVvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NIfKTZBKSzVyPUixN{4yKG6P MYrTRW5ITVJ?
RPMI-8866 M4LnTGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NE[0fopKSzVyPUixN{43PyCwTR?= NXHNcHk3W0GQR1XS
ALL-PO NHy1OWZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2HNdmlEPTB;OEG0MlY3KG6P MVnTRW5ITVJ?
LU-139 NUXhdlVYT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUPwS|dWUUN3ME24NlIvQDZibl2= Ml\JV2FPT0WU
RS4-11 MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M33Yc2lEPTB;OEOyMlQ2KG6P M1HHWXNCVkeHUh?=
EW-18 NH;6[YJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUDU[Xh7UUN3ME24N|IvQTZibl2= NEm2bJhUSU6JRWK=
P30-OHK MUPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1qwRWlEPTB;OEO1Mlchdk1? MlOyV2FPT0WU
D-566MG MofVS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4r1UGlEPTB;OEO4MlYzKG6P NGfQVYJUSU6JRWK=
HSC-4 NIDY[GxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MofwTWM2OD16NE[uOVEhdk1? Moj4V2FPT0WU
QIMR-WIL NVK2Z3VRT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEX4d|VKSzVyPUi2Nk4xOyCwTR?= NUmyPGNWW0GQR1XS
SW954 M3TMcWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4XN[2lEPTB;OE[zMlE3KG6P NXrkfVBoW0GQR1XS
HGC-27 M2PsOmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3\GOWlEPTB;OEeyMlM1KG6P MkHWV2FPT0WU
HH MnXJS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4TmSGlEPTB;OEm0MlEzKG6P MnP2V2FPT0WU
KE-37 MmjiS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2nmWGlEPTB;OEm0MlYzKG6P MVrTRW5ITVJ?
SK-N-DZ MVfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NF\4dpVKSzVyPUmwNE41OyCwTR?= M4\2dHNCVkeHUh?=
J-RT3-T3-5 NVzsSWpZT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3:yNmlEPTB;OUGwMlQ6KG6P MXrTRW5ITVJ?
A427 M2fJO2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXHJR|UxRTl{MD64OEBvVQ>? MnnLV2FPT0WU
ECC10 NI[x[nJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWLJR|UxRTl2NT64O{BvVQ>? NYDnd2xtW0GQR1XS
EW-1 M4fmOmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NX;3[3F3UUN3ME25OFcvOjZibl2= NXXD[5M6W0GQR1XS
MIA-PaCa-2 NWXwZ4t5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWXDfG41UUN3ME25OFkvOTJibl2= MUDTRW5ITVJ?
HCC2218 NF72VHpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmnUTWM2OD17NUiuOFghdk1? MmH4V2FPT0WU
HAL-01 NIHKZ5hIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVHJR|UxRTl4OD6wOEBvVQ>? MXrTRW5ITVJ?
RD NV36dGNDT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NULC[YpHUUN3ME25O|QvPDVibl2= MlrzV2FPT0WU
SK-N-AS M1jLOWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3\HXWlEPTB;OUi4MlEhdk1? MVTTRW5ITVJ?
ML-2 MnrSS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUPJR|UxRTFwMEC0NFch|ryP M2WwNHNCVkeHUh?=
MEL-HO NYTTS5pwT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIXtSopKSzVyPUGuNFA2QDJizszN M{fRPXNCVkeHUh?=
MS-1 MYHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NIDMbHRKSzVyPUGuNFA3OTdizszN M1zoXnNCVkeHUh?=
NCI-SNU-1 M3vtdmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUHJR|UxRTFwMEKzN|Eh|ryP MYnTRW5ITVJ?
8505C MoLRS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXvJR|UxRTFwMEKzN|Eh|ryP NFLsOoJUSU6JRWK=
MN-60 MVvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NIDybpRKSzVyPUGuNFI3QCEQvF2= MkLZV2FPT0WU
SAS M{TsZmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYTJR|UxRTFwMESwPFEh|ryP NHS4doxUSU6JRWK=
EFM-19 NELtV21Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIG1[YpKSzVyPUGuNFQ5PzlizszN NXXvTIRvW0GQR1XS
Ca9-22 MofVS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1jCNmlEPTB;MT6wOVExPyEQvF2= MmnHV2FPT0WU
NBsusSR Mm\JS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3LwVmlEPTB;MT6wOVE3PiEQvF2= MXnTRW5ITVJ?
NB13 MXXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVLJR|UxRTFwMEW1NFEh|ryP NHfwfpJUSU6JRWK=
SF295 NXHvWVRsT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NInzXplKSzVyPUGuNFY3OjRizszN NGP1cY1USU6JRWK=
U-2-OS MYPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mn7STWM2OD1zLkC3PVEyKM7:TR?= Mn7yV2FPT0WU
NCI-H526 MorGS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVfXV2pqUUN3ME2xMlA5OjlzIN88US=> NWnkTpRsW0GQR1XS
KMOE-2 MmexS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHnKbmpKSzVyPUGuNFk1OjJizszN MoW0V2FPT0WU
RCM-1 M13zTmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MV7JR|UxRTFwMUKxNFIh|ryP M4O0eHNCVkeHUh?=
MC116 MnL1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFvDepFKSzVyPUGuNVM3OjFizszN NIPhXnhUSU6JRWK=
NCI-H1092 M1r0Z2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYrJR|UxRTFwMUW0NFYh|ryP MX;TRW5ITVJ?
EW-3 MXfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkTtTWM2OD1zLkG3NlEzKM7:TR?= MkDZV2FPT0WU
HCT-116 MV;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1LLVmlEPTB;MT6xO|c2KM7:TR?= MV7TRW5ITVJ?
MC-IXC NGjZWZRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYHyblFMUUN3ME2xMlE4QDhzIN88US=> MoXwV2FPT0WU
LB1047-RCC MVvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NF\TfFJKSzVyPUGuNVg{OTJizszN MnSyV2FPT0WU
VM-CUB-1 MmPZS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M33RW2lEPTB;MT6xPVExQCEQvF2= M1LCOXNCVkeHUh?=
NB5 NFrsU5VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVzZO2VnUUN3ME2xMlE6QDV4IN88US=> NYTidGpbW0GQR1XS
SKG-IIIa MmHsS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFPtXGVKSzVyPUGuNlM1PjRizszN NV;yUotXW0GQR1XS
HO-1-N-1 NVjaeol{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{PZR2lEPTB;MT6yN|g{PSEQvF2= NE\xcXdUSU6JRWK=
EFO-27 NEX6U5FIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NI\GcnpKSzVyPUGuNlUxPDNizszN Mom5V2FPT0WU
MHH-NB-11 M2DRcGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVvJR|UxRTFwMkizNlkh|ryP NWqzcY9TW0GQR1XS
SW620 MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mn\zTWM2OD1zLkK5NFE5KM7:TR?= M3PDV3NCVkeHUh?=
MOLT-16 MVTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVnxbG55UUN3ME2xMlI6Pzl5IN88US=> Mnu2V2FPT0WU
NTERA-S-cl-D1 NUXXWFZrT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWTBVmJmUUN3ME2xMlMyPzZzIN88US=> MULTRW5ITVJ?
VA-ES-BJ NV\3OZZ3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIjQelJKSzVyPUGuN|I1PzdizszN MoXsV2FPT0WU
HCC1419 NGfGT4xIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1S1eWlEPTB;MT6zOFAzPyEQvF2= M2TkT3NCVkeHUh?=
NCI-H69 MYXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWnJR|UxRTFwM{SxNVIh|ryP MYXTRW5ITVJ?
DEL NVvpcnV4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlHGTWM2OD1zLkO1NVYzKM7:TR?= M3nBeHNCVkeHUh?=
LXF-289 MXXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlLBTWM2OD1zLkO1NlQh|ryP NIX3bpBUSU6JRWK=
EW-11 NHL1O3lIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{jkPGlEPTB;MT6zOlAzPiEQvF2= M{jCUXNCVkeHUh?=
KP-4 MV;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4\Vd2lEPTB;MT6zO|A5PSEQvF2= NX7UVXZSW0GQR1XS
NOS-1 M2GxUWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlTOTWM2OD1zLkSxNVk1KM7:TR?= MUHTRW5ITVJ?
SK-NEP-1 NXvNOmd7T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnztTWM2OD1zLkSxOlk{KM7:TR?= NVfIeGFFW0GQR1XS
LAMA-84 MW\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{DNbmlEPTB;MT60N|k1PSEQvF2= M4fhWHNCVkeHUh?=
ES5 M1[3V2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MY\JR|UxRTFwNESzJO69VQ>? M{exc3NCVkeHUh?=
HuO9 MVvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoraTWM2OD1zLkS1N|YzKM7:TR?= MlLDV2FPT0WU
COLO-684 M3;EUGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFLCUWlKSzVyPUGuOFYyOThizszN MnfqV2FPT0WU
EW-24 M{GyWmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmPLTWM2OD1zLkS2OVMyKM7:TR?= M2DK[HNCVkeHUh?=
BV-173 NU\WcJY3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2fNbGlEPTB;MT60O|I6OSEQvF2= MV3TRW5ITVJ?
NCI-H1770 M{TZc2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3zTWmlEPTB;MT60PFU{PiEQvF2= MnnTV2FPT0WU
HuP-T4 MmXSS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHHUNJlKSzVyPUGuOFk{KM7:TR?= NXO5NGg2W0GQR1XS
TYK-nu NX35UGxtT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXS0Und{UUN3ME2xMlQ6QDVzIN88US=> MX\TRW5ITVJ?
YH-13 MljyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnPiTWM2OD1zLkS5PFk1KM7:TR?= NVy3XHdXW0GQR1XS
H4 M3jBPWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3izOGlEPTB;MT61NFkyOiEQvF2= MXHTRW5ITVJ?
OVCAR-8 NIS5[XhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MojoTWM2OD1zLkW0OFc4KM7:TR?= M{W5TnNCVkeHUh?=
NCI-H23 NYraNmlIT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkLDTWM2OD1zLkW0OlQ2KM7:TR?= Mm\VV2FPT0WU
ES7 MlXaS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mm\jTWM2OD1zLkW0O|c{KM7:TR?= Mn7QV2FPT0WU
COR-L88 MW\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYLJR|UxRTFwNU[0NlQh|ryP Mo\5V2FPT0WU
TI-73 MnPES5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NF;m[4NKSzVyPUGuOVkxPiEQvF2= MUTTRW5ITVJ?
RT-112 M1XyNGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWDJR|UxRTFwNUmyPFQh|ryP NIDDWG5USU6JRWK=
HuO-3N1 NWPWZ5k6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Moe3TWM2OD1zLkW5N|g2KM7:TR?= MU\TRW5ITVJ?
HC-1 NFvqdG5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{DYTWlEPTB;MT61PVg3PiEQvF2= NUDVR2diW0GQR1XS
HT55 M1GyUGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NELo[2tKSzVyPUGuOlUyOzFizszN MVHTRW5ITVJ?
IA-LM NI\YdW1Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWnJR|UxRTFwNkmyO|gh|ryP MoDEV2FPT0WU
EM-2 NEDh[3RIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUXJR|UxRTFwN{CwNVQh|ryP Mn;mV2FPT0WU
MHH-ES-1 NE\BPFlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MofqTWM2OD1zLkewOFM2KM7:TR?= NFm2bm1USU6JRWK=
CAL-27 M4P4d2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWPTOZI2UUN3ME2xMlcxPjJzIN88US=> M1HVc3NCVkeHUh?=
COLO-800 M1SzdGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUnJR|UxRTFwN{GxO|kh|ryP MmHzV2FPT0WU
HCE-T NHu0SIlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NV;MSGNrUUN3ME2xMlcyPSEQvF2= NX;qW2NnW0GQR1XS
CAMA-1 NHrMd4RIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NULoV5VoUUN3ME2xMlcyQTdzIN88US=> MXPTRW5ITVJ?
LOXIMVI NVnkcIRFT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NULnd|VYUUN3ME2xMlczOTFizszN MmqyV2FPT0WU
NH-12 NEPieI1Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHG3dmFKSzVyPUGuO|I3QTFizszN NWD1N3lPW0GQR1XS
TCCSUP NGXkXI5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnzKTWM2OD1zLkeyPFI6KM7:TR?= M3P3O3NCVkeHUh?=
MDA-MB-361 MljkS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MV3JR|UxRTFwN{OxOVch|ryP NYjBRpJFW0GQR1XS
EW-16 NF[3UFRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NV[2eGlvUUN3ME2xMlc1OTB5IN88US=> MVLTRW5ITVJ?
SNU-423 NIrY[5dIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4\y[WlEPTB;MT63OVgzPyEQvF2= Mm\ZV2FPT0WU
Daoy NVjZcohoT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGLRVphKSzVyPUGuO|Y{OTlizszN MkPRV2FPT0WU
ES4 MlXIS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGfDTXdKSzVyPUGuO|g4PDFizszN NFzod45USU6JRWK=
PFSK-1 NVnUblBJT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVHXWGVCUUN3ME2xMlgxOzdizszN MlHEV2FPT0WU
ES3 MmL4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXHJR|UxRTFwOEK2PFEh|ryP M1vuZ3NCVkeHUh?=
ONS-76 NWjlV|ZnT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2\FOGlEPTB;MT64Nlg6PyEQvF2= NGnnO5dUSU6JRWK=
JVM-3 M1;vV2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mlr6TWM2OD1zLki1OFUyKM7:TR?= MVzTRW5ITVJ?
OS-RC-2 MWnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{TDOmlEPTB;MT64O|E2OSEQvF2= M4nV[nNCVkeHUh?=
COLO-320-HSR MXHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3Lob2lEPTB;MT64PFE6PyEQvF2= MYHTRW5ITVJ?
HN MkHrS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYrTO4E5UUN3ME2xMlg5PzJ3IN88US=> NISxeVlUSU6JRWK=
HT NXe4dI54T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWXVN2dvUUN3ME2xMlg5QTR5IN88US=> M3PNTnNCVkeHUh?=
LoVo MnPkS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGL2XYhKSzVyPUGuPFk5OSEQvF2= NEXyS2lUSU6JRWK=
CGTH-W-1 MlL5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFvoNFVKSzVyPUGuPFk6PDZizszN MX3TRW5ITVJ?
NB6 NH7PWohIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYO4d4E1UUN3ME2xMlkyOjl6IN88US=> NV\6XY9OW0GQR1XS
EW-22 NUT2b3hUT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWrJR|UxRTFwOUK4PFch|ryP NVXj[4duW0GQR1XS
ES6 NELZN3hIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYfsPWFXUUN3ME2xMlk{PjNzIN88US=> M4PHb3NCVkeHUh?=
SCC-15 MUfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYD6OpE2UUN3ME2xMlk{QDF7IN88US=> M4XjR3NCVkeHUh?=
HL-60 MlrYS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NF7oVpRKSzVyPUGuPVM6ODJizszN MmjUV2FPT0WU
human HOP-92 MXrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXzJR|UxRTFwOUSwOlUh|ryP NUnOPFV{W0GQR1XS
SW626 NH7kcYVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MoHOTWM2OD1zLkm0PFk6KM7:TR?= NXviZY1pW0GQR1XS
HEC-1 Mmr3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NE\IR3BKSzVyPUGuPVU{PiEQvF2= MWrTRW5ITVJ?
LB2241-RCC MXvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXHlUHc3UUN3ME2xMlk5OjNzIN88US=> MUnTRW5ITVJ?
Ramos-2G6-4C10 MoHXS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYLJR|UxRTFwOUm0PVMh|ryP MlLVV2FPT0WU
A101D MmLLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHH1eJhKSzVyPUKuNlA{ODNizszN MU\TRW5ITVJ?
NCI-H446 Ml3LS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnXFTWM2OD1{LkC0OVk6KM7:TR?= MWnTRW5ITVJ?
SBC-5 NH;4ZnhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWPj[oRpUUN3ME2yMlA3OTR5IN88US=> NFXVVHBUSU6JRWK=
HOS Ml7US5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXTVUVQyUUN3ME2yMlA4PjV|IN88US=> MXLTRW5ITVJ?
K5 MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXfVO5RUUUN3ME2yMlA4QDFzIN88US=> MlXOV2FPT0WU
HLE MXvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MX;JR|UxRTJwMEi1Nlkh|ryP MY\TRW5ITVJ?
HSC-2 MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYLVcG5RUUN3ME2yMlEzQDl6IN88US=> M1jrZ3NCVkeHUh?=
LCLC-97TM1 M176cWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVnJR|UxRTJwMUS1PFMh|ryP MoXjV2FPT0WU
DMS-273 MkflS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEfzSFFKSzVyPUKuNVQ5OzdizszN M17BOHNCVkeHUh?=
TE-8 MoDBS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXvMdnR3UUN3ME2yMlE2PzZ3IN88US=> MWjTRW5ITVJ?
DSH1 MoXkS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVfJR|UxRTJwMU[zPVgh|ryP MYTTRW5ITVJ?
CAL-51 NEPXc4FIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MkPOTWM2OD1{LkG2Olk6KM7:TR?= M1jrWnNCVkeHUh?=
IST-SL1 MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUjJR|UxRTJwMU[4OFQh|ryP MlPhV2FPT0WU
GCT NHTZclFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXHScmN4UUN3ME2yMlE4PzdizszN NH24O5BUSU6JRWK=
SW948 NX;hbGI3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MX\JR|UxRTJwMUi0OVYh|ryP NGj2cVBUSU6JRWK=
NOMO-1 M1j0XGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NH\oflJKSzVyPUKuNVk{OTdizszN Mke3V2FPT0WU
C8166 NX3sfo1NT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFfIUXFKSzVyPUKuNlE{OzRizszN M2\3eHNCVkeHUh?=
OC-314 MXfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mk[xTWM2OD1{LkKzNlU6KM7:TR?= M2fSeHNCVkeHUh?=
CAL-39 MWPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2LCVWlEPTB;Mj6yN|YzPiEQvF2= MVnTRW5ITVJ?
MDA-MB-453 NYPTfJozT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4mzcGlEPTB;Mj6yOFI4PSEQvF2= MmLtV2FPT0WU
A673 MnjOS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoPITWM2OD1{LkK1PFYzKM7:TR?= MXXTRW5ITVJ?
HTC-C3 NF\RSWdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1zKfmlEPTB;Mj6yOlg2KM7:TR?= MmTuV2FPT0WU
NCI-H1666 MU\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnnRTWM2OD1{LkK4NVEyKM7:TR?= MX7TRW5ITVJ?
PSN1 MljRS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mlv0TWM2OD1{LkK4PVE{KM7:TR?= NH[5WGxUSU6JRWK=
GI-1 NHrybmdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHXSdHFKSzVyPUKuN|A2PDNizszN NWH0O|hiW0GQR1XS
HuH-7 NXzwd2NbT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHfs[XZKSzVyPUKuN|A3OzdizszN M2D1U3NCVkeHUh?=
JAR MoPOS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3HzSGlEPTB;Mj6zNVk5PyEQvF2= MmLUV2FPT0WU
5637 MU\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUDJR|UxRTJwM{KxNlkh|ryP MV3TRW5ITVJ?
GB-1 Mke2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnfQTWM2OD1{LkOyN|M2KM7:TR?= MUnTRW5ITVJ?
KP-N-YS NFTIb4pIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1XiUmlEPTB;Mj6zNlYyPSEQvF2= MYjTRW5ITVJ?
OAW-42 MUHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXfJR|UxRTJwM{O0NVYh|ryP NE\ybIpUSU6JRWK=
8-MG-BA M4DjN2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NV3acYZ6UUN3ME2yMlM{QTB4IN88US=> NUeyPIVoW0GQR1XS
RH-18 M3;kbWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NE\3W4dKSzVyPUKuN|UxOjJizszN M{XKe3NCVkeHUh?=
NCI-H1155 M1q1Nmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4XtO2lEPTB;Mj6zOlczPSEQvF2= MUfTRW5ITVJ?
NB17 M{nsUGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NUfYZXRIUUN3ME2yMlM5OjR|IN88US=> M3HFUXNCVkeHUh?=
NCI-H1437 NVTQOHNXT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NV7hRphHUUN3ME2yMlQyQDd|IN88US=> M2H4TXNCVkeHUh?=
SN12C M4XoXmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1zmbWlEPTB;Mj60N|IyPCEQvF2= M{fndHNCVkeHUh?=
HSC-3 MUHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoTWTWM2OD1{LkS0OVA6KM7:TR?= NIC2WFVUSU6JRWK=
GAMG NX34ZXVDT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2P0bmlEPTB;Mj60OFU3OSEQvF2= NVP3[Xk5W0GQR1XS
HT-1080 MonRS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1LoW2lEPTB;Mj60OFg3PCEQvF2= MYHTRW5ITVJ?
A549 MljoS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXvDbYJuUUN3ME2yMlQ1QDl|IN88US=> NH30XlVUSU6JRWK=
KNS-62 MkLYS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MV;JR|UxRTJwNEWwOlEh|ryP NGL0eoJUSU6JRWK=
YKG-1 NV;DSnE{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVzJR|UxRTJwNEW0N|ch|ryP NYHRbWFzW0GQR1XS
LU-134-A NIWyeodIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVfJR|UxRTJwNEewNFgh|ryP NYPqZ5YxW0GQR1XS
FADU MYXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFfqV4pKSzVyPUKuOFcyPjJizszN M{LsOXNCVkeHUh?=
TGBC11TKB NFSwOI5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NH\GWXdKSzVyPUKuOFcyPzdizszN MWLTRW5ITVJ?
HT-3 MlnNS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Ml2zTWM2OD1{LkS5OVM2KM7:TR?= NYDscnQ2W0GQR1XS
NCI-H2170 NFLYN|BIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVfJR|UxRTJwNUC1OFkh|ryP MXXTRW5ITVJ?
Mo-T NH3LOldIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXvG[nlpUUN3ME2yMlUxQTJ5IN88US=> MVjTRW5ITVJ?
CCRF-CEM M4jIT2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3HHemlEPTB;Mj61N|A1OyEQvF2= MWHTRW5ITVJ?
KU-19-19 NHfqbGhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnjUTWM2OD1{LkWzOVE{KM7:TR?= NFq4bmhUSU6JRWK=
NCI-H1048 Mn;DS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MkO0TWM2OD1{LkW1NFI2KM7:TR?= MVnTRW5ITVJ?
KOSC-2 MUTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnHlTWM2OD1{LkW2NFc3KM7:TR?= NWL2PIhEW0GQR1XS
A431 M4jPT2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MX3JR|UxRTJwNU[zN|Uh|ryP Ml6xV2FPT0WU
COR-L23 M3nTbGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2rhNWlEPTB;Mj61PFU3PiEQvF2= MkfJV2FPT0WU
MKN28 MVnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVH6eHZPUUN3ME2yMlU6ODN5IN88US=> MV3TRW5ITVJ?
22RV1 NWn0ZZZxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHjnR2FKSzVyPUKuOVkzPzRizszN MkjCV2FPT0WU
ABC-1 MkLnS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NInCcGlKSzVyPUKuOlA1PiEQvF2= NHnab3JUSU6JRWK=
NCI-H2126 M2XvOmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYH4Z|FVUUN3ME2yMlYxQTh2IN88US=> NEe5THJUSU6JRWK=
DoTc2-4510 MlLqS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2fqU2lEPTB;Mj62NlE5PSEQvF2= NV\oXFV7W0GQR1XS
SCC-4 MYXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoO4TWM2OD1{Lk[zNFEzKM7:TR?= NW\kVXQ{W0GQR1XS
NCI-H661 MVnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGniWmxKSzVyPUKuOlQxQDVizszN MVrTRW5ITVJ?
RPMI-2650 NYnHN3h6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3rTdmlEPTB;Mj62OFE1OyEQvF2= MnzBV2FPT0WU
NCI-H510A NVjMVWtRT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlXNTWM2OD1{Lk[0OFI3KM7:TR?= MYTTRW5ITVJ?
BPH-1 M3HB[Gdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3LWTmlEPTB;Mj62OVg2KM7:TR?= NVjOSJR7W0GQR1XS
M14 NF3jUnpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{\Y[mlEPTB;Mj62Olk6OyEQvF2= M4qzOnNCVkeHUh?=
G-402 NYrpTnpsT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkXvTWM2OD1{LkewOFUyKM7:TR?= M{PDOnNCVkeHUh?=
AsPC-1 M2rqU2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkXnTWM2OD1{LkexNVch|ryP NXjFNZVCW0GQR1XS
NB12 NIrjRVNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIDwRlRKSzVyPUKuO|E4OSEQvF2= M37B[nNCVkeHUh?=
SK-HEP-1 M37J[mdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmPCTWM2OD1{Lke0N|kyKM7:TR?= NHKy[2VUSU6JRWK=
U-266 MoPHS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVnJR|UxRTJwN{exNlEh|ryP NWfGTXA{W0GQR1XS
AM-38 NFzqXVlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1TxVmlEPTB;Mj63O|M2PSEQvF2= M{O2c3NCVkeHUh?=
PC-14 MVLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NG\4VXhKSzVyPUKuPFA2OSEQvF2= MVzTRW5ITVJ?
EGI-1 NGTqTZlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFTHdIpKSzVyPUKuPFE4PDNizszN NFTKWmRUSU6JRWK=
LS-411N MlPkS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NH\5WmxKSzVyPUKuPFI{OyEQvF2= Ml3XV2FPT0WU
BFTC-905 M1\h[Gdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmX0TWM2OD1{Lki1OVI{KM7:TR?= MWjTRW5ITVJ?
CaR-1 NULiSVk{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYDJR|UxRTJwOE[g{txO M4\tVHNCVkeHUh?=
NCI-H292 MYHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUfJR|UxRTJwOE[1PVYh|ryP NXjHR3Y6W0GQR1XS
8305C MXnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWTico9{UUN3ME2yMlg3PjR3IN88US=> NI\JdGJUSU6JRWK=
SNU-449 Mk\JS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUPJR|UxRTJwOEmxPFIh|ryP MlviV2FPT0WU
LCLC-103H NXfuR4lTT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NI[3UZJKSzVyPUKuPVA1OzhizszN MVzTRW5ITVJ?
SW1573 MYXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYPJR|UxRTJwOU[wPFIh|ryP M{LlbnNCVkeHUh?=
MLMA NInudmxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlPoTWM2OD1{Lkm2O|E4KM7:TR?= MVHTRW5ITVJ?
NCI-H1355 MWXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYLublJ[UUN3ME2zMlAxPzl4IN88US=> NUf0NZRnW0GQR1XS
RMG-I NGfi[lhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4\vSWlEPTB;Mz6wNlU6OiEQvF2= NGHQTIFUSU6JRWK=
BB65-RCC NHXI[GlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVnJR|UxRTNwMEOzNVQh|ryP Mo\0V2FPT0WU
PC-3 Mn;4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGnCZ21KSzVyPUOuNFM5PzRizszN M2nr[XNCVkeHUh?=
SF268 MVrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3XRPWlEPTB;Mz6wOFUzOyEQvF2= NGi3fYVUSU6JRWK=
NCI-H810 M{DWOmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MX3JR|UxRTNwMES4NlMh|ryP MnHtV2FPT0WU
MEG-01 MnTOS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4DNVmlEPTB;Mz6wOlE3PCEQvF2= NWrvUlIxW0GQR1XS
SW13 NYXGV25mT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mmq0TWM2OD1|LkC3PFQ4KM7:TR?= NWnMT2drW0GQR1XS
RH-1 MnXnS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M37ZbWlEPTB;Mz6xNFI4QCEQvF2= NV34[HR[W0GQR1XS
GT3TKB M4fBT2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1G5WGlEPTB;Mz6xNVI5OyEQvF2= MUjTRW5ITVJ?
TK10 MYnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXjJR|UxRTNwMUO3NlQh|ryP MX;TRW5ITVJ?
T-24 NF3aN25Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{\Q[WlEPTB;Mz6xOVA4KM7:TR?= M3LFSHNCVkeHUh?=
A498 Ml;SS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2fHbGlEPTB;Mz6yNFg4OSEQvF2= M3TxdXNCVkeHUh?=
GR-ST M1zqNmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoS1TWM2OD1|LkKyNVM6KM7:TR?= NEjnVG5USU6JRWK=
LB2518-MEL M2XSbGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWnnO3ZCUUN3ME2zMlIzOzl6IN88US=> NVPFWolwW0GQR1XS
T47D M{Xtcmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGixb2hKSzVyPUOuNlM3OjdizszN NHvkelZUSU6JRWK=
NCI-H1651 NVK3dFVTT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4PG[mlEPTB;Mz6yOFY1PCEQvF2= MmqyV2FPT0WU
EC-GI-10 NYK0OW9sT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYTJR|UxRTNwMk[xOVMh|ryP MmfIV2FPT0WU
HT-29 NHvoVnlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NITGRXFKSzVyPUOuNlY3OTRizszN M3XyOnNCVkeHUh?=
GI-ME-N MlPZS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXzJR|UxRTNwMkm1NVEh|ryP M2e2ZnNCVkeHUh?=
SW756 M17yRWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Ml[3TWM2OD1|LkK5OlI6KM7:TR?= NV;HOop{W0GQR1XS
RKO MULHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWD4XlBUUUN3ME2zMlMxPzV5IN88US=> NWTRO2dDW0GQR1XS
NCI-H1563 MkLWS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHzQdIdKSzVyPUOuN|MxOThizszN NXLad3FWW0GQR1XS
DJM-1 MkTLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVy1fVBFUUN3ME2zMlM4Pjd2IN88US=> M4LaOHNCVkeHUh?=
L-428 NFLzeFRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlzCTWM2OD1|LkSwNFQ2KM7:TR?= Mn\ZV2FPT0WU
NCI-H2122 M2eydmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEHrfm5KSzVyPUOuOFE{OTJizszN NFzHU|FUSU6JRWK=
Ca-Ski M4TDeGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUjJR|UxRTNwNEW0N{DPxE1? NUPYfoZZW0GQR1XS
639-V M1f1fGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NF3VOYFKSzVyPUOuOFYxPTdizszN NXH2fYRrW0GQR1XS
SW1116 M4T0Wmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mmm3TWM2OD1|LkS2NlY6KM7:TR?= NFzEVIdUSU6JRWK=
DMS-114 M3fsRmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWT3fIlyUUN3ME2zMlQ4ODZ4IN88US=> MXrTRW5ITVJ?
MZ2-MEL M3nMO2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWHJR|UxRTNwNEe2PFEh|ryP NHvBN4dUSU6JRWK=
COLO-829 M2TtZ2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYrJR|UxRTNwNUCwO|Mh|ryP NYnST4s2W0GQR1XS
J82 MmHxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYXvOJg{UUN3ME2zMlUxPTdizszN NFLSV45USU6JRWK=
EW-13 MkfpS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWrTWo1UUUN3ME2zMlUzPTFizszN MV\TRW5ITVJ?
RXF393 NIPscmpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MX;JR|UxRTNwNUOyPVQh|ryP MlzPV2FPT0WU
CAL-62 NVLsfm1VT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NF;MfmZKSzVyPUOuOVQ2OTRizszN NWDibZJDW0GQR1XS
OCUB-M M33uSGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MX\JR|UxRTNwNUS2OlUh|ryP M3vsNXNCVkeHUh?=
BT-474 Mn\YS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGfKRmJKSzVyPUOuOlM{OSEQvF2= NV[xbWxxW0GQR1XS
KYSE-180 Ml[xS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWnhepF4UUN3ME2zMlY{Ozd{IN88US=> NIr6cpJUSU6JRWK=
NCI-H650 NUi5RWdoT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXXWcJh{UUN3ME2zMlY1Ojh5IN88US=> MY\TRW5ITVJ?
Detroit562 M{nkNmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1mzPGlEPTB;Mz62OVAzOiEQvF2= NYTUTotiW0GQR1XS
SW48 MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NF3BUWRKSzVyPUOuOlU3PTdizszN MofmV2FPT0WU
KYSE-450 MkH0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MX;JR|UxRTNwNki1PFIh|ryP MkTDV2FPT0WU
KYSE-510 MoKyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlPiTWM2OD1|LkeyNVgyKM7:TR?= M2XB[3NCVkeHUh?=
GP5d NFrZUZFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVHtU3A5UUN3ME2zMlczQTVizszN M3PTRnNCVkeHUh?=
RPMI-7951 NHjZTXBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYfJdFVHUUN3ME2zMlc1PzJ|IN88US=> NIG2XZpUSU6JRWK=
Becker NYfwZ2ZxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Ml[zTWM2OD1|Lke1NFEzKM7:TR?= MlTrV2FPT0WU
WM-115 MVXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4TlTWlEPTB;Mz63PFE6PSEQvF2= MYnTRW5ITVJ?
G-401 NFHHVXlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXrJR|UxRTNwN{mwPFUh|ryP MV\TRW5ITVJ?
PANC-08-13 Ml7sS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MljCTWM2OD1|Lke5OlAzKM7:TR?= NULaPItLW0GQR1XS
SW982 MkfSS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MULJR|UxRTNwOEC1OVEh|ryP NX;uSoRSW0GQR1XS
D-263MG NUPJWVhIT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{\BTGlEPTB;Mz64NlA2OSEQvF2= NGfoO5NUSU6JRWK=
KM-H2 MoGyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIfTZ5BKSzVyPUOuPFI3OjRizszN NYPkT|R1W0GQR1XS
SK-MEL-3 MW\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1;rbWlEPTB;Mz64Nlg1OSEQvF2= MUjTRW5ITVJ?
NCI-H1581 NV\KZpdXT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmnkTWM2OD1|Lki0OFg5KM7:TR?= NE\GV5hUSU6JRWK=
LS-123 NEjsXXNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MkLyTWM2OD1|Lki3PVA6KM7:TR?= Mm\aV2FPT0WU
CAKI-1 M37vRWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkDqTWM2OD1|Lki5NFUzKM7:TR?= MlzUV2FPT0WU
MEL-JUSO M2H4Umdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NI\v[41KSzVyPUOuPFkyPTNizszN M2e2cHNCVkeHUh?=
HCE-4 M2myT2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkP2TWM2OD1|LkmxOlY{KM7:TR?= M4HHTnNCVkeHUh?=
TE-10 NUTwbWg6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGPNZnVKSzVyPUOuPVIxOSEQvF2= MYrTRW5ITVJ?
OVCAR-4 M4XpNmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlLNTWM2OD1|LkmyPFg6KM7:TR?= NFiyVWlUSU6JRWK=
ETK-1 Ml3tS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXPJR|UxRTNwOUS2N|Uh|ryP MnXyV2FPT0WU
A2780 MVfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4XYTWlEPTB;ND6wOVk3PiEQvF2= NXTmWnZtW0GQR1XS
LU-65 NY\yc2VTT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1X3dmlEPTB;ND6wO|Y{OyEQvF2= MX7TRW5ITVJ?
BHY MVjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3PHPWlEPTB;ND6xNlQ6PSEQvF2= M3zhSXNCVkeHUh?=
COR-L105 MVXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4nrdGlEPTB;ND6xN|A2OSEQvF2= NXfCOYlWW0GQR1XS
CAL-12T M1XrXmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NI\GS4VKSzVyPUSuNVMyODNizszN NHP4O|dUSU6JRWK=
SCH Ml:3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NX3UXJlTUUN3ME20MlE2PzR|IN88US=> M4SxUnNCVkeHUh?=
CW-2 NEfIV4JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2XzbWlEPTB;ND6xPVAxOSEQvF2= M2juN3NCVkeHUh?=
HCC1806 M4nSWWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmjSTWM2OD12LkKwN|EzKM7:TR?= Mo\YV2FPT0WU
KP-N-YN M3;2Xmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHLGRZRKSzVyPUSuNlA6OjdizszN MXHTRW5ITVJ?
T98G NFnifHJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1;oUGlEPTB;ND6yNlE2PyEQvF2= NHHieG5USU6JRWK=
CAL-54 MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVX6cGtHUUN3ME20MlIzOzhzIN88US=> M2rkOHNCVkeHUh?=
CAL-33 NVuxeoxVT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MU\JR|UxRTRwMkOwOlQh|ryP MX3TRW5ITVJ?
SNU-C2B NWTDOGR5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYLJR|UxRTRwMkS3Olkh|ryP NEDOT2NUSU6JRWK=
NUGC-3 MUPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{\HOmlEPTB;ND6yOVUxPSEQvF2= M33nW3NCVkeHUh?=
DOK NHG5Um9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWHJR|UxRTRwMk[1PVMh|ryP MmfxV2FPT0WU
MMAC-SF NUnqRXBOT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkPMTWM2OD12LkK2PFU6KM7:TR?= NUey[GhTW0GQR1XS
KYSE-70 MkfnS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnS3TWM2OD12LkK5N|Qh|ryP MmnPV2FPT0WU
A204 M2\5NGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NV3kW3JqUUN3ME20MlM2QDB|IN88US=> M3G3eXNCVkeHUh?=
SCC-25 MYHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MV\JR|UxRTRwM{W4NVkh|ryP MmjCV2FPT0WU
EPLC-272H NV3C[GduT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVTJR|UxRTRwM{i5OUDPxE1? MlXuV2FPT0WU
CAL-120 M4i5Rmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3LjOmlEPTB;ND6zPFk6OiEQvF2= NYS5V|lQW0GQR1XS
LS-513 NU\BcJJTT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIDLU3ZKSzVyPUSuOFIyQThizszN M1HYdHNCVkeHUh?=
CAPAN-1 Mk\QS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVHLNFUyUUN3ME20MlQzOzh{IN88US=> M4PXXHNCVkeHUh?=
ESS-1 M1Ts[Gdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXnPfllDUUN3ME20MlQzPzJ2IN88US=> M4jtVXNCVkeHUh?=
GMS-10 NUnrb5g1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFTLPJRKSzVyPUSuOFI5OTlizszN MWTTRW5ITVJ?
NCI-N87 MUHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1yySmlEPTB;ND61NFg3QCEQvF2= MkTLV2FPT0WU
HMV-II NYDSTW1vT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2HZfWlEPTB;ND61NVc{KM7:TR?= MkL5V2FPT0WU
COLO-741 M2fzdmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2ridWlEPTB;ND61OVk6PCEQvF2= NX7HSXFYW0GQR1XS
MKN45 MojGS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4HXeGlEPTB;ND61O|c{OiEQvF2= M2fHTHNCVkeHUh?=
OAW-28 NX:3XWRRT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mnf5TWM2OD12LkW4N|k5KM7:TR?= MmXkV2FPT0WU
OCI-AML2 NYDCNYt5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmmyTWM2OD12Lk[1NlM5KM7:TR?= MY\TRW5ITVJ?
MDA-MB-231 NVOzTlNST3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVTVSIllUUN3ME20MlcxOjR|IN88US=> M4Hl[nNCVkeHUh?=
NCI-H1648 NHXuTWZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHjBV|NKSzVyPUSuO|IzPzNizszN MYLTRW5ITVJ?
NCI-H1792 NH3UXotIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXHJR|UxRTRwN{[xNFch|ryP NIrNVXhUSU6JRWK=
GCIY M3;yOGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1Gxd2lEPTB;ND63O|QzPCEQvF2= MkOyV2FPT0WU
Hs-578-T NYjBRo1IT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1[5[GlEPTB;ND63O|Y2PSEQvF2= M2\4WnNCVkeHUh?=
SW962 MUDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXTJR|UxRTRwN{iwNVEh|ryP NGH6XIdUSU6JRWK=
NCI-H630 MmP3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmDCTWM2OD12Lke4NFgyKM7:TR?= NUHyPIY3W0GQR1XS
786-0 NIHOT5lIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXLJR|UxRTRwN{i3O|Mh|ryP M3vG[nNCVkeHUh?=
FTC-133 NFS2TXBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIXQSm9KSzVyPUSuO|kzPjNizszN NH3DWWxUSU6JRWK=
BT-20 M3qwOWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2jaXWlEPTB;ND63PVQzQSEQvF2= M2LCe3NCVkeHUh?=
Mewo MXXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWHrZZQ3UUN3ME20MlgyPzR5IN88US=> NVH6bJNHW0GQR1XS
SW780 M1zlRmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUnJR|UxRTRwOEW3OlYh|ryP NUPMXZhUW0GQR1XS
OE33 NFXoVIFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MX3JR|UxRTRwOEe3NVMh|ryP MYLTRW5ITVJ?
HCC1569 MXHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYPJR|UxRTRwOEi0OVgh|ryP NYfSbIE{W0GQR1XS
TE-6 Mmf5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Ml3BTWM2OD12LkmzPVc4KM7:TR?= NGey[4RUSU6JRWK=
SK-N-FI NUPXZWhOT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWrJR|UxRTRwOUS0NlEh|ryP MnLuV2FPT0WU
PANC-03-27 MVnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVHNT2s4UUN3ME20Mlk6QTZ{IN88US=> MnXTV2FPT0WU
MCF7 NIS3O3FIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MV\JR|UxRTVwMEC3N|gh|ryP NHfnVpdUSU6JRWK=
UACC-257 MoO3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{HWbGlEPTB;NT6wNlg1PSEQvF2= M3XxdHNCVkeHUh?=
SW1088 NHPUfphIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MkPXTWM2OD13LkCyPVQ1KM7:TR?= MkXlV2FPT0WU
A704 NGmwcmFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mn7qTWM2OD13LkCzNFYh|ryP MmjRV2FPT0WU
A2058 NFq4UZNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1Hqc2lEPTB;NT6wOVkxQCEQvF2= MVfTRW5ITVJ?
Calu-3 NWXt[WxzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmTVTWM2OD13LkC2OFUzKM7:TR?= MXLTRW5ITVJ?
RERF-LC-MS MWnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYm2cW5MUUN3ME21MlA3QTB|IN88US=> M2rwcHNCVkeHUh?=
AU565 M3jqTGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUjJR|UxRTVwMEm3NFIh|ryP NHK1c5lUSU6JRWK=
DMS-79 NVHxco1QT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWnJR|UxRTVwMUO4PFMh|ryP NIrlRlRUSU6JRWK=
DK-MG MXHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2\Ed2lEPTB;NT6xPFQ{QCEQvF2= NETadHhUSU6JRWK=
HuCCT1 NEi2PJBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MonaTWM2OD13LkKzPFU3KM7:TR?= Mo\mV2FPT0WU
HT-144 NHX1fphIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVnlU|RkUUN3ME21MlI1QTh5IN88US=> Mn:zV2FPT0WU
M059J M1PafWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXSxU3RvUUN3ME21MlI2PzZizszN M2PkdXNCVkeHUh?=
COLO-792 MUfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYnqXo9nUUN3ME21MlI3OzV4IN88US=> NFvONHhUSU6JRWK=
SF539 NXTuWmlNT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUXJR|UxRTVwMk[2N|Ih|ryP NXLOfHozW0GQR1XS
SK-UT-1 MUjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{jGTGlEPTB;NT6yO|c2OSEQvF2= MnHsV2FPT0WU
NCI-H1703 NXPyPFJGT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4fxRmlEPTB;NT6zOVgzPiEQvF2= NUHXZZp4W0GQR1XS
SW837 M2HLWGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NUPDNWFsUUN3ME21MlM4QDd6IN88US=> M3vBbnNCVkeHUh?=
U251 MmrMS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnrPTWM2OD13LkO5NFk3KM7:TR?= M1n4RXNCVkeHUh?=
SW1710 M2nGfWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlzLTWM2OD13LkSxOVU1KM7:TR?= M4C3Z3NCVkeHUh?=
NCI-H1299 MojxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXPJR|UxRTVwNE[zN|Uh|ryP M3\zb3NCVkeHUh?=
RVH-421 M33r[mdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHqxU|BKSzVyPUWuOFk6ODhizszN Ml;FV2FPT0WU
UM-UC-3 M3nmN2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{Djc2lEPTB;NT62NlY2OSEQvF2= NFq0d3JUSU6JRWK=
MDA-MB-175-VII NHnHZo9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFfFRXNKSzVyPUWuOlQxPDFizszN MWTTRW5ITVJ?
KYSE-270 Ml70S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1nsXGlEPTB;NT62OlA{OSEQvF2= MnvUV2FPT0WU
COLO-668 MnHuS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEXVSo9KSzVyPUWuO|E{OiEQvF2= MUTTRW5ITVJ?
LN-405 NXzRR5V7T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NX7le5FlUUN3ME21Mlc{ODh3IN88US=> MXPTRW5ITVJ?
HT-1376 M{PHSWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1z1XGlEPTB;NT63PFA2OiEQvF2= Ml\zV2FPT0WU
769-P MmnPS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIO3WIVKSzVyPUWuPFY4OThizszN MYPTRW5ITVJ?
HuP-T3 M2D0dWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoizTWM2OD13Lki4Olc4KM7:TR?= M4DNXnNCVkeHUh?=
MDA-MB-415 MXHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFrUVYZKSzVyPUWuPVIyOzlizszN M4PH[3NCVkeHUh?=
MKN7 NFPFV21Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWm4XYlLUUN3ME21Mlk5QCEQvF2= M2LQdXNCVkeHUh?=
KS-1 MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NUPtWWVIUUN3ME21Mlk5QDN4IN88US=> NGjIeGVUSU6JRWK=
647-V MXXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NUXhcWxnUUN3ME21Mlk6OTR6IN88US=> NXjzem5CW0GQR1XS
COLO-679 M1nqcWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoW0TWM2OD14LkCwNlU2KM7:TR?= M1;YNnNCVkeHUh?=
AN3-CA MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFTNTFRKSzVyPU[uNFM1PDFizszN Mn\FV2FPT0WU
C32 MkfCS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYC5WoJtUUN3ME22MlE{ODN2IN88US=> NV\R[GlGW0GQR1XS
KM12 M3KyNGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{GxTmlEPTB;Nj6yOFA6QSEQvF2= MnPMV2FPT0WU
KINGS-1 M2rUTWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4fuVWlEPTB;Nj6yOlE2OiEQvF2= MYjTRW5ITVJ?
KYSE-410 MmPNS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mn\DTWM2OD14LkOwOlQ2KM7:TR?= MmHQV2FPT0WU
HPAF-II M2XiT2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmLvTWM2OD14LkO1OFgh|ryP MWLTRW5ITVJ?
LAN-6 MkDJS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIrufHdKSzVyPU[uOFk3OzFizszN MV3TRW5ITVJ?
LU-99A NY\ycoRmT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnrVTWM2OD14LkW1PVg6KM7:TR?= NUHGSI9LW0GQR1XS
SJSA-1 NH63fHpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4O2SGlEPTB;Nj61OlM1PyEQvF2= MlzFV2FPT0WU
MSTO-211H M4DUS2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlTNTWM2OD14LkeyNlM{KM7:TR?= MkPPV2FPT0WU
SW900 NFPvVHVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXLJR|UxRTZwN{[yNlEh|ryP MX\TRW5ITVJ?
LNCaP-Clone-FGC NYDuc3BZT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MluxTWM2OD14LkiwOFA{KM7:TR?= M2[4OHNCVkeHUh?=
OMC-1 NUfrZ4ZbT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXeweIxQUUN3ME22Mlg2PDB{IN88US=> NF\mNGRUSU6JRWK=
IST-MEL1 MYXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVHnNnRSUUN3ME22Mlg6PjZ7IN88US=> MWDTRW5ITVJ?
TE-9 NV3ITZJPT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2\rVGlEPTB;Nj64PVg1PyEQvF2= M4n2SHNCVkeHUh?=
NCI-H2030 MojoS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmLKTWM2OD14LkmxNlI3KM7:TR?= NV\JeGYxW0GQR1XS
BFTC-909 NUfuPZNCT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M13tXGlEPTB;Nz6wNFY1OSEQvF2= M1rDZXNCVkeHUh?=
NCI-SNU-5 MkTnS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVTJR|UxRTdwMEKxOVkh|ryP MYTTRW5ITVJ?
TE-5 MmfIS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUDzUXRRUUN3ME23MlAzQDhzIN88US=> M3jjXnNCVkeHUh?=
SK-MES-1 NIrCTmtIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NELwR21KSzVyPUeuNFU1OjdizszN NH;Q[YhUSU6JRWK=
SHP-77 MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXzJR|UxRTdwMUO5OVIh|ryP M2nLUXNCVkeHUh?=
NCI-H1623 M1;2Nmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXTJR|UxRTdwMUSwO|Ih|ryP NWTENHA6W0GQR1XS
TE-11 NX;QT3hUT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{flV2lEPTB;Nz6xOVE5PCEQvF2= M1r2SXNCVkeHUh?=
EKVX NFzhPFVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWDJR|UxRTdwMUmyOlch|ryP NFXjWJdUSU6JRWK=
OVCAR-3 NUHad4o5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHzieVFKSzVyPUeuNlEyOzNizszN NVfENY43W0GQR1XS
C3A MXLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVPsUWlGUUN3ME23MlM1PTJizszN MmnnV2FPT0WU
CFPAC-1 NHnBUHhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmjDTWM2OD15LkO2NlIzKM7:TR?= MkfjV2FPT0WU
MG-63 NFfLNVRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYTNbFl[UUN3ME23MlQyQDR7IN88US=> MYDTRW5ITVJ?
KYSE-140 MWfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoPtTWM2OD15LkS0NFYyKM7:TR?= NEjPWlhUSU6JRWK=
MPP-89 MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MX;JR|UxRTdwNUm3Nlkh|ryP NVP3OVBUW0GQR1XS
COLO-824 NILWNJZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlnuTWM2OD15LkeyPFY{KM7:TR?= M3PpUnNCVkeHUh?=
SiHa M17Ye2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXTJR|UxRTdwOEO3NFch|ryP NFHzcHZUSU6JRWK=
SNU-387 NVm3WYtUT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3TORWlEPTB;Nz64OVM1PyEQvF2= NETrWWJUSU6JRWK=
A172 M{ixemdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHfPfWRKSzVyPUeuPFYyPzJizszN NFfmcplUSU6JRWK=
COLO-680N NG\J[|BIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEHNUINKSzVyPUeuPVE4OyEQvF2= MXjTRW5ITVJ?
HCC1395 MmezS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGHKV5pKSzVyPUiuNFU1PTJizszN MkXHV2FPT0WU
NCI-H28 NXLleZNJT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2fDZWlEPTB;OD6wOVk3OyEQvF2= NIqzdJVUSU6JRWK=
LC-2-ad M3G5bGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWTJR|UxRThwMkG5N|ch|ryP MkD0V2FPT0WU
S-117 MVvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYrnSJpEUUN3ME24MlI2OzV|IN88US=> M3;4NnNCVkeHUh?=
NCI-H1838 NYnWN25nT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlfYTWM2OD16LkK1O|gyKM7:TR?= MoTZV2FPT0WU
PANC-10-05 NUWxVFZwT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWjKOWxXUUN3ME24MlM4ODR5IN88US=> NFrWUZFUSU6JRWK=
KALS-1 MYTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXPJR|UxRThwNUC5Nlgh|ryP NXzvZpZkW0GQR1XS
LS-1034 NVnrXYROT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3\oWWlEPTB;OD61O|Q{PyEQvF2= MkDyV2FPT0WU
TGBC1TKB M1XseGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmPmTWM2OD16LkezOVM2KM7:TR?= Ml2zV2FPT0WU
OE19 NUTBS25oT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVvJR|UxRThwN{[yOlIh|ryP NXH0OmhnW0GQR1XS
D-502MG NXLDc49YT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoHPTWM2OD16Lke2PVk1KM7:TR?= NHXIVFlUSU6JRWK=
JEG-3 MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVX6WYRKUUN3ME24Mlc5PjF6IN88US=> M2nocHNCVkeHUh?=
DBTRG-05MG NYSxbng1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFW3NolKSzVyPUiuPFc2PjVizszN NWSxXIU1W0GQR1XS
ME-180 MVvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2XPfGlEPTB;OT6wOlczPSEQvF2= MYfTRW5ITVJ?
NCI-H1573 M{DDfmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3vhdmlEPTB;OT6xNFU{OiEQvF2= NIOySnpUSU6JRWK=
HCC2998 MVLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{nBTmlEPTB;OT6xN|Y5OSEQvF2= MXXTRW5ITVJ?
ACHN MUfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnK3TWM2OD17LkK0PVc2KM7:TR?= NHvqSoVUSU6JRWK=
D-392MG NFL6TVJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Ml7qTWM2OD17LkK1O|E2KM7:TR?= NULrenN1W0GQR1XS
no-11 M2jURWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnzlTWM2OD17LkK2NFI5KM7:TR?= Mm\RV2FPT0WU
KLE NES3XYRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVvJR|UxRTlwM{KyN|Ih|ryP Mmf6V2FPT0WU
Calu-6 M2jrfGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NInL[olKSzVyPUmuN|c2OjhizszN MUHTRW5ITVJ?
LB831-BLC NWPwWGtkT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFL0VWRKSzVyPUmuOFUyPzFizszN NF;WVnRUSU6JRWK=
SW684 MXXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkfnTWM2OD17LkS2NVE3KM7:TR?= M4TNPXNCVkeHUh?=
SH-4 NYT2V2ZDT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mon1TWM2OD17LkS5N|Y1KM7:TR?= NF3uNIpUSU6JRWK=
IST-MES1 M{TEbWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUXJR|UxRTlwNUG2OFQh|ryP M3zaPXNCVkeHUh?=
Saos-2 MkPYS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGT1b3pKSzVyPUmuOVIyQTVizszN M3i5ZXNCVkeHUh?=
NCI-H2087 M2PZfGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnnmTWM2OD17Lk[3N|UzKM7:TR?= M3fSWnNCVkeHUh?=
SCC-9 MX;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmHQTWM2OD17LkexPFE3KM7:TR?= M1HzZXNCVkeHUh?=
MFE-280 MUTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkHMTWM2OD17LkeyO|g2KM7:TR?= M3nWcHNCVkeHUh?=
BEN M4LjSGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXO4ZVF{UUN3ME25MlgzOTV7IN88US=> NX3IfGFOW0GQR1XS
CP50-MEL-B Mli0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGCyT3NKSzVyPUmuPVI1OzJizszN NGPm[49USU6JRWK=
SK-MEL-28 Mlm1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXjJR|UxRTFyLkCxPVMh|ryP NF[5ZYNUSU6JRWK=
NCI-H2452 NUGyOoJOT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVrJR|UxRTFyLkG2JO69VQ>? MlHiV2FPT0WU
NCI-H1395 M3HDbmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MofTTWM2OD1zMD6xO|gh|ryP M1q0bXNCVkeHUh?=
NCI-H2052 MlHpS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MV\JR|UxRTFyLkG4PFIh|ryP Mmq0V2FPT0WU
A375 M3\T[Wdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXzxPGFYUUN3ME2xNE4zPDV{IN88US=> Ml;kV2FPT0WU
HCC38 MkfsS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXn4[Ww3UUN3ME2xNE4{OjJizszN M{D0[nNCVkeHUh?=
LK-2 NH;rZ5pIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEm3TlFKSzVyPUGwMlQzODhizszN NHr1cZdUSU6JRWK=
SF126 NUfuRYxzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1\tS2lEPTB;MUCuOFczPyEQvF2= M{H4ZXNCVkeHUh?=
SK-MEL-1 Ml35S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVTJR|UxRTFyLke4N|gh|ryP NVSzZ|JLW0GQR1XS
ACN MVnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHP6eZhKSzVyPUGwMlg3PzlizszN MXPTRW5ITVJ?
BB30-HNC MVvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{jBfGlEPTB;MUCuPFcyOSEQvF2= M2fLcnNCVkeHUh?=
NCI-H747 NIDKenpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWXJR|UxRTFyLki3OFYh|ryP Mnz4V2FPT0WU
KYSE-150 NYDaTnRNT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYfMcHMxUUN3ME2xNU4xOzh5IN88US=> M3fiOXNCVkeHUh?=
D-247MG M2PURWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVnHO4xwUUN3ME2xNU4yODB7IN88US=> MWXTRW5ITVJ?
BxPC-3 NVj0dGh[T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{LtNWlEPTB;MUGuN|c1PyEQvF2= MUjTRW5ITVJ?
SK-MEL-30 MX;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFy0V2lKSzVyPUGxMlQxPzlizszN Ml:3V2FPT0WU
CAS-1 M4T2SWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUHJR|UxRTFzLkSxNFkh|ryP NIjDT41USU6JRWK=
no-10 NUXFSWplT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYjFTmttUUN3ME2xNk4yOjF5IN88US=> MUTTRW5ITVJ?
NCI-H2405 M3qwVWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWPzVIpxUUN3ME2xNk4zODN4IN88US=> NWX4blR4W0GQR1XS
KGN NYT5VmxHT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoTQTWM2OD1zMj6yPVAyKM7:TR?= MlS0V2FPT0WU
BB49-HNC MWHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEjsd4lKSzVyPUGyMlM6PTZizszN NWnjTnRYW0GQR1XS
NCI-H1693 NHTiO2ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEnZbYhKSzVyPUGyMlU5OTZizszN M2q1SnNCVkeHUh?=
RO82-W-1 NIrzTWdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4XMOGlEPTB;MUOuNFY1QSEQvF2= MWHTRW5ITVJ?
CAL-85-1 NYK1WXEyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4LuemlEPTB;MUOuOFM6QSEQvF2= M{jxdnNCVkeHUh?=
H-EMC-SS NH;ITHFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEfvbHVKSzVyPUGzMlkyODRizszN NVLHb3M5W0GQR1XS
SW1783 Mn;iS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGfoUolKSzVyPUG0MlI{QTFizszN M2XjeHNCVkeHUh?=
LB771-HNC NF35dWZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3PW[mlEPTB;MUSuOFE6KM7:TR?= M2Lmc3NCVkeHUh?=
HCC70 MXXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3jKTGlEPTB;MUSuOFI{OyEQvF2= NF7ZbWlUSU6JRWK=
KNS-81-FD M1PzU2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MX3JR|UxRTF2LkewOFUh|ryP MmjiV2FPT0WU
KYSE-520 MUTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoXPTWM2OD1zND65Nlch|ryP NHPDVlRUSU6JRWK=
TGBC24TKB NGqxWXNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnPyTWM2OD1zND65OVM6KM7:TR?= MUTTRW5ITVJ?
SNB75 M2HvXmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmnFTWM2OD1zNT6wO|I6KM7:TR?= NXjBW4htW0GQR1XS
SW872 MXPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnflTWM2OD1zNT6yNlE5KM7:TR?= NWjlOVdmW0GQR1XS
U031 MkC3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUnJR|UxRTF3LkiwNlgh|ryP NXy1cmRTW0GQR1XS
ChaGo-K-1 MYPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWDJR|UxRTF3LkizOVkh|ryP MXjTRW5ITVJ?
NCI-H441 MWXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkK0TWM2OD1zNj6wNFM6KM7:TR?= MYHTRW5ITVJ?
TE-12 MkfuS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoLUTWM2OD1zNj6xPFc{KM7:TR?= MkLSV2FPT0WU
NCI-H1755 M3\6OWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVLqZ5FFUUN3ME2xOk42PzNizszN MljPV2FPT0WU
KNS-42 Mn;IS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlOwTWM2OD1zNj62OVg6KM7:TR?= MUfTRW5ITVJ?
SK-PN-DW NH33RYpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mlm4TWM2OD1zNz60NlAyKM7:TR?= MkHzV2FPT0WU
NCI-H226 MmTUS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGO2SGdKSzVyPUG3Mlk{PDVizszN NHnGNVNUSU6JRWK=
K-562 M2TXbGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlfZTWM2OD1zOD62N|E4KM7:TR?= MX3TRW5ITVJ?
A388 NX7BWpJkT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkL5TWM2OD1zOT6wN|A{KM7:TR?= NFfkZ5BUSU6JRWK=
ZR-75-30 MnzoS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUDkWIl{UUN3ME2xPU4xQTZ6IN88US=> M{HWTnNCVkeHUh?=
LU-135 M3Sxdmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXuwcYluUUN3ME2xPU4zPjN4IN88US=> NUHzeI5sW0GQR1XS
NCI-H2029 MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mnr4TWM2OD1zOT62NFIyKM7:TR?= M2C0OnNCVkeHUh?=
HT-1197 MX7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NH6zVZJKSzVyPUG5MlkzOjdizszN MWHTRW5ITVJ?
IGR-1 MY\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVHJR|UxRTJyLkOxNVch|ryP MWDTRW5ITVJ?
U-87-MG NFv0VJNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVjJVGhwUUN3ME2yNE43PDF|IN88US=> MkKzV2FPT0WU
NCI-H1304 NVziO4NyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2POZWlEPTB;MkCuO|UxOSEQvF2= Moj2V2FPT0WU
RCC10RGB M{\sWmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYTJR|UxRTJzLkK4Nlkh|ryP NEX1fnFUSU6JRWK=
NCI-H520 M4LCVGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoXMTWM2OD1{Mj63OlEyKM7:TR?= MXzTRW5ITVJ?
SK-LU-1 Mm\PS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoLxTWM2OD1{Mz6wO|E5KM7:TR?= M1z6OnNCVkeHUh?=
UACC-893 NETNdXZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFvGWVZKSzVyPUKzMlExOzhizszN MnnCV2FPT0WU
NCI-H2347 M3q0N2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFHEUHZKSzVyPUKzMlI3PzRizszN NYfIR|g1W0GQR1XS
U-118-MG NF3k[2FIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2CyWGlEPTB;MkOuO|IyPyEQvF2= NVnxNoZSW0GQR1XS
NCI-H596 NYHzUJhbT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NH:w[3hKSzVyPUKzMlkxPTVizszN MV3TRW5ITVJ?
MZ1-PC M2TVcGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUDJR|UxRTJ2Lk[3OVkh|ryP MV;TRW5ITVJ?
SW1417 NXe4dGo3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MY\JR|UxRTJ3LkK0PVgh|ryP MknmV2FPT0WU
NCI-H82 M37sSmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3jBXGlEPTB;Mk[uOFI5QCEQvF2= NGG2TnRUSU6JRWK=
COLO-678 MVnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWPJR|UxRTJ5LkS5NVkh|ryP NUOw[FVFW0GQR1XS
KURAMOCHI MYTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NELnclBKSzVyPUK4MlEzPiEQvF2= MWjTRW5ITVJ?
NCI-H1650 MkPFS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnTVTWM2OD1|MD6xPVI1KM7:TR?= Mm\iV2FPT0WU
HCC1954 NWHud5JRT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{i0V2lEPTB;M{GuN|Y3PiEQvF2= NFnDRXFUSU6JRWK=
GAK M3nmRWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYK2c2dTUUN3ME2zNk4zPjF4IN88US=> M2j6c3NCVkeHUh?=
YAPC M4DJRmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFnTVlJKSzVyPUOzMlc3PDhizszN M1:zO3NCVkeHUh?=
NCI-H2228 NGjBeJZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFjZe|NKSzVyPUO0MlM3ODVizszN M4DJRXNCVkeHUh?=
VMRC-RCZ M3;vcmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlHmTWM2OD1|Nj6zNFIzKM7:TR?= M1PZfXNCVkeHUh?=
NMC-G1 NEnnO2NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVz0cHVKUUN3ME2zO{4xPTJ7IN88US=> Mlv1V2FPT0WU
D-336MG Mom1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NELJOGdKSzVyPUSxMlg1PDJizszN M2fubHNCVkeHUh?=
UACC-62 MojMS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmrlTWM2OD12Mj61OVA2KM7:TR?= M4\5enNCVkeHUh?=
C-33-A NF70WnFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1fR[WlEPTB;NEWuN|I2PiEQvF2= MlzlV2FPT0WU
HCC1937 NXPXNHROT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXjJR|UxRTR5LkG5OVgh|ryP NGj6fGJUSU6JRWK=
HDLM-2 NGGxXnZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NF7IOGJKSzVyPUS3MlIzQDdizszN Ml7oV2FPT0WU
NCI-H727 Mnr3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYL0Vm55UUN3ME20O{4zPDVzIN88US=> NVH1WW5UW0GQR1XS
NY NIP5[pJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVjJR|UxRTR7LkO5NFgh|ryP MYLTRW5ITVJ?
NCI-H2291 NFzJdW9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVjJR|UxRTR7LkizNFEh|ryP MoP6V2FPT0WU

... Click to View More Cell Line Experimental Data

In vivo Administration of Vorinostat (~100 mg/kg/day) significantly inhibits the growth of CWR22 human prostate xenografts in nude mice with tumor reductions of 78%, 97% and 97%, at doses of 25 mg/kg/day, 50 mg/kg/day and 100 mg/kg/day, respectively, compared with control. Vorinostat induces the accumulation of acetylated core histones and prostate-specific antigen mRNA expression in CWR22 cells, resulting in higher levels of serum prostate-specific antigen than predicted from tumor volume alone. [2] Oral administration of Vorinostat (0.67g/L) crosses the blood-brain barrier, increases histone acetylation in the brain, and dramatically improves the motor impairment in the R6/2 mice model of Huntington's disease. [5]

Protocol

Kinase Assay:

[1]

+ Expand

Immunoprecipitation-HDAC assays:

The lysate of Jurkat cells is incubated for 1 hour on ice and cleared by centrifugation at 12,000 g for 10 minutes at 4 °C. Supernatants are precleared with 30 μL of 50% protein G-Sepharose slurry for 1 hour at 4 °C. Beads are pelleted by centrifugation and supernatants are incubated for 1 hour at 4 °C with 10 μg of IgG fraction from anti-HDAC1 or HDAC3 polyclonal antisera (preincubated 2 hours at room temperature with either the homologous or heterologous immunizing peptide). Both antisera are raised in rabbits against the carboxylterminal peptide of HDAC1 and HDAC3 by using synthetic peptides coupled to keyhole limpet hemocyanin. 30 μL of 50% protein G-Sepharose slurry is added for 1 hour at 4 °C. Immune complexes are pelleted by centrifugation and washed three times with 1 mL of lysis buffer. Beads are resuspended in 200 μL of HDAC buffer (20 mM Tris-HCl, pH 8.0/150 mM NaCl/10% glycerol), and the HDAC assay is performed with an 3H-acetylated peptide corresponding to amino acids 1-24 of histone H4. Released [3H]acetic acid is quantified by scintillation counting. For inhibitions studies, the immunoprecipitated complexes are preincubated with the different concentrations of Vorinostat for 30 minutes at 4 °C.
Cell Research:

[2]

+ Expand
  • Cell lines: LNCaP, PC-3, and TSU-Pr1
  • Concentrations: Dissolved in DMSO, final concentrations ~7.5 μM
  • Incubation Time: 1, 2, 3 and 4 days
  • Method:

    Cells are exposed to various concentrations of Vorinostat for 1, 2, 3 and 4 days. Cell viability is assessed by trypan blue dye exclusion.


    (Only for Reference)
Animal Research:

[2]

+ Expand
  • Animal Models: Male BALB/c nude (nu/nu) mice implanted with CWR22 tumor cells
  • Formulation: Dissolved in DMSO
  • Dosages: ~100 mg/kg/day
  • Administration: Injection i.p.
    (Only for Reference)

Solubility (25°C)

In vitro DMSO 52 mg/mL (196.74 mM)
Ethanol 3 mg/mL (11.35 mM)
Water Insoluble
In vivo Add solvents individually and in order:
2% DMSO+30% PEG 300+ddH2O
5mg/mL

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 264.3
Formula

C14H20N2O3

CAS No. 149647-78-9
Storage powder
in solvent
Synonyms SAHA, MK0683, suberoylanilide hydroxamic acid

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

  • Mass
    Concentration
    Volume
    Molecular Weight

*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1
    V1
    C2
    V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT01059552 Active, not recruiting Locally Advanced Non-small Cell Lung Cancer Fox Chase Cancer Center|National Comprehensive Cancer Network December 6, 2009 Phase 1
NCT02108002 Enrolling by invitation Von Hippel-Lindau Disease National Institute of Neurological Disorders and Stroke (NINDS)|National Institutes of Health Clinical Center (CC) March 5, 2014 Phase 1
NCT03022565 Not yet recruiting Uveal Melanoma Nicolas Acquavella|University of Miami Sylvester Comprehensive Cancer Center|University of Miami April 2017 --
NCT02943642 Not yet recruiting Mycosis Fungoides Angimmune LLC|City of Hope National Medical Center|Columbia University|Dana-Farber Cancer Institute|Feinberg School of Medicine, Northwestern University|H. Lee Moffitt Cancer Center and Research Institute|Ohio State University Comprehensive Cancer Center|Rush University Medical Center|Scott and White Hospital & Clinic|Yale University|Stanford University|Thomas Jefferson University|University of Arkansas|University of Colorado Denver School of Medicine Barbara Davis Center|University of Texas Southwestern Medical Center|University of Washington|Vanderbilt University School of Medicine|Washington University School of Medicine January 2017 Phase 2
NCT02836548 Recruiting Melanoma|Skin Neoplasms The Netherlands Cancer Institute June 2016 Phase 1|Phase 2
NCT02589145 Recruiting Lymphoma M.D. Anderson Cancer Center|Celgene Corporation June 2016 Phase 1|Phase 2

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

  • * Indicates a Required Field

Frequently Asked Questions

  • Question 1:

    What’s the recommendation about reconstitution of the compound for in vivo animal study?

  • Answer:

    We recommend the following vehicle for S1047: 2% DMSO, 40% PEG 300, 5% Propylene glycol, 1% Tween 80 at 5 mg/mL.

HDAC Signaling Pathway Map

HDAC Inhibitors with Unique Features

Related HDAC Products

Tags: buy Vorinostat (SAHA, MK0683) | Vorinostat (SAHA, MK0683) supplier | purchase Vorinostat (SAHA, MK0683) | Vorinostat (SAHA, MK0683) cost | Vorinostat (SAHA, MK0683) manufacturer | order Vorinostat (SAHA, MK0683) | Vorinostat (SAHA, MK0683) distributor
×
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID