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Venlafaxine

Venlafaxine is an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI).

Catalog No.S1441

: Tel: +1-832-582-8158[email protected]

Venlafaxine Chemical Structure
Molecular Weight: 313.86

Validation & Quality Control

Quality Control & MSDS

Related Compound Libraries

Venlafaxine is available in the following compound libraries:

Inhibitor Library (96-well) FDA Approved Drug Library (96-well) Chemical Library (96-well) GPCR Small Molecule Compound Library (96-well) Pfizer Licensed Library

Product Information

Compare 5-HT Receptor Inhibitors

Dr. Antonino Maria Sparta demonstrates a breakthrough in leukemia research by utilizing two inhibitors produced by Selleck Chemicals.

Cat.No.	Product Name	Solubility (25°C)
S2232	Ketanserin (Vulketan Gel)	<1 mg/mL	2 mg/mL	<1 mg/mL
S1333	Fluoxetine HCl	4 mg/mL	69 mg/mL	69 mg/mL
S2493	Olanzapine (Zyprexa)	<1 mg/mL	63 mg/mL	9 mg/mL
S1441	Venlafaxine	55.5 mg/mL	55.5 mg/mL	55.5 mg/mL
S1615	Risperidone (Risperdal)	<1 mg/mL	3 mg/mL	4 mg/mL
S2459	Clozapine (Clozaril)	<1 mg/mL	65 mg/mL	32 mg/mL
S1283	Asenapine	<1 mg/mL	80 mg/mL	<1 mg/mL
S1336	Fluvoxamine maleate	<1 mg/mL	87 mg/mL	87 mg/mL
S2698	RS-127445	<1 mg/mL	56 mg/mL	8 mg/mL
S3005	Paroxetine HCl	10 mg/mL	73 mg/mL	35 mg/mL
S1432	Sumatriptan succinate	83 mg/mL	83 mg/mL	<1 mg/mL
S1488	Naratriptan HCl	22 mg/mL	74 mg/mL	<1 mg/mL
S1649	Zolmitriptan (Zomig)	<1 mg/mL	58 mg/mL	58 mg/mL
S2541	Clomipramine HCl (Anafranil)	70 mg/mL	70 mg/mL	70 mg/mL
S2691	BMY 7378	92 mg/mL	92 mg/mL	20 mg/mL
S2663	WAY-100635 HCl	<1 mg/mL	85 mg/mL	85 mg/mL
S2677	BRL-15572	<1 mg/mL	96 mg/mL	40 mg/mL
S1975	Aripiprazole (Abilify)	<1 mg/mL	90 mg/mL	<1 mg/mL
S2849	SB-269970 HCl	<1 mg/mL	11 mg/mL	<1 mg/mL
S2875	Prucalopride	<1 mg/mL	60 mg/mL	38 mg/mL
S2894	SB-742457	<1 mg/mL	78 mg/mL	2 mg/mL
S1243	Agomelatine	<1 mg/mL	49 mg/mL	49 mg/mL
S1245	Dimebon (Latrepirdine)	79 mg/mL	24 mg/mL	13 mg/mL
S1345	Granisetron HCl	70 mg/mL	1 mg/mL	1 mg/mL
S1385	Mosapride citrate	<1 mg/mL	90 mg/mL	<1 mg/mL
S1390	Ondansetron HCl (Zofran)	24 mg/mL	66 mg/mL	10 mg/mL
S1436	Tianeptine sodium	92 mg/mL	92 mg/mL	92 mg/mL
S1607	Rizatriptan Benzoate (Maxalt)	46 mg/mL	20 mg/mL	<1 mg/mL
S1869	Dapoxetine HCl (Priligy)	68 mg/mL	68 mg/mL	68 mg/mL
S1898	Tropisetron	64 mg/mL	35 mg/mL	<1 mg/mL
S2669	LY310762	<1 mg/mL	0.4 mg/mL	<1 mg/mL
S1996	Ondansetron (Zofran)	<1 mg/mL	0.1 mg/mL	<1 mg/mL
S2582	Trazodone HCl (Desyrel)	<1 mg/mL	1 mg/mL	<1 mg/mL
S2025	Urapidil HCl	85 mg/mL	24 mg/mL	1 mg/mL
S2084	Duloxetine HCl (Cymbalta)	<1 mg/mL	67 mg/mL	<1 mg/mL
S2106	Azasetron HCl (Y-25130)	3 mg/mL	<1 mg/mL	<1 mg/mL
S2096	Almotriptan malate (Axert)	<1 mg/mL	94 mg/mL	53 mg/mL
S2112	Blonanserin (Lonasen)	<1 mg/mL	<1 mg/mL	<1 mg/mL
S3175	Atomoxetine HCl	2 mg/mL	58 mg/mL	37 mg/mL
S3183	Amitriptyline HCl	15 mg/mL	63 mg/mL	63 mg/mL
S2860	IEM 1754 Dihydrobromide	82 mg/mL	82 mg/mL	<1 mg/mL
S2852	BRL 54443	<1 mg/mL	46 mg/mL	2 mg/mL
S3050	Palonosetron HCl	67 mg/mL	<1 mg/mL	<1 mg/mL
S2865	VUF 10166	<1 mg/mL	21 mg/mL	61 mg/mL
S2856	SB 271046	<1 mg/mL	40 mg/mL	<1 mg/mL
S8010	PRX-08066	104 mg/mL	104 mg/mL	98 mg/mL
S8021	Vortioxetine (Lu AA21004) hydrobromide	<1 mg/mL	76 mg/mL	17 mg/mL
S4053	Sertraline HCl	<1 mg/mL	69 mg/mL	15 mg/mL

Product Description

Biological Activity Chemical Information Tech Support & FAQs

Biological Activity

Venlafaxine is an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI). It is surprisingly effective in treating depression in heroin and other opioid addicts compared to all other conventional antidepressants. In children and adolescents, venlafaxine (like other antidepressants) has a potential to increase suicidal thoughts, attempts and events of self-harm. ^[1]

Chemical Information

Download Venlafaxine SDF

Molecular Weight (MW)	313.86
Formula	C₁₇H₂₇NO₂·HCl
CAS No.	99300-78-4, 93413-69-5 (free base)
Synonyms	Effexor, Efexor

Solubility (25°C) DMSO 55.5 mg/mL Water 55.5 mg/mL Ethanol 55.5 mg/mL
Storage	2 years -20°CPowder
	2 weeks4°Cin DMSO
	6 months-80°Cin DMSO

Chemical Name	1-(2-(dimethylamino)-1-(4-methoxyphenyl)ethyl)cyclohexanol hydrochloride

Molarity Calculator Dilution Calculator Molecular Weight Calculator

Research Area

Tech Support & FAQs

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3Monday–Friday 9:00 AM–5:00 PM (Central Time)

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Related 5-HT Receptor Antagonists & Agonists

WAY-100635 HCl
WAY 100635 is a potent and selective 5-HT agonist with IC50 of 0.95 nM.
LY310762
LY310762 is a 5-HT_1D antagonist with K_i of ~0.2 μM.
BRL-15572
BRL-15572 is a 5-HT_1D antagonist with pK_i of 7.9.
BMY 7378
BMY 7378 is a multiple inhibitors of α_2C-adrenoceptor and α_1D-adrenoceptor with pK_i of 6.54 and 8.2, respectively.
RS-127445
RS-127445 is a selective 5-HT2B antagonist with pK_i of 9.5 and pIC50 of 10.4.
SB-269970 HCl
SB-269970 HCl is a hydrochloride salt form of SB-269970, which is a 5-HT₇ receptor antagonist with pK_i of 8.3.
BRL 54443
BRL 54443 is a 5-HT_1E and 5-HT_1F receptor agonist with pK_i of 8.7 and 9.25, respectively.
SB 271046
SB-271046 is a potent, selective and orally active 5-HT6 receptor antagonist with pK_i of 8.9.
IEM 1754 Dihydrobromide
IEM 1754 dihydrobroMide is a selective AMPA/kainate receptor blockers for GluR1 and GluR3 with IC50 of 6 μM.
VUF 10166
VUF10166 is a novel, potent and competitive antagonist to 5-HT₃A with K_i of 0.04 nM.

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