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Minoxidil

Synonyms: U-10858

Minoxidil (U-10858) is a vasodilator medication known for its ability to slow or stop hair loss and promote hair regrowth. Minoxidil is an ATP-sensitive potassium (KATP) channel opener, a potent oral antihypertensive agent and a peripheral vasodilator that promotes vasodilation also affects hair growth.

Minoxidil Chemical Structure

Minoxidil Chemical Structure

CAS: 38304-91-5

Selleck's Minoxidil has been cited by 1 Publication

1 Customer Review

Purity & Quality Control

Batch: Purity: 99.99%
99.99

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Biological Activity

Description Minoxidil (U-10858) is a vasodilator medication known for its ability to slow or stop hair loss and promote hair regrowth. Minoxidil is an ATP-sensitive potassium (KATP) channel opener, a potent oral antihypertensive agent and a peripheral vasodilator that promotes vasodilation also affects hair growth.
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT02198261 Completed
Androgenetic Alopecia
Applied Biology Inc.
 July 2014 --
NCT02206802 Completed
Alopecia|Female Pattern Hair Loss
Applied Biology Inc.
 July 2014 --
NCT01650272 Unknown status
Objective (Goal)|Self-Assessment|Adverse Effects
Siriraj Hospital
 June 2012 Phase 1|Phase 2
NCT01309191 Completed
Androgenetic Alopecia
University Hospitals Cleveland Medical Center|University of California San Francisco|Kaiser Permanente
 April 2011 Not Applicable

Chemical Information & Solubility

Molecular Weight 209.25 Formula

C9H15N5O
CAS No. 38304-91-5 SDF Download Minoxidil SDF
Smiles C1CCN(CC1)C2=NC(=N)N(C(=C2)N)O
Storage (From the date of receipt)

In vitro
Batch:

Ethanol : 7 mg/mL

DMSO : 2 mg/mL ( (9.55 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : Insoluble


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

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Mass Concentration Volume Molecular Weight

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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