Research Area
Product Type
United States ( Change Country )
Ki16425 Chemical Structure
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Biological Activity
Lysophosphatidic acid (LPA) exerts a variety of biological responses through specific receptors: three subtypes of the EDG-family receptors, LPA1, LPA2, and LPA3 (formerly known as EDG-2, EDG-4, and EDG-7, respectively). [1]
Ki16425 is a LPA receptor inhibitor with selectivity for LPA1 (Ki = 0.34µM)and LPA3(Ki = 0.93µM)vs. LPA2(Ki = 6.5µM). [1]Ki16425 also inhibited LPA-induced longterm responses, including DNA synthesis and cell migration. [1]
Chemical Information
| Molecular Weight (WM): | 474.96 |
|---|---|
| Formula: | C23H23ClN2O5S |
| CAS No.: | 355025-24-0 |
| Synonyms: |
Ki-16425
|
| Dissolve in (25°C): | DMSO ≥95mg/mL |
| Water <1mg/mL | |
| Ethanol ≥95mg/mL | |
| Storage: | 2 years-20°CPowder |
| 1 week-4°Cin DMSO | |
| 1 month-80°in DMSO |
Quality Control & MSDS
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