Home Metabolism Dehydrogenase inhibitor Enoxolone For research use only.

Enoxolone

Synonyms: Glycyrrhetin

Enoxolone (Glycyrrhetin) is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid, which was obtained from the herb liquorice.

Enoxolone Chemical Structure

Enoxolone Chemical Structure

CAS: 471-53-4

Selleck's Enoxolone has been cited by 1 publication

Purity & Quality Control

Batch: Purity: 99.99%
99.99

Enoxolone Related Products

Signaling Pathway

Dehydrogenase Signaling Pathways

Dehydrogenase Signaling Pathway

Choose Selective Dehydrogenase Inhibitors

Biological Activity

Description Enoxolone (Glycyrrhetin) is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid, which was obtained from the herb liquorice.
Targets
15-hydroxyprostaglandin dehydrogenase [1]
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT02939144 Completed
Apparent Mineralocorticoid Excess
The Royal Wolverhampton Hospitals NHS Trust
 November 2016 Not Applicable

Chemical Information & Solubility

Molecular Weight 470.68 Formula

C30H46O4
CAS No. 471-53-4 SDF Download Enoxolone SDF
Smiles CC1(C2CCC3(C(C2(CCC1O)C)C(=O)C=C4C3(CCC5(C4CC(CC5)(C)C(=O)O)C)C)C)C
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 94 mg/mL ( (199.71 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : Insoluble

Ethanol : Insoluble


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In vivo
Batch:

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In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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