Research Area
Product Type
United States ( Change Country )
Enoxolone (Glycyrrhetin) Chemical Structure
Recommended Products
(-)-Epigallocatechin gallate
(-)-Epigallocatechin gallate is a potent anti-oxidant polyphenol flavonoid isolated from green tea.
(+)-Usniacin (D-Usnic acid)
(+)-Usniacin(D-Usnic acid) is a naturally occurring dibenzofuran derivative found in several lichen species.
3-Indolebutyric acid (IBA)
3-Indolebutyric acid(IBA) is a plant hormone in the auxin family and is an ingredient in many commercial plant rooting horticultural products.
4-Methylumbelliferone(4-MU)
4-Methylumbelliferone is a hyaluronic acid (HA) synthesis inhibitor with an IC50 of 0.4 mM.
Aesculin (Esculin)
Aesculin(Esculin) is a glucoside found in horse chestnuts.
Aloe-emodin
Aloe-emodin is an interferon-inducing agent with IC50 of about 1 μg/mL for JEV and of about 0.33 μg/mL for EV71.
Amygdalin
Amygdalin is a glycoside initially isolated from the seeds of the tree Prunus dulcis, also known as bitter almonds.
Andrographolide
Andrographolide is a labdane diterpenoid that is the main bioactive component of the medicinal plant Andrographis paniculata.
Arbutin (Uva, p-Arbutin)
Arbutin(Uvasol, p-Arbutin) is a tyrosinase inhibitor with an IC50 of 1.09 mM.
Artesunate
Artesunate is a part of the artemisinin group of agents with an IC50 of < 5 μM for small cell lung carcinoma cell line H69.
Biological Activity
Enoxolone is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid, which was obtained from the herb liquorice.It inhibits the enzymes (15-hydroxyprostaglandin dehydrogenase and delta-13-prostaglandin) that metabolize the prostaglandins PGE-2 and PGF-2α to their respective 15-keto-13,14-dihydro metabolites which are inactive. This causes an increased level of prostaglandins in the digestive system. Prostaglandins inhibit gastric secretion but stimulate pancreatic secretion and mucous secretion in the intestines and markedly increase intestinal motility. [1]
Chemical Information
| Molecular Weight (WM): | 470.68 |
|---|---|
| Formula: | C30H46O4 |
| CAS No.: | 471-53-4 |
| Synonyms: |
Glycyrrhetin, Uralenic acid
|
| Dissolve in (25°C): | DMSO ≥94mg/mL |
| Water <1mg/mL | |
| Ethanol ≥94mg/mL | |
| Storage: | 2 years-20°CPowder |
| 1 week-4°Cin DMSO | |
| 1 month-80°in DMSO |
Quality Control & MSDS
Research Area
Related Inhibitors
Recommended Screening Libraries
Chemical Library
A collection of 864 bioactive compounds
Inhibitor Library
A collection of 481 inhibitors
Kinase Inhibitor Library
A collection of 194 kinase inhibitors
Tyrosine Kinase Inhibitor Library
A collection of 85 tyrosine kinase inhibitors.
FDA Approved Drug Library
A collection of 426 FDA approved drugs
Natural Product Library
A collection of 139 natural products
Chemotherapeutic Agent Library
A collection of 40 chemotherapeutic agents
Epigenetics Compound library
A unique collection of 17 small molecule modulators
Stem Cell Compound library
A unique collection of 47 small molecule inhibitors
GPCR Compound library
A unique collection of 63 GPCR small molecules
Keywords:buy Enoxolone (Glycyrrhetin) | Enoxolone (Glycyrrhetin) supplier | purchase Enoxolone (Glycyrrhetin) | Enoxolone (Glycyrrhetin) cost | Enoxolone (Glycyrrhetin) manufacturer | order Enoxolone (Glycyrrhetin) | Enoxolone (Glycyrrhetin) distributor