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S3051
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Bosentan Hydrate |
Bosentan is an endothelin (ET) receptors antagonist for ET-A and ET-B with Ki of 4.7 nM and 95 nM, respectively. |
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S1456
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Zibotentan (ZD4054) |
Zibotentan (ZD4054) is a specific Endothelin A (ETA) antagonist with IC50 of 21 nM. |
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S3034
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Sitaxentan sodium (TBC-11251) |
Sitaxentan sodium (TBC-11251) is a selective endothelin receptor-A antagonist with IC50 and Ki of 1.4 nM and 0.43 nM, respectively. |
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S8051
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Macitentan |
Macitentana (Actelion-1, ACT-064992) is an orally active, non-peptide dual endothelin (ET)A/B receptor antagonist with IC50 of 0.5 nM/391 nM.
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