SGLT2 Selective Inhibitors
|Catalog No.||Product Name||Information||Selective / Pan||IC50 / Ki|
Dapagliflozin is a potent and selective hSGLT2 inhibitor with EC50 of 1.1 nM, exhibiting 1200-fold selectivity over hSGLT1. Phase 4.
|Selective||hSGLT2, EC50: 1.1 nM|
Canagliflozin is a highly potent and selective SGLT2 inhibitor for hSGLT2 with IC50 of 2.2 nM, exhibits 413-fold selectivity over hSGLT1.
|Selective||mSGLT2, IC50: 2 nM; rSGLT2, IC50: 3.7 nM; hSGLT2, IC50: 4.4 nM|
|S8022||Empagliflozin (BI 10773)||
Empagliflozin (BI-10773) is a potent and selective SGLT-2 inhibitor with IC50 of 3.1 nM, exhibits >300-fold selectivity over SGLT-1, 4, 5 and 6. Phase 3.
|Selective||SGLT2, IC50: 3.1 nM|
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