Zoxazolamine

Catalog No.S4233 Synonyms: NSC 24995, Contrazole

Zoxazolamine Chemical Structure

Molecular Weight(MW): 168.58

Zoxazolamine is a centrally acting myorelaxant, which is formerly used as an antispasmodic and uricosuric.

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Biological Activity

Description Zoxazolamine is a centrally acting myorelaxant, which is formerly used as an antispasmodic and uricosuric.
In vitro

Zoxazolamine is in the centrally-acting muscle relaxant class of drugs, which reportedly act by decreasing CNS interneuronal activity. These drugs, but not anxiolytics, decrease dopaminergic turnover and induce a pacemaker-like discharge pattern in dopaminergic neurons.[1] Zoxazolamine is a member of the large class of biologically active 2-amino-2-oxazoles. Zoxazolamine is also used as a tool for assessing hepatic cytochrome P-450 activity.[2]

Protocol

Solubility (25°C)

In vitro DMSO 34 mg/mL (201.68 mM)
Ethanol 34 mg/mL (201.68 mM)
Water Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 168.58
Formula

C7H5ClN2O

CAS No. 61-80-3
Storage powder
in solvent
Synonyms NSC 24995, Contrazole

Bio Calculators

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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