Veratraldehyde (3,4-Dimethoxybenzaldehyde)

Catalog No.S3214 Synonyms: VD, VAD, VAld, Verapamil Related Compound E, Methylvanillin, NSC 24521, NSC 8500, Vanillin methyl ether, 4-O-methylvanillin, veratric aldehyde

For research use only.

Veratraldehyde (3,4-dimethoxybenzaldehyde, VD, VAD, VAld, Verapamil Related Compound E, Methylvanillin), a derivative of vanillin, is the chemical that is found and isolated from peppermint, ginger, bourbon vanilla, and fruits such as raspberry. Veratraldehyde is widely used as a flavorant and odorant because of its pleasant woody fragrance. Veratraldehyde also acts as a redox cycle agent.

Veratraldehyde (3,4-Dimethoxybenzaldehyde) Chemical Structure

CAS No. 120-14-9

Purity & Quality Control

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Biological Activity

Description Veratraldehyde (3,4-dimethoxybenzaldehyde, VD, VAD, VAld, Verapamil Related Compound E, Methylvanillin), a derivative of vanillin, is the chemical that is found and isolated from peppermint, ginger, bourbon vanilla, and fruits such as raspberry. Veratraldehyde is widely used as a flavorant and odorant because of its pleasant woody fragrance. Veratraldehyde also acts as a redox cycle agent.

Protocol (from reference)

Solubility (25°C)

In vitro

DMSO 33 mg/mL
(198.59 mM)
Ethanol 33 mg/mL
(198.59 mM)
Water Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 166.17
Formula

C9H10O3

CAS No. 120-14-9
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles COC1=C(C=C(C=C1)C=O)OC

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Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04977310 Not yet recruiting Device: CardioMEMS Heart Failure STAVROS G DRAKOS|Abbott|University of Utah December 1 2021 Not Applicable
NCT04672707 Not yet recruiting Drug: Bromhexine Hydrochloride Tablet Pharmacokinetics Second Affiliated Hospital of Wenzhou Medical University|Wanbangde Pharmaceutical Group Co. LTD December 12 2021 Phase 1
NCT04580407 Not yet recruiting Biological: TAK-672 Acquired Hemophilia A Takeda November 1 2021 Phase 2|Phase 3
NCT05004987 Not yet recruiting Drug: Escitalopram Oxalate|Drug: Placebo Alzheimer Disease|Major Depressive Disorder NYU Langone Health|National Institute on Aging (NIA) October 1 2021 Phase 4
NCT05023525 Not yet recruiting Drug: HSK31858 tablet|Drug: Placebo tablet Healthy Haisco Pharmaceutical Group Co. Ltd.|Haisco Pharmaceutical(Australia) Pty Ltd. October 2021 Phase 1

(data from https://clinicaltrials.gov, updated on 2021-09-06)

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