Venlafaxine

Catalog No.S5655 Synonyms: Wy 45030

For research use only.

Venlafaxine (Wy 45030) is an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI), used to treat major depressive disorder (MDD), generalised anxiety disorder (GAD), panic disorder and social phobia.

Venlafaxine Chemical Structure

CAS No. 93413-69-5

Purity & Quality Control

Choose Selective Serotonin Transporter Inhibitors

Biological Activity

Description Venlafaxine (Wy 45030) is an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI), used to treat major depressive disorder (MDD), generalised anxiety disorder (GAD), panic disorder and social phobia.
Targets
serotonin-norepinephrine reuptake [1]

Protocol (from reference)

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight 277.40
Formula

C17H27NO2

CAS No. 93413-69-5
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles CN(C)CC(C1=CC=C(C=C1)OC)C2(CCCCC2)O

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Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04708834 Enrolling by invitation Drug: Troriluzole (BHV-4157) Obsessive Compulsive Disorder Biohaven Pharmaceuticals Inc. March 30 2021 Phase 3
NCT03532477 Recruiting Drug: Venlafaxine Obesity Morbid Norwegian University of Science and Technology|St. Olavs Hospital|Volvat Medisinsk Senter Stokkan|Namsos Hospital|Alesund Hospital November 2 2016 --
NCT02637193 Completed Drug: Venlafaxine|Drug: Moxifloxacin|Drug: Drug - placebo Healthy Subjects Pfizer''s Upjohn has merged with Mylan to form Viatris Inc.|Pfizer December 2015 Phase 1
NCT02005107 Completed Drug: Venlafaxine IR and Venlafaxine XR Roux en Y Gastric Bypass|Sleeve Gastrectomy North Dakota State University|Neuropsychiatric Research Institute Fargo North Dakota December 2013 Phase 4
NCT01867255 Completed Drug: venlafaxine ER (extended-release) 75 mg Bariatric Surgery|Gastric Bypass|Roux-en-Y Gastric Bypass Mayo Clinic October 2013 Phase 1

(data from https://clinicaltrials.gov, updated on 2022-08-01)

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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