Venlafaxine

For research use only.

Catalog No.S5655 Synonyms: Wy 45030

Venlafaxine Chemical Structure

CAS No. 93413-69-5

Venlafaxine (Wy 45030) is an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI), used to treat major depressive disorder (MDD), generalised anxiety disorder (GAD), panic disorder and social phobia.

Purity & Quality Control

Choose Selective Serotonin Transporter Inhibitors

Biological Activity

Description Venlafaxine (Wy 45030) is an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI), used to treat major depressive disorder (MDD), generalised anxiety disorder (GAD), panic disorder and social phobia.
Targets
serotonin-norepinephrine reuptake [1]
()

Protocol

References

Solubility (25°C)

In vitro DMSO 55 mg/mL (198.26 mM)
Water Insoluble
Ethanol Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 277.40
Formula

C17H27NO2

CAS No. 93413-69-5
Storage powder
in solvent
Synonyms Wy 45030
Smiles CN(C)CC(C1=CC=C(C=C1)OC)C2(CCCCC2)O

In vivo Formulation Calculator (Clear solution)

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Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and SDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

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* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / COA (available online).

The Serial Dilution Calculator Equation

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Molecular Weight Calculator

Molecular Weight Calculator

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Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

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Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04708834 Enrolling by invitation Drug: Troriluzole (BHV-4157) Obsessive Compulsive Disorder Biohaven Pharmaceuticals Inc. March 30 2021 Phase 3
NCT03532477 Recruiting Drug: Venlafaxine Obesity Morbid Norwegian University of Science and Technology|St. Olavs Hospital|Volvat Medisinsk Senter Stokkan|Namsos Hospital|Alesund Hospital November 2 2016 --
NCT02637193 Completed Drug: Venlafaxine|Drug: Moxifloxacin|Drug: Drug - placebo Healthy Subjects Pfizer''s Upjohn has merged with Mylan to form Viatris Inc.|Pfizer December 2015 Phase 1
NCT02005107 Completed Drug: Venlafaxine IR and Venlafaxine XR Roux en Y Gastric Bypass|Sleeve Gastrectomy North Dakota State University|Neuropsychiatric Research Institute Fargo North Dakota December 2013 Phase 4
NCT01867255 Completed Drug: venlafaxine ER (extended-release) 75 mg Bariatric Surgery|Gastric Bypass|Roux-en-Y Gastric Bypass Mayo Clinic October 2013 Phase 1

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID