Venlafaxine

Catalog No.S5655 Synonyms: Wy 45030

Venlafaxine Chemical Structure

Molecular Weight(MW): 277.40

Venlafaxine is an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI), used to treat major depressive disorder (MDD), generalised anxiety disorder (GAD), panic disorder and social phobia.

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Biological Activity

Description Venlafaxine is an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI), used to treat major depressive disorder (MDD), generalised anxiety disorder (GAD), panic disorder and social phobia.
Targets
serotonin-norepinephrine reuptake [1]
()

Protocol

References

Solubility (25°C)

In vitro DMSO 55 mg/mL (198.26 mM)
Water Insoluble
Ethanol Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 277.40
Formula

C17H27NO2

CAS No. 93413-69-5
Storage powder
in solvent
Synonyms Wy 45030

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Definitions of molecular mass, molecular weight, molar mass and molar weight:

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Clinical Trial Information

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT03588572 Recruiting Subcortical Aphasia|Ischemic Stroke Guangzhou General Hospital of Guangzhou Military Command August 1 2018 Not Applicable
NCT03588572 Recruiting Subcortical Aphasia|Ischemic Stroke Guangzhou General Hospital of Guangzhou Military Command August 1 2018 Not Applicable
NCT03538691 Recruiting Major Depressive Disorder Otsuka Pharmaceutical Development & Commercialization Inc. July 13 2018 Phase 3
NCT03538691 Recruiting Major Depressive Disorder Otsuka Pharmaceutical Development & Commercialization Inc. July 13 2018 Phase 3
NCT03434041 Recruiting Depressive Disorder Treatment-Resistant Janssen Research & Development LLC May 25 2018 Phase 3
NCT03574792 Recruiting Stage III Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8|Stage IV Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8 Roswell Park Cancer Institute|National Cancer Institute (NCI) May 3 2018 Not Applicable

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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5-HT Receptor Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID