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TSQ Dyes chemical

Name: TSQ
Brand: Selleck Chemicals
SKU: E6881
Availability: InStock
Rating: 5 (1 reviews)

Cat.No.E6881

TSQ is a membrane‑permeant, quinoline‑based fluorescent probe widely used to image labile zinc pools and zinc‑bound proteins in live cells. TSQ predominantly forms ternary TSQ–Zn–protein adducts that emit with a blue‑shifted maximum near 470 nM, whereas the simple 2:1 Zn(TSQ)₂ complex in solution peaks closer to 490–495 nM.

Chemical Structure

Molecular Weight: 328.39

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Quality Control

Batch: E688101 DMSO]66 mg/mL]false]Ethanol]2 mg/mL]false]Water]Insoluble]false Purity: 99.14%

Cited in Nature Medicine for its top-tier quality
COA
SDS/MSDS
Datasheet

99.14

Related Targets	PROTAC Others Antineoplastic and Immunosuppressive Antibiotics ADC Cytotoxin Selection Antibiotics for Transfected Cell Antibiotics for Mammalian Cell Culture ADC Linker Molecular Glues Hydrotropic Agents Antibiotics for Plant Cell Culture
Other Dyes Inhibitors	Fluorofurimazine (FFz) CFSE (CFDA-SE) Propidium Iodide DFO Thiazolyl Blue Hoechst 33342 D-Luciferin Crystal Violet D-Luciferin sodium salt Dihydroethidium

Solubility

In vitro
Batch:

DMSO : 66 mg/mL (200.98 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Ethanol : 2 mg/mL

Water : Insoluble

Molarity Calculator

Mass	Concentration	Volume	Molecular Weight
Mass value Mass unit	Concentration value Concentration unit	Volume value Volume unit	Molecular weight (g/mol)

Dilution Calculator Molecular Weight Calculator

In vivo
Batch:

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg

Average weight of animals: g

Dosing volume per animal: μL

Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO

% Tween 80

% ddH₂O

% DMSO

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Molecular Weight	328.39	Formula	C₁₇H₁₆N₂O₃S	Storage (From the date of receipt)	3 years-20°C(in the dark) powder
CAS No.	109628-27-5	Download SDF		Storage of Stock Solutions	Solutions are unstable. Prepare fresh or purchase small, pre-packaged sizes. Repackage upon receipt.

Read more about storage stability CAS number

Mechanism of Action

References	[1] https://pubmed.ncbi.nlm.nih.gov/21774459/

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Handling Instructions

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