Travoprost

Catalog No.S3738 Synonyms: Travoprostum

Travoprost Chemical Structure

Molecular Weight(MW): 500.55

Travoprost is a PGF2a analog that was launched as an ophthalmic solution administered topically for the treatment of elevated intraocular hypertension as a result of open-angle glaucoma, a common optic neuropathy, and a leading cause of blindness. It can act as an agonist of prostaglandin F receptor.

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Biological Activity

Description Travoprost is a PGF2a analog that was launched as an ophthalmic solution administered topically for the treatment of elevated intraocular hypertension as a result of open-angle glaucoma, a common optic neuropathy, and a leading cause of blindness. It can act as an agonist of prostaglandin F receptor.
Targets
prostaglandin F receptor [1]
(HEK-293 cells)
42.3 nM(EC50)

Protocol

Solubility (25°C)

Chemical Information

Molecular Weight 500.55
Formula

C26H35F3O6

CAS No. 157283-68-6
Storage powder
in solvent
Synonyms Travoprostum

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Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT00705757 Completed Drug: latanoprost|Drug: bimatoprost|Drug: travoprost Glaucoma|Application Site Pigmentation Changes Summa Health System March 2008 Phase 4

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID