Siramesine HCl

For research use only.

Catalog No.S6756 Synonyms: Lu 28-179 HCl

Siramesine HCl Chemical Structure

CAS No. 224177-60-0

Siramesine (Lu 28-179) is a sigma receptor agonist, selective for the σ2 subtype with IC50 values of 0.12 nM and 17 nM for σ2 and σ1 receptors respectively.

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Biological Activity

Description Siramesine (Lu 28-179) is a sigma receptor agonist, selective for the σ2 subtype with IC50 values of 0.12 nM and 17 nM for σ2 and σ1 receptors respectively.
Targets
σ2R [1]
()
σ1R [1]
()
0.12 nM 17 nM

Protocol

Solubility (25°C)

In vitro DMSO 98 mg/mL (199.57 mM)
Ethanol 11 mg/mL (22.4 mM)
Water Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 491.05
Formula

C30H32ClFN2O

CAS No. 224177-60-0
Storage powder
in solvent
Synonyms Lu 28-179 HCl
Smiles C1CN(CCC12C3=CC=CC=C3CO2)CCCCC4=CN(C5=CC=CC=C54)C6=CC=C(C=C6)F.Cl

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Molarity Calculator

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Dilution Calculator

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID