Sigma Receptor
Inhibitory Selectivity
Sigma Receptor Products
| Catalog No. | Information | Product Use Citations | Product Validations |
|---|---|---|---|
| S6754New |
S1RAS1RA is a selective sigma-1 receptor (σ1R) antagonist with a reported binding affinity of Ki = 17.0 ± 7.0 nM for human σ1 receptor , selective over the sigma-2 receptor and against a panel of other 170 receptors, enzymes, transporters and ion channels. |
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| S0295New |
Anavex 2-73 HClAnavex 2-73, an aminotetrahydrofuran derivative, is a mixed muscarinic and sigma-1/σ1 Receptor agonist with IC50 of 0.86 μM. |
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| S5280 |
Dimemorfan phosphateDimemorfan is a nonnarcotic antitussive drug, acting as a potent agonist of the σ1 receptor (Ki = 151 nM). |
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| S6561New |
4-IBP4-IBP is a selective σ1 receptor agonist with a high level of affinity for the σ1 receptor (Ki = 1.7 nM) and a moderate affinity for the σ2 receptor (Ki = 25.2 nM). |
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| S6756New |
Siramesine HClSiramesine is a sigma receptor agonist, selective for the σ2 subtype with IC50 values of 0.12 nM and 17 nM for σ2 and σ1 receptors respectively. |
| Catalog No. | Information | Product Use Citations | Product Validations |
|---|---|---|---|
| S6754New |
S1RAS1RA is a selective sigma-1 receptor (σ1R) antagonist with a reported binding affinity of Ki = 17.0 ± 7.0 nM for human σ1 receptor , selective over the sigma-2 receptor and against a panel of other 170 receptors, enzymes, transporters and ion channels. |
| Catalog No. | Information | Product Use Citations | Product Validations |
|---|---|---|---|
| S0295New |
Anavex 2-73 HClAnavex 2-73, an aminotetrahydrofuran derivative, is a mixed muscarinic and sigma-1/σ1 Receptor agonist with IC50 of 0.86 μM. |
||
| S5280 |
Dimemorfan phosphateDimemorfan is a nonnarcotic antitussive drug, acting as a potent agonist of the σ1 receptor (Ki = 151 nM). |
||
| S6561New |
4-IBP4-IBP is a selective σ1 receptor agonist with a high level of affinity for the σ1 receptor (Ki = 1.7 nM) and a moderate affinity for the σ2 receptor (Ki = 25.2 nM). |
||
| S6756New |
Siramesine HClSiramesine is a sigma receptor agonist, selective for the σ2 subtype with IC50 values of 0.12 nM and 17 nM for σ2 and σ1 receptors respectively. |
