Sigma Receptor
Inhibitory Selectivity
Sigma Receptor Products
Catalog No. | Information | Product Use Citations | Product Validations |
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S0106New |
BD-1047 dihydrobromideBD-1047 dihydrobromide (HBr) is a selective functional antagonist of sigma-1 (σ1) receptor, shows antipsychotic activity in animal models predictive of efficacy in schizophrenia. |
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S0191New |
BD1063 2HCLBD1063 is a potent and selective sigma-1 receptor (σ1R) antagonist with Ki of 4.43 nM. |
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S6754 |
S1RAS1RA (E-52862) is a selective sigma-1 receptor (σ1R) antagonist with a reported binding affinity of Ki = 17.0 ± 7.0 nM for human σ1 receptor , selective over the sigma-2 receptor and against a panel of other 170 receptors, enzymes, transporters and ion channels. |
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S0295New |
Anavex 2-73 HClAnavex 2-73 (Blarcamesine, AVex-73, AE-37), an aminotetrahydrofuran derivative, is a mixed muscarinic and sigma-1/σ1 Receptor agonist with IC50 of 0.86 μM. |
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S0869New |
CarbetapentaneCarbetapentane (Pentoxyverine, CB) is an antitussive anticonvulsant nonselective sigma-1 (σ1) agonist. |
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S5280 |
Dimemorfan phosphateDimemorfan (3,17-dimethylmorphinan) is a nonnarcotic antitussive drug, acting as a potent agonist of the σ1 receptor (Ki = 151 nM). |
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S6561 |
4-IBP4-IBP is a selective σ1 receptor agonist with a high level of affinity for the σ1 receptor (Ki = 1.7 nM) and a moderate affinity for the σ2 receptor (Ki = 25.2 nM). |
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S6950New |
PRE-084 hydrochloridePRE-084 hydrochloride (HCl) is a potent, selective sigma-1 receptor (σ1, S1R) agonist with IC50 of 44 nM in the sigma receptor assay. |
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S6756 |
Siramesine HClSiramesine (Lu 28-179) is a sigma receptor agonist, selective for the σ2 subtype with IC50 values of 0.12 nM and 17 nM for σ2 and σ1 receptors respectively. |
Catalog No. | Information | Product Use Citations | Product Validations |
---|---|---|---|
S0106New |
BD-1047 dihydrobromideBD-1047 dihydrobromide (HBr) is a selective functional antagonist of sigma-1 (σ1) receptor, shows antipsychotic activity in animal models predictive of efficacy in schizophrenia. |
||
S0191New |
BD1063 2HCLBD1063 is a potent and selective sigma-1 receptor (σ1R) antagonist with Ki of 4.43 nM. |
||
S6754 |
S1RAS1RA (E-52862) is a selective sigma-1 receptor (σ1R) antagonist with a reported binding affinity of Ki = 17.0 ± 7.0 nM for human σ1 receptor , selective over the sigma-2 receptor and against a panel of other 170 receptors, enzymes, transporters and ion channels. |
Catalog No. | Information | Product Use Citations | Product Validations |
---|---|---|---|
S0295New |
Anavex 2-73 HClAnavex 2-73 (Blarcamesine, AVex-73, AE-37), an aminotetrahydrofuran derivative, is a mixed muscarinic and sigma-1/σ1 Receptor agonist with IC50 of 0.86 μM. |
||
S0869New |
CarbetapentaneCarbetapentane (Pentoxyverine, CB) is an antitussive anticonvulsant nonselective sigma-1 (σ1) agonist. |
||
S5280 |
Dimemorfan phosphateDimemorfan (3,17-dimethylmorphinan) is a nonnarcotic antitussive drug, acting as a potent agonist of the σ1 receptor (Ki = 151 nM). |
||
S6561 |
4-IBP4-IBP is a selective σ1 receptor agonist with a high level of affinity for the σ1 receptor (Ki = 1.7 nM) and a moderate affinity for the σ2 receptor (Ki = 25.2 nM). |
||
S6950New |
PRE-084 hydrochloridePRE-084 hydrochloride (HCl) is a potent, selective sigma-1 receptor (σ1, S1R) agonist with IC50 of 44 nM in the sigma receptor assay. |
||
S6756 |
Siramesine HClSiramesine (Lu 28-179) is a sigma receptor agonist, selective for the σ2 subtype with IC50 values of 0.12 nM and 17 nM for σ2 and σ1 receptors respectively. |