S-(-)-Cotinine

Catalog No.S9339

For research use only.

S-(-)-Cotinine, a constituent of tobacco products and the major metabolite of nicotine, stimulates nicotinic receptors to evoke the release of DA in a calcium-dependent manner from superfused rat striatal slices.

S-(-)-Cotinine Chemical Structure

CAS No. 486-56-6

Purity & Quality Control

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Biological Activity

Description S-(-)-Cotinine, a constituent of tobacco products and the major metabolite of nicotine, stimulates nicotinic receptors to evoke the release of DA in a calcium-dependent manner from superfused rat striatal slices.

Protocol (from reference)

Chemical Information

Molecular Weight 176.22
Formula

C10H12N2O

Density 1.110 g/mL
CAS No. 486-56-6
Storage 2 years -20°C(in the dark) liquid
Smiles CN1C(CCC1=O)C2=CN=CC=C2

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Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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