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S-(-)-Cotinine

Name: S-(-)-Cotinine
Brand: Selleck Chemicals
SKU: S9339
Availability: InStock
Rating: 5 (1 reviews)

Cat.No.S9339

S-(-)-Cotinine, a constituent of tobacco products and the major metabolite of nicotine, stimulates nicotinic receptors to evoke the release of DA in a calcium-dependent manner from superfused rat striatal slices.,

Chemical Structure

Molecular Weight: 176.22

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Quality Control

Batch: S933901 Purity: 99.86%

Cited in Nature Medicine for its top-tier quality
COA
SDS
Datasheet

99.86

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Solubility

In vitro
Batch:

Molarity Calculator

Mass	Concentration	Volume	Molecular Weight
Mass value Mass unit	Concentration value Concentration unit	Volume value Volume unit	Molecular weight (g/mol)

Dilution Calculator Molecular Weight Calculator

In vivo
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In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Average weight of animals: g

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% DMSO

% Tween 80

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Molecular Weight	176.22	Formula	C₁₀H₁₂N₂O	Storage (From the date of receipt)	2 years -20°C(in the dark) liquid
CAS No.	486-56-6	--		Storage of Stock Solutions	1 year-80°Cin solvent 1 month-20°Cin solvent

Mechanism of Action

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2024-05-22)

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
NCT06316947	Not yet recruiting	Shisha	University of Minnesota	February 1 2025	Not Applicable
NCT05836103	Not yet recruiting	Tobacco Cigarette Smoking	Johns Hopkins Bloomberg School of Public Health	July 1 2024	Not Applicable

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