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Ritalinic acid

Cat.No.S5251

Ritalinic acid (α-phenylpiperidine-2-acetic acid) is a substituted phenethylamine and an inactive major metabolite of the psychostimulant drugs methylphenidate. This compound can be biodegraded and used as a sole carbon and nitrogen source by various microbial strains originating from different environmental samples.
Ritalinic acid Chemical Structure

Chemical Structure

Molecular Weight: 219.28

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Quality Control

Batch: S525101 DMSO]0.01 mg/mL]false]Water]Insoluble]false]Ethanol]Insoluble]false Purity: 98%
98

Solubility

In vitro
Batch:

DMSO : 0.01 mg/mL (0.04 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Water : Insoluble

Ethanol : Insoluble

Molarity Calculator

Mass Concentration Volume Molecular Weight
Dilution Calculator Molecular Weight Calculator

In vivo
Batch:

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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g
μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO
%
% Tween 80
% ddH2O
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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Molecular Weight 219.28 Formula
C13H17NO2
 Storage (From the date of receipt) 3 years -20°C powder
CAS No. 19395-41-6 -- Storage of Stock Solutions

Synonyms α-phenylpiperidine-2-acetic acid Smiles C1CCNC(C1)C(C2=CC=CC=C2)C(=O)O

Mechanism of Action

References

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2024-05-22)

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT06221358 Recruiting
Attention-Deficit/ Hyperactivity Disorder (ADHD)
University of Calgary
 April 1 2024 --
NCT02147535 Completed
Carboxylesterase 1 (CES1) Genotype|CES1 Activity
Bispebjerg Hospital|The Ministry of Science Technology and Innovation Denmark|Mental Health Centre Sct. Hans (Denmark)|University of Copenhagen|The Leiden Academic Center for Drug Research (LACDR)|Duke University
 March 2014 Phase 4

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