Quinapril HCl

Catalog No.S2581 Synonyms: CI-906, PD-109452-2

Quinapril HCl  Chemical Structure

Molecular Weight(MW): 474.98

Quinapril HCl is the hydrochloride salt of quinapril that is an angiotensin-converting enzyme inhibitor with a Ki of 20 μM.

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In DMSO USD 130 In stock
USD 97 In stock
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Biological Activity

Description Quinapril HCl is the hydrochloride salt of quinapril that is an angiotensin-converting enzyme inhibitor with a Ki of 20 μM.
Targets
ACE [1]

Protocol

References

Solubility (25°C)

In vitro Water 95 mg/mL (200.0 mM)
Ethanol 95 mg/mL (200.0 mM)
DMSO 18 mg/mL (37.89 mM)

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 474.98
Formula

C25H30N2O5.HCl

CAS No. 82586-55-8
Storage powder
in solvent
Synonyms CI-906, PD-109452-2

Bio Calculators

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Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

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* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

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Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT00930722 Completed Drug: quinapril Hypertension Pfizer June 2009 --
NCT00980187 Completed Drug: Hydrochlorothiazide|Drug: Indapamide Hypertension|Type 2 Diabetes Mellitus LaborMed Pharma S.A. March 2008 Phase 4
NCT00147524 Completed Drug: quinapril|Procedure: Laser Doppler imaging Menopause|Hypertension Pfizer October 2003 Phase 4

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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RAAS Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID