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Polyethylenimine (branched)

Cat.No.E4019

Polyethylenimine (branched) (PEI branched) is a hydrophilic cationic polymer that acts as a low toxicity and efficient gene vector.
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Molecular Weight 10000 Formula

(C2H5N)x

Storage (From the date of receipt) 2 years  -20°C  liquid
CAS No. 9002-98-6 --

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Mechanism of Action

References

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2024-05-22)

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT05644821 Recruiting
Prostate Cancer
Heinrich-Heine University Duesseldorf|Marienhospital Herne|University Hospital Essen|University Hospital Bonn|Klinikum Dortmund gGbmH|University Hospital Muenster|University Hospital of Cologne|University of Cologne|Techniker Krankenkasse|Deutsche Krebsgesellschaft e.V.
2023-08-01 Not Applicable
NCT05804409 Not yet recruiting
Pancreatic Exocrine Insufficiency
Assiut University
2023-06 --
NCT05266963 Enrolling by invitation
Type 1 Diabetes
Vanderbilt University Medical Center
2022-09-02 Early Phase 1
NCT05244174 Recruiting
Pancreatic Neoplasm Malignant Head Primary|Pancreatic Exocrine Insufficiency
Hospital Clinico Universitario de Santiago
2022-01-25 Not Applicable
NCT04548778 Recruiting
Exocrine Pancreatic Insufficiency
Bühlmann Laboratories AG
2020-11-01 --
NCT01274455 COMPLETED
Pancreatic Adenocarcinoma
University Hospital, Toulouse
2010-12 PHASE1

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