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Olive oil

Cat.No.E0505

Olive oil comes from the fruits of Olea europae trees with a beneficial effect on human health, including the antioxidant activity and anti-inflammatory activity when olive oil is in regular diet.
Olive oil Chemical Structure

Chemical Structure

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Quality Control

Batch: E050501 Purity: 99%
99

Solubility

In vitro
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In vivo
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Molecular Weight Formula Storage (From the date of receipt) 2 years -20°C liquid
CAS No. 8001-25-0 -- Storage of Stock Solutions

Mechanism of Action

In vitro

Among the polyphenols of olive oil, oleuropein, hydroxytyrosol, and resveratrol possess marked antioxidant activity and reduce monocytoid cell adhesion to stimulated endothelium, as well as vascular cell adhesion molecule-1 (VCAM-1) mRNA protein expression, which is proved to be related to NF-kB and activator protein-1.
References

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2024-05-22)

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT05292833 Recruiting
Type 2 Diabetes
Assistance Publique - Hôpitaux de Paris
 July 6 2023 --
NCT05944991 Completed
Weight Gain
Bangabandhu Sheikh Mujib Medical University Dhaka Bangladesh
 December 1 2022 Not Applicable
NCT05594472 Recruiting
Pemphigus Vulgaris|Bullous Pemphigoid
Cairo University
 November 1 2022 Phase 3

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