Methyl acetoacetate

Catalog No.S3091 Synonyms: MAA, Acetoacetate methyl ester, Methyl 3-oxobutanoate, Methyl 3-oxobutyrate, Methyl acetoacetate, Methyl acetylacetate

For research use only.

Methyl acetylacetate (MAA, Acetoacetate methyl ester, Methyl 3-oxobutanoate, Methyl 3-oxobutyrate, Methyl acetoacetate, Methyl acetylacetate), an endogenous metabolite, is used as a chemical reagent used in the synthesis of pharmaceuticals.

Methyl acetoacetate Chemical Structure

CAS No. 105-45-3

Purity & Quality Control

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Biological Activity

Description

Methyl acetylacetate (MAA, Acetoacetate methyl ester, Methyl 3-oxobutanoate, Methyl 3-oxobutyrate, Methyl acetoacetate, Methyl acetylacetate), an endogenous metabolite, is used as a chemical reagent used in the synthesis of pharmaceuticals.

Protocol (from reference)

Chemical Information

Molecular Weight 116.12
Formula

C5H8O3

CAS No. 105-45-3
Storage 2 years -20°C liquid

In vivo Formulation Calculator (Clear solution)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
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as vortex, ultrasound or hot water bath can be used to aid dissolving.

Molarity Calculator

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Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04555564 Not yet recruiting Procedure: Technicium 99 MAA infusion Hemoptysis|Malignant Neoplasm|Lung Cancer Johns Hopkins University|Boston Scientific Corporation August 1 2022 Not Applicable
NCT04788095 Recruiting Behavioral: Behavioral Intervention Metastatic Renal Cell Carcinoma|Stage IV Renal Cell Cancer AJCC v8 City of Hope Medical Center|National Cancer Institute (NCI) October 15 2021 Not Applicable
NCT04584502 Not yet recruiting Behavioral: Mindful Moms Yoga Mindfulness Intervention Opioid-use Disorder Dartmouth-Hitchcock Medical Center|National Center for Complementary and Integrative Health (NCCIH)|Trustees of Dartmouth College September 2021 Not Applicable

(data from https://clinicaltrials.gov, updated on 2021-09-06)

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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