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Methyl acetoacetate

Name: Methyl acetoacetate
Brand: Selleck Chemicals
SKU: S3091
Availability: InStock
Rating: 5 (1 reviews)

Cat.No.S3091

Methyl acetylacetate (MAA, Acetoacetate methyl ester, Methyl 3-oxobutanoate, Methyl 3-oxobutyrate, Methyl acetoacetate, Methyl acetylacetate), an endogenous metabolite, is used as a chemical reagent used in the synthesis of pharmaceuticals.

Chemical Structure

Molecular Weight: 116.12

Jump to Mechanism of Action Solubility Chemical Information, Storage & Stability

Quality Control

Batch: S309101 Purity: 99.39%

99.39

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Chemical Information, Storage & Stability

Molecular Weight	116.12	Formula	C₅H₈O₃	Storage (From the date of receipt)	2 years -20°C liquid
CAS No.	105-45-3	--		Storage of Stock Solutions	1 year-80°Cin solvent 1 month-20°Cin solvent
Synonyms	MAA, Acetoacetate methyl ester, Methyl 3-oxobutanoate, Methyl 3-oxobutyrate, Methyl acetoacetate, Methyl acetylacetate			Smiles	COC(=O)CC(C)=O

Solubility

In vitro
Batch:

Molarity Calculator

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Dilution Calculator Molecular Weight Calculator

In vivo
Batch:

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg Average weight of animals: g Dosing volume per animal:μL Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

%DMSO+ %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Mechanism of Action

References	[1] https://pubmed.ncbi.nlm.nih.gov/25255751/

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2024-05-22)

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
NCT06377215	Not yet recruiting	Hearing Impairment Sensorineural\|Spatial Perception\|Aging\|Hearing Aids	University of South Florida\|National Institute on Deafness and Other Communication Disorders (NIDCD)	April 15 2024	--
NCT06289426	Recruiting	Perceived Stress\|Depression\|Anxiety\|Mindfulness\|Self-Compassion\|Compassion\|Work Engagement\|Productivity\|Heart Rate Variability\|Mental Wellbeing\|Musculoskeletal Pain	Kingston University	February 15 2024	Not Applicable
NCT06130878	Completed	Cognitive Impairment	University of Jaén	January 8 2024	Not Applicable
NCT06055322	Not yet recruiting	Suicide\|Depression\|Caregiver Burden\|Physical Health\|Inflammation	Texas Tech University	January 1 2024	Not Applicable
NCT06402240	Recruiting	Substance Use Disorders\|Alcohol Use Disorder\|Depression\|Anxiety	University of Windsor\|Centre for Addiction and Mental Health	January 1 2024	Not Applicable

Tech Support

Handling Instructions

Tel: +1-832-582-8158 Ext:3

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