Meglumine

Catalog No.S1974

For research use only.

Meglumine is an amino sugar derived from sorbitol for THP-1 cells with IC50 of 22 μg/mL.

Meglumine Chemical Structure

CAS No. 6284-40-8

Purity & Quality Control

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Biological Activity

Description Meglumine is an amino sugar derived from sorbitol for THP-1 cells with IC50 of 22 μg/mL.

Protocol (from reference)

Solubility (25°C)

In vitro

DMSO 39 mg/mL
(199.78 mM)
Water 39 mg/mL
(199.78 mM)
Ethanol Insoluble

Chemical Information

Molecular Weight 195.21
Formula

C7H17NO5

CAS No. 6284-40-8
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles CNCC(C(C(C(CO)O)O)O)O

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT03937921 Recruiting Drug: Gadavist 15Ml Solution for Injection Myocardial Perfusion Imaging|Magnetic Resonance Imaging Medical University of South Carolina|Guerbet July 3 2019 --
NCT02593370 Completed Drug: Lidocaine-epinephrine added gadoterate meglumine Hip Fractures|Anesthesia Local|Pain Perioperative Thomas F. Bendtsen|AP Moeller Foundation|Aarhus University Hospital|University of Aarhus October 2015 Phase 1
NCT01301924 Completed Drug: Meglumine antimoniate Cutaneous Leishmaniasis Oswaldo Cruz Foundation|Rio de Janeiro State Research Supporting Foundation (FAPERJ)|Conselho Nacional de Desenvolvimento Científico e Tecnológico October 2008 Phase 2|Phase 3
NCT01301937 Unknown status Drug: Meglumine antimoniate Mucosal Leishmaniasis|Mucocutaneous Leishmaniasis Oswaldo Cruz Foundation|Rio de Janeiro State Research Supporting Foundation (FAPERJ)|Conselho Nacional de Desenvolvimento Científico e Tecnológico October 2008 Phase 2|Phase 3

(data from https://clinicaltrials.gov, updated on 2022-01-17)

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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