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Isopropyl myristate

Name: Isopropyl myristate
Brand: Selleck Chemicals
SKU: S2428
Rating: 5 (1 reviews)

Synonyms: IPM

Catalog No.S2428 Purity: 99%

Isopropyl myristate (IPM) is used as a substitute for natural oils in cosmetics and a co-solvent with skin penetration enhancement properties of active ingredients in many topical and transdermal preparations. It affects the lamellar lipid assembly in terms of bilayer perturbation and disordering.

Isopropyl myristate Chemical Structure

CAS: 110-27-0

Purity & Quality Control

Batch: S242801 Purity: 99%

Isopropyl myristate Related Products

Biological Activity

Description	Isopropyl myristate (IPM) is used as a substitute for natural oils in cosmetics and a co-solvent with skin penetration enhancement properties of active ingredients in many topical and transdermal preparations. It affects the lamellar lipid assembly in terms of bilayer perturbation and disordering.

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2024-01-11)
NCT05981066	Recruiting	Advanced Hepatocellular Carcinoma	Peking Union Medical College Hospital	July 10 2023	Not Applicable
NCT03319927	Recruiting	Children Only\|Risk Reduction\|Environmental Exposure	University of California San Francisco\|National Institute of Environmental Health Sciences (NIEHS)\|University of California Berkeley\|Oregon State University	October 9 2017	Not Applicable
NCT02020226	Unknown status	Solid Tumors	Threshold Pharmaceuticals	November 2013	Phase 1
NCT01833546	Completed	Solid Tumor\|Pancreatic Cancer	Merck KGaA Darmstadt Germany\|Threshold Pharmaceuticals	April 18 2013	Phase 1

References

Chemical Information & Solubility

Molecular Weight	270.45	Formula	C₁₇H₃₄O₂
CAS No.	110-27-0	SDF	--
Density	0.85 g/mL at 25 °C
Smiles	CCCCCCCCCCCCCC(=O)OC(C)C
Storage (From the date of receipt)	2 years -20°C liquid	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	2 years -20°C liquid		1 month-20°Cin solvent

In vitro
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In vivo
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In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg Average weight of animals: g Dosing volume per animal:μL Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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