Iohexol

Name: Iohexol
Brand: Selleck Chemicals
SKU: S4531
Rating: 5 (1 reviews)

Synonyms: Omnipaque

Catalog No.S4531 Purity: 99.81%

Iohexol (Omnipaque) is a radiographic contrast agent that can be used as an exogenous filtration marker for accurate glomerular filtration rate (GFR) estimates.

Iohexol Chemical Structure

CAS: 66108-95-0

Purity & Quality Control

Batch: S453101 DMSO] 100 mg/mL] false] Water] 100 mg/mL] false] Ethanol] 100 mg/mL] false Purity: 99.81%

99.81

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Biological Activity

Description	Iohexol (Omnipaque) is a radiographic contrast agent that can be used as an exogenous filtration marker for accurate glomerular filtration rate (GFR) estimates.

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2024-01-11)
NCT05136963	Not yet recruiting	Kidney Function Test	Centre Hospitalier Universitaire de Saint Etienne	June 2024	Phase 1
NCT05536804	Recruiting	Overweight\|Obesity\|Chronic Kidney Disease\|Type 2 Diabetes\|T2D	Eli Lilly and Company	February 8 2023	Phase 2
NCT04993872	Active not recruiting	HIV-infected Patient Kidney Transplant Recipient	Institut de Médecine et d''Epidémiologie Appliquée - Fondation Internationale Léon M''Ba\|LAMBERT ASSOUMOU/ UNITE 1136 INSERM\|Sebastien GALLIEN/Henri Mondor University Hospital- Infectiology Department\|THOMAS STEHL/ HENRI MONDOR HOSPITAL-Department of Nephrology	September 29 2022	Phase 4
NCT05460169	Recruiting	Uncontrolled Hypertension\|Autosomal Dominant Polycystic Kidney Disease\|Renal Denervation	University of Erlangen-Nürnberg Medical School	June 14 2022	Not Applicable
NCT05307172	Not yet recruiting	Chronic Kidney Diseases\|Diabetes\|Obesity	Institut National de la Santé Et de la Recherche Médicale France\|Centre Hospitalier Universitaire Amiens\|Biobanque de Picardie	May 3 2022	--

References

[1] Gunnar Nordin, et al. Clin Chem Lab Med. 2019 Jun 26;57(7):1006-1011.

Chemical Information & Solubility

Molecular Weight	821.14	Formula	C₁₉H₂₆I₃N₃O₉
CAS No.	66108-95-0	SDF	--
Smiles	CC(=O)N(CC(O)CO)C1=C(I)C(=C(I)C(=C1I)C(=O)NCC(O)CO)C(=O)NCC(O)CO
Storage (From the date of receipt)	3 years-21°C powder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years-21°C powder		1 month-20°Cin solvent

In vitro
Batch:

DMSO : 100 mg/mL ( (121.78 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 100 mg/mL

Ethanol : 100 mg/mL

Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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