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Iodixanol

Cat.No.S5218

Iodixanol is a nonionic hydrophilic compound commonly used as a contrast agent during coronary angiography.
Iodixanol Chemical Structure

Chemical Structure

Molecular Weight: 1550.18

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Quality Control

Batch: Purity: 99.96%
99.96

Solubility

In vitro
Batch:

DMSO : 100 mg/mL (64.5 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Molarity Calculator

Mass Concentration Volume Molecular Weight
Dilution Calculator Molecular Weight Calculator

In vivo
Batch:

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg
g
μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO
%
% Tween 80
% ddH2O
% DMSO
+
%

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Molecular Weight 1550.18 Formula

C35H44I6N6O15

Storage (From the date of receipt)
CAS No. 92339-11-2 -- Storage of Stock Solutions

Synonyms N/A Smiles CC(=O)N(CC(O)CN(C(C)=O)C1=C(I)C(=C(I)C(=C1I)C(=O)NCC(O)CO)C(=O)NCC(O)CO)C2=C(I)C(=C(I)C(=C2I)C(=O)NCC(O)CO)C(=O)NCC(O)CO

Mechanism of Action

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2024-05-22)

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT01580046 Unknown status
Kidney Failure Chronic
Yong Huo|Peking University First Hospital
April 2012 Phase 4
NCT01475097 Completed
Drug Safety
GE Healthcare|i3 Statprobe
October 2011 Phase 4
NCT01376089 Completed
Patient Comfort and Safety
GE Healthcare|i3 Statprobe
May 2011 Phase 4
NCT00209417 Terminated
Renal Insufficiency|Diabetes Mellitus
GE Healthcare|ABX CRO|Examination Management Services Inc.|Covance|Quintiles Inc.|Averion International Corporation
June 2005 Phase 4

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