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Indigo carmine

Cat.No.S5653

Indigo carmine (Indigotine, 5,5′-indigodisulfonic acid sodium salt, Brilliant Indigo) is an indicator at pH 11.5-14, changing from blue to yellow. It has a role as a food colouring and a histological dye.
Indigo carmine Chemical Structure

Chemical Structure

Molecular Weight: 466.35

Jump to Mechanism of Action Solubility Chemical Information, Storage & Stability

Quality Control

Batch: S565301 DMSO]93 mg/mL]false]Water]93 mg/mL]false]]]false Purity: 98%
98

Chemical Information, Storage & Stability

Molecular Weight 466.35 Formula

C16H8N2Na2O8S2

 Storage (From the date of receipt) 3 years -20°C powder
CAS No. 860-22-0 -- Storage of Stock Solutions

Synonyms Indigotine, 5,5′-indigodisulfonic acid sodium salt, Brilliant Indigo Smiles C1=CC2=C(C=C1S(=O)(=O)[O-])C(=C(N2)C3=NC4=C(C3=O)C=C(C=C4)S(=O)(=O)[O-])O.[Na+].[Na+]

Solubility

In vitro
Batch:

DMSO : 93 mg/mL (199.42 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Water : 93 mg/mL

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo
Batch:

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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%
% Tween 80
% ddH2O
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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Mechanism of Action

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2024-05-22)

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT02570516 Completed
Lynch Syndrome
Assistance Publique - Hôpitaux de Paris|ARC Foundation for Cancer Research
 November 2015 Not Applicable
NCT01914445 Unknown status
Inflammatory Bowel Diseases
Hillel Yaffe Medical Center
 August 2013 Not Applicable
NCT01901510 Completed
Colonic Polyps
Mayo Clinic
 May 2013 Phase 1
NCT00961948 Completed
Ulcerative Colitis
Mayo Clinic
 June 2009 --

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