Glucosamine

Catalog No.S6400 Synonyms: 2-amino-2-deoxy-D-glucose

For research use only.

Glucosamine (2-amino-2-deoxy-D-glucose) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids. It is commonly used as a treatment for osteoarthritis. Glucosamine(GS) treatment selectively downregulates HIF-1α at the protein level in YD-8 cells via interference of production of the citric acid cycle metabolites.

Glucosamine Chemical Structure

CAS No. 3416-24-8

Selleck's Glucosamine has been cited by 1 Publication

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Description Glucosamine (2-amino-2-deoxy-D-glucose) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids. It is commonly used as a treatment for osteoarthritis. Glucosamine(GS) treatment selectively downregulates HIF-1α at the protein level in YD-8 cells via interference of production of the citric acid cycle metabolites.

Protocol (from reference)

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight 179.17
Formula

C6H13NO5

CAS No. 3416-24-8
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles NC(C=O)C(O)C(O)C(O)CO

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Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT05305937 Not yet recruiting Device: MRI scan Malignant Tumor of Breast|Benign Breast Lumps|High-Risk Breast Cancer Meir Medical Center|Tel Aviv University May 2022 Not Applicable
NCT05038436 Recruiting Device: Polyglucosamine L112 Cholesterol Lowering Certmedica International GmbH|University Hospital Bonn September 16 2021 Not Applicable
NCT03827161 Completed Dietary Supplement: Glucosamine|Other: Placebo Healthy Subject|Overweight Fred Hutchinson Cancer Center August 1 2017 Phase 1
NCT03743896 Completed Drug: Transdermal Glucosamine Cream Osteoarthritis Knee Lynk Biotechnologies Pte Ltd|T&T Family Health Clinic and Surgery Singapore|Temasek Polytechnic School of Applied Science Singapore May 18 2016 Phase 4
NCT02882438 Recruiting Drug: infected group|Drug: control group Foot Infection Tinea Pedis Ahmed A. H. Abdellatif|Al-Azhar University January 2016 Phase 1

(data from https://clinicaltrials.gov, updated on 2022-08-01)

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