Gibberellic acid

Catalog No.S4766 Synonyms: Gibberellin, Gibberellin A3, GA3

For research use only.

Gibberellic acid (Gibberellin, Gibberellin A3, GA3, GA), a plant hormone stimulating plant growth and development, is a tetracyclic di-terpenoid compound.

Gibberellic acid Chemical Structure

CAS No. 77-06-5

Purity & Quality Control

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Biological Activity

Description Gibberellic acid (Gibberellin, Gibberellin A3, GA3, GA), a plant hormone stimulating plant growth and development, is a tetracyclic di-terpenoid compound.
In vivo Gibberellic acid (GA3) acts as an agonist of steroidogenesis in male rats. Administration of GA3 to rat causes reduction in liver carbohydrates, total protein content, serum levels of aspartate and alanine amino transferases and alkaline phosphatase in a time- and dose- dependent mannner. It is reported that GA3 causes hepatonephrotoxicity, oxidative stress and DNA damage in rat testis. Abscisic acid and GA3 have been found to affect sexual differentiation and other physiological characteristics in mice[1]. Gibberellic acid is tested by various routes in mice for its acute toxicity and found to be essentially nontoxic. Both subacute toxicity in mice and subchronic toxicity in dogs and rats show the compound to be asymptomatic and free of pathologic changes, histologically. The highest observed nontoxic (and asymptomatic) doses in mice as determined by acute toxicity testing are as follows: 4 Gm./Kg., intravenously; 15 Gm./Kg., orally; and 2 Gm./Kg., intraperitoneally[2].

Protocol (from reference)

Animal Research:[1]
  • Animal Models: normal and diabetic Wistar male rats
  • Dosages: 150 μg/day
  • Administration: Oral administration

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight 346.37
Formula

C19H22O6

CAS No. 77-06-5
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O

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Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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