Gibberellic acid

Synonyms: Gibberellin, Gibberellin A3, GA3

Gibberellic acid (Gibberellin, Gibberellin A3, GA3, GA), a plant hormone stimulating plant growth and development, is a tetracyclic di-terpenoid compound.

Gibberellic acid Chemical Structure

Gibberellic acid Chemical Structure

CAS: 77-06-5

Purity & Quality Control

Batch: S476601 DMSO] 69 mg/mL] false] ] ] false] ] ] false Purity: 98%
98

Gibberellic acid Related Products

Biological Activity

Description Gibberellic acid (Gibberellin, Gibberellin A3, GA3, GA), a plant hormone stimulating plant growth and development, is a tetracyclic di-terpenoid compound.
In Vivo
In vivo Gibberellic acid (GA3) acts as an agonist of steroidogenesis in male rats. Administration of GA3 to rat causes reduction in liver carbohydrates, total protein content, serum levels of aspartate and alanine amino transferases and alkaline phosphatase in a time- and dose- dependent mannner. It is reported that GA3 causes hepatonephrotoxicity, oxidative stress and DNA damage in rat testis. Abscisic acid and GA3 have been found to affect sexual differentiation and other physiological characteristics in mice[1]. Gibberellic acid is tested by various routes in mice for its acute toxicity and found to be essentially nontoxic. Both subacute toxicity in mice and subchronic toxicity in dogs and rats show the compound to be asymptomatic and free of pathologic changes, histologically. The highest observed nontoxic (and asymptomatic) doses in mice as determined by acute toxicity testing are as follows: 4 Gm./Kg., intravenously; 15 Gm./Kg., orally; and 2 Gm./Kg., intraperitoneally[2].
Animal Research Animal Models normal and diabetic Wistar male rats
Dosages 150 μg/day
Administration Oral administration

Chemical Information & Solubility

Molecular Weight 346.37 Formula

C19H22O6

CAS No. 77-06-5 SDF Download Gibberellic acid SDF
Smiles CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 69 mg/mL ( (199.2 mM); Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)


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In vivo
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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