Home Others Others Gadoteridol

research use only

Gadoteridol

Cat.No.E0006

Gadoteridol (ProHance, SQ-32692, Gd-HP-DO3A) is a nonionic contrast agent for magnetic resonance imaging (MRI).
Gadoteridol Chemical Structure

Chemical Structure

Molecular Weight: 558.68

Jump to

Quality Control

Batch: E000601 DMSO]100 mg/mL]false]Water]100 mg/mL]false]Ethanol]100 mg/mL]false Purity: 99.23%
99.23

Solubility

In vitro
Batch:

DMSO : 100 mg/mL (178.99 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Water : 100 mg/mL

Ethanol : 100 mg/mL

Molarity Calculator

Mass Concentration Volume Molecular Weight
Dilution Calculator Molecular Weight Calculator

In vivo
Batch:

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg
g
μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO
%
% Tween 80
% ddH2O
% DMSO
+
%

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Molecular Weight 558.68 Formula

C17H29GdN4O7

 Storage (From the date of receipt) 3 years -20°C powder
CAS No. 120066-54-8 -- Storage of Stock Solutions

Synonyms ProHance, SQ-32692, Gd-HP-DO3A SMILES [Gd+3].CC(O)CN1CCN(CCN(CCN(CC1)CC([O-])=O)CC([O-])=O)CC([O-])=O

Read more about storage stability stock solution CAS number SMILES

Mechanism of Action

References

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2026-01-22)

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT04373564 RECRUITING
Motor Function; Cognitive Function; Contrast Media
Guerbet
 2021-03-24 PHASE4
NCT04248543 COMPLETED
Spinal Metastases
Duke University
 2020-12-22
NCT05915728 COMPLETED
Contrast Enhancement in Magnetic Resonance Imaging; Non-central Nervous System Pathology
Bayer
 2023-07-24 PHASE3
NCT05915702 COMPLETED
Contrast Enhancement in Magnetic Resonance Imaging; Central Nervous System Pathology
Bayer
 2023-07-24 PHASE3
NCT05357833 COMPLETED
Secondary Progressive Multiple Sclerosis; Multiple Sclerosis, Secondary Progressive; Multiple Sclerosis
University of Utah
 2022-06-01 EARLY_PHASE1
NCT04608812 TERMINATED
Glioma, Malignant; High Grade Glioma; Glioblastoma; Glioblastoma Multiforme; Anaplastic Astrocytoma
OncoSynergy, Inc.
 2021-03-02 PHASE1

Read more about Clinical Trials

Tech Support

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.