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Edetate calcium disodium

Cat.No.S5721

Edetate (EDTA) calcium disodium is a chelating agent that is primarily used for the management of severe lead poisoning.
Edetate calcium disodium Chemical Structure

Chemical Structure

Molecular Weight: 374.27

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Quality Control

Batch: S572101 Water]75 mg/mL]false]DMSO]Insoluble]false]]]false Purity: 98%
98

Solubility

In vitro
Batch:

Water : 75 mg/mL

DMSO : Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

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In vivo
Batch:

In vivo Formulation Calculator (Clear solution)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Molecular Weight 374.27 Formula

C10H12CaN2Na2O8

Storage (From the date of receipt) 3 years -20°C powder
CAS No. 62-33-9 -- Storage of Stock Solutions

Synonyms EDTA calcium disodium Smiles C(CN(CC(=O)[O-])CC(=O)[O-])N(CC(=O)[O-])CC(=O)[O-].[Na+].[Na+].[Ca+2]

Mechanism of Action

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2024-05-22)

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT02421029 Withdrawn
Heavy Metal Toxicity
Mt. Sinai Medical Center Miami
July 2017 Phase 4
NCT00378781 Withdrawn
Cancer
M.D. Anderson Cancer Center|National Cancer Institute (NCI)
Not Applicable

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