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Diphenylterazine (DTZ) Dyes chemical

Name: Diphenylterazine (DTZ)
Brand: Selleck Chemicals
SKU: S0866
Availability: InStock
Rating: 5 (1 reviews)

Cat.No.S0866

Diphenylterazine (DTZ), a synthetic coelenterazine analog, is a bioluminescence agent that yields very little background alone, leading to excellent signal-to-background ratios. Its treatment can track tumor growth in a xenograft NU/J mouse model.

Chemical Structure

Molecular Weight: 377.44

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Quality Control

Batch: S086601 DMF]20 mg/mL]false]Ethanol]2 mg/mL]false]Water]Insoluble]false Purity: 99.20%

Cited in Nature Medicine for its top-tier quality
COA
NMR
HPLC
SDS
Datasheet

99.20

Related Targets	PROTAC Others Antineoplastic and Immunosuppressive Antibiotics ADC Cytotoxin Selection Antibiotics for Transfected Cell Antibiotics for Mammalian Cell Culture ADC Linker Molecular Glues Hydrotropic Agents Antibiotics for Plant Cell Culture
Other Dyes Inhibitors	Fluorofurimazine (FFz) CFSE Propidium Iodide DFO D-Luciferin Thiazolyl Blue Crystal Violet Hoechst 33342 WST-8 D-Luciferin sodium salt

Solubility

In vitro
Batch:

DMF : 20 mg/mL

Ethanol : 2 mg/mL

Water : Insoluble

Molarity Calculator

Mass	Concentration	Volume	Molecular Weight
Mass value Mass unit	Concentration value Concentration unit	Volume value Volume unit	Molecular weight (g/mol)

Dilution Calculator Molecular Weight Calculator

In vivo
Batch:

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg

Average weight of animals: g

Dosing volume per animal: μL

Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO

% Tween 80

% ddH₂O

% DMSO

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Molecular Weight	377.44	Formula	C₂₅H₁₉N₃O	Storage (From the date of receipt)	3 years -20°C powder
CAS No.	344940-63-2	--		Storage of Stock Solutions	1 year-80°Cin solvent 1 month-20°Cin solvent

Mechanism of Action

References	[1] https://pubmed.ncbi.nlm.nih.gov/28869756/ [2] https://pubmed.ncbi.nlm.nih.gov/28869756/ [3] https://pubmed.ncbi.nlm.nih.gov/30969754/

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2024-05-22)

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
NCT00263484	Completed	Multiple Myeloma	Gleneagles Hospital\|Singapore General Hospital\|National Cancer Centre Singapore\|Tan Tock Seng Hospital\|Seoul National University Hospital\|Asan Medical Center\|Samsung Medical Center\|Chonnam National University Hospital\|Christian Medical College Vellore India\|Tata Memorial Hospital	December 2005	Phase 2

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Handling Instructions

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