Home Others Dyes chemical Diphenylterazine (DTZ) For research use only.

Diphenylterazine (DTZ)

Diphenylterazine (DTZ), a synthetic coelenterazine analog, is a bioluminescence agent. Diphenylterazine alone yields very little background, leading to excellent signal-to-background ratios. Diphenylterazine treatment can track tumor growth in a xenograft NU/J mouse model.

Diphenylterazine (DTZ) Chemical Structure

Diphenylterazine (DTZ) Chemical Structure

CAS: 344940-63-2

Purity & Quality Control

Batch: S086601 DMF] 20 mg/mL] false] Ethanol] 2 mg/mL] false] Water] Insoluble] false Purity: 99.20%
99.20

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Biological Activity

Description Diphenylterazine (DTZ), a synthetic coelenterazine analog, is a bioluminescence agent. Diphenylterazine alone yields very little background, leading to excellent signal-to-background ratios. Diphenylterazine treatment can track tumor growth in a xenograft NU/J mouse model.
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT00263484 Completed
Multiple Myeloma
Gleneagles Hospital|Singapore General Hospital|National Cancer Centre Singapore|Tan Tock Seng Hospital|Seoul National University Hospital|Asan Medical Center|Samsung Medical Center|Chonnam National University Hospital|Christian Medical College Vellore India|Tata Memorial Hospital
 December 2005 Phase 2

Chemical Information & Solubility

Molecular Weight 377.44 Formula

C25H19N3O
CAS No. 344940-63-2 SDF --
Smiles O=C1N2C=C(NC(=C2N=C1CC3=CC=CC=C3)C4=CC=CC=C4)C5=CC=CC=C5
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMF : 20 mg/mL

Ethanol : 2 mg/mL

Water : Insoluble


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In vivo
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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