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Creatinine

Cat.No.S3102

Creatinine(NSC13123) is a break-down product of creatine phosphate in muscle, and is usually produced at a fairly constant rate by the body.
Creatinine Chemical Structure

Chemical Structure

Molecular Weight: 113.12

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Quality Control

Batch: S310201 Water]23 mg/mL]false]DMSO]Insoluble]false]Ethanol]Insoluble]false Purity: 99.90%
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99.90

Solubility

In vitro
Batch:

Water : 23 mg/mL

DMSO : Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Ethanol : Insoluble

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In vivo
Batch:

In vivo Formulation Calculator (Clear solution)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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%
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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Molecular Weight 113.12 Formula

C4H7N3O

 Storage (From the date of receipt)
CAS No. 60-27-5 Download SDF Storage of Stock Solutions

Synonyms NSC13123 Smiles CN1CC(=O)N=C1N

Mechanism of Action

In vitro

Creatinine is a break-down product of creatine phosphate in muscle, and is usually produced at a fairly constant rate by the body. This compound's levels in blood and urine may be used to calculate the creatinine clearance (CrCl), which reflects the glomerular filtration rate (GFR), an important clinical index of renal function.
References

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2024-05-22)

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT04598516 Withdrawn
Acute Kidney Injury (Nontraumatic)|Contrast-induced Nephropathy|Renal Insufficiency
Maastricht University Medical Center
 November 1 2097 --
NCT04597892 Withdrawn
Renal Insufficiency|Acute Kidney Injury|Contrast-induced Nephropathy
Maastricht University Medical Center
 May 1 2097 --
NCT06226662 Not yet recruiting
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
NovelMed Therapeutics
 June 2025 Phase 2
NCT05847179 Not yet recruiting
Werner Syndrome
PRG Science & Technology Co. Ltd.
 January 1 2025 Phase 2
NCT05935293 Not yet recruiting
Renal Transplantation|Dexmedetomidine
Eduardo Schiffer|University Hospital Geneva
 December 1 2024 Phase 4

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