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Chondroitin 4-sulfate

Cat.No.S9004

Chondroitin 4-sulfate is an important structural component of cartilage and has been used as a dietary supplement to treat symptoms of joint discomfort.
Chondroitin 4-sulfate Chemical Structure

Chemical Structure

Molecular Weight:

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Quality Control

Chemical Information, Storage & Stability

Molecular Weight Formula

H2O4S.Unspecified

 Storage (From the date of receipt) 3 years -20°C powder
CAS No. 24967-93-9 -- Storage of Stock Solutions

Synonyms N/A Smiles CC(=O)NC1C(C(C(OC1O)OS(=O)(=O)O)O)OC2C(C(C(C(O2)C(=O)O)O)O)O

Solubility

In vitro
Batch:

Water : 50 mg/mL

DMSO : Insoluble ( Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : Insoluble

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo
Batch:

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

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% DMSO % % Tween 80 % ddH2O
%DMSO %

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Mechanism of Action

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2024-05-22)

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT05306054 Recruiting
Anterior Cruciate Ligament Injuries|Anterior Cruciate Ligament Rupture|Anterior Cruciate Ligament Tear|Post-traumatic Osteoarthritis|Anterior Cruciate Ligament Reconstruction
University of Bath|Versus Arthritis
 June 1 2022 --
NCT05323370 Completed
Lymphangioleiomyomatosis|Tuberous Sclerosis Complex
University Hospital Tours
 May 31 2022 --
NCT04507074 Active not recruiting
Low Back Pain|Obesity
Poznan University of Physical Education
 September 1 2020 Not Applicable
NCT04618237 Enrolling by invitation
Hemophilia|Arthropathy
Taipei Medical University Hospital|Sanofi
 July 20 2020 --

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