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Butylated hydroxytoluene

Cat.No.S6202

Butylated hydroxytoluene (dibutylhydroxytoluene, Dibutylated hydroxytoluene, AO-29, BHT) is a lipophilic organic compound that is useful for its antioxidant properties.
Butylated hydroxytoluene Chemical Structure

Chemical Structure

Molecular Weight: 220.35

Quality Control

Batch: S620201 DMSO]44 mg/mL]false]]]false]]]false Purity: 99.98%
99.98

Chemical Information, Storage & Stability

Molecular Weight 220.35 Formula

C15H24O

Storage (From the date of receipt) 3 years -20°C powder
CAS No. 128-37-0 -- Storage of Stock Solutions

Synonyms dibutylhydroxytoluene, Dibutylated hydroxytoluene, AO-29, BHT Smiles CC1=CC(=C(C(=C1)C(C)(C)C)O)C(C)(C)C

Solubility

In vitro
Batch:

DMSO : 44 mg/mL (199.68 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo
Batch:

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg
g
μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO
%
% Tween 80
% ddH2O
% DMSO
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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Mechanism of Action

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2024-05-22)

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT04618302 Completed
Healthy
Thomas Radtke|University of Zurich
October 19 2020 --
NCT00382629 Completed
Relapsing Remitting Multiple Sclerosis
Bayhill Therapeutics
February 2006 Phase 2
NCT00103974 Completed
Multiple Sclerosis
Bayhill Therapeutics
July 2004 Phase 1

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