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Benzyl alcohol

Name: Benzyl alcohol
Brand: Selleck Chemicals
SKU: S4600
Availability: InStock
Rating: 5 (1 reviews)

Cat.No.S4600

Benzyl alcohol (Phenylmethanol, Benzenemethanol, Phenylcarbinol, Benzoyl alcohol) is used as a local anesthetic. Also, it is used in the manufacture of other benzyl compounds, as a pharmaceutic aid, and in perfumery and flavoring.

Chemical Structure

Molecular Weight: 108.14

Jump to Mechanism of Action Solubility Chemical Information, Storage & Stability

Quality Control

Batch: S460001 Purity: 99.95%

99.95

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Chemical Information, Storage & Stability

Molecular Weight	108.14	Formula	C₇H₈O	Storage (From the date of receipt)	2 years -20°C liquid
CAS No.	100-51-6	Download SDF		Storage of Stock Solutions	1 year-80°Cin solvent 1 month-20°Cin solvent
Synonyms	Phenylmethanol, Benzenemethanol, Phenylcarbinol, Benzoyl alcohol			Smiles	C1=CC=C(C=C1)CO

Solubility

In vitro
Batch:

Molarity Calculator

Mass	Concentration	Volume	Molecular Weight
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Dilution Calculator Molecular Weight Calculator

In vivo
Batch:

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg Average weight of animals: g Dosing volume per animal:μL Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

%DMSO+ %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Mechanism of Action

In vitro	Benzyl alcohol up to 50 mM affects primarily the inner leaflet of the red blood cell membrane and that higher concentrations affect both leaflets. These increases in membrane fluidity are not associated with changes in membrane viscoelasticity^[2].
References	[1] https://pubmed.ncbi.nlm.nih.gov/3761172/ [2] https://pubmed.ncbi.nlm.nih.gov/4005233/

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2024-05-22)

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
NCT05310734	Recruiting	Scabies	ParaPRO LLC\|Concentrics Research\|Iqvia Pty Ltd\|Medpace Inc.\|Inotiv Laboratories\|BioAgilytix	March 4 2022	Phase 4
NCT02485717	Completed	Scabies	ParaPRO LLC\|Concentrics Research	May 2 2017	Phase 3
NCT01660321	Completed	Pediculosis	ParaPRO LLC	September 2011	Phase 4

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