For research use only.
Catalog No.S2361 Synonyms: Stigmasterin
CAS No. 83-48-7
Stigmasterol is an unsaturated plant sterol that exhibits anti-cancer, anti-pyretic, anti-inflammatory and immune-modulating effects.
Purity & Quality Control
|Description||Stigmasterol is an unsaturated plant sterol that exhibits anti-cancer, anti-pyretic, anti-inflammatory and immune-modulating effects.|
Stigmasterol is an unsaturated plant sterol occurring in the plant fats or oils of soybean, calabar bean, and rape seed, and in a number of medicinal herbs, including the Chinese herbs Ophiopogon japonicus (Mai men dong) and American Ginseng.  Stigmasterol(Stigmasterin) is used as a precursor in the manufacture of synthetic progesterone,  a valuable human hormone that plays an important physiological role in the regulatory and tissue rebuilding mechanisms related to estrogen effects, as well as acting as an intermediate in the biosynthesis of androgens, estrogens, and corticoids. It is also used as the precursor of vitamin D3.  Research has indicated that stigmasterol may be useful in prevention of certain cancers, including ovarian, prostate, breast, and colon cancers.
|In vitro||Ethanol||2 mg/mL warmed (4.84 mM)|
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
In vivo Formulation Calculator (Clear solution)
|Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)|
|Dosage||mg/kg||Average weight of animals||g||Dosing volume per animal||ul||Number of animals|
|Step 2: Enter the in vivo formulation ()|
|% DMSO % % Tween 80 % ddH2O|
Working concentration： mg/ml；
Method for preparing DMSO master liquid: ： mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL，)
Method for preparing in vivo formulation：Take μL DMSO master liquid, next addμL PEG300， mix and clarify, next addμL Tween 80，mix and clarify, next add μL ddH2O，mix and clarify.
1.Please make sure the liquid is clear before adding the next solvent.
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Clinical Trial Information
|NCT Number||Recruitment||interventions||Conditions||Sponsor/Collaborators||Start Date||Phases|
|NCT04555044||Recruiting||Drug: Clinolipid|Drug: Intralipid||Essential Fatty Acid Deficiency (EFAD)||Baxter Healthcare Corporation||January 22 2021||Phase 4|
|NCT03563222||Recruiting||Drug: Smoflipid|Drug: Intralipid 20%||Malnutrition Child||Fresenius Kabi||December 18 2019||Phase 4|
Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.
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