1-Triacontanol

Catalog No.S5172 Synonyms: n-Triacontanol, Melissyl alcohol, Myricyl alcohol

For research use only.

1-Triacontanol (n-Triacontanol, Melissyl alcohol, Myricyl alcohol) is a fatty alcohol found in plant cuticle waxes and in beeswax. It is a growth stimulant for many plants, most notably roses.

1-Triacontanol Chemical Structure

CAS No. 593-50-0

Purity & Quality Control

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Biological Activity

Description 1-Triacontanol (n-Triacontanol, Melissyl alcohol, Myricyl alcohol) is a fatty alcohol found in plant cuticle waxes and in beeswax. It is a growth stimulant for many plants, most notably roses.
In vivo The area under concentration-time curve AUC0-6 h and AUC0-∞ for 1-Triacontanol (TA) at 60 mg/kg are 87.737±13.574 and 93.617±17.62, respectively. The mean residence time is 3.25 ± 0.17 h. In addition, the elimination half-lives (t1/2) are (2.37±1.23, 1.27±0.49, 2.07±0.93) h after single oral administration of 30, 60 and 120 mg/kg of TA. After oral administration, TA is extensively distributed in stomach and intestine. The majority of TA excrete via feces, and its accumulative excretion ratio during the period of 72 h is 26.68 ± 7.14%, but only 0.0023 ± 0.0015% and 0.0027 ± 0.0006% for urines and bile, respectively. The absolute bioavailability (F, %) of TA is about 2.0%. TA is regarded as a promising anti-cancer compound with less or no toxicity. Due to low bioavailability and undesirable half-life[1].

Protocol (from reference)

Animal Research:

[1]

  • Animal Models: Sprague-Dawley rats
  • Dosages: 60 mg/kg
  • Administration: oral administration

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight 438.81
Formula

C30H62O

CAS No. 593-50-0
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCO

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Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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