PREP

Inhibitory Selectivity

PREP Products

Catalog No. Information Product Use Citations Product Validations
S2268

Baicalein

Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor.

S2269

Baicalin

Baicalin is a known prolyl endopeptidase inhibitor and affects the GABA receptors.

S2396

Salidroside

Salidroside (Rhodioloside), a phenylpropanoid glycoside isolated from Rhodiola rosea, has been reported to have a broad spectrum of pharmacological properties. Salidroside is a prolyl endopeptidase inhibitor. Salidroside alleviates cachexia symptoms in mouse models of cancer cachexia via activating mTOR signalling. Salidroside protects dopaminergic neurons by enhancing PINK1/Parkin-mediated mitophagy.

S0842New

SP-13786

SP-13786 (UAMC-1110)(compound 60) is a potent and selective inhibitor of fibroblast activation protein (FAP) and prolyl oligopeptidase (PREP) with IC50 of 3.2 nM and 1.8 μM, respectively.

S3249New

Corypalmine

Corypalmine ((R)-(+)-Corypalmine), an alkaloid isolated from Stephania cepharantha, is an inhibitor of prolyl endopeptidase/oligopeptidase (PREP/POP) with IC50 of 128.0 μM.

Catalog No. Information Product Use Citations Product Validations
S2268

Baicalein

Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor.

S2269

Baicalin

Baicalin is a known prolyl endopeptidase inhibitor and affects the GABA receptors.

S2396

Salidroside

Salidroside (Rhodioloside), a phenylpropanoid glycoside isolated from Rhodiola rosea, has been reported to have a broad spectrum of pharmacological properties. Salidroside is a prolyl endopeptidase inhibitor. Salidroside alleviates cachexia symptoms in mouse models of cancer cachexia via activating mTOR signalling. Salidroside protects dopaminergic neurons by enhancing PINK1/Parkin-mediated mitophagy.

S0842New

SP-13786

SP-13786 (UAMC-1110)(compound 60) is a potent and selective inhibitor of fibroblast activation protein (FAP) and prolyl oligopeptidase (PREP) with IC50 of 3.2 nM and 1.8 μM, respectively.

S3249New

Corypalmine

Corypalmine ((R)-(+)-Corypalmine), an alkaloid isolated from Stephania cepharantha, is an inhibitor of prolyl endopeptidase/oligopeptidase (PREP/POP) with IC50 of 128.0 μM.