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Ephrin receptor

Other Protein Tyrosine Kinase Related Inhibitors

VEGFR EGFR c-Met PDGFR CSF-1R IGF-1R c-Kit ALK Tie-2 HER2
Cat.No. Product Name Information Product Use Citations Product Validations
S2202 NVP-BHG712 NVP-BHG712 is a specific EphB4 inhibitor with ED50 of 25 nM that discriminates between VEGFR and EphB4 inhibition; this compound also shows activity against c-Raf, c-Src and c-Abl with IC50 of 0.395 μM, 1.266 μM and 1.667 μM, respectively.
BMC Oral Health, 2025, 25(1):118
Nat Commun, 2024, 15(1):5894
Apoptosis, 2024, 10.1007/s10495-024-02042-4
Verified customer review of NVP-BHG712
S6515 ALW II-41-27 ALW II-41-27 (compound 7) is a potent inhibitor of Eph receptor tyrosine kinase with Kd of 12 nM for EphA2.
Cell Death Differ, 2025, 10.1038/s41418-025-01536-1
Sci Rep, 2025, 15(1):24245
Biol Pharm Bull, 2025, 48(2):172-176
S0256 Ehp-inhibitor-1 Ehp-inhibitor-1 (Ehp inhibitor 2) is an Eph family tyrosine kinase inhibitor that targets Eph receptors.
King's College London, 2023,
E2835 NVP-BHG712 isomer NVP-BHG712 isomer, a regioisomer of NVP-BHG712, shows conserved non-bonded binding to EphA2 and EphB4.
E0614 AWL-II-38.3 AWL-II-38.3 is a potent Ephrin type-A receptor 3 (EphA3) kinase inhibitor.
S8573 Sitravatinib (MGCD516) Sitravatinib (MGCD516, MG-516) is a novel small molecule inhibitor targeting multiple RTKs involved in driving sarcoma cell growth, including c-Kit, PDGFRβ, PDGFRα, c-Met, and Axl.
Commun Biol, 2025, 8(1):1185
Res Sq, 2025, rs.3.rs-6431257
JCI Insight, 2022, e148717

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